Quality Assurance Division of Glaxo Smith Kline, Jakarta, Indonesia

CURRICULUM VITAE

PERSONAL INFORMATION

Name Aditya Fitriasari, M.Sc., Pharmacist

Home address Kweni Rt 03 No 172, Panggung Harjo, Sewon, Bantul, Yogyakarta 55188, Indonesia

Telephone +62 274 372787 Mobile: +62 81808665141 E-mail adityafitriasari@yahoo.com

Nationality Indonesian

Date of birth 20 November 1984

Gender Female

Marital status Married

WORK EXPERIENCES

Dates July 2010 – May 2011 Occupation or position held Research assistant

Main activities and responsibilities

Working in a research project : Identification of Anti-Hepatitis C Virus (HCV) Substances and Development of HCV and Dengue Vaccine

Name and address of employer

JICA Project, University of Indonesia, Faculty of Medicine, IASTH Building,

7th _{Floor, Jl Salemba Raya No 4, Jakarta Pusat 10430}

Dates January – July 2010 Occupation or position held Lecturer

Main activities and responsibilities

Preparing material (module) for Moleculer Biology teaching and tutorials

Name and address of employer

Pharmacy Division, Faculty of Medicine, Yogyakarta Muhammadiyah University, Yogyakarta, Indonesia

Dates September 2008 – December 2009 Occupation or position held Lecturer assistant in Molecular Biology

Main activities and responsibilities

Moleculer Biology teacher in the practical work

Name and address of employer

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Dates August 2008 - December 2009 Occupation or position held Research staff

Main activities and responsibilities

Working in a research team carrying out cancer chemoprevention researches

Name and address of employer

Cancer Chemoprevention Research Center, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

Dates March – April 2008 Occupation or position held Apprentice student

Main activities and responsibilities

Performance Qualification and Gap Analysis

Name and address of employer

Quality Assurance Division of Glaxo Smith Kline, Jakarta, Indonesia

Dates September 2004 - July 2006 Occupation or position held Practical work assistant

Main activities and responsibilities

Assisting the students at practical work of Basic Chemical Pharmacy, Organic Chemistry, Microbiology Pharmacy, and Technology and Formulation of Solid Dosage Forms

Name and address of employer

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

EDUCATION AND TRAINING

Dates September 2008 - January 2010 Title of qualification awarded Magister of Science in Pharmacy

GPA : 3.90 (Max 4.00) Principal

subjects/occupational skills covered

Drug Discovery and Development

Thesis Title : “Induction of Apoptosis and Cell Cycle Modulation by Naringenin to Increase The Cytotoxic Activity of Doxorubicin on MCF-7 Breast Cancer Cell Lines” Name and type of

organisation providing education and training

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

Dates September 2007 – July 2008 Title of qualification awarded Pharmacist

GPA : 3.86 (Max 4.00) Principal

subjects/occupational skills covered

Pharmacy Science and Industry

Name and type of organisation providing education and training

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

Dates September 2003 - August 2007 Title of qualification awarded Bachelor of Pharmacy

GPA : 3.86 (Max 4.00) Principal

subjects/occupational skills covered

Pharmacy Science and Industry

Thesis Title : “Proliferative Effect of Ethanolic Extract of Long Bean on Breast Cell”

Name and type of organisation providing education and training

Dates 11-12 September 2006 Title of qualification awarded Presenting Author

Principal subjects/occupational skills covered

The International Symposium on Recent Progress in Curcumin Research Presentation title : “The Potency Study of Curcumin and Its Analogues as Selective Estrogen Receptor Modulators (SERMs): Docking to Estrogen Receptors β”

Name and type of organisation providing education and training

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

Dates 3 September 2007 Title of qualification awarded Participant

Principal subjects/occupational skills covered

National Seminar : Diversifikasi Program Studi atau Peminatan dalam Pendidikan Tinggi Farmasi

Name and type of organisation providing education and training

Asosiasi Pendidikan Tinggi Farmasi Indonesia (APTFI)

Dates 11-12 August 2008 Title of qualification awarded Presenting Author

Principal subjects/occupational skills covered

Scientific Congress XVI of Association of Indonesian Pharmacist (IAI)

Presentation title : “Proliferative Effect of Ethanolic Extract of Long Bean on T47D Cell”

Name and type of organisation providing education and training

Association of Indonesian Pharmacist (IAI), Yogyakarta, Indonesia

Dates 24-25 November 2008 Title of qualification awarded Presenting Author

Principal subjects/occupational skills covered

International Joint Symposium Frontier In Biomedical Sciences : From Genes to Applications

Presentation title : “Modulation of Cell Cycle and Apoptotic Induction by

Pentagamavunon-0 and Doxorubicin Combination Toward MCF-7 Breast Cancer Cell”

Name and type of organisation providing education and training

Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia

Dates 16-17 July 2009

Title of qualification awarded Committee and Co-trainer Principal

subjects/occupational skills covered

Workshop Molecular Biology on Cancer : Western Blot

Name and type of organisation providing education and training

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

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Title of qualification awarded Presenting Author Principal

subjects/occupational skills covered

Symposium of Natural Drugs Research (PERHIPBA) XIV

Presentation title : “The Increase Cytotoxic Activity of Doxorubicin by Citrus Flavonoid, Tangeretin on Breast Cancer Cells MCF-7”

Name and type of organisation providing education and training

Badan Pengkajian dan Penerapan Teknologi, Jakarta, Indonesia

Dates 18-20 August 2009 Title of qualification awarded Finalist

Principal subjects/occupational skills covered

Ristek-Novartis Indonesia Biotechnology Leadership Camp

Name and type of organisation providing education and training

Novartis Indonesia and Ministry of Research and Technology, Jakarta, Indonesia

Dates 5-6 October 2009 Title of qualification awarded Presenting Author

Principal subjects/occupational skills covered

The International Conference on Pharmacy and Advanced Pharmaceutical Sciences

Presentation title : “Induction of Apoptosis and Cell Cycle Arrest by Naringenin to Increase The Cytotoxic Activity of Doxorubicin on Breast Cancer Cell Lines” Name and type of

organisation providing education and training

Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia

Dates 28-29 September 2010 Title of qualification awarded Participant

Principal subjects/occupational skills covered

International Seminar on Viral Diseases : Control and Management 2010

Name and type of organisation providing education and training

Faculty of Medicine, University of Indonesia Graduate School of Medicine, Kobe University

Dates 26-30 July 2010 Title of qualification awarded Trainee

Principal subjects/occupational skills covered

Biosafety Training

- Recognizing and Assesing Biological Hazard in The Laboratory - Biosafety Practices, Equipment, and Facility Safeguard

- Emergency Responses and Transport of Infectious Substances - Animal Biosafety

Name and type of organisation providing education and training

Institute of Human Virology and Cancer Biology, Faculty of Medicine, University of Indonesia

Title of qualification awarded Participant Principal

subjects/occupational skills covered

1st _{BASE DNA Sequencing Data Analysis Seminar} - DNA Sequencing Data Analysis

- Best Practice in Sample Preparation Name and type of

organisation providing education and training

1st _{BASE and PT. Genetika Science}

PERSONAL SKILLS AND COMPETENCES

Mother tongue INDONESIAN

Other language English

• Writing Skills Excellent • Reading Skills Excellent

• Verbal Skills Excellent

SOCIAL SKILLS AND COMPETENCES

ƒ Excellent ability of communication and teamwork especially developed during my job at the Cancer Chemoprevention Research Center, Faculty of Pharmacy, Gadjah Mada University and JICA Project where I often worked with other people.

ƒ Became an apprentice student at Quality Assurance Division of Glaxo Smith Kline Indonesia motivate me to learn fast and quickly adapt to new environment, which is very different with academic situation that I used to be experienced before.

ƒ Since I was a student, I am highly motivated to be the best, which is proved from my GPA that are above the average level.

ORGANISATIONAL SKILLS AND COMPETENCES

During my job at the Cancer Chemoprevention Research Center, Faculty of Pharmacy, Gadjah Mada University and JICA Project, I used to coordinate team of researcher and students thus developing a good experience in the

administration of people.

COMPUTER SKILLS AND COMPETENCES

ƒ Good knowledge of Microsoft Windows and Machintosh.

ƒ Good knowledge of Microsoft Word, Excel, and Powerpoint.

ƒ Good knowledge of Graphic Design Program (CorelDraw, Adobe Photoshop)

ƒ Excellent ability in navigation through the Internet.

RESEARCH SKILLS AND COMPETENCES

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While during my working experinces as a research assistant in JICA project on Identification of Anti-Hepatitis C Virus (HCV) Substances and Development of HCV and Dengue Vaccine, my research skills has been improved rapidly. I’ve conducted anti-HCV activity of plant extracts by virus titration experiment and immunostaining method. In this project, I propagated HCV virus in hepatocarcinoma cells (Huh7 it-1). I also cloned virus gene into bacteria, purified DNA/plasmid, transcripted DNA into RNA (RNA in vitro transcription), and transfected RNA into mammalian cells. I amplified virus gene with PCR method and did sequence DNA analysis to know that I’ve already get the correct DNA sequences.

DRIVING LICENCE I am a holder of an Indonesian drivers licence. Category A and C vehicle.

ADDITIONAL INFORMATION RESEARCH EXPERIENCES

ƒ Proliferative Effect of Ethanolic Extract of Long Bean on Breast Cell (2006)

ƒ The Potency Study of Curcumin and Its Analogues as Selective Estrogen Receptor Modulators (SERMs): Docking to Estrogen Receptors β (2006)

ƒ Ethanolic Extract and Ethyl Acetate Fraction Effect of Long Bean (Vigna cylindrica (L.) Skeels) on The Increase of Estrogen Receptor Expression in Breast Epithelial Cell (2007)

ƒ The Use of Local Mandarin Orange (Citrus reticulata) Peel Extracts to Increase Sensitization of Breast Cancer Cells MCF-7 against Chemotherapeutic Agent Doxorubicin (2007)

ƒ Modulation of Cell Cycle and Apoptotic Induction by Pentagamavunon-0 and Doxorubicin Combination Toward MCF-7 Breast Cancer Cell (2008)

ƒ The Increase of Doxorubicin Cytotoxic Activity by Citrus Flavonoid, Tangeretin on Breast Cancer Cells MCF-7 (2009)

ƒ Tangeretin Increase Doxorubicin Cytotoxic Activity on Breast Cancer Cells T47D (2009)

ƒ Cytotoxic Effect of Awar-Awar (Ficus Septica Burm F.) Leaves Ethanolic Extract on Colon Cancer WiDr and Servix Cancer HeLa (2009)

ƒ Induction of Apoptosis and Cell Cycle Arrest by Naringenin to Increase The Cytotoxic Activity of Doxorubicin on Breast Cancer Cell Lines (2009)

ƒ Hesperidin Increase Cytotoxic Effect of Doxorubicin in MCF-7 and T47D Cells (2009)

ƒ The Improvement of Doxorubicin Activity by Etanolic Extract of Citrus Aurantifolia Peel on MCF-7 Breast Cancer Cell through the Induction of Cell Cycle Arrest and Apoptosis (2009)

ƒ Combination of Awar-Awar (Ficus Septica Burm F.) Leaves Ethanolic Extract and Doxorubicin Gives Synergistic Effect In T47D Cells (2009)

ƒ Identification of Anti-Hepatitis C Virus (HCV) Substances and Development of HCV and Dengue Vaccine (2010-2011)

PUBLICATIONS

ƒ Fitriasari A, Wijayanti NK, Fitriyah NQ, Dewi IP, Mayasari MP, and Meiyanto

E, Proliferative Effect of Ethanolic Extract of Long Bean on T47 D Cell, PHARMACON, Vol. 8, No. 2, Desember 2007, 44-50.

ƒ Yunas SR, Latifah N, Rokhman MR, Fitriasari A, Putri DA, and Meiyanto E, Ethanolic Extract of Mandarin Orange (Citrus Reticutata) Peels to Incerase The Sensitivity of MCF-7 Breast Cancer Cell to Doxorubicin, PHARMACON, Vol. 8, No. 2, Desember 2007, 64-69.

and Meiyanto E, Selective Estrogen Receptor Modulators (SERMs) Potency of Curcumin and Its Analogues : Docking to Estrogen β Receptors,

PHARMACON, Vol. 9, No. 1, June 2008, 27-32.

ƒ Fitriasari A, Susidarti RA, and Meiyanto E, Peningkatan Efek Sitotoksik

Doxorubicin oleh Naringenin Melalui Pemacuan Apoptosis Sel Kanker Payudara MCF-7, Jurnal Bahan Alam Indonesia, Vol. 7, No. 3, 2010, 165-170.

ƒ Pratama RH, Ikhtiarsyah YG, Anindyajati, Fitriasari A, Ikawati M, dan Meiyanto E, Ekstrak Etanolik Daun Awar-Awar (Ficus septica Burm F.) secara Sinergis Meningkatkan Efektivitas Doxorubicin terhadap Sel Kanker Payudara T47D, Jurnal Ilmu Kefarmasian Indonesia, Vol. 9, No. 1, April 2011, 67-71.

ƒ Meiyanto E, Hermawan A, Junedi S, Fitriasari A, and Susidarti RA, Nobiletin Increased Cytotoxic Activity of Doxorubicin on MCF-7 Cells But Not on T47D Cells, International Journal of Phytomedicine, Vol. 3, No. 1, 2011, 129-137.

ƒ Meiyanto E, Fitriasari A, Hermawan A, Junedi S, and Susidarti RA, The Improvement of Doxorubicin Activity on Breast Cancer Cell Lines by Tangeretin through Cell Cycle Modulation, Oriental Pharmacy and Experimental Medicine, Vol. 11, published online 5 July 2011.

REFERENCES

ƒ Prof. Edy Meiyanto, PhD, Pharmacist, Head of Cancer Chemoprevention Research Center, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia. Address : Sekip Utara, Yogyakarta. E-mail : meiyan_e@ugm.ac.id. Tel (+62) 8122735092.

ƒ Dr. Ratna Asmah Susidarti, Pharmacist, Head of Chemical Pharmacy Department, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia. Address : Sekip Utara, Yogyakarta. E-mail : susidarti@yahooo.com Tel (+62) 81328770163.

I hereby agree to the handling of my personal data.