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Fig. E-1

Distribution of patients who underwent morphological analyses of the C1 vertebra within each age group.

Fig. E-2

Changes in the anterior ossific nucleus area, as a function of age.

COPYRIGHTÓBYTHEJOURNAL OFBONE ANDJOINTSURGERY, INCORPORATED RAO ET AL.

DEVELOPMENTALMORPHOLOGY ANDOSSIFICATIONPATTERNS OF THEC1 VERTEBRA http://dx.doi.org/10.2106/JBJS.L.01035

Page 1 of 3

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Fig. E-3

Correlation between the area of anterior nucleus ossification and mean width of bilateral neurocentral synchondroses.

Fig. E-4

Mean inner transverse diameter (and standard deviation) of the C1 vertebra. Data were not different between two consecutive groups.

COPYRIGHTÓBYTHEJOURNAL OFBONE ANDJOINTSURGERY, INCORPORATED RAO ET AL.

DEVELOPMENTALMORPHOLOGY ANDOSSIFICATIONPATTERNS OF THEC1 VERTEBRA http://dx.doi.org/10.2106/JBJS.L.01035

Page 2 of 3

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TABLE E-1 Summary of Data Based on Different Age Groups

Age Group

Parameter 0-3 Years 3-6 Years 6-9 Years 9-12 Years 12-15 Years 15-18 Years

Mean data

Outer anteroposterior diameter(cm) 2.99 3.69 4.05 4.38 4.35 4.55

Inner anteroposterior diameter(cm) 2.22 2.78 3.09 3.03 3.01 3.33

Outer transverse diameter(cm) 4.99 6.01 6.76 7.42 7.38 7.86

Inner transverse diameter(cm) 2.24 2.38 2.48 2.26 1.97 1.95

Inner area(cm2) 4.34 6.27 6.98 6.65 6.58 7.35

Anterior ring height(cm) 0.76 0.77 0.89 1.02 1.04 1.15

Posterior ring height(cm) 0.63 0.58 0.74 1.00 0.85 1.19

Standard deviation data

Outer anteroposterior diameter(cm) 0.45 0.33 0.35 0.33 0.19 0.18

Inner anteroposterior diameter(cm) 0.46 0.30 0.15 0.19 0.12 0.22

Outer transverse diameter(cm) 0.88 0.38 0.40 0.42 0.86 0.60

Inner transverse diameter(cm) 0.27 0.41 0.15 0.35 0.14 0.39

Inner area(cm2) 1.35 1.23 0.57 0.70 0.96 1.19

Anterior ring height(cm) 0.18 0.12 0.13 0.09 0.07 0.14

Posterior ring height(cm) 0.17 0.16 0.07 0.19 0.08 0.12

TABLE E-2 Coefficients of Repeatability for Interobserver and Intraobserver Measurements

Parameter

Anteroposterior Diameter

Transverse

Diameter Width

Outer Inner Outer Inner Left Synchondrosis Right Synchondrosis Interobserver

Coefficients of repeatability 0.285 0.171 0.280 0.123 0.021 0.023

Percentage of mean 7.582 6.229 4.558 5.511 10.194 11.454

Intraobserver

Coefficients of repeatability 0.277 0.193 0.280 0.159 0.020 0.021

Percentage of mean 7.396 6.971 4.553 7.113 7.574 8.615

COPYRIGHTÓBYTHEJOURNAL OFBONE ANDJOINTSURGERY, INCORPORATED RAO ET AL.

DEVELOPMENTALMORPHOLOGY ANDOSSIFICATIONPATTERNS OF THEC1 VERTEBRA http://dx.doi.org/10.2106/JBJS.L.01035

Page 3 of 3

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