CHEM 334 Syllabus
Course Code Course Name Credits Prerequisite(S) Classification CHEM 334 Physical organic
chemistry 2 CHEM 232 Department
Requirement Course
Description Physical organic chemistry (Chem 334) focuses on relating the structure to the reactivity of Organic molecules through the electronic effects and the steric effect, the different methods of determining a reaction mechanism, interpret and suggest the mechanisms of some common organic reactions such as nucleophilic and electrophonic substitution reaction, elimination and addition reactions.
Course 334 also discusses the effects resulting from changes in substituent (electronic effects), reagents or solvents.
Class Scheduling
Classes are held 2 times/week each for 50 minutes.
Textbook 1- Guidebook to Mechanism in Organic Chemistry, peter Sykes, 6thed., Longman.
Organic Chemistry, J. McCurry, 7th ed., 2008, Belmont, C A.
Course
Coordinator Dr. Nada Y. Tashkandi Dr. Zahraa AlAmshany Dr. Mahmood Hesien Dr. Khaled Al Gamdi
Relationship
to SOs 1 2 3 4 5 6
X X X
CLOs CLO1. Identify the effect of structure on the reactivity of organic molecules through the electronic effects and the steric effect. (SO1)
CLO2. Analyze the various methods to identify mechanism of organic reactions(SO2)
CLO3. Solve organic reaction mechanism problems (SO2)
CLO4. Describe the various effects (structure, medium, Nu and LG.) on the mechanism of the reaction. (SO1)
CLO5. Interact in teamwork in different activities. (SO6)
Contents
List of Topics No. of
Weeks Electronic and Steric Effect on the reactivity 1 Hammett equation and deviation from it 2 Non kinetic methods for determining reaction mechanism. 1 Kinetic methods for determining reaction mechanism 3 Classification and determination of reaction mechanisms Classification of factors affecting the substitution reactions 2
Factor affecting SN reactions. 2
The effect of neighboring group
Internal Nucleophilic substitution reactions SNi
Allylic Nucleophilic substitution reactions SN’ 2 Electrophilic and Nucleophilic substitution reactions
Elimination Reactions. 1
