Supplemental Digital Content 1. Risk of early measles infection: Susceptibility and morbidity indicators
Risk factors 4.5 months: Risk of infection % (cases/N) 4.5-9 months: Rate of infection (cases/person- years (pyrs))
Ratio (95% CI)
Specific
susceptibility and herd immunity
Sex Female Male
Before 4.5 months 3.8 (30/781) 3.8 (28/743) 1.03 (0.62-1.71) 4.5 to 9 months 0.39 (53/135 pyrs) 0.33 (45/135 pyrs) 1.17 (0.79-1.73)
Mother’s age 15-24 25-44
Before 4.5 months 4.9 (36/739) 2.9 (21/733) 1.67 (0.99-2.82) 4.5 to 9 months 0.42 (54/128 pyrs) 0.29 (39/136 pyrs) 1.53 (1.02-2.31)
District Cuntum Old districts
Before 4.5 months 4.1 (22/543) 3.7 (36/981) 1.08 (0.64-1.82) 4.5 to 9 months 0.44 (41/93 pyrs) 0.32 (57/176 pyrs) 1.36 (0.91-2.03) Non-specific
susceptibility indicators
MUAC <130mm 130mm+
4.5 to 9 months 0.40 (18/45 pyrs) 0.36 (80/225 pyrs) 1.12 (0.67-1.86) Weight-Height- z-score WHZ <-2 WHZ >=-2
4.5 to 9 months 0.39 (5/13 pyrs) 0.36 (92/257 pyrs) 1.05 (0.43-2.57) Low birth weight <2.5 kg => 2.5 kg
Before 4.5 months 3.3 (3/90) 4.0 (37/919) 0.71 (0.25-2.06)
4.5 to 9 months 0.40 (5/13 pyrs) 0.34 (58/173 pyrs) 1.20 (0.50-2.89)
Breastfeeding No Yes
Before 4.5 months 0 (0/40) 3.9 (57/1480) 0
4.5 to 9 months 0.76 (7/9 pyrs) 0.35 (91/260 pyrs) 2.12 (1.06-4.26)
BCG Scar No Yes
Before 4.5 months 7.3 (20/275) 3.1 (38/1242) 2.30 (1.36-3.90) 4.5 to 9 months 0.38 (17/44 pyrs) 0.36 (81/225 pyrs) 1.09 (0.64-1.85) Morbidity indicators
at 4½ months
Fever at enrollment Yes No
4.5 to 9 months 0.66 (26/39 pyrs) 0.32 (72/228 pyrs) 2.02 (1.27-3.20) Respiratory illness at
enrollment
Yes No
4.5 to 9 months 0.99 (13/13 pyrs) 0.33 (84/255 pyrs) 2.87 (1.62-5.07) Diarrhoea at
enrollment
Yes No
4.5 to 9 months 0.24 (5/21 pyrs) 0.38 (93/245 pyrs) 0.62 (0.25-1.55)
