BAB V. KESIMPULAN DAN SARAN
B. Saran
1. Perlu dilakukan optimasi konsentrasi surfaktan Tween 80 dan kosurfaktan propilen glikol sehingga menghasilkan nanokrim KAD yang stabil.
2. Perlu dilakukan optimasi kecepatan mixer dan waktu stirring untuk mendapatkan ukuran droplet yang lebih kecil.
3. Perlu dilakukan uji iritasi sediaan nanokrim KAD.
4. Perlu dilakukan pengujian penetrasi nanokrim KAD ke dalam kulit.
5. Perlu dilakukan uji in vivo dan in vitro terkait dengan khasiat nanokrim sebagai antioksidan.
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LAMPIRAN
Lampiran 1. Certificate of Analysis Kojic Acid Dipalmitate (KAD)
Lampiran 2. Data Perhitungan HLB
Lampiran 3. Data Pengujian Organoleptis Nanokrim KAD Nama
Sampel
Pengamatan
Warna Bau Konsistensi Pemisahan Fase
R1 Putih
kekuningan Bau kelapa Kental Tidak ada
R2 Putih
kekuningan Bau kelapa Kental Tidak ada
R3 Putih
kekuningan Bau kelapa Kental Tidak ada
Lampiran 4. Data Pengujian Homogenitas, pH, Tipe Emulsi, Daya Sebar, Daya Lekat, dan Viskositas Nanokrim KAD
Nama
Lampiran 5. Data Pengujian Viskositas R1
R2
R3
Lampiran 6. Data Pengujian Ukuran Droplet dan perhitungannya
Diameter (nm) Frekuensi Kumulatif
171,25 54,350 54,350
193,48 45,650 100,000
Perhitungan Diameter Rata-Rata Droplet
Lampiran 7. Perhitungan % Polydispersity (% Pd)
% Pd = (Polydispersity index)1/2 x 100%
= (0,132)1/2 x 100%
= 36,33%
Lampiran 8. Data Perhitungan Rasio Pemisahan Fase Nama
Rasio pemisahan fase (R2) = 2,9 𝑐𝑚
4,3 𝑐𝑚= 0,8 Rasio pemisahan fase (R3) = 3,9 𝑐𝑚
4,2 𝑐𝑚= 0,9 Rata-rata ± SD = 0,8 ± 0,1.
Lampiran 9. Dokumentasi
Nanokrim KAD Uji Homogenitas R1
Uji Homogenitas R2 Uji Homogenitas R3
Uji Tipe Krim pada Minyak Uji Tipe Krim pada Akuades
Uji Daya Sebar R1 Uji Daya Sebar R2
Uji Daya Sebar R3 Uji stabilitas minggu ke 2
Uji stabilitas minggu ke 3 Uji stabilitas minggu ke 4
Neraca analitik
Neraca analitik
Mixer
Climatic chamber
Rheometer
pH meter
Horiba SZ-100
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BIOGRAFI PENULIS
Agnesia Brilianti Kananlua dilahirkan pada tanggal 5 Agustus 1994 di Bengkulu. Putri dari pasangan Paulus Sulluk Kananlua dan Pratiwi Nugraheni ini memiliki satu orang saudara kandung laki-laki bernama Ignasius Abdi Kusuma Kananlua. Penulis telah menempuh pendidikan di TK Sint Carolus Bengkulu pada tahun 1999 sampai tahun 2000, SD Sint Carolus Bengkulu pada tahun 2000 hingga tahun 2006, SMP Sint Carolus Bengkulu pada tahun 2006 hingga tahun 2009, SMA Stella Duce I Yogyakarta pada tahun 2009-2012, dan Universitas Sanata Dharma pada tahun 2012 hingga tahun 2015. Selama mengikuti kuliah di Fakultas Farmasi Universitas Sanata Dharma, penulis pernah bergabung dalam organisasi Jaringan Mahasiswa Kesehatan Indonesia (JMKI) dan dipercaya menjadi wakil komisaris internal periode 2013-2014. Melalui organisasi ini, penulis berkesempatan mewakili Komisariat Universitas Sanata Dharma dalam Rapat Kerja Nasional (RAKERNAS) VI JMKI pada tahun 2014. Penulis pernah mengikuti beberapa kepanitiaan acara, antara lain acara donor darah JMKI sebagai divisi acara, malam keakraban (makrab) JMKI sebagai bendahara, dan Tiga Hari Temu Akrab Farmasi (Titrasi) 2013 sebagai divisi P3K. Penulis juga pernah mengikuti Program Kreativitas Mahasiswa bidang kewirausahaan (PKM-K) 2014 berjudul Mollusca Crispy Sebagai Camilan Sumber Protein dan Peningkat Kecerdasan Otak dan lolos didanai dikti.