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AD Auto disable

AEFI Adverse events following immunization

AFP Acute flaccid paralysis

BCG Bacillus Calmette-Guérin vaccine

CES Coverage evaluation survey

cMYP Comprehensive multi-year plan

CRS Congenital rubella syndrome

DHS Demographic health survey

DT Diphtheria tetanus toxoid, pediatric

DTP Diphtheria – tetanus – pertussis vaccine

DTP3 3rd dose DTP

DTP-Hib-HepB Pentavalent vaccine

DTP-Hib-HepB3 3rd dose pentavalent vaccine

EPI Expanded Programme on Immunization

GDP Gross domestic product

HCW Health care worker

HepB Hepatitis B vaccine

HepB3 3rd dose HepB

Hib Haemophilus influenzae type B vaccine

HPV Human papilloma virus vaccine

IgM Immunoglobulin M

IPV Inactivated poliovirus vaccine

JE Japanese encephalitis

JE_Live-Atd JE live attenuated vaccine

JRF WHO UNICEF Joint Reporting Form

LB Live birth

M Measles

Acronyms

MCV1 First dose MCV

MCV2 Second dose MCV

MICS Multiple indicator cluster survey

MMR Measles mumps rubella vaccine

MNT Maternal and neonatal tetanus

MR Measles rubella vaccine

NCIP National committee on immunization practices

NID National immunization day

NTAGI National technical advisory group on immunization

NT Neonatal tetanus

OPV Oral poliovirus vaccine

OPV3 3rd dose OPV

bOPV Bivalent OPV

tOPV Trivalent OPV

PCV Pneumococcal conjugate vaccine

SEAR WHO South-East Asia Region

SEARO WHO South-East Asia Regional Office

SIA Supplementary immunization activities

SNID Subnational immunization day

Td Tetanus diphtheria toxoid; older children, adults

TT Tetanus toxoid

TT2+ 2 or more doses TT

VDPV Vaccine derived poliovirus

VPD Vaccine preventable diseases

WCBA Women of child bearing age

(4)

Contents

WHO South-East Asia Region

Maternal and neonatal tetanus elimina�on is sustained

Page

No.

TT2+ coverage by country, 2012-2016 Figure 9 13

MNT eliminaion status Figure 10 13

Regional demographic atributes

Page

No.

SEAR populaion density by irst administraive level Figure 1 5

Basic informaion, 2016 Table 1 6

Rou�ne immuniza�on systems and services

Page

No.

Rouine immunizaion schedules by country, 2016 Table 2 7

BCG, DPT3, OPV3, MCV1, MCV2, HepB 3 and RCV coverage in SEAR, 2000-2016 Figure 2 8

Rouine immunizaion coverage esimates, 2012-2016 Table 3 9

Planning and management indicators, 2016 Table 4 10

Vaccine safety, 2016 Table 5 10

Reported vaccine preventable diseases, 2014-2016 Table 6 11 DTP3 coverage by country, 2012-2016 Figure 3 12 Districts achieving >80% DTP3 coverage by country, 2012-2016 Figure 4 12 DTP1-DTP3 drop-out by country, 2012-2016 Figure 5 12

DTP3 immunizaion coverage by irst administraive level, 2016 Figure 6 12

The Immunizaion and Vaccine Development (IVD) unit of the Department of Family Health, Gender and Life Course (FGL), World Health Organizaion (WHO), Regional Oice

for South-East Asia (SEARO) has been producing annually the Expanded Programme on Immunizaion (EPI) fact sheets since 2002 for all SEA countries and the region. The

primary data source of the EPI fact sheets are the WHO-UNICEF joint reporing form (JRF) and SEARO annual EPI reporing form (AERF) in which each country oicially reports

EPI and vaccine preventable diseases (VPD) related core informaion annually. The EPI factsheets 2017 are based on 2016 data reported to WHO SEARO by the Member States.

Polio-free status is maintained

Page

No.

NID/SNID and date of last WPV conirmed cases, 1995-2016 by country Table 7 14

Last WPV conirmed cases by type in SEAR Figure 11 14

Environmental surveillance for poliovirus detecion, 2014-2016 Table 8 14

AFP surveillance indicators by country, 2014-2016 Table 9 15

AFP surveillance indicators by irst administraive level, 2016 Figure 12 15

Towards measles elimina�on and rubella/congenital rubella

syndrome control

Page

No.

MCV1 coverage by country, 2012-2016 Figure 13 16 Status of sub-naional coverage for 1st dose of measles and

rubella containing vaccine in the SEA Region, 2016 Figure 14 16

Rubella vaccine introducion through rouine immunizaion Figure 15 16

Suspected measles cases and outbreaks by country, 2016 Table 10 17 Measles and rubella laboratory surveillance indicators, 2016 Table 11 18 Network of WHO supported laboratories for VPD surveillance in SEAR Figure 16 19

Control of Hepa��s B is accelerated

Page

No.

HepB3 coverage, 2012-2016 Figure 7 13

(5)

Regional demographic attributes

*Populaion density by second administraion level for Bhutan, Sri Lanka and Timor-Leste.

Figure 1:

SEAR population density by first administrative level*

Disclaimer: The boundaries and names shown and the designaions used on all the maps do not

(6)

Table 1:

Basic information, 2016

Country

2016 popula�on

1

Mortality

2

Administra�ve levels

1

Total

popula�on

Live births

Children

< 1 year

< 5 years

Children

< 15 years

Children

Neonatal

mortality rate

(per 1000 LB)

Infant

mortality rate

(per 1000 LB)

Under ive

mortality rate

(per 1000 LB)

Maternal

mortality

ra�o (per

100000 LB)

Number of

provinces /

regions /

India

1,300,000,000 27,005,535 26,008,988 121,400,000 400,700,000 27.7 37.9 47.7 174 36 676

Indonesia

258,704,986 4,858,600 4,760,891 23,960,310 70,096,861 13.5 22.8 27.2 126 34 514a

1 SEAR annual EPI reporing form, 2016 2 WHO, World Health Staisics ,2016

(7)

Table 2:

Routine immunization schedules by country, 2016

Country

BCG

DTP

HepB

MCV

OPV

TT

Vitamin A

Other vaccina�ons

Bangladesh

At birth DTPHibHepB - 6W, 10W, 14W MR-38W, 15M 6W, 10W, 14W IPV-14W

Females 15Y to 49Y (5 doses with an

interval of + 1 month, + 6 months, + 1 year

and + 1 year with preceding dose)

6-59M

(not given

through EPI) PCV- 6W, 10W, 18W

Bhutan

At birth

HepB- At birth

DTPHibHepB- 6W, 10W, 14W DTP- 24M

MMR- 9M, 24M At birth, 6W, 10W, 14W

IPV-14W Td- 6Y, 12Y 6-30M HPV- Girls 12Y & Grade VI students

DPR Korea

At birth HepB- At birth

DTPHibHepB - 6W, 10W, 14W

Measles-9M, 15M

6W, 10W, 14W

IPV-14W Td - 3M, 4M of pregnancy 6-59M

-India

At birth

HepB - At birth

DTPHibHepB - 6W, 10W, 14W DTP - 16-24M, 5Y

IPV- 6W, 14W (as fracional dose)

10Y and 16Y, 2 doses/booster for pregnant women

9 months, 18 months and 6 months

interval ill

age 5 years

JE_LiveAtd - 9M and 16-24M (JE endemic districts)

PCV - (Apr 2017, upto 1Y, subnaional) Rotavirus-6W,10W,14W (…..2017, upto 1 year, subnaional)

Indonesia

1M HepB- 0-7 days of birth DTPHibHepB - 2M, 3M, 4M, 18M

Measles-9M,

Maldives

At birth HepB-At birth

DTPHibHepB - 2M, 4M, 6M

Measles-9M MMR - 18M

2M, 4M, 6M (+15Y pilgrims)

IPV-6M Td - Females 15Y (+1M, +6M, +1Y, +1Y) 9-59M

Men ACWY- +15Y pilgrims YF- +15Y travelers

Myanmar

Birth to 2M HepB- At birth

DTPHibHepB- 2M, 4M, 6M

MR- 9M Measles- 18M

2M, 4M, 6M IPV- 4M

First contact during pregnancy and 4 weeks

later 6-59M

-Nepal

At birth DTPHibHepB - 6W, 10W, 14W MR-9M, 15M 6W, 10W, 14W

IPV-14W Td- First contact pregnancy, +1M 6-59M, +6M

JE_LiveAtd - 12M (high-risk districts)

PCV- 6W, 10W, 9M

Sri Lanka

At birth DTPHibHepB - 2M, 4M, 6M

DTP - 18M MMR - 9M, 3Y

2M, 4M, 6M, 18M, 5Y

IPV- 2M, 4M (as fracional dose)

DT - 5Y

Td - 12Y (grade 7)

TT - Pregnant women (2 doses in 1st

pregnancy and 1 dose in subsequent 3

pregnancies)

6-36M JE_LivteAtd - 1Y

Typhoid - high risk groups

Thailand

At birth

HepB - At birth, 1M (new-born from HepB carrier mother)

DTPHepB - 2M, 4M, 6M

DTP - 1.5Y, 4Y

MMR - 9M, 2.5Y 2M, 4M, 6M, 1.5Y, 4YIPV-4M Td- 12Y (grade 6), Pregnant women 1st contact, +1M, +6M (depending on vaccinaion history)

-JE_LiveAtd- 1.5Y, 2.5Y (29 provinces) JE_Inactd - 1.5Y (2 doses 1M apart), 2.5Y Rotavirus- 2m, 4M (pilot in selected provinces)

HPV- females at grade 5 and grade 6

(pilot in selected provinces)

Timor-Leste

At Birth

HepB- At birth (Feb 2016)

DTPHibHepBIPV- 6W, 10W, 14W

DPT-18M MR-9M, 18 M

Birth, 6W, 10W, 14W IPV-14W

Females 15Y-49Y (1st pregnancy contact, +1M, +6M, +1Y, +1Y)

DT- 6Y

6-36M (6M interval)

-Source: WHO/UNICEF JRF 2016 W=Week M=Month Y=Year

Routine immunization systems and services

(8)

Source: WHO/UNICEF esimates of naional immunizaion coverage, July 2017 revision

BCG DPT3 OPV3 MCV1 MCV2 HepB3 RCV

(9)

Table 3:

Routine immunization coverage estimates, 2012-2016

Country

BCG

DTP3

OPV3

MCV1

2012

2013

2014

2015

2016

2012

2013

2014

2015

2016

2012

2013

2014

2015

2016

2012

2013

2014

2015

2016

Bangladesh

98 99 99 99 99 94 96 97 97 97 94 96 97 97 97 88 91 94 94 94

Bhutan

95 97 99 99 99 97 97 99 99 98 97 97 98 98 97 95 94 97 97 97

DPR Korea

98 98 98 97 97 96 93 93 96 96 99 99 99 99 99 99 99 99 98 99

India

90 91 89 87 89 82 83 85 87 88 79 82 84 86 86 83 83 85 87 88

Indonesia

88 86 82 80 81 83 85 78 78 79 84 86 80 80 80 82 81 75 75 76

Maldives

99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 98 99 99 99 99

Myanmar

87 86 92 94 88 84 75 88 89 90 87 76 88 89 89 84 86 88 84 91

Nepal

96 97 99 94 93 90 92 92 91 87 90 92 92 90 85 86 88 88 85 83

Sri Lanka

99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 99

Thailand

99 99 99 99 99 99 99 99 99 99 99 99 99 99 99 98 99 99 99 99

Timor-Leste

86 86 84 84 85 83 82 77 76 85 83 82 76 75 83 73 70 74 70 78

SEAR

91 91 90 88 89 84 85 86 87 88 82 84 85 87 87 84 84 85 86 87

(10)

Table 4:

Planning and management indicators, 2016

Spending on r

ou�ne

Bangladesh

2014-2018 fully

funcional 27% 29% 64 districts (100%) EPI CES 2015

Bhutan

2014-2018 fully

funcional 41% 24% 20 districts (100%) Naional Health Survey, 2012

DPR Korea

2016-2020 fully

funcional datano no data

210 districts

(100%) CES and MICS

India

2013-2017 funcionalfully 50% 56% 676 districts

(100%) Naional Family Health Survey-4 2015

Indonesia

2015-2019 fully

funcional 90% 88% ND

Basic Health Survey 2013, District Coverage Survey

in 10 provinces and 31 districts 2015

Maldives

2016-2020 fully

funcional 100% 72% 20 atolls (100%) DHS ongoing

Myanmar

2017 -2021 funcionalfully 6% 24% ND Demographic and Health Survey 2015-2016

Nepal

2011-2016 funcionalfully 22% 24% 75 districts (100%) Demographic Health Survey 2016

Sri Lanka

2017-2021 funcionalfully no

data 74%

26 districts

(100%) Nuwara Eliya district 2016EPI coverage survey

Thailand

2012-2016 fully

funcional datano no data

77 provinces

(100%) based immunizaion 2013CES for basic and

school-Timor-Leste

2016-2020 fully

funcional 76% 39% 13 districts (100%)

EPI CES Dili municipality and 12 other municipaliies 2015

Source: WHO/UNICEF JRF, 2016 ND: no data

Table 5:

Vaccine safety, 2016

Country

Adverse events following immuniza�on (AEFI)

Na�onal system

to monitor AEFI

Reported

No. AEFI

Of the total adverse

events reported no. of

serious

Bangladesh

Yes 2,563 54

Bhutan

Yes ND 9

DPR Korea

Yes -

-India

Yes 1,393 1280

Indonesia

Yes 11,832 112

Maldives

Yes 2 0

Myanmar

Yes 63 10

Nepal

Yes 1,684 34

Sri Lanka

1 Yes 9,389 225

Thailand

Yes 751 0

Timor-Leste

Yes ND 0

Source: WHO/UNICEF JRF, 2016

(11)

Table 6:

Reported vaccine preventable diseases, 2014-2016

Country

2014

2015

2016

P

tanus (NT)

Measles

Rubella

Mump

s

tanus (NT)

Measles

Rubella

Mump

s

tanus (NT)

Measles

Rubella

Mump

s

(492) 26,530 5,716 0 1,657 0b 2,365 25,206 2,268 (491) 30,168 5,850 ND 1,620 0d 3,380 37,274 3,781 (227) 17,250 10,311 ND 1,627

Indonesia

0 430 2,082 1,023

(75) 12,943 3,542 ND 72 0 252 1,004

(57) 1,279 704 34,034 1,304 0 236 4,416 (266)888 1,599 626 38,858 937 0 140 4,890 766 (7) 1,269 656 30,610 98

Sri Lanka

0 0 38 9 (0) 1,686 10 383 21 0 0 107 15 (0) 1,568 9 ND 17 0 0 54 5(0) 112 0 311 18

Thailand

0 19 14 81 (2) 146 152 3,704 31 0 19 51 0 154 240 3,121 23 0 16 84 61 (0) 652 7 23 21

Timor-Leste

0 2 0 0 47 1 0 0 0 1 5 0 48 5 ND 0 0 0 6 0 2 8 0 1

SEAR

0 7,666 54,953 6,126 (658) 43,045 10,536 38,327 3,320 0 2,966 30,817 3,730 (933) 43,657 7,783 42,599 2,830 0 4,016 43,141 5,250 (366) 27,530 12,398 31,739 3,500 a Excludes 3 VPDVs (type 2) b Excludes 2 VDPVs (type 2) c Excludes 2 cVDPVs (type 2) d Excludes 1 VDPV (Type 2)

(12)

Figure 3:

DTP3 coverage by country, 2012-2016

Source: WHO/UNICEF esimates of naional immunizaion coverage, July 2017 revision

Figure 4:

Districts achieving >80% DTP3 coverage

by country, 2012-2016

0

Source: WHO/UNICEF JRF , 2017 * data from province level

Figure 5:

DTP1-DTP3 drop-out by country, 2012-2016

2016

Source: WHO/UNICEF esimates of naional immunizaion coverage, July 2017 revision

Figure 6:

DTP3 immunization coverage by

first administrative level*, 2016

*Thailand, Bhutan, Maldives & Timor-Leste by country Source: SEAR AERF 2016

(13)

Eliminated from 2000 – May 2016 Eliminated before 2000

DTP-Hib-HepB (Pentavalent)

DTP-HepB Tetra/Mono HepB

Figure 7:

HepB vaccine and HepB3 coverage, 2016

Country

HepB3 coverage

2012

2013

2014

2015

2016

Bangladesh

94 96 97 97 97

Bhutan

97 97 99 99 98

DPR Korea

96 93 93 96 96

India

73 70 79 87 88

Indonesia

83 85 78 78 79

Maldives

99 99 99 99 99

Myanmar

58 75 88 89 90

Nepal

90 92 92 91 87

Sri Lanka

99 99 99 99 99

Thailand

98 99 99 99 99

Timor-Leste

83 82 77 76 85

SEAR

77 76 82 87 88

Source: WHO/UNICEF esimates of naional immunizaion coverage, July 2017 revision

Maternal and neonatal tetanus elimination is sustained

Figure 9:

TT2+ coverage by country, 2012-2016

Figure 10:

MNT elimination status

2016

Source: WHO/UNICEF JRF, Country oicial esimates, 2012-2016

Control of Hepatitis B is accelerated

(14)

WPV type 2, U�ar Pradesh, India, 1999

WPV type 3, Jharkhand, India, 2010

WPV type 1, West Bengal, India, 2011

Table 7:

NID/SNID and date of last WPV confirmed cases, 1995-2016 by country

Polio-free status is maintained

Country

Year of 1st NID

Total NID rounds

Last NID round

SNIDs in 2016

Last WPV conirmed case

Bangladesh

1995 40 Dec-13 Yes 22-Nov-06

Bhutan

1995 2 Nov-95 No 1986*

DPR Korea

1997 12 Nov-02 No 1996

India

1995 41 Feb-16 Yes 13-Jan-11

Indonesia

1995 14 Mar-16 Yes 20-Feb-06

Maldives

1996 8 Jan-01 No 1994

Myanmar

1996 23 Feb-16 Yes 28-May-07

Nepal

1996 27 Jan-14 Yes 30-Aug-10

Sri Lanka

1995 8 Dec-00 No Nov-93

Thailand

1994 10 Jan-00 No Apr-97

Timor-Leste

1995** 11 Aug-15 No 1995

* Clinically conirmed polio ** SIA conducted with Indonesia.

Figure 11:

Last WPV confirmed cases by type in SEAR

Table 8:

Environmental surveillance for poliovirus detection, 2014-2016

Country

2014

2015

2016

Number

of samples

collect

ed

Number

of samples

collect

ed

Number

of samples

collect

ed

(15)

Country

2014

2015

2016

AFP

Adequate stool specimen collec�on

percentageb

Adequate stool specimen collec�on

percentageb

Adequate stool specimen collec�on

percentageb

a Number of discarded AFP cases per 100,000 children under 15 years of age. b Percent with 2 specimens, 24 hours apart and within 14 days of paralysis onset. 1 Excludes twelve type 2 VDPV specimens from sewage 2 Excludes eleven type 2 VDPV specimens from sewage 3 Excludes six type 2 VDPV specimens from sewage

Figure 12:

AFP surveillance indicators by first administrative level

1

, 2016

Non-polio AFP rate*

% Adequate Stool Specimen Collection**

*Number of discarded AFP cases per 100,000 children under 15 years of age.

**Percentage with 2 specimens collected at least 24 hours apart and within 14 days of paralysis onset

1 Bhutan, Maldives & Timor-Leste by Country <1 1 – 1.99

>2 No non-polio AFP case

(16)

Planned in 2018 2017 2015 <=2013

Figure 13:

MCV1 coverage by country, 2012-2016

Figure 14:

Status of sub-national coverage for 1st dose of measles

and rubella containing vaccine in the SEA Region, 2016

Source: WHO/UNICEF esimates of naional immunizaion coverage, July 2017 revision

Towards measles elimination and rubella/CRS control

2016

>95% 80%-94% <80% 0

Figure 15:

Rubella vaccine introduction through routine immunization

(17)

Table 10:

Suspected measles cases and outbreaks by country, 2016

Country

No. of Suspect

ed Measles

Case classiica�on (number)

Indicators

Measles

Rubella

Annual incidence of

con

irmed measles c

ases per

million t

ot

al popula

�on

Annual incidence of

con

irmed rubella c

ases per

opor�on of all suspect

ed

measles and rubella c

ases

tha

t ha

ve had an adequa

te

in

ves

�g

a�on ini�a

ted within

48 hour

s of no�ic

a�on

Non-measles non-rubella

disc

ar

opor�on of sur

veillance

units r

epor�ng on �me

Serum

conirmed

linked

EPI-

Clinically-conirmed

conirmed

Lab-

linked

EPI-

No.

%

No.

%

Bangladesh

4,289 618 354 81 165 0 3,060 6.05 1.03 94% 1.90 97% 3,729 87% 522 12%

Bhutan

146 45 0 0 3 0 106 53.00 4.00 NA 14.00 NA 146 100% NA NA

DPR Korea

73 0 0 0 0 0 73 0.00 0.00 100% 0.32 96% 73 100% 46 63%

India

36,447 3,476 13,070 704 1,351 8,960 4,107 13.10 7.80 16% 0.50 90% 7,763 11% 772 1%

Indonesia

14,011 2,541 NA 5,495 1,193 NA 2,474 9.82 4.61 NA 0.96 NA 8,516 61% NA NA

Maldives

12 0 0 0 0 0 12 0.00 0.00 100% 2.98 12% 12 100% 0 0%

Source: SEAR annual EPI reporing form, 2016

(18)

Table 11:

Measles and rubella laboratory surveillance indicators, 2016

Country

SEROLOGY

VIROLOGY

Tot

al serum specimen

receiv

ed in labor

at

or

y

Specimens

received

cases tested

for serology

Specimen

posi�ve for

measles

IgM

Specimen

posi�ve for

rubella IgM

of receiving

the specimen

for serology

Tot

al vir

ology specimen

receiv

ed in labor

at

or

y

Specimen

posi�ve for

measles

virology

Specimen

posi�ve

for rubella

virology

Results

reported by

the laboratory

within 2

months of

receiving the

specimen for

virology

India

7,763 7,763 100% 7,763 100% 3,476 45% 1,351 17% 3,497 56% 772 281 36% 36 5% 463 60% D4,D8,B3 2B

Indonesia

15,939 ND ND 12,064 76% 4,946 41% 1,899 16% 6,835 57% 208 16 8% ND ND ND ND ND ND

*this includes 5 rubella Igm posiive samples that were subsequently excluded as they are post vaccinaion and one sample that was a repeat sample

(19)

Polio (Global specialized) Measles and Rubella

Japanese Encephaliis

IBD reference Rota reference Reference labs

Measles and Rubella Japanese encephaliis Polio

IBD Rota

Na�onal labs

Sub-national measles lab

(20)

For contact or feedback:

Immunizaion and Vaccine Development (IVD), Department of Family Health, Gender and Life Course (FGL)

Gambar

Figure 1: SEAR population density by first administrative level*
Table 1: Basic information, 2016
Table 2: Routine immunization schedules by country, 2016
Figure 2: BCG, DPT3, OPV3, MCV1, MCV2, HepB 3 and RCV coverage in SEAR, 2000-2016
+7

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