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An American Heart

Association Journal

August 29, 2017 Volume 136 Number 9

Circulation

FRAME OF REFERENCE

Perspective

Aspirin Monotherapy Should Not Be Recommended for Cardioprotection in Patients With

Symptomatic Peripheral Artery Disease

785

Eric P. Brass, MD, PhD; William R. Hiatt, MD

ORIGINAL RESEARCH ARTICLES

Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion,

Rupture, and Need for Surgical Repair

787

The MA3RS Study Investigators

Incident Cardiovascular Disease Among Adults With Blood Pressure <140/90 mm Hg

798

Gabriel S. Tajeu, DrPH; John N. Booth III, PhD; Lisandro D. Colantonio, MD, PhD; Rebecca F. Gottesman, MD, PhD; George Howard, DrPH; Daniel T. Lackland, DrPH; Emily C. O’Brien, PhD; Suzanne Oparil, MD; Joseph Ravenell, MD; Monika M. Safford, MD; Samantha R. Seals, PhD; Daichi Shimbo, MD; Steven Shea, MD; Tanya M. Spruill, MD; Rikki M. Tanner, PhD; Paul Muntner, PhD

Editorial

Maximizing Cardiovascular Event Reduction by Expanding and Intensifying the Targets

813

Boback Ziaeian, MD, PhD; Gregg C. Fonarow, MD

Platelets Express Activated P2Y

12

Receptor in Patients With Diabetes Mellitus

817

Liang Hu, PhD; Lin Chang, BS; Yan Zhang, MD, PhD; Lili Zhai, MS; Shenghui Zhang, MD, PhD; Zhiyong Qi, MD;

Hongmei Yan, MD, PhD; Yan Yan, MD, PhD; Xinping Luo, MD, PhD; Si Zhang, MD, PhD; Yiping Wang, PhD; Satya P. Kunapuli, PhD; Hongying Ye, MD, PhD; Zhongren Ding, MD, PhD

Dedifferentiation, Proliferation, and Redifferentiation of Adult Mammalian Cardiomyocytes

After Ischemic Injury

834

Wei Eric Wang, MD, PhD; Liangpeng Li, MD; Xuewei Xia, MS; Wenbin Fu, MD; Qiao Liao, MS; Cong Lan, MD; Dezhong Yang, MD; Hongmei Chen, MD; Rongchuan Yue, MD, PhD; Cindy Zeng; Lin Zhou, MD, PhD; Bin Zhou, PhD; Dayue Darrel Duan, MD, PhD; Xiongwen Chen, PhD; Steven R. Houser, PhD; Chunyu Zeng, MD, PhD

STATE OF THE ART

In Depth

Cardiovascular Actions and Clinical Outcomes With Glucagon-Like Peptide-1 Receptor

Agonists and Dipeptidyl Peptidase-4 Inhibitors

849

Michael A. Nauck, MD; Juris J. Meier, MD; Matthew A. Cavender, MD, MPH; Mirna Abd El Aziz, MD; Daniel J. Drucker, MD

THE PULSE

From the

Circulation

Family

Highlights From the

Circulation

Family of Journals

871

PODCAST

CME

OPEN ACCESS

BRIDGING DISCIPLINES

On the Cover: Circulation Doodle

This month’s doodle is in honor of the Perseid Meteor Shower, which will be at its peak on August 12 and 13.

For more information about the doodle, go to http://circ.ahajournals.org/content/circulation-cover-doodle.

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PODCAST

CME

OPEN ACCESS

BRIDGING DISCIPLINES

CASES AND TRACES

ECG Challenge

A Lead to the Culprit

877

Haseeb Rahman, BMBCh; Bhavik Modi, MBBS; Howard Ellis, BSc; Satpal Arri, MBBS; Divaka Perera, MD

CORRESPONDENCE

Research Letter

The Low-Density Lipoprotein Receptor Genotype Is a Significant Determinant of the

Rebound in Low-Density Lipoprotein Cholesterol Concentration After Lipoprotein

Apheresis Among Patients With Homozygous Familial Hypercholesterolemia

880

Jean-Philippe Drouin-Chartier, MSc; André J. Tremblay, PhD; Jean Bergeron, MD, MSc; Benoît Lamarche, PhD; Patrick Couture, MD, PhD

Correspondence

Letter by Gabet et al Regarding Article, “Age-Specific Trends in Incidence, Mortality, and

Comorbidities of Heart Failure in Denmark, 1995 to 2012”

883

Amélie Gabet, MS; Yves Juillière, MD; Valérie Olié, PhD

Letter by Kaul et al Regarding Article, “Age-Specific Trends in Incidence, Mortality, and

Comorbidities of Heart Failure in Denmark, 1995 to 2012”

884

Padma Kaul, PhD; Justin A. Ezekowitz, MD; Finlay A. McAlister, MD

Response by Christiansen et al to Letters Regarding Article, “Age-Specific Trends in

Incidence, Mortality, and Comorbidities of Heart Failure in Denmark, 1995 to 2012”

886

Mia Nielsen Christiansen, MD; Lars Køber, MD, DSc; Charlotte Andersson, MD, PhD

CIRCULATION (ISSN 0009-7322) is published weekly except June and December by Wolters Kluwer Health, Inc. at 14700 Citicorp Drive, Bldg 3, Hagerstown, MD 21742. Business offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Production offices are located at 351 West Camden Street, Baltimore, MD 21201-2436. Individuals may subscribe for their personal use at the following rates for print subscriptions: $225 for AHA/ASA Domestic and International Members (excluding General Membership level), or $657 for domestic non-members and $1,006 for international non-members. AHA membership information can be found online at professional.heart.org. Periodicals postage paid at Hagerstown, MD, and additional mailing offices. POSTMASTER: Send address changes to CIRCULATION, American Heart Association, Wolters Kluwer Health, Inc., PO Box 1610, Hagerstown, MD 21740.

by guest on September 22, 2017

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136 (9)

Print ISSN: 0009-7322. Online ISSN: 1524-4539

Copyright © 2017 American Heart Association, Inc. All rights reserved.

is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231

Circulation

2017;136:785-887

Circulation.

http://circ.ahajournals.org/content/136/9.citation

World Wide Web at:

The online version of this article, along with updated information and services, is located on the

http://circ.ahajournals.org//subscriptions/

is online at:

Circulation

Information about subscribing to

Subscriptions:

http://www.lww.com/reprints

Information about reprints can be found online at:

Reprints:

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Permissions and Rights Question and Answer

this process is available in the

click Request Permissions in the middle column of the Web page under Services. Further information about

Office. Once the online version of the published article for which permission is being requested is located,

can be obtained via RightsLink, a service of the Copyright Clearance Center, not the Editorial

Circulation

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Requests for permissions to reproduce figures, tables, or portions of articles originally published

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