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Naidech, A. (2020). Natural History of Infratentorial Intracerebral Hemorrhages: Two Subgroups with Distinct Presentations and Outcomes. Journal of Stroke and Cerebrovascular Diseases, 29(8), 104920.

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21. Spiegler, S., Rath, M., Paperlein, C., & Felbor, U. (2018). Cerebral Cavernous Malformations: An Update on Prevalence, Molecular Genetic Analyses, and Genetic Counselling. Molecular syndromology, 9(2), 60-69.

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27. Tschoe, C., Bushnell C. D., Duncan P. W., Miller M. A. A., Wolfe S.

Q. (2020). Neuroinflammation After Intracerebral Hemorrhage and Potential Therapeutic Targets. Journal of Stroke, 22(1), 29-46.

28. Liu, D. Z., & Sharp, F. R. (2011). The Dual Role of SRC Kinases in Intracerebral Hemorrhage. Intracerebral Hemorrhage Research, 77- 81.

29. Wan, S., Cheng, Y., Jin, H., Guo, D., Hua, Y., Keep, R. F., & Xi, G.

(2016). Microglia Activation and Polarization After Intracerebral Hemorrhage in Mice: The Role of Protease-Activated Receptor- 1. Translational stroke research, 7(6), 478-487.

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45. Wang, F., Wang, L., Jiang, T. T., Xia, J. J., Xu, F., Shen, L. J., ... &

Wu, X. (2018). Neutrophil-to-lymphocyte ratio is an independent predictor of 30-day mortality of intracerebral hemorrhage patients: a

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46. Qdaisat, A., Yeung, S. C. J., Rojas Hernandez, C. H., Samudrala, P., Kamal, M., Li, Z., & Wechsler, A. H. (2022). Characteristics and Outcomes of Intracranial Hemorrhage in Cancer Patients Visiting the Emergency Department. Journal of Clinical Medicine, 11(3), 643.

47. Shao, Z., Tu, S., & Shao, A. (2019). Pathophysiological mechanisms and potential therapeutic targets in intracerebral hemorrhage. Frontiers in pharmacology, 10, 1079.

48. Zheng, H., Chen, C., Zhang, J., & Hu, Z. (2016). Mechanism and therapy of brain edema after intracerebral hemorrhage. Cerebrovascular diseases, 42(3-4), 155-169.

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Lampiran 1.

Skor ICH

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Lampiran 2.

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JL.PERINTIS KEMERDEKAAN KAMPUs TAMALANREA. KM"iO MAKASSAR. 90245"

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Conta6 Person: dr. Agussalim Bukhari.,MMed.PhD,SpGK TELP. OBI24IB5O85B, O4ll 5780103' Fax I O4l1-581431

REKOMENDASI PERSETUJUAN ETTK ]:1,;rt;,r: .', jtr'i1,.:.i.i,..i _-,.1 1,' pi:lir,' :ii:--

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Iudul Peneliti ^RASIONEUTROFIL-LIMFOSIT [RNL) DAN PLATELET COUNT IPCJ SEBAGAI MARKHR PR*GNOSTIK UNTUK }\'IORTAI"ITAS STROKE HEM*RAGIK ; S?UDI R"ETRSSPEKTIF 3 SEMESTER.

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Sekretaris ^KEP Universitas Hasanuddin

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Kewaiiban Peneiiti Utama:

* Menyerairkan Amanriernen Protokoi untuk persetujuan sebeltlnt di impiernentasikan

r Menyerahkan Laporan SAE ke Komisi Etik dalam 24 _Jamdan diiengkapi dalam 7 hari dan Lapor SUSAR dalam 72

|am setelah Peneliti Lltama menerima laporan

* Ivlenyerahkan Lap*ralr ]i{ernajuan {progress report} setiap 6 i:ulan untuk perie}itian resiko ^tiraggidait ^setiap setahun untuk penelitian resiko rendah

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o Melaporl<an penyimpangan clari prckol yang disetujtli {protocci rieviation _r/viciatianl

r Mematuhi semua peraturan yang ditentukan

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Lampiran 3.

Uji Normalitas Data RNL

Kolmogorov-Smirnov test Meninggal Hidup

KS distance 0,1645 0,1197

P value 0,0031 0,0028

Passed normality test (alpha=0.05)? No No

P value summary ** **

Uji Normalitas Data PC

Kolmogorov-Smirnov test Meninggal Hidup

KS distance 0,1701 0,06612

P value 0,0019 >0,1000

Passed normality test (alpha=0.05)? No Yes

P value summary ** ns

Perbandingan RNL pasien hidup dan meninggal

Mann-Whitney test

P value 0,0008

Exact or approximate P value? Exact

P value summary ***

Significantly different (P < 0.05)? Yes

One- or two-tailed P value? Two-tailed

Sum of ranks in column A,B 3870 , 5446

Mann-Whitney U 1351

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Perbandingan PC pasien hidup dan meninggal

Mann-Whitney test

P value <0,0001

Exact or approximate P value? Exact

P value summary ****

Significantly different (P < 0.05)? Yes

One- or two-tailed P value? Two-tailed

Sum of ranks in column A,B 2211 , 7105

Mann-Whitney U 1130