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MOLECULAR ANALYSIS OF INDONESIAN LCA PATIENTS AND IN VITRO SPLICE CORRECTION FOR CEP290-ASSOCIATED LCA - Diponegoro University | Institutional Repository (UNDIP-IR)

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Figure  14.  AIPL1  protein  domain  structures.  (Adapted  from:  den  Hollander,  et  al.)  AIPL1  is  a  44  kDa  protein whixh is interacting with NUB, NEDD8 Ultimate Buster 1 (NUB1) protein

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The diagnostic study performed to investigate the molecular genetic characteristic of Indonesian LCA.. patients, while the functional study accomplished to optimize the use of AON