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Saran

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BAB V SIMPULAN DAN SARAN

5.2. Saran

Dari hasil penelitian yang didapat, maka muncul beberapa saran dari peneliti, yaitu :

1. Perlu dilakukan pemeriksaan histokimia Giemsa ataupun imunohistokimia untuk mendeteksi keberadaan bakteri H. pylori yang merupakan salah satu indikator sebagai faktor prognosis.

2. Diharapkan pada pelaporan histopatologi dapat memberikan kerangka yang konsisten untuk pelaporan histologi rutin pada kasus gastritis dengan menggunakan klasifikasi Sydney system dan staging OLGA system sehingga klinisi dapat menegakkan diagnosis dengan lebih rinci lagi agar dapat memberikan pengobatan dan pencegahan secara dini apabila terdapat tanda-tanda lesi prekanker.

3. Diharapkan pada dokter klinisi agar memberikan informasi klinis yang jelas seperti mengenai lama menderita penyakit gastritis dan obat-obatan yang sudah diberikan untuk pengobatan karena berpengaruh terhadap gambaran histopatologi gastritis kronis.

4. Diharapkan agar dokter klinisi dapat memberikan sampel jaringan biopsi dengan lima pengambilan lokasi biopsi yang sudah ditentukan (kurvatura mayor antrum distal, kurvatura minor antrum distal, kurvatura minor incisura angularis, dinding anterior corpus proksimal, dan dinding posterior corpus proksimal) agar patolog dapat memenuhi kriteria penilaian histomorfologi gastritis kronis berdasarkan OLGA System.

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68

Inflammasi Kronik Aktifitas PMN Atrofi Kelenjar Metaplasia Intestinal H. pylori Inflammasi Kronik Aktifitas PMN Atrofi Kelenjar Metaplasia Intestinal H. pylori

1 H/19/013 Benny Surbakti 49 Karo 1 0 0 0 0 1 0 0 0 0 Gastritis chemical

14 H/17/028 Andri Hatriyanto 43 Minang 1 0 0 0 0 1 0 0 0 0 Gastritis chemical 17 H/17/193 Windy Seprianto

Purba 28 Batak 1 0 0 0 0 1 0 0 0 0 Gastritis chemical

/ gastropathy 0

18 H/17/226 Suratik 59 Jawa 1 0 0 0 0 1 0 0 0 0 Gastritis chemical

/ gastropathy 0 19 H/16/001 Ahmad Dahruddin

Siregar 56 Mandailing 1 0 0 0 0 1 0 0 0 0 Gastritis chemical

70

48 H/15/237 Purnama Sari

72

84 H/14/297 Rentina Nainggolan 51 Batak 1 0 0 0 0 1 0 0 0 0 Gastritis chemical

74

101 H/12/132 Warsiyem 58 Jawa 2 0 0 0 0 2 0 0 0 0 Gastritis chemical

/ gastropathy 0

102 H/12/144 Sumarsono 54 Jawa 3 1 1 0 0 2 0 0 0 0 Gastritis

Limfositik 1

103 H/12/180 Tigor Nababan 62 Batak 2 0 0 1 0 1 0 0 0 0 Gastritis Atrofi 0

104 H/12/339 D. Sinaga 70 Batak 2 0 0 0 0 2 0 0 0 0 Gastritis chemical

/ gastropathy 0

105 H/13/340 Jiman Berutu 65 Batak 2 0 1 0 0 2 0 1 0 0 Gastritis Atrofi 1

106 H/11/005 Junaidi 39 Aceh 2 0 0 0 0 2 0 0 0 0 Gastritis chemical

/ gastropathy 0

107 H/11/009 Afrizal 48 Melayu 2 0 1 0 0 1 0 0 0 0 Gastritis chemical

/ gastropathy 1

108 H/11/069 Nuraidah 52 Jawa 2 0 1 0 0 2 0 0 0 0 Gastritis Atrofi 1

109 H/11/098 Lim Bie Eng 75 China 1 0 0 1 0 1 0 0 1 0 Gastritis chemical

/ gastropathy 0

110 H/11/145 Samin Siregar 51 Mandailing 2 0 0 0 0 0 1 0 0 0 Gastritis Kronis

aktif 0

111 H/11/163 M. Haris 31 Simalungun 1 0 1 0 0 1 0 0 0 0 gastritis Kronis

aktif 1

112 H/11/218 Erwan Arbie 61 Minang 1 0 1 0 0 0 1 0 1 0 Gastritis Atrofi 1

113 H/11/250 Harjono Saleh 34 Jawa 1 0 0 1 0 1 0 0 0 0 Gastritis Atrofi 0

114 H/11/251 Sukardi 44 Jawa 1 0 1 0 0 1 0 0 0 0 Gastritis Atrofi 1

LAMPIRAN 2.

GAMBARAN MIKROSKOPIS SAMPEL FOTO MAKROSKOPIS

FOTO MIKROSKOPIS

Gambar Mikroskopis gaster. A. Antrum. B. Corpus

A B

76

Gambar mikroskopis gastritis kronis. A. Infitrasi sel radang MN grade 1. D. Infitrasi sel radang MN grade 2. C. Infiltrasi inflammasi PMN. D. Atrofi pada antrum. E. Atrofi pada corpus. F. Metaplasia intestinal.

A B

C D

E F

LAMPIRAN 3. TABEL OUTPUT

LAPORAN STATISTIK

FREQUENCIES VARIABLES=Jenis_Klamin Suku DD Inflmsi_Krn_Ant Aktf_PMN_Ant Atf_Kel_Ant Met_Ints_Ant H_Plyr_Ant Inflmsi_Krn_Crp Aktf_PMN_Crp Atf_Kel_Crp Met_Ints_Crp H_Plyri_Crp Diagnosa Grd_Atr_Ant St_OLGA

/PIECHART FREQ /ORDER=ANALYSIS.

Frequencies

Notes

Output Created 10-AUG-2020 12:11:58

Comments

Input Data D:\Tulisan\Analisis SPSS\Analisis dr.

Irma Sp.PA\Deskriptif.sav

Missing Value Handling Definition of Missing User-defined missing values are treated as missing.

Cases Used Statistics are based on all cases with valid data.

Resources Processor Time 00:00:03,42

Elapsed Time 00:00:03,36

78

Frequency Percent Valid Percent

Cumulative

Frequency Percent Valid Percent Cumulative Percent

Valid Karo 2 1,8 1,8 1,8

Frequency Percent Valid Percent Cumulative Percent

Valid Susp. Ca Gaster 1 ,9 ,9 ,9

Inflammasi Kronis Antrum

Frequency Percent Valid Percent Cumulative Percent

Valid 1,00 84 73,7 73,7 73,7

2,00 20 17,5 17,5 91,2

3,00 10 8,8 8,8 100,0

Total 114 100,0 100,0

Aktifitas PMN Antrum

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 95 83,3 83,3 83,3

1,00 14 12,3 12,3 95,6

2,00 5 4,4 4,4 100,0

Total 114 100,0 100,0

Atrofi Kelenjar Antrum

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 91 79,8 79,8 79,8

1,00 18 15,8 15,8 95,6

2,00 5 4,4 4,4 100,0

Total 114 100,0 100,0

Metaplasia Intestianal Antrum

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 103 90,4 90,4 90,4

1,00 10 8,8 8,8 99,1

2,00 1 ,9 ,9 100,0

Total 114 100,0 100,0

H.Pylori Antrum

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 111 97,4 97,4 97,4

1,00 2 1,8 1,8 99,1

2,00 1 ,9 ,9 100,0

Total 114 100,0 100,0

Inflammasi Kronis Corpus

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 3 2,6 2,6 2,6

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 97 85,1 85,1 85,1

1,00 15 13,2 13,2 98,2

2,00 2 1,8 1,8 100,0

Total 114 100,0 100,0

80

Atrofi Kelenjar Corpus

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 102 89,5 89,5 89,5

1,00 7 6,1 6,1 95,6

2,00 5 4,4 4,4 100,0

Total 114 100,0 100,0

Metaplasia Intestianal Corpus

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 106 93,0 93,0 93,0

1,00 6 5,3 5,3 98,2

2,00 2 1,8 1,8 100,0

Total 114 100,0 100,0

H..Pylori Corpus

Frequency Percent Valid Percent Cumulative Percent

Valid ,00 114 100,0 100,0 100,0

Diagnosa

Frequency Percent Valid Percent

Cumulative Percent Valid Gastritis Chemical /

Gastropathy 72 63,2 63,2 63,2

Frequency Percent Valid Percent

Cumulative

Frequency Percent Valid Percent

Cumulative

/STATISTICS=STDDEV MINIMUM MAXIMUM MEAN MEDIAN SUM /ORDER=ANALYSIS.

Frequencies

Notes

Output Created 10-AUG-2020 12:20:20

Comments

Input Data D:\Tulisan\Analisis SPSS\Analisis dr.

Irma Sp.PA\Deskriptif.sav

Missing Value Handling Definition of Missing User-defined missing values are treated as missing.

Cases Used Statistics are based on all cases with valid data.

Resources Processor Time 00:00:00,00

Elapsed Time 00:00:00,00

82

LAMPIRAN 4.

SURAT TANDA BUKTI

TELAH DILAKUKAN PEMBACAAN ULANG SLAID

Judul Penelitian

Nama NIM Program Studi

:

: : :

Histomorfologi Gastritis Kronis dengan menggunakan klasifikasi Sydney system dan staging OLGA system di Laboratorium Patologi Anatomik Fakultas Kedokteran Universitas Sumatera Utara Medan

dr. Siti Aisyah 187041096

Program Magister Kedokteran Klinik Ilmu Patologi Anatomik

Telah dilakukan pembacaan ulang slaid pada : Hari / Tanggal : Selasa, 4 Agustus 2020

Didampingi oleh : 1. Dr. dr. Betty, M. Ked. (PA), Sp. PA

2. Dr. dr. Lidya Imelda Laksmi, M. Ked. (PA), Sp. PA

LAMPIRAN 5. SURAT IZIN PENELITIAN

84

LAMPIRAN 6. SURAT PERSETUJUAN KOMITE ETIK

Dalam dokumen TESIS OLEH : SITI AISYAH NIM : (Halaman 79-104)