MEDICAL BIOLOGY
E. IMMUNOPARASITOLOGY LABORATORY
1. Development of model anti-parasite vaccines —G. F. Mitchell, R. F. Anders, E. Handman.
2. Development of model immunodiagnosiic reagents for parasitic infection based on hybridoma antibodies —G. F. Mitchell, R. F. Anders.
3. Analysis of mouse strain variation in susceptibility to infection with various mciazoan and protozoan parasites —G. F. Mitchell, R. F. Anders.
4. Immunological aspects of intestinal parasitism —R. F. Anders, G. F. Mitchell.
5. Immunological and molecular biological aspects of malaria and babesiosis —G. V. Brown, R. F. Anders.
6. Development of methods for the identification and isolation of filarial antigens — R. F.
Anders.
7. Immunological aspects of cutaneous leishmaniasis infection —E. Handman, G. F. Mitchell.
8. Studies on mechanisms of evasion of host-protective immunities utilized by parasites —G. F.
Mitchell.
F. BIOCHEMISTRY AND BIOPHYSICS UNIT 1. Differentiation of T and B lymphocytes-K. Shortman, R. Scollay.
2. Physical techniques for cell separation —K. Shortman.
3. Organization and rearrangement of immunoglobin genes — S. Cory, D. Kemp, O. Bernard, J. Adams.
4. Structure of immunoglobulin genes —O. Bernard, .1. Adams.
5. Expression of immunoglobulin genes—D. Kemp, S. Cory, J. Adams.
PUBLISHED WORK Chapters of Books
1. ANDERS, R. F. — Developments in immunological technology, in Proc. Australian Develop- ment Assistance Bureau Research f o r Development Seminar, No. 3, Svdney, 1979: Tropical immunology, cd. L. Davidson, Commonwealth Institute of Health, Sydnev: 129-138 (1980).
2. CHEERS, C., McKENZIE, 1. F. C , MANDEL, T. E. and YU YU C H A N - A single gene (Lr) controlling natural resistance to murine listeriosis, in Genetic control of natural resistance to infection and malignancy, eds. E. Skamcne, P. A. L. Kongshaven and M . Lan- dy, Academic Press, New York: 141-148 (1980).
3. MACKAY, I. R. — Immunological interactions involving virus and liver: a synthesis, in Virus and the liver, eds. L. Bianchi, W. Gerok, K. Sickinger and G. A. Stalder, MTP, Lancaster;
section 14: 131-135 (Falk Symposium No. 28) (1980).
4. MACKAY, I . R. — Immunopaihology: a current overview, in Proc. Australian Development Assistance Bureau Research f o r Development Seminar, No. 3, Sydney, 1979: Tropical im- munology, cd. L. Davidson, Commonwealth Institute of Health, Sydney: 110-119 (1980).
5. METCALF, D. — Biological control systems in cancer, in Cancer, causes and control, cd. D.
Metcalf, Australian Academy of Science, Canberra: 4-22 (1980).
6. MILLER, J. F. A. P.— Early events after contact with foreign antigens, in Strategies of im- mune regulation, eds. E. E. Sercarz and A. J. Cunningham, Academic Press, New York:
333-336 (1980).
7. MILLER, J. F. A. P — Immunoregulation by T lymphocytes, in Strategies of inunune regula- tion, eds. E. E. Sercarz and A. J. Cuningham, Academic Press, New York: 63-76 (1980).
8. MILLER, J. F. A. P. —T cell dependent inflammatory responses, in Inflammation:
mechanisms and treatment, MTP, Lancaster: 107-112 (1980).
9. MILLER, J. F. A. P. and ARNOLD, B.-Specific suppressor T cell hybridomas, in Transplantation and clinical immunology, Vol. I I : Proc. 11th Int. Course, Lvon, 1979, Ex- cerpta Medica, Amsterdam: 95-100 (1980).
10. MITCHELL. G. I-. — Discussions on aspecis of the immunology of microbial diseases. 111.
Protozoa, in Proc. Australian Development Assistance Bureau Research f o r Development Seminar, No. 3, Svdnev, 1979: Tropical immunology, ed. L. Davidson, Commonwealth In- stitute of Health, Sydney: 60-67 (1980).
11. MITCHELL, G. F. and CHAPMAN, C. B. —Immunity against mctazoan and protozoan parasites, in Australian advances in veterinary science, 1980. Proc. of the Australian Vcterinarv Association Conference, Hobart, 1980, Australian Veterinary Association, Hobart: 19-20 (1980).
12. NOSSAL, G. J. V.—At what B cell developmental stage does clonal commitment occur, in Strategies of immune regulation, eds. E. E. Sercarz and A. J. Cunningham, Academic Press, New York: 263-265 (1980).
13. NOSSAL, G. J. V.—Concluding remarks (Symposium on Cancer, causes and control, Australian Academy ofScience, May, 1980), in Cancer, causes and control, ed. D. Metcalf, Australian Academy of Science, Canberra: 119-121 (1980).
14. NOSSAL, G. J. V. — Immunological tolerance: cellular facts and clinical speculations (The 1980 Lilly Lecture of the Royal College of Physicians of London), in Advanced medicine, 16:
Proc. 16th Advanced Medicine Conference of the Roval College of Phvsicians, ed. A. J.
Bellingham, Pitman, London: 356-369 (1980).
15. NOSSAL, G. J. V. — Institutional linkages in trans-national research —roles for public and private sectors, in Proc. Australian Development Assistance Bureau Research f o r Develop- ment Seminar, No. 3, Sydney, 1979: Tropical immunology, cd. L. Davidson, Com- monwealth Institute of Health, Sydney: 183-186 (1980).
16. NOSSAL, G. J. V. —Varying sensitivities to tolerance induction throughout maturation, in Strategies of immune regulation, eds. E. E. Sercarz and A . J . Cunningham, Academic Press, New York: 517-520 (1980).
17. TAIT, B. D., MACKAY, 1. R., KASTELAN, A., DAUSSET, J., MAYER, S. and OKOCHI, K.—Chronic liver disease including chronic active hepatitis, in Proc. 8th Histocompatibility Workshop, Los Angeles, Feb., 1980: Histocompatibility testing, 1980, ed. P. 1. Terasaki, UCLA, Tissue Typing Laboratory, Los Angeles: 657-661 (1980).
Articles
18. ADAMS, J. M.—The organization and expression of immunoglobulin genes. Immunology Todav, 1: 10-17 (1980).
19. ADAMS, J. M . , GOUGH, N. M . , WEBB, E. A., TYLER, B. M . , JACKSON, J. and CORY, S. — Molecular cloning of mouse immunoglobulin heavy chain mRNAs coding for / i , a, y \ , 72a, and y} chains. Biochemistry, 19: 2711-2719 (1980).
20. ASHERSON, G. L., ZEMBALA, M . . THOMAS, W. R. and PERERA, M . A. C. C - Supressor cells and the handling of antigen. Immunol. Rev., 50: 1-45 (1980).
21. BERNARD, O. and GOUGH, N. M. — Nucleotide sequence of immunoglobulin heavy chain joining segments between translocated VM and n constant region genes. Proc. Nal. Acad. Sci.
USA, 77: 3630-3634 (1980).
22. BOYD, A. W. and SCHRADER, J. W.-Mechanism of effector cell blockade. I . Antigen in- duced suppression of Ig synthesis in a hybridoma cell line, with cell-associated antigen. J.
Exp. Med., 151: 1436-1451 (1980).
23. BROWN, G. V., BATTYE, F. L. and HOWARD, R. J.-Separaiion of stages of Plasmodium falciparum-Meded cells using a fluorescence activated cell sorter. Amer. J.
Trop. Med. Hvg., 29: 1147-1149 (1980).
24. BURGESS, A. W., CRUISE, K. M . , MITCHELL, G. F. and WATT, S. M. - Preparation and surface labelling of murine eosinophilic polymorphonuclear leukocytes. Exp. Hematol., 8: 108-120 (1980).
25. BURGESS, A. W. and METCALF, D. — Characterization of a serum factor stimulating the differentiation of myclomonocytic leukemic cells. Int. J. Cancer, 26: 647-654 (1980).
26. BURGESS, A. W. and METCALF, D. — The nature and action of granulocyte-macrophage colony stimulating factors. Blood, 56: 947-958 (1980).
M E D I C A L BIOLOGY 143
27. BURGESS, A . \ V „ M E T C A L F , D., RUSSELL, S. H. M . and N I C O L A , N. A . - Granulocytc/macrophagc, megakaryocyte, eosinophil and cryihroid-colony stimulating fac- tors produced by mouse spleen cells. Biochem. J . , 185: 301-314 (1980).
28. B U R T O N , R. C. and W A R N E R , N. L . - T u m o r immunity to murine plasma cell tumors. V.
Genetic control o f the in v i n o cytotoxic T-cell respunse lo plasma cell lumor-associated an- tieens of N Z B mice. J. Nat. Cancer Inst., 65: 431-440 (1980).
29. B U X T O N , B., L A M B E R T , R. P. and P I T T , T . T . E . - T h e significance of vein wall thickness and diameter in relation to thc patency o f femoro-popliteal saphenous vein bypass grarts. Surgerv, 87: 425-431 (1980).
30. C A W L E Y , J . C. and BURNS, G. F.—Thc cytochemistry of human lymphoreticular sub- populations. Immunology Today, I: 85-90 (1980).
31. C E R E D I G , Rh. — Frequencies of allorcactive cytotoxic T lymphocyte precursors responding to H-2 antigens alone. Immunology, 40: 163-169 (1980).
32. C O O P E R , P. C , COFFEY, M . F., A N D E R S , R. F. and M A C K A Y , 1. R. — Delayed-type hypersensitivity to liver F antigen in the mouse. J. I m m u n o l . , 124: 790-794 (1980).
33. C O R Y , S. and A D A M S , J. M . - Deletions are associated with somatic rearrangement o f im- munoglobulin heavy chain genes. Cell, 19: 37-51 (1980).
34. C O R Y , S., A D A M S , J. M . and K E M P , D. J. —Somatic rearrangements forming active i m - muiiogloblin p. genes in B and T lymphoid cell lines. Proc. Nat. Acad. Sci. USA, 77:
4943-4947 (1980).
35. C O R Y , S., J A C K S O N , J. and A D A M S , J. M . — Deletions within the constant region locus can account for switches in immunoglobulin heavy chain expression. Nature, 285: 450-456 (1980).
36. C R A I G , P. S., M I T C H E L L , G. F., C R U I S E , K. M . and R I C K A R D , M . D . - H y b r i d o m a antibody immunoassays for the detection o f parasitic infection: attempts to produce an i m - munodiagnostic reagent for a larval taeniid cestode infection. Aust. J. Exp. Biol. Med. S c i , 58: 339-350 (1980).
37. D A W K I N S , H. J. S.. G R O V E , D. I., D U N S M O R E , J. D. and M I T C H E L L , G. F . - Strongyloides ratti: susceptibility to infection and resistance to reinfection in inbred strains of mice as assessed bv the excretion o f larvae. Int. J. Parusitol., 10: 125-130 (19S0).
38. D c L U C A , D., M A N D E L , T. E., L U C K E N B A C H , G. A . and K E N N E D Y , M . M . —Tolerance induction by fusion of fetal thymus lobes in organ culture. J. Immunol.. 124:
1821-1829 (1980).
39. D E X T E R , T . M . , G A R L A N D , J . , SCOTT, D., S C O L N I C K , E. and M E T C A L F , D. — Growth o f factor-dependent haemopoietic precursor cell lines. J. Exp. Med.. 152: 1036-1047 (1980).
40. G O D I N G , J. W . - A n t i b o d y production bv hybridomas. J. Immunol. Methods, 39: 285-308 (1980).
41. G O L D S C H N E I D E R , I., M E T C A L F , D., B A T T Y E , F. and M A N D E L , T . - A n a l y s i s o f rat hemopoietic cells on thc fluorescence activated cell sorter. 1. Isolation o f pluripotent hemopoietic stem cells and granulocvte-macrophagc progenitor cells. J. Exp. Med., 152:
419-437 (1980).
42. G O L D S C H N E I D E R , I., M E T C A L F , D., M A N D E L , T . and B O L L U M , F. J . - A n a l y s i s o f rat hemopoietic cells on the fluorescence activated cell sorter. I I . Isolation of terminal deoxy- nuclcotidyl transfcrase-positive cells. J . Exp. M e d . , 152: 438-446 (1980).
43. G O U G H . N. M . , K E M P , D. j . , T Y L E R , B. M . , A D A M S , J. M . and CORY, S - I n t e r v e n - ing sequences divide the gene for thc constant region of mouse immunoglobulin y. chains into segments, each encoding a domain. Proc. Nat. Acad. Sci. USA. 77: 554-558 (1980).
44. G O U G H , N. M . , W E B B , E. A . , C O R Y , S. and A D A M S , J. M . - M o l e c u l a r cloning of seven mouse immunoglobulin x chain messenger ribonucleic acids. Biochemistry, 19:
2702-2710 (1980).
45. H A M I L T O N , J. A . , S T A N L E Y , E. R., BURGESS, A . W . and S H A D D U C K , R. K.
Stimulation of macrophage plasminogen activator production by colonv stimulating factors.
J. Cell. Phvsiol.. 103 : 435-445 (1980).
46. H A W K I N S , B. R., C H E A H , P. S., D A W K I N S , R. L., W H I T T I N G H A M , S., B U R G E R , H. G . , P A T E L , Y., M A C K A Y , I. R. and W E L B O R N , T . A . - T h e diagnostic significance of thyroid microsomal antibodies in a randomly selected population. Lancet, I I : 1057-1059 (1980).
47. H O G A R T H , P. M . , C R U I S E , K. M . , M c K E N Z I E , I. F. C. and M I T C H E L L , G. F . - S u r - face markers of a purified peritoneal eosinophil population from Mesocestoides corti- infected B A L B / c male mice. ./. I m m u n o l . , 124: 406-411 (1980).
48. H O W A R D , M . , B A K E R , J . , T E A L E , J. and S H O R T M A N , K . - A n t i g e n - i n i t i a t e d B-lymphocyte differentiation. X V I I . The inhibitory effects o f recent antigen preprinting on thc subsequent responsiveness of'pro-progenitor' B cells. Scand. J. Immunol.. 11: 327-334 (1980).
49. H O W A R D . R. J . , C H A P M A N , C. B. and M I T C H E L L , G. F . - A difference in surface pro-
tcins of Fasciola hepatica larvae from imact and nude mice. Aust. J. Exp. Biol. Med. Sci..
58: 201-205 (1980).
50. HOWARD, R. J., SMITH, P. M . and MITCHELL, G. F.-Characterization of surface proteins and glycoproteins of red blood cells infected with haemosporidia. 1. Babesia roclhaini infections of BALB/c mice. Parasitology, 81; 251-272 (1980).
51. HOWARD, R. J., SMITH, P. M . and MITCHELL, G. F.-Characterization of surface proteins and glycoproteins of red blood cells infected with haemosporidia. I I . Plasmodium herghei infections of BALB/c mice. Parasitology, 81: 273-298 (1980).
52. HOWARD, R. J., SMITH, P. M . and MITCHELL, G. F.-Characterization of surface proteins and glycoproteins of red blood cells infected with haemosporidia. I I I . Plasmodium voelii infections of BALB/c mice. Parasitology, 81: 299-314 (1980).
53. HOWARD, R. J., RODWELL, B. J., SMITH, P. M., CALLOW, L. L. and MITCHELL.
G. F.— Comparison of thc surface proteins and glycoproteins on erythrocytes of calves before and during infection with Babesia bovis. J. Protozoal., 27: 241-247 (1980).
54. HOWARD, R. J. and SAWYER, W. H. — Changes in thc membrane microviscosity of mouse red blood cells infected with Plasmodium berghei detected using normal-(9-anthroylo.\y) fatty acid fluorescent probes. Parasitology, 80: 331-342 (1980).
55. HURLEY, J. C , DAY, K. P. and MITCHELL, G. F.-Accelerated rejection of Neinaiospiroidcs dubius intestinal worms in mice sensitized with adult worms. /l;/.sr. ./. Exp.
Biol. Med. Sci.. 58: 231-240 (1980).
56. JOHNSON, G. R.—Colonv formation in agar by adult bone marrow multi-potential hemopoietic cells. J. Cell. Physiol.. 103: 371-383 (1980).
57. JOHNSON, G. R. and METCALF, D. — Detection of a new tvpc of mouse eosinophil colonv by Luxol-Fast-Blue staining. Exp. Hematol., 8: 549-561 (1980).
58. KAY, T. W., PIKE, B. L. and NOSSAL, G. J. V.-Mechanisms of clonal abortion lolerogenesis. IV. Verification of the hypothesis in living mice. J. Immunol., 124: 1579-1584 (1980).
59. KEMP, D. J., HARRIS, A. W., CORY, S. and ADAMS, J. M. — Expression of thc im- munoglobulin C„ gene in mouse T and B Ivmphoid and mveloid cell lines. Proc. Nal. Acad.
Sci. USA, 77: 2876-2885 (1980).
60. KEMP. D. J., WILSON, A., HARRIS, A. W. and SHORTMAN, K . - T h e immunoglobulin li constant region gene is expressed in mouse thymocytes. Nature, 286: 168-170 (1980).
61. KRONBORG, I . J. and KNOPF, P. M. — Intrahepatic synthesis of immunoglobulin G in chronic liver disease. Ann. Acad. Med., Singapore, 9: 176-178 (1980).
62. LAYTON, J. E.— Anti-carbohydrate activity of T-cell-reactive chicken anti-mouse im- munoglobulin antibodies. J. Immunology, 125: 1993-1997 (1980).
63. LEVIN, J., LEVIN, F. C. and METCALF, D . - T h c effects of acute thrombocytopenia on mcgakarvocyte-CFC and granulocvlc-macrophage-CFC in mice: studies of bone marrow and spleen. Blood, 56: 274-283 (1980).'
64. MCCARTHY, J. H., MANDEL, T. E., GARSON, O. M . and METCALF, D . - T h c presence of mast cells in agar cultures. Exp. Hematol., 8: 562-567 (1980).
65. MCCARTHY, J. H., NICOLA, N., S Z E L A C I , G. and GARSON, O. M.-Studies on eosinophil colonies grown from leukemic and non-lcukemic patients. Leukemia Res., 4:
415-426 (1980).
66. MACKAY, I . R. — Immunologv of chronic hepatitis. Ann. Acad. Med., Singapore, 9:
167-171 (1980).
67. MACKAY, 1. R., GODYCK1, E. and TOURTELLOTTE, W. W.-Effect of multiple sclerosis materials on polymorphonuclear neutrophils of mice. Acta Neurol. Scand., 61: 1-8 (1980).
68. MACKAY, 1. R., ROSE, N. R. and CARNEGIE, P. R. —Germ-line deletion of genes coding for self-determinants. Nature, 288: 302-303 (1980).
69. MACKAY, 1. R. and TAIT, B. D. — HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotvpe by familv studies. Gastroenterology, 79:
95-98 (1980).
70. MACKAY, I . R., WHITTINGHAM, S., MATHEWS, J. D. and TAIT, B. D.-Genetic determinants of autoimmune chronic active hepatitis. Springer Seminars in Im- munopathology. Autoimmune liver disease, 3: 285-296 (1980).
71. MANDEL, T. E. and CHEERS, C. — Resistance and susceptibility of mice to bacterial infec- tion. I I I . Histopathology of listeriosis in resistant and susceptible strains. Infect. Immun., 30: 851-861 (1980).
72. MANDEL, T. E., H1GG1NBOTHAM, L., COLLIER, S., CARTER, W. and MARTIN, F.
1. R. — Effect of in vitro glucose concentration on fetal mouse pancreas cultures used as grafts in syngeneic diabetic mice. Transplantation, 30: 231-233 (1980).
73. MANDEL, T. E., HOFFMAN, L., COLLIER, S., CARTER, W., MARTIN, F. 1. R. and CAMPBELL, D.—Transplantation of islets of Langerhans in experimental diabetes mellitus. Proc. of The Endocrine Society of Australia, 23: 2-3 (1980).
MEDICAL BIOLOGY 145 74. MANDEL, T. E., PH1PPS, R. P., ABBOT, A. and TEW, J. G . - T h e follicular dendritic
cell; long term antigen retention during immunity. Immunol. Rev., 53: 29-59 (I980).
75. MARCHALONIS, J. J., WARR, G. W., SANTUCCI, L. A., SZENBERG, A., von FELLENBERG, R. and BURCKHARDT, J. J.-The immunoglobulin-like T-cell receptor.
IV. Quantitative cellular assay and partial characterization of a heavy chain cross-reactive with the FD fragment of serum p. chain. Mol. Immunol., 17: 985-999 (1980).
76. METCALF, D. —Clonal analysis of thc proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte- macrophage precursors. Proc. Nal. Acad. Sci. USA, 77: 5327-5330 (1980).
77. METCALF, D. —Clonal extinction of myclomonocytic leukaemic cells by serum from mice injected with endotoxin. //;(. J. Cancer, 25: 225-233 (1980).
78. METCALF, D., JOHNSON, G. R. and BURGESS, A. W.-Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells. Blood, 55:
138-147 (1980).
79. MITCHELL, G. F., CURTIS, J. M . , HANDMAN, E. and McKENZIE, 1. F. C - Cutaneous leishmaniasis in mice: disease patterns in reconstituted nude mice of several genotypes infected with Leishmania tropica. Aust. J. Exp. Biol. Med. Sci., 58: 521-532 (1980).
80. MITCHELL, G. F., RAJASEKARIAH, G. R. and RICKARD, M . D . - A mechanism to ac- count for mouse strain variation in resistance to the larval cestode, Taenia laeniae/orrnis. Im- munology, 39: 481-489 (1980).
81. MORSTYN, G., NICOLA, N. A. and METCALF, D. - Purification of hemopoietic pro- genitor cells from human marrow using a fucosc binding lectin and cell sorting. Blood, 56:
798-805 (1980).
82. MOTTRAM, P. L. and MILLER, J. F. A. P. - Delayed-type hypersensitivity induced by antigen-pulsed bone marrow-derived macrophages. Eur. J. Immunol., 10: 165-170 (1980).
83. NICOLA, N. A., BURGESS, A. W., STABER, F. G., JOHNSON, G. R., METCALF, D.
and BATTYE, F. L. — Differential expression of lectin receptors during hemopoietic differen- tiation: enrichment for granulocyte-macrophage progenitor cells. J. Cell. Physiol., 103:
217-237 (1980).
84. NICOLA, N. A., MORSTYN, G. and METCALF, D. — Lectin receptors on human blood and bone marrow cells and their use in cell separation. Blood Cells, 6: 563-579 (1980).
85. NOSSAL, G. J. V.—Antibody formation: strategies of molecular recognition and cellular control. Records of the Australian Academy of Science, 4 (3): 53-71 (1980).
86. NOSSAL, G. J. V.—The case historv of Mr T. 1. —terminal patient or still curable? Im- munology Today, I : 5-9 (1980).
87. NOSSAL, G. J. V.-Global and regional strategy. World Health, World Health Organiza- tion, Geneva: 20-24 (April 1980).
88. NOSSAL, G. J. V. —Human insulin through recombinant DNA technology. Med. J. Ausi.
(Editorial), 2: 295-296 (1980).
89. NOSSAL, Ci. J. V. and PIKE, B. L. — Clonal anergy: persistence in tolerant mice of antigen- binding B lymphocytes incapable of responding to antigen or mitogen. Proc. Nal. Acad. Sci.
USA. 77: 1602-1606 (1980).
90. O'DONNELL, I . J. and MITCHELL, G. F . - A t i investigation of the antigens of Ascaris tuinbricoides using a radioimmunoassay and sera of naturally infected humans. //)/. Arch.
Allergv Appl. Immunol., 61: 213-219 (1980).
91. OLOBO, J. O., HANDMAN, E., CURTIS, J. and MITCHELL, G. F. — Antibodies lo Leishmania tropica promastigotes during infection in mice of various genotypes. Aust. ./.
Exp. Biol. Med. Sci.. 58: 595-601 (1980).
92. PENSCHOW, J. and MACKAY, 1. R . - N K and K cell activity of human blood: differences according to sex, age and disease. Ann. Rheum. Dis., 39: 82-86 (1980).
93. PETERS, M., MACKAY, I . R. and BUCKLEY, .1. D.-Occurrence of tumors and effects of longevity after limited x-irradiation in man. Amer. J. Path., 101: 647-655 (1980).
94. PHIPPS, R. P., MITCHELL, G. P., MANDEL, T. E. and TEW, J. G.-Antibody isotypes mediating antigen retention in passively immunized mice. Immunology, 40: 459-466 (1980).
95. PHIPPS, R. P., TEW, J. G., MILLER, G. A. and MANDEL, T. E . - A murine model for analysis of spontaneous induction and feedback regulation of specific antibody synthesis.
Immunol, Commun., 9: 55-70 (1980).
96. PIKE, B. L., KAY, T. W. and NOSSAL, G. J. V. - Relative sensitivity of fetal and newborn mice to induction of hapten-specific B cell tolerance. J. Exp. Med., 152: 1407-1412 (1980).
97. PROUDFOOT, A. D. and MACKAY, I . R. —Utility analysis of a computer stored diagnosis index and other medical record dala. Ausi. N.Z. J. Med., 10: 314-319 (1980).
98. PROWSE, S. J. and MITCHELL, G. F . - O n the choice of mice for dissection of strain variations in thc development of resistance to infection with Nematospiroides dubius. Ausi.
J. Exp. Biol. Med. Sci.. 58: 603-605 (1980).
99. RAJASEKARIAH, G. R., MITCHELL, G. F. and RICKARD, M. D.-Taenia taeniafor-
mis in mice: protective immunization with oncospheres and their products. Int. J. Parasitol..
10: 155-160 (1980).
100. RAJASEKARIAH, G. R., RICKARD, iM. D. and MITCHELL, G. F. - Density gradient separation of Taenia pisiformis oncospheres. J. Parasitol., 66: 355-356 (1980).
101. RAJASEKARIAH, G. R., RICKARD, M. D. and MITCHELL, G. F. — Immunization of mice against infection with Taenia laeniaformis using various antigens prepared from eggs, oncospheres, developing larvae and strobilocerci. Int. J. Parasitol., 10: 315-324 (1980).
102. ROBERTS-THOMSON, I . C , MITCHELL, G. F.. ANDERS, R. F.. TAIT, B. D., KERLIN, P., KERR-GRANT, A. and CAVANAGH, P.-Genetic studies in human and murine giardiasis. Gut. 21: 397-401 (1980).
103. RODGER, B., WHITTINGHAM, S., MARTIN, F. I . R., HAWKINS, B. R., DAWKINS, R. L. and WELBORN, T. A. —A population survey of pancreatic islet cell anti-bodies. Clin.
Exp. Immunol., 39: 125-129 (1980).
104. SCHRADER, J. W., ARNOLD, B. and CLARK-LEWIS, l . - A T cell hybridoma stimulated with concanavalin A releases factors affecting both haemopoietic colony-forming cells and B cell antibody responses. Nature, 283: 197-199 (1980).
105. SCHRADER, J. W. and NOSSAL, G. J. V.-Strategies Tor the analysis of accessory-cell function; the in vitro cloning and characterization of thc P cell. Immunol. Rev., 53: 61-85 (1980).
106. SCHUMACHER, M . J.— Characterization of allergens from urine and pelts of laboratory mice. Molec. Immunol.. 17: 1087-1095 (1980).
107. SCHUMACHER, M . J. — The effect of a /3-adrenergic agonist, fenoterol, on nasal sensitivity to allergen. J. Allergv Clin. Immunol., 66: 33-36 (1980).
108. SCHUMACHER, M . J. and MITCHELL, G. F. - Inhibition of murine reaginic antibody responses bv nasal immunotherapy with modified allergen. Int. Arch. Allergv Appl. Im- munol., 62: 382-388 (1980).
109. SHORTMAN, K.—Citation Classics: The separation of different cell classes from lymphoid organs. I I . The purification and analysis of lymphocyte populations by equilibrium density gradient centrifugation. Current Contents, 23 (14): 12 (1980).
110. STABER, F. G. — Diminished response of granulocyte-macrophage colony stimulating fac- tor (GM-CSF) in mice after sensitization wilh baclcrial cell-wall components. Exp.
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114. STABER. F. G. and METCALF, D. —Humoral regulation of splenic hemopoiesis in mice.
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115. STEVEN, M . M . and MACKAY, 1. R. —Prognosis of pregnancy in chronic liver disease.
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116. TEALE, J. M . and MANDEL, T. E. —The ontogenic development of B lymphocyte func- tion and tolerance susceptibility in vivo and in an in vitro fetal organ culture system. J. Exp.
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THESES PASSED FOR HIGHER DEGREES Doctor of Philosophy
1. CEREDIG, Rh. — In vitro studies of cell mediated immunity to human and murine tumour associated antigen.
2. GOUGH, N. M. — Control of immunoglobulin gene expression
3. McCARTH Y, J. H. — Regulation of granulocyte and macrophage populations in leukaemia.
4. SMITH, F. I. —Activation of T lymphocytes in cellular immunity.
THESES IN PROGRESS PhD Theses in Progress
1. BOYD, A. —Cell surface phenomena and immunological unresponsiveness.
2. BUCKLEY, J. D. — Cancer epidemiology and diagnosis.
3. CHAPMAN, C. — Immunological aspecis of Fasciola hepatica infections of sheep and cattle.
4. CLARK-LEWIS, 1. — Biochemical studies of lymphocyte differentiation.
5. COLLIER, S. — Organ and tissue culture studies of pancreatic islet cells.
6. COOPER, P. —Molecular regulation of haemopoiesis.
7. COPPEL, R. — Studies on human filariasis and malaria.
8. COWMAN, A. — Molecular cloning and analysis of immunoglobulin genes from T cells.
9. GERONDAK1S, S. — Gene organization in the immunoglobulin heavy chain locus.
10. JENNINGS, G.~ Differentiation and clonal proliferation of B cell subsets.
11. KAHL, L. — Biochemical and immunological aspecis of red cell invasion by babesia parasites.
12. LAYTON, .1. E. — The function of lymphocyte surface IgM and IgD during B cell matura- tion.
13. LOWENTAH L, .1. - Radiobiology of lymphoid cells.
14. MORAHAN, Ci. — Production and characterization of functional T and B cell hybridomas.
15. MORSTYN, G. — Analysis of ihe nature and control of normal and leukaemic cells.
16. PIKE, Yi. — Differentiation of B lymphocytes and their interaction with antigen.
17. TYLER, Yi.—Expression of immunoglobulin genes.
MSc Theses in Progress 18. FORSYTH, K. — Antigens o/Onchocerca gibsoni.
19. GAMBLE, }. — T cell hybridomas, their production and characterization.
20. MOTTRAM, P. —The role of the macrophage in delayed type hypersensitivity.