Supplemental Digital Content 1:GOLIGHER’S CLASSIFICATION Grade Degree of prolapse
I No prolapse
II Prolapse on defecation with spontaneous reduction III Prolapse on defecation requiring manual reduction IV Prolapse and irreducible
Supplemental Digital Content 2:SODERGREN HEMORRHOID SYMPTOM SEVERITY SCORING SYSTEM
1) have you considered or excluded another pathology? Yes/No 2) Does the patient suffer from rectal bleeding? Yes/No
Only proceed with questionnaire if YES is the answer to both questions
Please answer the following questions relating to symptoms, at or around your anus.
Symptoms Points score How severe are your symptoms
of itching or irritation?
(circle number from 1-5)
0 1 2 3 4 5
No symptoms
Mild / do not really bother me Moderately bothersome Severe
0 0 0 0 4 4 How severe are your symptoms
of pain or discomfort at rest?
(circle number from 1-5)
0 1 2 3 4 5
No symptoms
Mild / do not really bother m Moderately bothersome Severe
0 0 0 3 3 3 How severe are your symptoms
of pain or discomfort on opening your bowels?
(circle number from 1-5)
0 1 2 3 4 5
No symptoms
Mild / do not really bother me Moderately bothersome Severe
0 0 0 0 3 3 How often do you feel that you
might have a lump at your anus (prolapse)?
0 1 2 3 4
Never
Less than once a month More than once a month More than once a week Every day
0 0 0 0 4
Final score (0 – 14 points)
Supplemental Digital Content 3:HEMORRHOIDAL DISEASE BLEEDING GRADE
Type of bleeding Grade
No rectal bleeding 0
Bleeding when passing stool less than once a week 1
Bleeding when passing stool 1–6 days per week 2
Bleeding when passing stool every day or with hemodynamic/laboratorial changes
(anemia, with or without transfusion need, signs of hypovolemia) 3
Participants not achieving therapeutic success
n=13Polidocanol foam group
n=4 Rubber band ligation group
n=9
Therapeutic failure
n=4
Moderate/Severe complications
n=0
Therapeutic failure
n=7
Moderate/Severe complications
n=2
Rubber band ligation
n=3
Hemorrhoidal Artery Ligation
n=1
Polidocanol foam sclerotherapy
n=7
Milligan-Morgan hemorrhoidectomy
n=2
SUPPLEMENTAL DIGITAL CONTENT 5:RECURRENCE COMPARISON BETWEEN TREATMENT GROUPS
All
Polidocanol foam
Rubber band
ligation p Recurrence 3 months (n=107) (n=56) (n=51)
0.184 None: n (%) 104 (97.2) 56 (100.0) 48 (94.1)
Severe: n (%) 2 (1.87) 0 (0.00) 2 (3.92) Deceased: n (%) 1 (0.93) 0 (0.00) 1 (1.96) Recurrence 6 months (n=104) (n=56) (n=48)
0.088 None: n (%) 100 (96.2) 56 (100.0) 44 (91.7)
Mild: n (%) 2 (1.92) 0 (0.00) 2 (4.17) Severe: n (%) 2 (1.92) 0 (0.00) 2 (4.17) Recurrence 9 months (n=100) (n=56) (n=44)
0.357 None: n (%) 88 (88.0) 51 (91.1) 37 (84.1)
Mild: n (%) 10 (10.0) 4 (7.14) 6 (13.6) Severe: n (%) 1 (1.00) 0 (0.00) 1 (2.27) Deceased: n (%) 1 (1.00) 1 (1.79) 0 (0.00) Recurrence 12 months (n=88) (n=51) (n=37)
0.123 None: n (%) 75 (85.2) 46 (90.2) 29 (78.4)
Mild: n (%) 13 (14.8) 5 (9.80) 8 (21.6)
Tests used to compare variables between groups: Chi-square test (Recurrence).
