(f DINH D U O N G V A THLfC AN CHAN N U U l )
«
ANH H l / d N G CUA BO SUNG KHANG THE VAO KHAU PHAN AN CUA LON CON BU S C A VA SAU CAI S 0 A
^ Le Danh Thanh^ va Dang Thuy Nhung^' N g a y n h a n b a i b a o : 17/01/2015 - N g a y n h $ n b a i p h a n b i e n : 21/01/2015
N g a y b a i b a o d u g c c h a p n h a n d a n g : 22/01/2015
T O M T A T
Thi nghlfm dugc tien hanh tgi Cong ty TNHH Ign giong Dabaco n h 5 m danh gia a n h huong aia vi|c bo sung khang the duoi dang che'phain Ig-Guard Swine vol lieu 0,2% va Focus SW12 voi lieu 0,05%
vao kha'u phan an cua lgn con bu sira va sau cai sira. Cac thi nghi?m deu d u g c lap lai 3 ISn, Ign con bii siia (7-21 ngay tuoi) va sau cai sua (21-33 ngay tuoi) trong cac 16 DC, T N I va TN2 d u g c a n cac khau phan tuong u n g la: khong bo sung, bo sung Ig-Guard Swine va bo sung Focus SW12. Tong so Ign con theo doi trong giai doan bu sua la 150 con/16 (15 lgn me/16) va sau cai s u a la 90 con/lo. Ke't qua eho thii'y:
Bo sung cac ehe phaim Ig-Guard Swine hoac Focus SW12 co tac dung: TKL cai siVa t u o n g u n g la 5,49 va 7,5%; Idim lugng 33 ngay tuo'i tuong ling la 6,14 va 7,79%; Giam ty 1^ m a c b^nh ti2u chay tuong ung la 9,8-10,7% va 10,1-12,0%; Giam tieu ton thiic a n tuong u n g la 0,25 v a 0,21 kg/kg, giam chi phi thiic 5n tuong ling la 3.463 va 2.978 d/kg TKL so voi khong bo sung. Nen bo sung ehe p h a m Ig - Guard Swine hoac Focus SW12 vao kha'u phan an ciia Ign con tap an va sau cai sua.
Tix khoa: khang thC Ig-Swine Guard, Focus SW12, Ign con
A B S T R A C T
T h e effects of a d d i t i o n a l a n t i b o d y to d i e t s f o r s u c k l i n g a n d w e a n i n g p i g l e t s Le Danh Thanh and Dang Thuy Nhung The experiment was conducted in Dabaco Ltd Breeding Pigs Company to evaluate the effect of the antibody addition in forms of Ig-Guard Swine and Focus SW12 preparations with doses of 0.2% and 0.05%, respectively to the diets of suckling and after weaning piglets. The experiments were repeated three times, suckling piglets (7-21 days old) and after weaning (21-33 days old) in 3 groups: control, treatment 1 and treatment 2 were feeding with the diets respectively; n o additional, Ig-Guard Swine additional and Focus SW12 additional. The total piglets in each group were 150 (15 sows per lot) for suckling period and 90 for after weaning periods. The results showed that: effects of the additional Ig- Guard Swine and Focus SW12 preparations as follows: Increase weaning weights 5.49 and 7.5%, respectively, weights at 33 days old 6,14 and 7.79%, reduce the incidence of diarrhea from 9.8 to 10.7%
and from 10.1 to 12.0%, reduce FCR 0.25 and 0.21 kg and reduced feed costs 3463 and 2978 VND/kg weight gain, respectively in comparison with no supplementation. Should be supplemented Ig-Swine Guard or Focus SW12 preparations to diets of suckling and after weaning piglets.
Keywords: antibody, Ig-Swine Guard, Focus SWll, piglets
' Khoa; Chan nuoi - Nuoi trong Thuy san, Hgc vien Nong nghiep Vi^t Nam.
' Tac gia de lien h^: TS. Dang Thuy Nhung, Giang vien, Bg mon Dinh d u o n g - Thiic Sn, Khoa Chin nuoi vh Nuoi trong Thuy san, Hgc vi^n Nong nghigp Vi?t Nam, Trau Quy, Gia Lam, Ha Ngi. Di^n thogi:
(84.4) 38768273, Di dgng; 0912 058 396/0165 7269829, Fax: (84.4) 38276554, Email: [email protected]
22 KHKT Chan nuoi So 4-2015
D I N H D I / O N G V A T H l / C A N C H A N N U O I L D A T V A N D £
Lgn eon bii sua va sau cai siia vol dac diem sinh ly tieu hoa, hg thong mien djch chua hoan thien l?i phai thich ling vol dieu kien nuoi duong eo nhieu thay doi anh huong khong to't toi sinh truong va de mac benh. Vi v^y, nang eao kha nang mien dich dgc bi?t la kha nang chong l^i eae vi khuan eo hai trong duong rugt nham phong eho'ng cac benh duong tieu hoa la bien phap quan trgng dam bao eho su phat trien binh thuong eiia lgn con.
Nghien cihi su dung eac probiotic, axit hiru CO, thao dugc... trong do cac khang the dugc eoi nhu mgt trong eae giai phap hiru hi?u thay the' eho vige sii dyng khang sinh trong thiie an chan nuoi (Doyle, 2001;
Papatsiros va etv, 2014). Theo Cyparrelly va etv (1992), khang the dge h i | u IgY xua't hign trong huye't thanh sau 8 ngay, trong tiling sau 10 ngay va d^t hieu qua eao nha't trong ngay thii 15 va 20 sau khi mien dich eho ga.
Cii lOg long do trung sau khi tach protein, lipit va say kho co the thu dugc 15mg IgY 6 dg tinh khiei 93,8%. Su dung c h e p h S n nay dieu tri co higu qua bgnh tieu chay do E.coli a lgn eon theo m? (Yokoyama va etv, 1992).
Theo Li va etv (2006), eho lgn eon uong khang the IgY-Hp giam nhiem duge H.
Pylori., sir dung khang the long do trung ga lie ch^' dugc sinh tru6ng eiia Aeromonas hydrophila tiong thai gian u bgnh, giam 70%
ty I? che't va dieu tri Wioi 70-71% lgn con sau eai sua mac tieu chay. Che p h & i bgt khang the YP - 99 khang E.coU ciing voi vi khuan E.Rnl, E.Rn2 va E.Ma (mang yeu to'bam dinh F5 va F6, vo hoat bang formol) eo tac dyng dieu tri bgnh tieu chay tren lgn eon theo mg (Dang Xuan Binh va ctv, 2003). San pham
IgOne-S ehiia khang the IgY tu long do triing ga eiia Cong ty CTCBIO giiip lgn eon tang cudng siie de khang, phong bgnh tieu chay, tang ti 1? so'ng, khoi lugng lgn eon cai sua va giam ti 1? eoi ege (CTC BIO Vigt Nam, 2011).
Gan day, tren thi truong Viet Nam da xua't hign mgt so ehe' pham khang the n h | p tu nuoc ngoai va Ig-Guard Swine, Focus SW12 duge khuye'n cao co tac dung phong va chohg eae benh duong tieu hoa a Ign eon. De tai duge thuc hign nham danh gia anh huong va higu qua eiia vi$e bo sung hai logi khang the nay vao kha'u phan eua lgn eon giai d o ^ 7-33 ngay hjoi.
Z VJSLT LIEU VA PHl/ONG PHAP NGHIEN CtfU 2.1. V^t ligu nghien cmi
Vgt ligu nghien eiiu la 2 lo?i khang the:
- Ig-Guard Swine la ch^' pham do Cong ty AD bioteeh ciia Han Quo'e san xua't, thanh phan chinh la bgt tning d^e bigt va oligosaccharides co tac dyng giiip tang sinh cac vi khuan co Igi eu tni 6 duong tieu hoa nhu: Lactobadllus, Bifidobacteria... ho tig duong tieu hoa ciia Ign eon mgt each an toan.
- Focus SW12 la ehe' phei'm do Cong ty Trouw Nutrition ciia My san xua't, thanh phan chinh la IgY a dgng vi bge (nano) co tac dyng chong lai E.coli K88, K99, F41, 987P, Fy, F42, F165, 0157, Clostridium perfringens type A va C, Clostridium khac. Rotavirus, viem dg day rugt truyen nhiem va dich tieu chay 6 lgn dong thoi ehiia mgt so vi khuan CO Igi (probiotic).
Hai logi khang the tien duge bo sung vao khau phan giai dogn 7-33 ngay tuoi dung eho lgn lai giira dye PiDu voi nai YL.
::^ KHKT Chan nuoi So A - 2015
23
DINH D I / O N G V A THU'C AN CHAN NUOI 2.2. Phmmg phap nghien cmi
Thiic an h6n hgp gom 3 logi: 4000A (khong bo sung khang the), 4000A* (bo sung Ig-Guard Swine voi ty Ig 0,2%) va 4000 A** (bo sung Focus SW12 voi ty le 0,05%) chuan bi tai Cong ty Thue an Nutreco thugc tap doan Dabaco, Bac Ninh.
Gia tri dinh duong cua thiie an eho eae 16 DC, TNI va TN2 la nhu nhau, bao gom: Nang lugng trao doi 3460,87 Keal/kg; protein Iho 19%, lipit tho: 7,81%; xo tho 1,9%; Ca tong so 0,93%; P hap thu 0,6%; muoi an 0,68%; lysine 1,41%; methionine + cystine: 0,84%; threonine 0,97%, tryptophan 0,26%.
Thi nghiem theo doi anh huong ciia viee bo sung hai logi khang the neu tren doi voi lgn eon theo m? (7-21 ngay tuoi) va lgn eon sau sai sira (21-33 ngay tu6i) duge thyc hien tgi Cong ty TNHH lgn giohg Dabaco, xa Tan Qu, huyen Tien Du, tinh Bae Ninh.
- Dot v&i Ion con bii m^
Chgn 15 lgn nai lai (LY) da dugc phoi gi6'ng voi dye PiDu bat dau giai doan nuoi con (trung binh 10 lgn con/nai), dong deu ve so'lua de (3-5) va kha nang san xua't va dan eon, phan ngau nhien vao 316: DC, TNI va TN2, moi lo 5 lgn m§, Thi nghigm duge Igp lai 3 Ian voi tong so' 15 lgn mg va 150 con eho moi 16. Lgn eon bat dau tu 7 ngay tuoi tdi eai siia, 16 DC an thiic an 4000A, 16 TNI an thiie an 4000A* va TN2 an thiie an 4000A**.
- BSi vai Ian con sau cai siia
Ke't thiic giai doan bii siia, lgn con duge ehuyen len chuong eai siia. Chgn 90 lgn eon cai sira dong deu nhau ve khoi lugng dugc phan vao 3 16: DC, TNI va TN2, m6i 16 30 eon. Thi nghigm duge Igp lai 3 1 ^ , vol tong so 90 lgn con eho moi 16.
Lgn eon bii siia va sau cai siia dugc trong eae 6 chuong eo san bang nhya. Trong c^e 6 chuong co mang an, niim u6'ng nuoc ty dgng, hg thohg den suoi, lam mat va binh pha thuoc dign giai. Lgn con dugc tiem phong vaccine day dii va eham soe theo quy trinh ky thuat eiia C6ng ty. Cac lgn con bi tieu chay duge dieu tri bang Genorfcoli voi thanh phan chinh la Gentamycin, Colistin tiem vol lieu 2-3 ml/ngay.
ThM gian theo doi cdc thi nghiem: tir thang 10/2014 den thang 1/2015.
Chi tieu theo doi va phuang phap xu ly so lieu Cae ehi tieu theo doi bao gom: kh6l lugng lgn eon Iiic so sinh, 7, 14, 21 va 33 ngay tuoi;
tinh hinh sii dung thiie an, mac bgnh tieu chay trong 2 giai doan 7-21 va 21-33 ngay tu^.
Cac so" lieu dugc xii ly th6'ng ke sinh hgc va phan tich phuang sai (ANOVA) theo mo hinh thi nghigm mgt nhan to' hoan toan ngau nhien (CRD) tren Excel 2007 va Minitab 16.
3. K^T QUA VA THAO LU^N
3.1. Khoi lugng va tang khdi lugng trung binh lgn con
3.1.1. Doi vai Ian con bii sua
Kh6i lugng lgn eon liie 7 ngay tuoi eiia ca 3 13 DC, TNI va TN2 la tuong duong nhau.
Khoi lugng trung binh lgn con 6 eac ngay tuoi 7,14, 21 deu tuong duong ho|ic eao hon mgt it so voi eae so" ligu theo doi ciia Do Thi Nga va D|ing Thiiy Nhung (2013): khoi lugng lgm eon lai (LY) 7, 14 va 21 ngay tuoi tuong ling la 2,69; 4,52 va 5,55-6,48 kg/con.
N h u vay, sinh truong,ciia lgn con trong thuc nghigm nay la binh thuong.
24
KHKT Chan nu6i Sii 4-2015DINH D U ' O N G V A THLfC AN CHAN NUOI Bang 1. Khdi lugng co the va tang khdi lugng hkng ngay ciia lgn con 7-33 ngiy tuoi
DC (n = 150)' TNI (n = 150) TN2 (n = 150) X ± SE X ± SE X ± SE
2,72 ±0,05 2,73 ±0,03 4,78 ±0,12 4,67 ±0,15 6,78" ±0,05 6,88" ±0,10 294,29 ± 12,40 277,14 ± 12,40 285,71 + 11,7 315,71 ±8,78 290,00^ ± 5,88 296,43" ± 6,36 Khoi lugng 7 ngay tuoi (kg/con) 2,71 ± 0,03
Khoi lugng 14 ngay tuoi (kg/con) 4,36 ± 0,10 Khcft lugng 21 ngay tuoi (kg/con) 6,40" ± 0,11 ngay tuoi
(n = 150) ^ ^ 8 ^ ^ ' 'w^ng ^-14 ngay tuoi (g/ngay) 235,71 ± 10,30 Tang khoi lugng 14-21 ngay tuoi (g/ngay) 291,43 ± 7,37 Tang khoi lugng 7-21ngay tuoi (g/ngay) 263,57^ ± 8,84 21 33 ^ ° ' li^Png 21 ngay tuoi (kg/con) 6,57 ± 0,02 ngay tuoi Khoi lugng 33 ngay tuoi (kg/con) 8,47'' ± 0,06
(n = 90)
Tang kh6i lugng 21-33 ngay tuoi (g/ngay) 172,73''± 6,31
6,58+0,02 6,56a ±0,02 8,99^ + 0,03 9,13= ±0,11 219,09" ± 4,63 233,64" ± 7,89 Ghi chu: Cdc gia tri trung hinh trong cung mot hang mang cdc chU cdi khdc nhau Id sai khdc nhau co y
nghia thdng ki (P<0,05).
Sau 1 tuan tap an, khoi lugng lgn eon liie 14 ngay tuoi ciia cac 16 TNI va TN2 deu eao han 16 DC, nhung sai khac nay kh6ng co y nghia thohg ke. Da xua't hign sai khae co y nghia tho'ng ke ve kho'i lugng lgn eon liie 21 ngay tuoi giua 16 DC so vdi eae 16 TNI va TN2, trong do chenh Igch giiia 16 TNI va DC la 0,38 kg/eon hoac 5,49%; giira TN2 va 13 DC la 0,48 kg/eon hoac 7,5%. Mae du, khoi lugng trung binh lgn eon 21 ngay tuoi eua 16 TN2 eao hon so voi TNI, nhung sai khae giiia 2 16 nay la kh6ng co y nghia th6ng ke (P>0,05).
Miie tang kh6i lugng tiung binh hang ngay ciia lgn con tiong cae 16 DC va TN dat duge deu eao hon so voi cae s6' lieu theo doi duge eua T6n That Son va etv (2010): tang truong tuyet doi eua lgn con lai (LY) tu so sinh deii 21 ngay tuoi vai kha'u phan tap an CO bo sung 1,6% lysine la 231,43 g/con/ngay, cung nhu ciia Varley va ctv (1995): sinh truong tuygt doi ciia lgn con tir so sinh tai 21 ngay tuoi d vao miie 180-240 g/eon/ngay.
Cae so sanh ve tang kh6i lugng trung binh hang ngay cung eho ke't qua tuong ty nhu doi voi kh6i lirgng tiung binh: tang kh6i lugng trung binh hang ngay tCr 14 den 21 ngay tuoi dat eao nha't 6 hai 16 TNI va TN2, eao hon ro r|t (P<0,05) so vai 16 DC. Chenh Igeh giiia TNI vol DC la 26,43 g/con/ngay hoac 10,03% , giua TN2 va DC la 32,86 g/con/ngay hoUc 12,47%. Tang kh6i lugng trung binh hang ngay ciia 16 TN2 cao hon so voi TNI, nhung sai khae giiia 2 16 nay la kh6ng co y nghia tii6'ng ke (P>0,05).
Nhu v?y, bo' sung ehe' phain co ehiia khang the vao khau phan an chd lgn eon da CO anh huong tich eye d6i vdi sinh truong eiia lgn eon trong thoi ky bii sua. Nguyen nhan la do Ig-Guard Swine hoae Focus SW12 CO m^t trong dudng tieu hoa eiia lgn eon da lie che'va tieu diet cae vi sinh v^t ed hgi, tang them eac vi sinh vat cd Igi trong duong tieu hda, giiip lgn eon tieu hoa va ha'p thu thiie an t6't hon, nho do cai thien duge kha nang sinh truong ciia lgn eon.
vuifT Phan niiAi Cn & - 9fl1i; 25
DINH DU'ONG VA THl/C AN CHAN NUOI
3.1.2. Dot v6i IQH con sau cai siia So ligu bang 1 eho thay liic bat dau thue nghiem giai doqin sau cai siia (21-33 ngay tiioi), ea 316 lgn DC, TNI va TN2 deu ed khoi lugng trung binh tuong duong iJiau, sai khac giiia 3 16 nay la khdng ed y nghia thdng ke (P>0,05). T?i 33 ngay tuoi, khoi lugng trung binh eua lgn con d Id TN2 dat eao nha't, tie'p theo la TNI va tha'p nhat la DC Chenh lech khdi lugng giua lgn con trong TN2 va DC la 0,52 kg/con hoac 6,14%; giira TN2 va DC la 0,66 kg/con hoge 7,79%. Khac biet giira TNI, TN2 so vdi DC la ed y nghia thong ke (P<0,05), khae biet giua hai Id TNI va TN2 la khong ed y nghia thong ke (P>0,05).
Tang khdi lugng trung bmh tu 21 tdi 33 ngay tuoi dat cao nhat la lgn con tiong 16 TN2, tie'p do la TNI va thap nhat la 16 DC. Chenh l|ch ve TBCL trung binh giiia TN2 va DC la 46,36 g/eon/ngay hoac 26,84%; giiia TN2 va DC la 60,91 g/coii/ngay hoae 35,26%. Khac bi^t giiia TNI, TN2 so vdi DC la ed y nghia thong ke (P<0,05), khae bi^t giira hai 16 TNI va TN2 la khdng cd y nghia thd'ng ke (P>0,05).
Ro rang la vigc bd sung khang the trong eae ehe' pham Ig-Guard Swine hoae Focus SW12 ciing da gop phan tang cudng kha nang sinh truong ciia Ign eon giai doan sau eai siia.
3.2. Tinh hinh mic bgnh tieu chay lgn con
Bdng 2. Tinh hinh mac bgnh tieu chay cCia lgn con Giai do^n Chi tieu theo doi
7 - 2 1 ^ ^°^ *'^" chay (con) ngay tuoi Ty 1§ ti^u chay (%)
( n = 1 5 0 ) g - ' j ^ g ^ y jJig-^j tj-i ^ n g ^ y j
2 1 - 3 3 So con tieu chay (con) ngay tuoi Ty I? tieu chay (%)
(n = 90) So'ngay dieu tri (ngay) 35
23,33 2,5-3 32
35,56 3
19
12,67 1,5-2 23
25,56 2
17
11,33 1,5-2 22
24,44 2
Bang 2 eho tha'y, trong thoi gian bii siia, tong sd'lgn eon mac benh tieu chay eiia eac Id DC, TNI va TN2 tuong ling la 35,19 va 17 ca thC chiem ty 1? so vdi toan dan la 23,33; 12,67 va 11,33%. Nhu vay, bo sung khang the dudi dang ehe' pham Ig-Guard Swine hoae Focus SW12 da giam duge ty le mac b?nh tieu chay 10,7 hoae 12,0% so vdi khdng bo sung. D6i vdi cae lgn con dugc an khau phan cd bo sung khang the (TNI va TN2), khi mac benh tieu chay ed thoi gian dieu tri riit ngan hon khoang 1 ngay so vdi lgn eon khong duge an
khau phan cd bd' sung khang the. Dieu nay lien quan toi vige giam ehi phi thu6'c men va nhan e6ng eham sdc, hg ly,
Tuong ty nhu vgy, trong giai d o ^ sau cai sua, s6' lgn con mac bgnh tieu chay eiia cae 16 DC, TNI va TN2 tuong ling la 32,23 va 22 ea thC chie'm ty Ig so vdi toan dan la 35,56;
25,56 va 24,44%. Cac ty ig mac tieu chay nay cao hon so vdi giai doan bii sua mg la do lgn con sau cai sira phai so'ng dgc lap vdi moi trudng mdi co nhieu thay doi va chiu tac dgng bdi nhieu stress. Vige bd sung khang
26
KHKT Chan nuoi So 4 - Z 0 1 5DINH DU'ONG VA THU'C AN CHAN NU6l the dudi dang ehe' pham Ig-Guard Swine
hoae Focus SW12 trong giai doan nay ciing da giam duge ty le mac benh tieu ehay 9,8 hoae 10,9% so vdi khdng bd sung. Bd sung khang the ciing lam giam bot duge thoi gian dieu tri, do vay cung giam duge ehi phi thu6'e va nhan edng.
Hieu qua han ehe' tieu chay neu tien tuong ty nhu eac thii nghiem ddS vdi san pham IgOne-S ehiia khang the IgY tu long do
tining ga eiia Cty CTCBIO (CTC BIO Vigt Nam, 2011).
3.3. Thu nh^n, tieu tdn va chi phi thiic an Lugng thiic an thu nhgn hang ngay eiia lgn con tu 7-21 ngay tuoi (g/ngay) ciia 3 16 thi nghigm la khac nhau kh6ng ed y nghia thd'ng ke (P>0,05), eao nhat d 16 DC: 20,48, 16 TNI:
16,67 va TN2 la 18,81 g/ngay. Sy sai khae nay kh6ng ed y nghia thong ke (P>0,05).
Bang 3. Thu n h ^ , tieu ton va chi phi thuc an DC X ±SE
TNI X ±SE
TN2 X ±SE 7-21 ngay tuoi (n = 15) Thiic an thu nhgn (g/ngay) 20,48±0,96 16,67±1,26 18,ei±l,33
21-33 ngay tuoi (n = 3)
Thiic an thu nhan (g/ngay) 227,58" ± 8,30 233,30" ± 8,30 259,60" ±7,67 Tieu ton thiic an (kg TA/kg TKL) 1,32" ± 0,002 1,06''± 0,108 1,11" ± 0,049 Gia thiic an (dong/kg) 16.740 17.460 17.170 Chi phi tliuc an (dong/kg TKL) 22.056 18.592 19.078 Nguyen Van Phii (2008) eho bie't lugng
thiic an thu n h | n hang ngay trung binh eiia Ign con giai dogn 7-21 ngay la 15,0-16,30 g/ngay. Theo Tdn That Son va etv (2010), lugng thiie an thu nhan hang ngay lgn con 7- 21 ngay tuoi la 31,9-32,5 g/ngay. Nhu vay, lugng thiie an thu n h | n cua lgn con bii siia trong thue nghiem nay d miie trung gian so vdi 2 theo doi tren.
Lugng thiic an thu nhan hang ngay eiia lgn con giai doan tir 21 - 33 ngay tuoi cao nha't d Id TN2: 259,60 g/eon/ngay; sau do la TNI: 233,30 g/ngay va thap nha't d 16 DC:
227,58 g/eon/ngay. Tuy nhien, sai khae giiia 3 16 la kh6ng ed y nghia thong ke (P>0,05).
Tieu td'n thiic an eiia eac 16 DC, TNI va TN2 Ian lugt la 1,32; 1,06 va 1,11 kg tiiiie an/kg TBCL. Chenh Igeh giira TNI va DC la
0,25 kg thiie an/kg TKL, chenh leeh giua TN2 va DC la 0,21 kg thiie an/kg TKL. Sai khac giua TNI va TN2 so vdi DC la cd y nghia thdng ke (P<0,05), giiia hai 16 TN la khdng cd y nghia thong ke (P>0,05).
Tgi thoi diem thi nghiem, gia thanh 1 kg Ig-Guard Swine la 360.000 dong/kg va Focus SW12 la 860.000 dong/kg. Sii dyng hai ehe pham nay bo sung vao thiie an vol lieu lugng Ig-Guard Swine la 0,2% va Focus SW12 la 0,05% kh6j lugng thiie an da lam tang gia thanh thiic an so vdi. khdng bo sung. Tuy nhien, do tieu td'n thiie an eho mgt kg TKL eiia Id DC eao hon so vdi Id TNI va TN2 nen ehi phi thiic an cua Id DC la eao nha't: 22.056 d/kg TKL, hai 16 TNI va TN2 ed miic Ian lugt la: 18.592 va 19.078 d/kg TKL. Chenh Igeh giira hai 16 TNI va TN2 so vdi DC tuong ling la 3463 va 2978 d/kg TKL.
KHKT Rhan nuoi Sa A - 2Q15 27
DINH DU'ONG VA THU'C AN CHAN NUOI
4. KET LUAN
Tu eae ke't qua thu duge nhiing anh hudng sau day cua viee bd sung khang the dudi hai d^ng san pham la Ig Guard Swine vdi lieu 0,2% hoac Focus SW12 vdi lieu 0,05%
vao khau phan lgn eon bii siia (7-21 ngay tuoi) va sau cai siia (21-33 ngay tuoi):
- Tang cudng kha nang sinh trudng lgn con bii sira va sau eai sua: Bd sung Ig - Guard Swme va Focus SW12 TKL eai siia 21 ngay tuoi tuong ling la 5,49 va 7,5%, TKL liic 33 ngay tuoi tuong ling la 6,14 va 7,79% so vdi khdng bd sung.
- Giam ty le mac bgnh tieu chay: Bd sung Ig - Guard Swine va Focus SW12 giam ty Ig tieu chay tuong ling la 9,8-10,7% va 10,1- 12,0% so vdi khong bd sung.
- Giam tieu t6'n va chi phi thiie an: Bd sung Ig - Guard Swine va Focus SW12 giam tieu t6'n thiie an tuong ling la 0,25 va 0,21 kg thiie an/kg TKL, giam chi phi thiie an 3.463 va 2.978 d/kg TKL so vdi khdng bo sung.
- Nen bd sung them ehe'pham Ig - Guard Swine hoge Focus SW12 vao khau phan an cua Ign eon t?p an va sau eai siia nhung trong thi nghiem eiia chiing tdi bd sung 0,05% Focus SW12 eho ke't qua tot hon.
TAI LI$U THAM KHAO
1. Dang Xuan Binh, Le Van Tao va Tran Thi H ^ h (2003), Nghien ciiu ehe tao bot khang the long do tning ga (YP-99) va hi^u qua dieu tri tieu chay do E.coli 6 Ign con theo m^. Bao cao khoa hgc Chan nuoi Thii y 2003 - 2004, tr. 219-323.
2. CTC BlOVi^t Nam (2001), Phong tieu chay hi^u q u i tren heo con voi khang th^ IgY cua IgOne-S, http://www,heo.com.vn/?x/=newsdetail&n=3395
&/c/=25&/g/=14&/6/5/2011/phong-tieu-chay-hieu- qua-tren-heo-con-voi-khang-the-igy-cua-igone_s- -pr&-l 01-vent-scour-in-pi glet-by-igy-of- igone_s,html.Truy cap ngay 10/6/2013.
3. Doyle M.E. (2001), Altematives to Antibiotic Use for Growth Promotion in Animal Husbandry. FRl BRIEFINGS, pp. 1-17
4 Do Thi Nga va Dang Thuy Nhung (2013). Bo sung chS' pham Bacillus enzyme (Probiotic) eho Ion con lai Landrace x Yorkshire tu tap an dl'n 56 ngay tuoi.'Tap chi Khoa hgc cong ngh§ chan nuoi, 4:10-16.
5. Li X.L., Shuai J.B and Fang W.H. (2006), Protection of adjuvant systems to obtam a cost- effective production of high levels of specific immunoglobulins from hen egg yolk, J. Zhejiang.
Univ. Sci., 7:922-928.
6 O'Farrelly C , Branton D and Wanke C A . (1992).
Oral ingestion of egg yolk immunoglobulin from hens immunized with an enterotoxigenic Escherichia coli strain prevents diarhea in rabbits challenged with the same strain. Infect Immun,, 60:2593-2597.
7. Papatsiros V., Tassis P., Tzika E., Papaioannou D., Petridou E., Alexopoulos C and Kyriakis S.C. (2014), Effect of benzoic acid and combination of benzoic acid with a probiotic containing Bacillus Cereus var. toyoi in weaned pig nutrition, Polish journal of veterinary sciences, 14(1): 117-125.
8. Nguyin Van Phii (2008). Anh huong cua vi^c bo sung ch&' pham Greencab (Calciumbutyrate) trong khau ph&i ciia lgn con giong ngo^i tit 7-60 ngay tura tai Xi nghiep 8^°^S S^ sue gia cam ThuSn Thanh, BIC Ninh, Luan van Thae sT nong nghiep, ehuyen nganh Chan nuoi, Truong DH Nong nghiep Ha Npi.
9. Ton That Son, Nguyen Thi Mai va Nguyen The Tuong (2010), Anh huong cua miic Lysine trong thiic an deh kha nang sinh truang ciia Ion con lai (Landrace va Yorkshire) tir 7 - 28 ngay tuoi, T?p chi Khoa hgc va Ph^t trien, truong Dai hgc Nong nghiep Ha Ngi, 8(1): 90-97.
10. Varley M.A., Verstegen M.WA. and Close W.H.
(1995), The envirorunental and the growing pigs.
In: Principles of Pig, pp. 333-353.
11. Yokoyama H., Peralla R.C., Diaz R., Sendo S., Ikemori Y. a n d Kodama Y. (1992), Passive protective effect of chicken egg yolk immunoglobulins against Experimental Enterotoxigenic Escherichia coli infection in Neonatal piglets. Infection and immunity. 3; 998-1007.
