ديدج ثحب : ةقيثولا ةلاح
Subject
:Hepatoprotective Effect of Methanol Extracts of Zingiber
ةيزيلجانلا : ةقيثولا ةغل Abestract: The present work was carried out to investigate the hepatoprotective effect of ginger, chicory and their mixture against carbon tetrachloride intoxication in rats. Carbon tetrachloride treatment signifi cantly elevated the alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and gamma glutamyltransferase activities and the serum triglycerides and cholesterol concentration as compared to control group. It also increased RBCs counts and Hb concentration, total or differential leucocytes counts. However it decreased platelet counts, platelet distribution width, mean platelet volume, platelet larger cell ratio. Methanol extract of ginger (250 and 500 mg/kg) and chicory (250 and 500 mg/kg) given alone or mixed (1:1 wt/wt) signifi cantly restored the carbon tetrachloride- induced alterations in the biochemical and cellular constituents of blood. No toxic symptoms were reported in doses up to 5 g/kg. Alkaloids and/or nitrogenous bases, carbohydrates and/or glycosides, tannins, fl avonoids, saponins and unsaturated sterols and/or triterpenes are the main active constituents of their methanol extract. The hepatoprotective effect of ginger and chicory was also confi rmed by the histopathological examination of liver tissue.
: رشاانلا Indian Journal of Pharmaceutical Sciences
: دمدر 1319 - 0989
ةياناسانلا مولعلا و بادلا ةلجم : ةيرودلا مسا : دلجملا 72
: ددعلا 5 : رشانلا ةانس 1431
ـه 2010 م
نم : تاحفصلا 539
ىلإ - 576
Publisher-id: 0250-474x
ةيملع ةلاقم : ةلاقملا عوان : عقوملا ىلع ةفااضلا خيرات Thursday, April 07, 2011
Document Type: Article In Journal
Document Title: Hepatoprotective Effect of Methanol Extracts of Zingiber
Document Status : New Document
Subject : Hepatoprotective Effect of Methanol Extracts of Zingiber
Document Language : English
Abstract : The present work was carried out to investigate the hepatoprotective effect of ginger, chicory and their mixture against carbon tetrachloride intoxication in rats. Carbon tetrachloride treatment signifi cantly elevated the alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and gamma glutamyltransferase activities and the serum triglycerides and cholesterol concentration as compared to control group. It also increased RBCs counts and Hb concentration, total or differential leucocytes counts. However it decreased platelet counts, platelet distribution width, mean platelet volume, platelet larger cell ratio. Methanol extract of ginger (250 and 500 mg/kg) and chicory (250 and 500 mg/kg) given alone or mixed (1:1 wt/wt) signifi cantly restored the carbon tetrachloride- induced alterations in the biochemical and cellular constituents of blood. No toxic symptoms were reported in doses up to 5 g/kg. Alkaloids and/or nitrogenous bases, carbohydrates and/or glycosides, tannins, fl avonoids, saponins and unsaturated sterols and/or triterpenes are the main active constituents of their methanol extract. The hepatoprotective effect of ginger and chicory was also confi rmed by the histopathological examination of liver tissue.
Publisher : Indian Journal of Pharmaceutical Sciences
ISSN : 1319-0989
Journal Name : Arts and Humanities Journal
Volume : 72
Issue Number : 5
Publishing Year : 1431 AH AD2010
Pages : From 539 - To 576
publisher-id : 0250-474x
Article Type : Article
Added Date : Thursday, April 07, 2011
نوثحابلا
مسلا (يبرع) ريأخلا مسلا (يزيلجانا) ياناثلا مسلا (يبرع) ياناثلا مسلا (يزيلجانا) لولا مسلا (يبرع) لولا مسلا (يزيلجانا) ناوانعلا (يبرع) ناوانعلا يانورتكللا ديربلا ةيملعلا ةبترملا ثحابلا عوان (يزيلجانا) ريأخلا
ءاانث Thana حاتفلا دبع Abd ElFatah
ىلوأخلا ElKholy هاروتكد يسيئر ثحاب [email protected]
ةيلك
ةيكيانيلكلا ةيذغتلا مسق - ةيقيبطتلا ةيبطلا مولعلا Applied Medical Secience- clincal Nutrition Dep
تافلملا
فصولا عوانلا فلملا مسا
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