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32. Venkatesh G. Electrocardiogram (ECG) as a diagnostic tool for the assessment of Cardiovascular status in alcoholics. Biomedical Research 2011;22:333-337.

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50. Cevik Y, Tanriverdi F, Delice O, Kavalci C, Sezigen S. Reversible increases in QT dispersion and P wave dispersion during carbon monoxide intoxication. Hong Kong Journal of Emergency Medicine 2010;17:441. 51. Satran D, Henry CR, Adkinson C, Nicholson CI, Bracha Y, Henry TD.

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56. Magnani JW, Wang N, Nelson KP, Connelly S, Deo R, Rodondi N, et al. The electrocardiographic pr interval and adverse outcomes in older adults: The health, aging and body composition study. Circulation: Arrhythmia and Electrophysiology 2012:CIRCEP. 112.975342.

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60. Baja ES, Schwartz JD, Wellenius GA, Coull BA, Zanobetti A, Vokonas PS, et al. Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the normative aging study. 2010.

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63. Lippi G, Rastelli G, Meschi T, Borghi L, Cervellin G. Pathophysiology, clinics, diagnosis and treatment of heart involvement in carbon monoxide poisoning. Clinical biochemistry 2012;45:1278-1285.

64. Zareba W, Nomura A, Couderc JP. Cardiovascular effects of air pollution: what to measure in ECG? Environmental health perspectives 2001;109:533. 65. Van Hee VC, Szpiro AA, Prineas R, Neyer J, Watson K, Siscovick D, et al. Association of long-term air pollution with ventricular conduction and repolarization abnormalities. Epidemiology (Cambridge, Mass) 2011;22:773.

66. Nautiyal J, Garg M, Kumar M, Khan A, Thakur J, Kumar R. Air Pollution and Cardiovascular Health in Mandi-Gobindgarh, Punjab, India - A Pilot Study. International Journal of Environmental Research and Public Health 2007;4:268-282.

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69. Ren C, Park SK, Vokonas PS, Sparrow D, Wilker E, Baccarelli A, et al. Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution. Epidemiology (Cambridge, Mass) 2010;21:198.

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72. Mills NL, Törnqvist H, Gonzalez MC, Vink E, Robinson SD, Söderberg S, et al. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. New England Journal of Medicine 2007;357:1075-1082.

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LAMPIRAN

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Lampiran 2. Persetujuan Setelah Penjelasan/Informed Consent.

JUDUL PENELITIAN :

HUBUNGAN ANTARA PAPARAN ASAP PEMBAKARAN LILIN BATIK DENGAN GAMBARAN EKG PENGRAJIN BATIK TULIS

PELAKSANA : SEKAR ARUM N. K. (MAHASISWA FK UNDIP)

INFORMED CONSENT Yth. Ibu/Saudari : ………

Nama saya Sekar Arum N. K. , saya mahasiswa Program Studi S1 Pendidikan Dokter Fakultas Kedokteran UNDIP. Saya melakukan penelitian berjudul Hubungan antara Paparan Asap Pembakaran Lilin Batik dengan Gambaran EKG Pengrajin Batik Tulis. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara paparan asap pembakaran lilin batik dengan gambaran EKG pengrajin batik tulis yang dilihat dari perbedaan gambaran EKG antara kelompok pengrajin batik tulis dengan kelompok kontrol serta hubungan antara lama paparan dengan perubahan gambaran EKG. Apabila Ibu/Saudari setuju menjadi peserta penelitian maka ada beberapa hal yang akan peneliti lakukan, yaitu:

- Pengambilan data mengenai pekerjaan, riwayat dan gejala penyakit jantung dan pembuluh darah, kebiasaan merokok, mengonsumsi alkohol dan obat-obatan dengan menggunakan kuesioner

- Pemeriksaan tekanan darah, denyut nadi, dan EKG

- Pengambilan data akan dilakukan dalam satu kali tatap muka

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mahasiswa Program Studi S1 Pendidikan Dokter FK UNDIP (HP 082137284614). Terima kasih atas kerjasama Ibu/Saudari.

Setelah mendengar dan memahami penjelasan tentang penelitian, dengan ini saya menyatakan:

Nama : ... Usia : ... Jenis kelamin : Laki-laki / Perempuan*

Pekerjaan : ... Alamat : ... Menyatakan : SETUJU / TIDAK SETUJU*

Semarang, ……….2015 Yang memberikan penjelasan Yang membuat pernyataan persetujuan

( ) ( ) *coret salah satu

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Lampiran 3. Kuesioner Penelitian

Kuesioner Penelitian

Tanggal :

Nama Pewawancara :

PENELITIAN HUBUNGAN ANTARA PAPARAN ASAP PEMBAKARAN LILIN BATIK DENGAN GAMBARAN EKG PENGRAJIN BATIK TULIS (Isi atau lingkari nomor jawaban)

1. No responden :

9. Tempat membatik : 1. Ruangan terbuka (tidak berdinding) 2. Ruangan tertutup (berdinding) 10. Apakah memiliki

pekerjaan lain yang

11. Adakah riwayat penyakit

13. Adakah kebiasaan merokok atau menghisap tembakau?

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14. Adakah kebiasaan mengonsumsi

e. Segmen ST : normal/tidak normal

f. Gelombang T : normal/tidak normal

g. Denyut jantung : kali/menit

(normal/takikardi/bradikardi)

h. Aksis QRS : °

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Lampiran 5. Hasil analisis Means

Statistic Std. Error

Usia

Mean 43,70 1,246

95% Confidence Interval for Mean Lower Bound 41,15 Upper Bound 46,25

5% Trimmed Mean 43,61

Median 42,50

Variance 46,562

Std. Deviation 6,824

Minimum 31

Maximum 58

Range 27

Interquartile Range 8

Skewness ,052 ,427

Kurtosis -,078 ,833

IMT

Mean 26,118 ,9860

95% Confidence Interval for Mean Lower Bound 24,101 Upper Bound 28,134

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Median 25,813

Variance 29,164

Std. Deviation 5,4004

Minimum 17,2

Maximum 44,6

Range 27,4

Interquartile Range 5,9

Skewness 1,445 ,427

*. This is a lower bound of the true significance.

a. Lilliefors Significance Correction T-Test

Levene's Test for Equality of

Variances

t-test for Equality of

Means

F Sig. t df

Usia

Equal variances assumed ,393 ,536 ,555 28

Equal variances not assumed ,555 27,5

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Independent Samples Test

t-test for Equality of Means

Sig. (2-tailed) Mean Difference Std. Error

Difference

Usia Equal variances assumed ,583 1,400 2,522 Equal variances not assumed ,583 1,400 2,522

Independent Samples Test

t-test for Equality of Means

95% Confidence Interval of the Difference

Lower Upper

Usia

Equal variances assumed -3,766 6,566

Equal variances not assumed -3,770 6,570

NPar Tests

Mann-Whitney Test

Ranks

Pekerjaan N Mean Rank Sum of Ranks

IMT

Bukan pengrajin batik 15 17,80 267,00

Pengrajin batik 15 13,20 198,00

Total 30

Test Statisticsa

IMT

Mann-Whitney U 78,000

Wilcoxon W 198,000

Z -1,432

Asymp. Sig. (2-tailed) ,152

Exact Sig. [2*(1-tailed Sig.)] ,161b

a. Grouping Variable: Pekerjaan

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PR and QT interval

Descriptives

Statistic Std. Error

PR

Mean 155,00 2,903

95% Confidence Interval for Mean

Lower Bound 149,06

Upper Bound 160,94

5% Trimmed Mean 154,76

Median 152,50

Variance 252,897

Std. Deviation 15,903

Minimum 127

Maximum 186

Range 59

Interquartile Range 26

Skewness ,323 ,427

Kurtosis -,693 ,833

QT

Mean 385,43 4,090

95% Confidence Interval for Mean Lower Bound 377,07 Upper Bound 393,80

5% Trimmed Mean 384,70

Median 387,00

Variance 501,771

Std. Deviation 22,400

Minimum 351

Maximum 438

Range 87

Interquartile Range 37

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*. This is a lower bound of the true significance.

a. Lilliefors Significance Correction T-Test

Levene's Test for Equality

of Variances

t-test for Equality of Means

F Sig. t df

PR Equal variances assumed 1,762 ,195 -,636 28 Equal variances not assumed -,636 26,173

QT

Equal variances assumed ,232 ,634 2,193 28

Equal variances not assumed 2,193 27,505

Independent Samples Test

t-test for Equality of Means

Sig. (2-tailed) Mean Difference Std. Error

Difference

PR

Equal variances assumed ,530 -3,733 5,867

Equal variances not assumed ,530 -3,733 5,867

QT Equal variances assumed ,037 16,867 7,690 Equal variances not assumed ,037 16,867 7,690

Independent Samples Test

t-test for Equality of Means

95% Confidence Interval of the Difference

Lower Upper

PR

Equal variances assumed -15,752 8,285

Equal variances not assumed -15,790 8,323

QT

Equal variances assumed 1,115 32,618

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PR

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Crosstabs

Pekerjaan * Interpretasi Crosstabulation

Interpretasi Total

Tidak normal Normal

Pek

Value 95% Confidence

Interval

Lower Upper

Odds Ratio for Pekerjaan (Pengrajin batik / Bukan

pengrajin batik)

16,000 1,656 154,59

5

For cohort Interpretasi = Tidak normal 8,000 1,136 56,330

For cohort Interpretasi = Normal ,500 ,286 ,873

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Lampiran 7. Biodata mahasiswa

Identitas

Nama : Sekar Arum Nuring Kurnia

NIM : 22010111130124

Tempat, tanggal lahir : Semarang, 17 April 1994

Jenis kelamin : Perempuan

Alamat : Jl. Tembalang Selatan III, Villa Mutiara E3

Nomor HP : 082137284614

Email : sekararumkurnia@gmail.com

Riwayat Pendidikan

SD : SDN 03 Purwodadi Lulus tahun 2005

SMP : SMPN 1 Purwodadi Lulus tahun 2008

SMA : SMA Semesta Semarang Lulus tahun 2011

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