COURSE CONTRACT
VETERINARY FARMACOTHERAPY & TOXICOLOGY COURSE BACHELOR OF VETERINARY MEDICINE
1. Course : VETERINARY FARMACOTHERAPY & TOXICOLOGY
2. Course Code : FAT 403
3. Study load : 3 SKS
4. Semester : IV
5. Study Program : Bachelor of Veterinary Medicine 6. Prerequisites : Veterinary Pharmacology 7. Course Description
: Veterinary Pharmacotherapy and Toxicology courses are held face-to-face interaction and practicum for one semester. In face to face interaction will discuss about class of drugs, chemical structure, pharmacokinetics, pharmacodynamics, mechanism of action and side effects also interactions of various drugs and ingredients that can cause poisoning, clinical symptoms due to poisoning, toxins working mechanism and how to overcome poisoning. At the end of lecture, mastery of material will evaluate by multiple choice exams.
8. Person in Charge : Dr.Rochmah Kurnijasanti,drh.,MSi 9. Lecturer 1. Prof.Dr.D.K.Meles., drh.,MS.
2. Prof.Sri Agus Sudjarwo, drh.,PhD.
3. Dr.Iwan Sahrial Hamid.,drh.,MSi.
10. Meeting Day / Hour / Room
Veterinary Pharmacotherapy and Toxicology Material Class A & B: Room 4A dan 4B, Jum’at, 07.00 – 08.50 WIB Class C: Room junction 3, Jum’at, 09.00 – 10.50 WIB Class D: Room 3B, Kamis, 07.00 – 08.50 WIB Class E: Room 3D, Selasa, 07.00 – 08.50 WIB Practice: Lab. PK, Jum’at, 13.00 – 16.00 WIB 11. Soft Skills attribute 1. Self-motivation/initiative
2. Work ethic/dependability 3. Critical thinking
4. Questioning skills 5. Academic/learning skills 6. Teaching/training skills 12. Acheivement of Graduate
Learning
LO 4 : Analyze various kinds of medicines based on chemical structures, pharmacokinetics, pharmacodynamics, and the therapy to define drug of choice in line with caused agent of sick animals
13. Achievement of Course Learning
: - Students are able to explain about class of drugs, chemical structure, pharmacokinetics, pharmacodynamics, drugs action mechanism and side effects also interactions of
various drugs
- Students are able to explain about the ingredients that can cause poisoning, clinical symptoms due to poisoning, toxins working mechanism and how to overcome due to poisoning - Students are responsible for their own work and can be
given responsibility for achieving shared results 14. Sub Learning Outcomes:
After attending the veterinary pharmacotherapy and toxicology face-to-face interaction, students will be able to explain the interests and uses of pharmacotherapy and toxicology in livestock, poultry, dogs and cats. Special information can be described as follows:
1. Students know the rules that must be followed and adhered together during lectures, Knowing the meaning and scope: History of courses, lecturers and lecture schedules;
Course benefits and descriptions; Objectives of the course; Course evaluation; Other explanations such as percentage presentations, reading material and assignments
2. Students can explain the meaning, the scope of drug pharmacotherapy which includes the pathogenesis of several diseases related to drugs given, effects, dosage, drugs mechanism of action, toxic substances in drugs, toxicokinetics, toxicodynamics, how to treat animal poisoned in general also toxicity testing procedures in experimental animals.
3. Students know and able to explain drugs that often cause poisoning, clinical symptoms due to poisoning, the toxic substances mechanism of action and how to handle due to drug poisoning
4. Students know and able to explain the materials or ingredients that can cause poisoning, clinical symptoms due to poisoning, the toxic substances mechanism of action and how to handle due to pesticide poisoning.
5. Students are able to explain and know the drugs that often cause poisoning, clinical symptoms due to poisoning, the toxic substances mechanism of action and treating due to poisoning of poisonous animals.
6. Students are able to explain and know the ingredients that can cause poisoning, clinical symptoms due to poisoning, the toxic substances mechanism of action and treating due to plant poisoning.
7. Students are able to explain and know the ingredients that can cause poisoning, clinical symptoms due to poisoning, the toxic substances mechanism of action and treating due to heavy metal poisoning and the environment.
8. Students are able to explain the mechanism and effects caused by giving more than one drug.
9. Students are able to explain the chemical structures, class, activity and spectrum, the pharmacokinetics, pharmacodynamics and side effects of antacids and antidiarrhea.
10. Students are able to explain the chemical structures, class of drugs, activity and spectrum, resistance, pharmacokinetics, pharmacodynamics and side effects of antibiotics. Explain about the chemical structures, class of drugs, activity and spectrum, pharmacokinetics, pharmacodynamics and side effects, synergism, antagonism and combination effects of
sulfonamides and trimethoprim. Also describes the chemical structure, class of drugs, activity and spectrum, pharmacokinetics, pharmacodynamics and side effects of tuberculostatics.
11. Students are able to explain the chemistry structures, class of drugs, activity and spectrum, pharmacokinetics, pharmacodynamics and side effects of antiprotozoa.
12. Students are able to explain the chemistry structure, class of drugs, activity and spectrum, pharmacokinetics, pharmacodynamics and side effects of antivirals.
13. Students are able to explain the chemical structure, class of drugs, activity and spectrum, pharmacokinetics, pharmacodynamics and side effects of anticancer
15. Benefits of Courses
Pharmacotherapy is a part of pharmacology which means the drugs used for healing or treatment purposes. The use of drugs is an activity related to the selection and use rationally and correctly for the treatment purposes. Prevention and diagnosis of a disease based on the rules of knowledge about drugs, while treatment is an effort to cure the disease. By studying pharmacotherapy, it can be obtained the knowledge about pharmacokinetics, pharmacodynamics, side effects, toxic effects, indications, dosages and drug interactions as well as knowledge about the pathophysiology and pathogenesis of treated diseases.
Besides that, by studying this course, knowledge of toxicology was obtained including the knowledge of poisons, toxicity, toxic substances mechanism, clinical symptoms caused by poisoning and knowledge of handling poisoning and test the toxicity of a drugs.
16. Course Strategy
In lectures, students are expected to learn in advance the prerequisite courses that have been followed and read the instructional material / hand out that has been determined first.
The lecturer only gives outlines of the subject or sub-subject or gives an explanation of the material included in veterinary pharmacotherapy and toxicology, then students are expected to ask questions that are less clear and also answer the lecturer questions.
Students will also given assignments besides midterms and final semester examinations 17. Lecture Material or Reading
1. Sulistia et al. 2010. Pharmacology and Therapy. 5Ed. Departement of Pharmacology, Faculty of Medicine, Universitas Indonesia
2. Goodman and Gilmans. 2011. The Pharmacological Basis of Therapeutics. 12th ed. Mac Millan Publishing Company
3. Riviere, J.E. and Papich, M.G. Veterinary Pharmacology and Therapeutics. 9th ed. Wiley Blackwell Publisher.
4. Nicholas, H.B and Leslie, E.M. 1992. Veterinary Pharmacology and Therapeutics. 6th ed.
Iowa state University Press
5. Plumlee, K. 2007. Clinical Veterinary Toxicology. Elsevier Science Health Publisher.
6. Clarke and Clarke (2001) toxicologi veteriner 4 th ed. A Lange Medical
7. Klaasen C.D. and wattkins, J., B, (2003). Essential 7 th ed. Mc Graw Hill- Toronto
8 Kurnijasanti, R., Meles, DK., Sudjarwo, SA., Hamid, IS. 2017. . Textbook of Veterinary Pharmacotherapy and Toxicology. Duta Persada..
18. Lecture Assignments Group Assignments:
Week 1 - 7 of each group that has been determined, collects the group assignments with the topic that given by supervisor before Midterms semester examinations.
Individual Assignments:
Week 15: Every student is required to collect the assignments according to the topics that given by supervisor.
19. Assessment Criteria Scoring System
Each test is given a raw score in the form of 0 to 100. Especially for the final score, the assessment is given in 7 grades, namely: A, AB, B, BC, C, D and E.
The final score of a course is determined from the combined results of the evaluation of all test scores held by the lecturer concerned. Examples of test weights (quiz), (structured assignments), (Practical exam), (soft skills), (MSE), (LSE) tests are 1.5: 1.5: 2: 1: 2: 3.
Example:
X students take the Pharmacotherapy and Veterinary toxicology exam, the value for each exam is as follows:
Quiz test = 70
MSE = 70
Assignment = 65
LSE = 75
Practical exam = 60 Softskill = 80
Then the final value (still in raw value)
Processing Final Score (raw score / in the form of numbers) becomes a Quality Score in the form of letters processed in 7 (seven) grades. From the final score (raw score), the mean value (X) can be processed. The grouping of values is done using the ASSESSMENT REFERENCE ASSESSMENT (PAP) as follows
(70x1,5) + (65x1,5) + (60 x 2) + (70 x 2) + (75 x 3)+ 80 1,5 + 1,5 + 2 + 2 + 3+1
767,5
11 = 69,77
Raw Score Letter Grade
≥ 75 70 – 74.9 65 – 69.9 60 – 64.9 55 – 59.9 40 – 54.9
< 40
A AB
B BC
C D E
The score presentation from the processing results in above uses 7 ratings, as follows:
Letter Grade Quality Score A
AB B BC
C D E
4 3,5
3 2,5
2 1 0 20. Etc
• Students are allowed to attend the LSE if 75% are present in the lecture (min 9 times present, for new students) and 50% are present (for repeating students)
• If you do not take quiz, uts, you must have a doctor's certificate and a maximum of 1 week after quiz / uts / you will immediately take the follow-up exam
• Collection of structured assignments and practicum reports maximum of 1 week from the provision of assignments / practical activities
• Type question for quiz: essays
• For MSE and LSE : multiple choice
EDUCATION SCHEDULE
Study Program : Bachelor of Veterinary Medicine
Lecturer : Prof.Dr. IDK. Meles.Drh., MS (DKM), Prof. Sri Agus Sudjarwo, Drh.,PhD (SAS),
Dr. Iwan Sahrial Hamid.,Drh.,Msi (ISH), Dr.Rochmah Kurnija Santi,Drh., Msi (RKS)
Course : Veterinary Pharmacology and Toxicology Day/time : Thursday / 07.00-8.50 (RK. Pasca)
Class : E .
Meet
ing day/ date
Realization of SAP
Lecturer Title of Chapter Material Details
1 Thursday 02– 6 – 2018
Learning Contract Course Benefits, Course Descriptions, Lecture Schedules, Results Assessment, Reading Materials, Tasks
RKS 2 Thursday
09– 2 – 2018
Introduction Pharmacotherapy antibiotic,
anthelmintic, antacid, antidiarrheal, chemotherapy, antiprotozoa, antiviral and anticancer drugs, Definition and toxicological goals, toxicokinetics, Toxicodynamics, General poisoning treatment, Toxicity tests in experimental animals
DKM
3 Thursday 16– 2 – 2018
Drugs toxicology Acetaminophen poisoning, aspirin, ibuprofen, anticoagulants,
antihistamines and decongestants, drugs cholecalciferol, cocaine, marihuana, striknin, tricyclic antidepressants
RKS
4 Thursday 23– 2 – 2018
Pesticide Toxicology
Toxicology of insecticides, toxicicology of herbicides, toxicology of
rodenticides, viralid toxicology
ISH
5 Thursday 30 – 2 –2018
Heavy Metal and Environmental Toxicology
Lead poisoning, arsenic, mercury, Cadmium, copper, iron, carbon monoxide, sulfur oxide
SAS
6 Thursday 06 – 3 – 2018
Toxicology of Poisonous Animals
Classification of poisonous animals, snake venom, scabies poison, poisonous frogs, poisonous fish
DKM
7 Thursday 13– 3 – 2018
Toxic Plant Toxicology
Oxalat, Cyanida, Nitrate-nitrite, perirenal edema, teratogen plant,
photosensitization, plants that cause oral
DKM
irritation, emesis without diarrhea, emesis with diarrhea, gastroenteritis, convulsions, contain alkaloid beladona, affect the cardiovascular system, affect skeletal muscle tone
8 Tuesday 25-4-2018 Jam 9.45
MSE
Introduction, Drug Toxicology, Pesticides, Heavy Metals and the Environment, Toxic Animals, Toxic Plants
TIM
9 Thursday 04– 5– 2018
Drug Interaction Pharmacokinetic interactions Pharmacodynamic interactions
RKS 10 Friday
12– 5 –2018 (13.00-14.50)
Antacids and
Antidiarrhea Aluminum hydroxide (Al (OH) 3) Calcium carbonate
Tricilicate magnesium
SAS
11 Thursday 18–5 – 2018
Antibiotics and
Chemotherapy Penicillin and Cephalosporin Tetracycline and Chloramphenicol Aminoglycosides
Macrolide and Lincosamide
DKM
12 Friday 26–5 – 2018 (13.00-14.50)
Antiparasitic
(Anthelmintic) Befenium hydroxynaphthoate, Dietilcarbamazin, Diclorofen, Levamisole, Mebendazole, Niclosamide, Piperazine, Pirantel pamoat, Tiabendazole
Praziquantel
ISH
13 Friday 02- 6– 2018 (13.00-14.50)
Antiparasitic (anti protozoa)
Anticoxidiosis Antitripanosomiasis Antibabesiosis
ISH
14 Thursday 08– 6– 2018
Anti Virus Amantadine, Zidovudin
Ribavirin, Acyclovir, Idoxuridine, Metisoprinol, Gangsiclovir, Intervero
SAS
15 Thursday 15- 6– 2018
Anti cancer Alkylating agent, Antibiotics Anti mitotic (Vinca alkaloids) Hormone, Miscellaneous
Hidroxyurea, Cisplatin, Procarbazin, L- asparginase
RKS
16 Tuesday 4 Juli 2018 Jam: 9.45
LSE Drug Interaction, Antacids and Antidiare, Antibiotics and
Chemotherapy, Anthelmintics, Anti- protozoa, Antivirus, Anticancer
TIM
Surabaya, 20 Jan 2018 Validation by
Person in Charge Head of Departement Veterinary Pharmacotherapy and Toxicology
Dr.Rochmah Kurnijasanti, Drh. MSi Dr. Nove H, drh., MKes.
NIP.197007191996032002 NIP. 19651115 1995032001
