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Supplementary Figure 1: Output from the Minitab analysis of the variance. Volume of the residua is reported on the vertical axis in ml for each individual. The three different numbers on the horizontal axis indicate the 3

different measurement systems (1- Omega; 2- Artec; 3- Circumferential measurements).

Supplementary Figure 2: Output from the Minitab analysis of the variance. Volume of the residua is reported on the vertical axis in ml for each individual. The three different numbers on the horizontal axis indicate the 3

different measurement systems (1- Omega; 2- Artec; 3- Circumferential measurements).

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Supplementary Figure 3: Bland-Altman of pairwise difference in volume measures for the Omega 3D scanner (left) and the Artec Eva scanner (right) vs the circumferential measurements. Each dot represents the average of

the 9 measurements ± the standard deviation for each of the 10 participants.

Supplementary Figure 4: Modified Bland-Altman plots displaying the error of CSAs measured with the circumferential method expressed as a percentage (%) of error for inter and intra-reliability. Each sample represents the error calculated for each data set collected. The different colours and shapes represent the CSA

errors calculated at the different section levels (0, 25, 50, and 75%).

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Supplementary Figure 5: Scan surface deviation plots for one example participant: the scales on the left show the deviation in mm of the two compared shapes. The transtibial residuum is represented in 4 different views.

The deviation plots have been obtained using the Artec Studio software.

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Supplementary Table 1: Relative Typical Error of Measurements (TEMs), in % for the Cross Sectional Areas (CSAs) calculated at 4 different levels of the residuum, where 0% is the proximal end and 100% is the distal end (see Figure 2 for details). Circumferential Measurements (Circum.). Values in brackets represent the 95%

Confidence Limits.

Intra-rater

0% 25% 50% 75%

Omega 1.33 1.41 2.20 5.65

(1.09; 1.73) (1.15; 1.83) (1.79; 2.86) (4.52; 7.68)

Artec Eva 1.02 0.94 1.56 5.50

(0.83; 1.33) (0.77; 1.23) (1.27; 2.09) (4.37; 7.49)

Circum. 4.34 3.18 3.29 5.35

(3.60; 5.52) (2.64; 4.03) (2.73; 4.20) (4.40; 6.94) Inter-rater

0% 25% 50% 75%

Omega 2.13 2.21 4.70 10.61

(1.74; 2.78) (1.82; 2.91) (3.88; 6.15) (8.54; 14.55)

Artec Eva 1.71 1.92 2.74 7.14

(1.39; 2.26) (1.56; 2.54) (2.21; 3.63) (5.72; 9.84)

Circum. 4.71 3.91 7.21 11.32

(3.73; 6.38) (3.24; 4.96) (5.92; 9.38) (9.20; 15.21)

Supplementary Table 2: Relative Typical Error of Measurements (TEMs), in % for the Perimeters lengths (PEs) calculated at 4 different levels of the residuum, where 0% is the proximal end and 100% is the distal end (see Figure 2 for details). Circumferential Measurements (Circum.). Values in brackets represent the 95%

Confidence Limits.

Intra-rater

0% 25% 50% 75%

Omega 0.92 0.50 1.04 1.58

(0.75; 1.21) (0.41; 0.66) (0.86; 1.38) (1.27; 2.11)

Artec Eva 0.60 0.50 1.05 1.61

(0.49; 0.79) (0.41; 0.66) (0.86; 1.38) (1.31; 2.11)

Circum. 1.88 1.79 1.68 2.66

(1.55; 2.43) (1.48; 2.31) (1.39; 2.19) (2.20; 3.47) Inter-rater

0% 25% 50% 75%

Omega 1.49 1.11 1.32 3.21

(1.22; 1.94) (0.91; 1.45) (1.09; 1.75) (2.54; 4.47)

Artec Eva 1.69 0.95 1.44 2.90

(1.37; 2.23) (0.77; 1.25) (1.17; 1.90) (2.34; 3.97)

Circum. 2.70 2.00 4.03 5.37

(2.24; 3.42) (1.66; 2.54) (3.20; 5.46) (4.42; 6.97)

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