A.
Perhitungan Dosis Obat
Perhitungan Dosis Anthelmentik
Albendazole 5%
= 5 gr/100 ml = 50 mg/ml
Dosis per ekor mencit = 10 mg/kg BB
Dosis untuk mencit (BB = 20 gr)
= BB (kg) x Dosis (mg/kg BB)
Konsentrasi (mg/ml)
= 0,02 x 10
50
= 0,004 ml/ekor.
0,004 ml Albendazole diencerkan dengan menggunakan aquadest sebanyak 0,096
ml, maka dosis pemberian menjadi sebanyak 0,1 ml/ekor.
Perhitungan Dosis Antibiotik
Konsentrasi
= 125 mg/5 ml = 25 mg/ml
Dosis untuk anak-anak (BB = 25 kg) = 25 mg/kg BB
Dosis untuk mencit (BB = 20 gr)
= BB (kg) x Dosis (mg/kg BB)
Konsentrasi (mg/ml)
= 0,02 x 25
25
= 0,02 ml/ekor/hari
Sebanyak 0,02 ml AB dengan konsentrasi 25 mg/ml diencerkan dengan
menggunakan aquadest sebanyak 0,08 ml, maka dosis pemberian menjadi
sebanyak 0,1 ml/ekor.
Perhitungan Dosis Anti Protozoa
1 tablet @ 500 mg/50 kg BB
Dosis pemakaian
= 3x500 mg
= 30 mg/kg BB
50 kg
Dosis untuk mencit (BB = 20 gr)
= BB (kg) x Dosis (mg/kg BB)
Konsentrasi (mg/ml)
= 0,02 x 30
15
= 0,04 ml/ekor/hari
0,04 ml Anti Protozoa diencerkan dengan menggunakan aquadest sebanyak 0,06
ml, maka dosis pemberian menjadi sebanyak 0,1 ml/ekor.
Perhitungan Dosis Habbatussauda
Dosis Preventif
Manusia BB 50 kg 15 ml/hari = 0,3 ml/kgBB/hari x 2 sendok makan
(sdm)
Mencit BB 30 gr 30 gr x 0,6 ml x 3 kali/hari = 0,054 = 0,1 ml/hari
1000gr
Dosis Kuratif
Asumsinya untuk pengobatan yaitu 2 kali dari dosis preventif, maka yang
diberikan yaitu 0,2 ml.
Perhitungan Dosis Kombinasi Habbatussauda dengan Madu
Madu untuk manusia dengan BB 50 kg 3 sdm/hari 1 sdm = 15 ml, 1 hari =
45 ml = dosis preventif.
Kombinasi habbatussauda dengan madu diberikan sebanyak 0,3 ml karena
perbandingan antara madu : habbatussauda = 20:1.
B. Data Hasil Olahan Statistik Post Hoc Tests
Homogeneous Subsets LUAS OVARIUM Duncan PERLAKUAN N
Subset for alpha = .05 1 HS Kuratif 3 1.4033 HS Preventif 3 1.4700 Kontrol Negatif 2 1.7000 HS Madu 3 2.0900 Sig. .406
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 2.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total
N Percent N Percent N Percent LUAS OVARIUM * PERLAKUAN 11 91.7% 1 8.3% 12 100.0% Report PERLAKUAN LUAS OVARIUM Kontrol Negatif Mean 1.7000 N 2 Std. Deviation .18385 HS Preventif Mean 1.4700 N 3 Std. Deviation 1.27330 HS Kuratif Mean 1.4033 N 3 Std. Deviation .38423 HS Madu Mean 2.0900 N 3 Std. Deviation .87178 Total Mean 1.6627 N 11 Std. Deviation .77171
Post Hoc Tests Homogeneous Subsets CL Duncan PERLAKUAN N
Subset for alpha = .05 1 Kontrol negatif 2 3.4100 HS Madu 3 3.5133 HS Kuratif 3 4.4833 HS Preventif 3 5.1800 Sig. .462
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 2.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent
CL * PERLAKUAN 11 100.0% 0 .0% 11 100.0% Report CL PERLAKUAN Mean N Std. Deviation Kontrol negatif 3.4100 2 3.28098 HS Preventif 5.1800 3 2.73896 HS Kuratif 4.4833 3 2.43083 HS Madu 3.5133 3 1.74477 Total 4.2136 11 2.22391
Post Hoc Tests
Homogeneous Subsets
LUAS FOLIKEL TERSIER Duncan
PERLAKUAN
N
Subset for alpha = .05 1 HS Kuratif 12 17411.2317 HS Preventif 12 17879.3417 Kontrol negatif 8 22386.5625 HS Madu 12 27935.8008 Sig. .112
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 10.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent LUAS FOLIKEL TERSIER *
PERLAKUAN 44 57.9% 32 42.1% 76 100.0%
Report
LUAS FOLIKEL TERSIER PERLAKUAN Mean N Std. Deviation Kontrol negatif 22386.5625 8 15516.69910 HS Preventif 17879.3417 12 11480.60927 HS Kuratif 17411.2317 12 8805.27349 HS Madu 27935.8008 12 17845.31285 Total 21313.8407 44 13935.74633
Post Hoc Tests
Homogeneous Subsets
REGENERASI Duncan
PERLAKUAN N
Subset for alpha = .05
1 2 Kontrol negatif 10 30.5130 HS Preventif 15 41.2082 41.2082 HS Kuratif 15 42.2238 42.2238 HS Madu 15 57.0853 Sig. .302 .162
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 11.958.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent REGENERASI * PERLAKUAN 55 100.0% 0 .0% 55 100.0% Report REGENERASI PERLAKUAN Mean N Std. Deviation Kontrol negatif 30.5130 10 18.38451 HS Preventif 41.2082 15 35.56550 HS Kuratif 42.2238 15 26.84201 HS Madu 57.0853 15 19.99058 Total 44.1553 55 26.78796
Post Hoc Tests Homogeneous Subsets KELENJAR UTERUS Duncan PERLAKUAN N
Subset for alpha = .05 1 Kontrol Negatif 10 9.4000 HS Preventif 15 11.6227 HS Kuratif 15 12.7500 HS Madu 15 13.1333 Sig. .106
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 13.333.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent KELENJAR UTERUS * PERLAKUAN 55 100.0% 0 .0% 55 100.0% Report PERLAKUAN KELENJAR UTERUS Kontrol Negatif Mean 9.4000 N 10 Std. Deviation 5.15139 HS Preventif Mean 11.6227 N 15 Std. Deviation 6.46158 HS Kuratif Mean 12.7500 N 15 Std. Deviation 4.18381 HS Madu Mean 13.1333 N 15 Std. Deviation 7.09997 Total Mean 10.5818 N 55 Std. Deviation 6.82232
Post Hoc Tests Homogeneous Subsets SEL GOBLET Duncan PERLAKUAN N
Subset for alpha = .05 1 Kontrol negatif 60 .0000 HS Preventif 90 .0000 HS Kuratif 90 .0000 HS Madu 90 .0222 Sig. .099
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 80.000.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent SEL GOBLET * PERLAKUAN 330 80.5% 80 19.5% 410 100.0% Report SEL GOBLET PERLAKUAN Mean N Std. Deviation Kontrol negatif .0000 60 .00000 HS Preventif .0000 90 .00000 HS Kuratif .0000 90 .00000 HS Madu .0222 90 .14823 Total .0061 330 .07773
Post Hoc Tests Homogeneous Subsets FOLIKEL PRIMER Duncan PERLAKUAN N
Subset for alpha = .05 1 HS Madu 30 .4107 Kontrol negatif 20 .3830 HS Preventif 30 .8605 HS Kuratif 30 .6867 Sig. .083
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 26.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
FOLIKEL SEKUNDER Duncan
PERLAKUAN N
Subset for alpha = .05
1 2 HS Madu 30 .4333 Kontrol negatif 20 .4320 HS Kuratif 30 .5637 .5637 HS Preventif 30 .9523 Sig. .160 .70
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 26.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
FOLIKEL TERSIER Duncan PERLAKUAN N
Subset for alpha = .05 1 Kontrol negatif 20 .2610 HS Madu 30 .2773 HS Kuratif 30 .3100 HS Preventif 30 .4190 Sig. .149
Means for groups in homogeneous subsets are displayed. a Uses Harmonic Mean Sample Size = 26.667.
b The group sizes are unequal. The harmonic mean of the group sizes is used. Type I error levels are not guaranteed.
Case Processing Summary
Cases
Included Excluded Total N Percent N Percent N Percent PRIMER * PERLAKUAN 110 100.0% 0 .0% 110 100.0% SEKUNDER * PERLAKUA 110 100.0% 0 .0% 110 100.0% TERSIER * PERLAKUA 110 100.0% 0 .0% 110 100.0% Report
PERLAKUAN PRIMER SEKUNDER TERSIER Kontrol negatif Mean .3830 .4320 .2610 N 20 20 20 Std. Deviation .32366 .34958 .22492 HS Preventif Mean .8605 .9523 .4190 N 30 30 30 Std. Deviation .63251 .74208 .12354 HS Kuratif Mean .6867 .5637 .3100 N 30 30 30 Std. Deviation .39579 .41432 .26417 HS Madu Mean .4107 .4333 .2773 N 30 30 30 Std. Deviation .37348 .31578 .22442 Total Mean .5466 .4425 .3219 N 110 110 110 Std. Deviation .53246 .43677 .36145