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Supplementary table 2a: Multilevel univariable logistic regression analysis showing factors associated with different respiratory viruses.

influenza A/B RSV A/B rhinovirus human metapneumovirus

Factor OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value

Age

< 6 months Ref Ref Ref Ref

6-23 months 4.55 (1.6, 12.92) 0.004 0.7 (0.43, 1.16) 0.171 0.57 (0.38, 0.85) 0.006 0.81 (0.37, 1.76) 0.600

24-59 months 2.13 (0.69, 6.6) 0.191 0.45 (0.25, 0.81) 0.008 0.76 (0.5, 1.17) 0.214 1.26 (0.57, 2.76) 0.564

Sex

Male Ref Ref Ref Ref

Female 0.84 (0.49, 1.45) 0.537 1.33 (0.88, 2.01) 0.177 1.04 (0.76, 1.41) 0.821 1.27 (0.73, 2.22) 0.393

Runny nose

No Ref Ref Ref Ref

Yes 0.82 (0.36, 1.88) 0.645 3.13 (1.12, 8.78) 0.03 0.84 (0.51, 1.38) 0.492 0.71 (0.31, 1.63) 0.417

Chest indrawing

No Ref Ref Ref Ref

Yes 1.61 (0.94, 2.76) 0.084 2.37 (1.56, 3.6) <0.001 1.11 (0.8, 1.54) 0.541 0.53 (0.26, 1.08) 0.079

Chest wheeze

No Ref Ref Ref Ref

Yes 0.81 (0.42, 1.56) 0.531 1.2 (0.75, 1.92) 0.444 1.7 (1.2, 2.4) 0.003 0.48 (0.21, 1.08) 0.077

Chest crepitations

No Ref Ref Ref Ref

Yes 0.89 (0.48, 1.64) 0.712 1.6 (0.93, 2.73) 0.089 1.34 (0.93, 1.93) 0.121 0.39 (0.22, 0.69) 0.001

Temp>38

No Ref Ref Ref Ref

Yes 3.89 (1.87, 8.11) <0.001 1.2 (0.55, 2.65) 0.645 0.96 (0.52, 1.78) 0.896 1.95 (0.79, 4.82) 0.149

Oxygen saturation

Normal Ref Ref Ref Ref

Low 0.78 (0.33, 1.87) 0.581 2.55 (1.51, 4.31) <0.001 0.89 (0.55, 1.42) 0.616 1.78 (0.86, 3.68) 0.12

Supplementary table 2b: Multilevel univariable logistic regression analysis showing factors associated with different respiratory viruses.

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OR – Odd ratio; CI – Confidence interval; Ref – Reference; p-Value – probability value

coronavirus adenovirus parainfluenza

Factor OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value

Age

< 6 months Ref Ref Ref

6-23 months 0.55 (0.29, 1.07) 0.081 1.09 (0.5, 2.39) 0.832 1.58 (0.89, 2.81) 0.116

24-59 months 0.56 (0.27, 1.16) 0.116 0.84 (0.35, 2.02) 0.700 1.38 (0.74, 2.55) 0.307

Sex

Male Ref Ref Ref

Female 0.63 (0.35, 1.12) 0.118 0.76 (0.41, 1.39) 0.37 0.83 (0.56, 1.24) 0.359

Runny nose

No Ref Ref Ref

Yes 1.51 (0.53, 4.29) 0.442 0.76 (0.31, 1.86) 0.551 0.9 (0.48, 1.7) 0.751

Chest indrawing

No Ref Ref Ref

Yes 0.68 (0.36, 1.3) 0.243 0.85 (0.44, 1.64) 0.625 0.7 (0.45, 1.1) 0.122

Chest wheeze

No Ref Ref Ref

Yes 1.16 (0.63, 2.15) 0.628 1.21 (0.62, 2.33) 0.577 0.82 (0.51, 1.33) 0.425

Chest crepitations

No Ref Ref Ref

Yes 1.48 (0.73, 3.00) 0.274 2.25 (0.94, 5.37) 0.069 0.86 (0.55, 1.34) 0.503

Temp>38

No Ref Ref Ref

Yes 0.24 (0.03, 1.77) 0.162 2.19 (0.88, 5.45) 0.091 1.36 (0.66, 2.81) 0.409

Oxygen saturation

Normal Ref Ref Ref

Low 1.41 (0.67, 2.98) 0.37 1.04 (0.43, 2.52) 0.93 1.12 (0.63, 2.01) 0.692

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