PDF Module 6 : Basic Pharmaceutical Compounding and Manufacturing/ BPCM (11.12)

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Module 6 : Basic Pharmaceutical Compounding and Manufacturing/ BPCM (11.12)

Degree Programme: Undergraduate Programme in Clinical and Community Pharmacy Title of Module: Basic Pharmaceutical Compounding and Manufacturing

Abbreviation: BPCM

Title of Class: FA2131 Basic Pharmaceutics

Semester: 3

Responsible for Module: Dr. Sasanti Tarini Darijanto

Lecturer:  Dr. Lucy D. N. Sasongko

 Dr. Rachmat Mauludin

Language: Indonesian Language

Assignment to Programme: Undergraduate Programme in Clinical and Community Pharmacy Compulsory Class, Semester 3

Class Type / Hours: Lecture / 2 h per week and Practicum / 4 h per week Workload:  Study time in class: 32 h

 Study time in laboratory : 48 h (within 12 weeks)

 Study time at home: 50 h

Credits: 4.17 ECTS

Requirements: Registered Student to Undergraduate Programme in Clinical and Community Pharmacy

Study Goals: Knowledge:

Describe and explain the proper and safe dosage form compounding practice, based on a given prescription

Skill:

Demonstrate the proper and safe dosage compounding based on a given prescription.

Competence:

Able to develop and compose pharmaceutical compounding knowledge and skill in various pharmaceutical work-fields

Content: Introduction, prescription, drug dosage, pharmaceutical calculation, and various pharmaceutical dosage forms, including solution, drops, suspension, emulsion, solid preparation (powders, pill, pastilles, troches, lozenges), semisolids, parenteral preparation

Assessment: Written exam, laboratory practice and exam

Media: Handout, Slides, Board, Video

Literature:  Thompson, JE, A Practical Guide to Contemporary Pharmacy Practice, 2^nd ed., Lippincott Williams & Wilkins, Baltimore, 2004.

ISBN-10: 0781741777

 Winfield, AJ, Richards, R M E (eds.), Pharmaceutical Practice, 3^rd ed., Churchill-Livingtone, London, 2004. ISBN-10: 044307206X

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 The Art, Science, and Technology of Pharmaceutical Compounding, 2^nd Edition. Loyd V Allen, Jr., American Pharmaceutical Association, Washington, DC, 2002. ISBN-10: 1582120862

Degree Programme: Undergraduate Programme in Clinical and Community Pharmacy Title of Module: Basic Pharmaceutical Compounding and Manufacturing

Abbreviation: BPCM

Title of Class: FK2132 Basic Physical Pharmacy

Semester: 3

Lecturer:  Dr. Jessie S. Pamudji

 Dr. Rachmat Mauludin

Language: Indonesia

Class Type / Hours: Lecture / 3 h per week Workload: Study time in class: 48 h

Study time at home: 96 h

Credits: 4.17 ECTS

Study Goals / Skills: Knowledge:

 Identify phsycochemical properties and data of drugs and excipients in pharmaceutical dosage form.

 Describe method to increase the solubility, physical and chemical stability of drugs.

Skill:

 Use phsycochemical properties and data of drugs and excipients in drug formulation and dosage form.

 Demonstrate method in improving phsycochemical properties of drugs.

Competence:

 Determine physicochemical improvement of drugs in pharmaceutical formulation.

Content: Introduction, solubility and solution, kinetics and drugs stability, diffusion, disolution and drug release, interfacial phenomena, rheology, micromiretics, colloidal and coarse disperse system (suspension and emulsion)

Assessment: Written exam

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Media: Handout, Slides, Board, Laboratory Manual

Literature:  Sinko, P.J., Martin’s Physical Pharmacy and Pharmaceuticals Sciences, 6^thed, Lippincott Williams & Wilkins, Baltimore, 2011

 Cartensen, J.T., Pharmaceutical preformulation , CRC Press, Boca Raton, 1998

 Wells, J.I., Pharmaceutical preformulation, the physicochemical properties of drug substances, Ellis Horwood Limited, Chichester, 1988.

 Aulton ,M.E., Aulton's Pharmaceutics: the design and manufacture of medicines, 4^th Ed, Churchill Livingstone, Edinburg, 2013,

Title of Module: Basic Pharmaceutical Compounding and Manufacturing

Abbreviation: BPCM

Title of Class: FK2231 Basic of Pharmaceutical Dosage Forms Technology

Semester: 4

Lecturer:  Dr. Sasanti Tarini Darijanto

 Dr. Heni Rachmawati

 Dr. Saleh Wikarsa

Language: Indonesian

Class Type / Hours: Lecture / 3 h per week Workload: Study time in class: 48 h

Study time at home: 96 h

Credits: 4.17 ECTS

Study Goals: Knowledge:

Describe the various pharmaceutical dosage forms and distinguish them based on formula, administration route, and delivery system.

Skill:

Use the knowledge about pharmaceutical dosage form to manage the quality of drug dosage forms.

Competence:

Determine the appropriate dosage form and administration route to achieve theurapeutic goal.

Content: Introduction to drug delivery system; biopharmaceutic and

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pharmacokinetic considerations in drug development; administration routes and drug dosage forms; preformulation study; formulation, preparation method/technique, packaging, specifications and quality control of drug products; stability study of pharmaceutical dosage forms

Assessment: Mid and final exam, assignment

Media: Handout, Slides, Board

Literature:  Alfonso R. Gennaro (Ed.), Remington: The Science and Practice of Pharmacy, 20t ed., Lippincott William & Wilkins, Baltimore, 2000.

 Aulton. M.E., Pharmaceutics, The Science of Dosage Form Design , Churchil Livingstone, Edinburgh, 1988.

 Lachman,L., et al, The Theory and Practice of Industrial Pharmacy, Marcel Dekker Inc., New York, Bassel, 3th ed, 1986.

 Ansel, H.C., et al., Pharmaceutical Dosage Forms and Drug Delivery System, 5th ed , Lea & Febiger, Philadelphia, 1990.

 Farmakope Indonesia edisi IV, Departemen Kesehatan RI., 1995.

 Sumie Yoshioka and Valentino J. Stella, Stability of drugs and dosage forms, Kluwer Academic Publisher, London, 2002.