5. KITCHEN, W. H., McDOUGALL, A. B. and NAYLOR, F. D . - A Longitudinal Study of Verv Low Birthweiehi Infants. I I I . Distance Growih at Eight Years of Aec. Dev. Med. &
Child Neur., 22: 163-171 (1980).
6. KITCHEN, W. H . , RYAN, M . M . , RICKARDS, A., McDOUGALL, A. B., BILLSON. F.
A., KE1R, E. H. and NAYLOR, F. D . - A Longitudinal Study of Very Low Birthweight In- fants. IV. An Overview of Performance at Eight Years of Age. Dev. Med. <t Child Neur.. 22:
172-188 (1980).
7. KUHN, R. J. P. — Chemoprophvlaxis with Tinidazole in Major Gynaecological Surgery.
Aust. N.Z. J. Obstel. Gvnaec., 20: 43-46 (1980).
8. KUHN, R. J. P., LONG, A. R. and FORTUNE, D. W.-Choriocarcinoma Coexistent with Intrauterine Pregnancy. Aust. N.Z. J. Obstet. Gynaec, 20: 94-98 (1980).
9. LOPATA, A. — Successes and Failures in Human in Vitro Fertilization. Nature, 2SS: 642-643 (1980).
10. LOPATA, A., JOHNSTON, W. I . FL, HOULT, I . J. and SPEIRS, A. L. — Pregnancy Following Intrauterine Implantation of an Embrvo Obtained bv in Vitro Fertilization of a Preovulatory Egg. Fend. Stent., 33: 117-120 (1980).
11. LOPATA, A., SATHANANTHAN, A. H., McBAIN, J. C , JOHNSTON, W. I . H. and SPEIRS, A. L. —Thc Ultrastructure of the Preovulatory Human Egg Fertilized in Vitro. Fer- lil. Sleril, 33: 12-20 (1980).
12. McBAIN, J. C , EVANS, J. H . , PEPPERELL, R. J., ROBINSON, H. P., SMITH, M. A.
and BROWN, J. B . - A n Unexpectedly High Rate of Ectopic Pregnancy Following Induc- tion of Ovulation with Human Pituitary and Chorionic Gonadotrophins. Brit. J. Obstel.
Gvnaec, 87: 5-9 (1980).
13. M'URPHY, A. J., JALLAND, M . , PEPPERELL, R. J. and QUINN, M. A . - U s e of Vaginal Prostaglandin Gel before Induction of Labour. Aust. N.Z. J. Obstet. Gvnaec. 20:
84-86 (1980).
14. O'HERLIHY, C —Pregnancy in an Acromegalic after Bromocriptine Therapy. Ir. ./. Med.
Sci., 149: 381-382 (1980).
15. O'HERLIHY, C. — Heparinoid Cream in Pregnancy-Associated Superficial Throm- bophlebitis. Practitioner, 224: 1202-1203 (1980).
16. O'HERLIHY, C , de CRESPIGNY, L. J. Ch., LOPATA, A., JOHNSTON, L, HOULT, 1.
and ROBINSON, H. — Prc-ovulatory Follicular Size: A Comparison of Laparoscopic and Ultrasound Measurements. Fertil. Sleril., 34: 24-26 (1980).
17. O'HERLIHY, C , de CRESPIGNY, L. J. Ch., and ROBINSON, H. P. - Monitoring Ovarian Follicular Development with Real-Time Ultrasound. Brit. J. Obstet. Gvnaec, 87:
613-618 (1980).
18. O'HERLIHY, C , de CRESPIGNY, L. J. Ch., and ROBINSON, H. P. — Miltclschmcrz is a Preovulatory Symptom. Brit. Med. J., 280: 986 (1980).
19. O'HERLIHY, C. and MARTIN, R. H.-Screening for Fetal Risk with Urinary Oestrogen:
Creatinine Ratio at 34 Weeks. Brit. J. Obstel. Gvnaec, 87: 388-392 (1980).
20. O'HERLIHY, C , PEPPERELL, R. I . and EVANS, J. H . - T h e Significance of FSH Eleva- tion in Young Women with Disorders of Ovulation. Brit. Med. ./., 281: 1447-1450 (1980).
21. QUINN, M. A., SHEKLETON, O., WEIN, R. and KLOSS, M.-Single Dose Prostaglandin Gel for Mid-Trimester Termination of Pregnancy. Aust. N.Z. J. Obstel. Gvnaec, 20: 77-79 (1980).
22. QUINN, M . A. and BROWN, J. B. - Endogenous Sex Hormones and Cancer. Evaluation of thc Carcinogenic Risk of Chemicals to Humans: Sex Hormones I I . I.A.B.C. Monogr., 21:
33-95 (1980).
23. RETI, L. L., ADEY, F. D. and BROWN, M. F -Excessive Bleeding from Fetal Scalp Blood Sampling. Ausi. N.Z. J. Obstet., Gvnaec. 20: 55-57 (1980).
24. ROBINSON, H. P., HOOD, V. D.. A D A M , A. H., GIBSON, A. A. M . and FERGUSON- SMITH, M. A. — Diagnostic Ultrasound: Earlv Detection of Fetal Neural Tube Defects.
Obstel. & Gvnec. 56: 705-710 (1980).
25. SATHANANTHAN, A. H. and LOPATA, A. — Ultrastructure of Human Eggs: Aspirated Preovulatory Mature Ova Prior to Fertilization. Micron.. I I : 469-470 (1980).
26. TRICHOPOULOS, D., MacMAHON, B. and BROWN, J. B. -Socioeconomic Status, Urine Estrogens and Breast Cancer Risk. J. Nail. Cancer Inst., 64: 753-755 (1980).
27. TROUNSON, A. O., SHIVERS, C. A., McMASTER, R. and LOPATA, A. - Inhibition of sperm binding and fertilization of human ova by antibody to porcine zona pellucida and human sera. Arch. Androl, 4: 29-36 (1980).
THESIS PASSED FOR HIGHER DEGREE Master of Gynaecology and Obstetrics
1. QUINN, M. A. — Clinical Applications of Prostaglandin Gel in Obstetrics and Gynaecology.
OBSTETRICS AND GYNAECOLOGY (ROYAL WOMEN'S HOSP.) 177
THESES IN PROGRESS PhD Thesis in Progress
1. CLARKE, G. N. —Studies in ihe Biology and Crvopreservation of Human Spermatozoa.
MSc Theses in Progress
2. BASCOM B, J. — Development of Radioimmunoassay for Oestrogen Glucuronides and their Application for Monitoring Human Female Reproductive Functions.
3. BRIGHT, M. I. — Development of Pregnanediol Clucuronide Assay. Its Application lo the Detection of Ovulation and as a Placental Function Test in Pregnancy.
MD Theses in Progress
4. de CRESPIGNY, L. J. Ch. — The Investigation of Neonatal Cerebroveniricular Hae- morrhage and ils Sequelae wilh Real-Time Ultrasound.
5. McBAIN, J. C-Idiopathic Infertility.
6. O'HERLIHY, C. — The Evaluation of Human Ovulation with Ultrasound and Endocrine Techniques.
7. QUINN, M. A. — Endocrine Profiles of patients with Gynaecological Cancer.
8. WADE, R. W. - Long-Term Follow-Up of Infants Born to Mothers with Low Oestriol Ex- cretion in Pregnancy.
SUBSTANTIAL GRANTS RECEIVED Grants have been received as follows:
A. E. Rowden White Foundation: Reproduction research.
NH & MRC: Endocrinology of gynaecological cancer.
NH & MRC: In vitro fertilization.
Anti-Cancer Council of Victoria: Endocrinology of Gynaecological cancer.
Sandoz (Australia) Pty. Ltd.: Prolactin and disorders of reproduction.
3AW Community Service Trust: Paediatric follow-up studies.
OBSTETRICS AND GYNAECOLOGY
MERCY AND AUSTIN HOSPITALS INTRODUCTION
Thc major research activities in the department were detection and treatment of abnormal glucose tolerance and fetal growth retardation during pregnancy. Surviving infanls born from thesc high-risk pregnancies continue to be followcd-up lo determine the quality of survival.
RESEARCH TOPICS IN PROGRESS 1. Treatment of fclal growth retardation before delivery —N. A. Beischer.
2. Study of abnormal glucose tolerance (gestational hypoglycaemia and gestational diabetes) in pregnancy —D. A. Abell.
3. Angiotcnsin-converting enzyme in pregnancies complicated by renal disease, hypertension and diabetes mellitus —J. N. Oats.
4. Blood volume changes in pregnancies complicated by intrauterine growth retardation — .!. N.
Oats.
5. Changes in plasma urate in pregnancy-induced hypertension —J. N. Oats, H. M . Walker.
6. Changes in skin vessels in pregnancy-induced hypertension —J. N. Oats, J. B. Hobbs.
7. Assessment of placental function in patients with pre-eclampsia—P. A. Long.
8. Studies of fetal heart rale patterns in late pregnancy — F. T. K. Chew. J. N. Oats.
9. Prevention of prematurity by treatment of undiagnosed incompetent cervix —G. J. Ratten.
10. Genetic counselling in pregnancy —J. E. Brehcny.
11. Follow-up of babies born from pregnancies associated with low maternal excretion of oestriol—J. H . Drew.
12. Treatment of the persistent fetal circulation syndrome in newborn infants with lolazolinc hydrochloride — .!. H. Drew.
13. Studv of the effects on survival of immediate intubation at birth of infants with a birth weight of 501 to 1500g.-J. H. Drew.
14. Study of late-onset convulsions in newborn infanls —J. H. Drew.
15. Obstetric factors in suddcn-infant-dcalh syndrome —.1. N. Oals, E. Farrell.
16. Evaluation of ulcrinc lavage in the early diagnosis of malignancy of the uterine body and cer- vix—C. A. Barbaro.
17. Use of provcra as primary treatment for carcinoma of the endometrium— R. Planner.
18. Assessment of the time of ovulation — L. Hatherley.
19. Whole blood viscosity in paticnls with pre-eclampsia —J. B. Hobbs, J . N. Oats.
20. Study of late-onset convulsions in newborn infants —J. H. Drew, H. J. Goldberg.
21. Analysis of infants with massive pulmonary haemorrhage —J. H. Drew, P. D. Sly.
22. Causative factors in air leaks in the newborn infant —J. H. Drew, P. D. Sly.
23. Hyperviscosity studies in newborn infants —J. H. Drew, J. B. Hobbs.
24. The timing of intracranial haemorrhage in newborn infanls by ultrasound estimation — J. H.
Drew, C. M . Acion.
PUBLISHED WORK Articles
1. ABELL, D. A. and BEISCHER, N. A.—Are There Recognizable Symptoms of Abnormal Glucose Tolerance (Hvpoglvcacmia and Hypcrglvcacmia) in Pregnancv? Aust. N.Z. J.
Obstel. Gvnaec., 20: 73-76 (1980).
2. BROUGHTON PIPKIN, F., OATS, J. N., and SYMONDS, E. M . — The Effect of a Specific AH Antagonist (Saralasin) on Blood Pressure in the Immediate Puerperium, in Pregnancy Hvpertension, eds. J. Bonnar, 1. MacGillivray and E. M . Symonds, M.T.P. Press Ltd., England: 75-80 (1980).
3. DREW, J. H . and BEISCHER, N. A. —Incidence, Associated Factors and Long-term Prog- nosis of Newborn Infants with Nerve Palsies, in Problems in Perinatology, eds. S. M . M . Karim and K. L. Tan, M.T.P. Press Ltd., England: 572-578 (1980).
4. DREW, J. H. and ARROYAVE, C. M . - T h e Complement Svstem of the Newborn Infant.
Biol. Neonate., 37: 209-217 (1980).
5. DREW, J. H.— Malformations: Incidence, Aetiologv, Problems and Possible Association with Infants of Multiple Births. Med. J. Aust., 1: 49-50 (1980).
6. DREW. J. H., SATCHWELL, C. A., CARMAN, P. G. and BEISCHER, N. A.-Prospec- tive Follow-up of Growth Retarded Infanls and of those from Pregnancies Complicated by Low Oestriol Excretion. Singapore J. Obstel. Gynaec, I I : 67-72 (1980).
7. DREW, J. H. — Breastfeeding and Jaundice. Nursing Mothers Association o f Australia Newsletter, 16: 3-7 (1980).
OBSTETRICS AND GYNAECOLOGY (MERCY AND AUSTIN HOSPS.) 179 8. HATHHRLEY, L. I . , HAYES, K., HENNESSY, E. M. and .IACK, I. — Herpes Virus in an
Obstelrie Hospilal I : Herpetic Eruptions Med. J. Ausi., 2: 205-208 (1980).
9. HATI-IERLEY, L. I . , HAYES, K. and JACK, I. — Herpes Virus in an Obsietric Hospital I I : Asymptomatic Virus Excretion in Stall" Members. Med. J. Ausi.. 2: 273-275 (1980).
10. HATHER1.EY, L. I . , HAYES, K., and JACK, I. — Herpes Virus in an Obstetric Hospilal I I I : Prevalence of Antibodies in Patients and Stalf. Med. J. Ausi.. 2: 325-329 (1980).
11. HILL, D.J. and BEISCHER, N. A. — Placenta Praevia Without Antepartum Haemorrhage.
Ausi. N.Z. J. Obslel. Gynaec., 20: 21-23 (1980).
12. HILL, D. J. and BEISCHER, N. A. — Hysterectomy in Obstetric Practice. Ausi. N.Z. .1.
Obslel. Gvnaec. 20: 151-153 (1980).
13. LONG, P. A., ABELL, D. A. and BEISCHER, N. A. — Fetal Growth Retardation and Pre- eclampsia. Brii. J. Obsiel. Gvnaec. 57: 13-18 (1980).
14. OATS, J. N., ABELL, D. A., BEISCHER, N. A. and BROOMHALL, G. R. — Maternal Glucose Tolerance During Pregnanes' with Excessive Size Infants. Obstel. Gvnec. 55:
184-186(1980).
15. OATS, J. J. N., BROUGHTON PIPKIN, I", and SYMONDS. E. M . - A Prospective Serial Study of Plasma Angiotensin 1 - Converting Enzyme in Pregnancy, in Pregnancy Hyperten- sion, eds. J. Bonnar, I . MacGillivrav and E. M. Svmonds, M.T.P. Press Ltd., England:
51-58 (1980).
16. WHIR, P. E., RATTEN, G. .1. and BEISCHER, N. A. — Acute Polyhydramnios-A Com- plication of Monozygous Twin Pregnanes'. Brit. J. Obstet. Gvnaec, 86: 849-853 (1979).
17. WEIR. P. H. and BEISCHER, N. A. — Birth Before Arrival in Hospital. Med. ./. Aust.. 2:
31-33 (1980).
THESES IN PROGRESS PhD Thesis in Progress
1. DREW, J. II. — Follow-up of infanls born from pregnancies complicated by low urinary oestriol excretion and of those suffering from fetal growih retardation.
MD Theses in Progress
2. ABELL, D. A. —The significance of abnormal glucose tolerance (hypoglycaemia and hyperglycaemia) in pregnancy.
3. HATHERLEY, 1... I. — Resumption of ovulation after term pregnancy and spontaneous first trimester abortion.
4. LONG, P. A. —Pre-eclampsia with reference to parity, onset in labour and relationship to fetoplacental function and abnormal glucose tolerance.
5. OATS, .1. N. — A study of angiotensin-converling-enzyine in normotensive primigravid pregnancies.
MGO Theses in Progress 6. ANDERSON, K. .1. — Study of glucose tolerance in pregnancy.
7. BARBARO, C. A. — Uterine lavage in the early diagnosis of endometrial malignancies and its precursors.
SUBSTANTIAL GRAN TS RECEIVE!) Grants have been received as follows:
Mental Health Research Fund: Investigation into thc Incidence of Mental Retardation and In- tellectual Impairment in Infants where Mothers had Low Oestriol Excretion in Pregnancy.
Thc Apex Foundation for Research into Menial Retardation Ltd.: Thc Relationship of Blood Flow in Newborn Infanls lo Mental Retardation.