TESIS
Disusun untuk Memenuhi Sebagian Persyaratan Mencapai Derajat Magister Program Studi Kedokteran Keluarga
Oleh :
Igor Hermando
S 501108043
PROGRAM PASCASARJANA
UNIVERSITAS SEBELAS MARET
SURAKARTA
2015
HUBUNGAN
PULSE PRESSURE DAN USIA DENGAN OUTCOME
PADA PASIEN STROKE ISKEMIK FASE AKUT
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ÜßÚÌßÎ Í×ÒÙÕßÌßÒ
ßÜÑ æ ß´·®¿² Ü¿®¿¸ Ѭ¿µ
ßÜÐ æAdenosine Diphosphate
ßØßñßÍß æ American Heart Association / American Stroke Association
ßÌÐ æAdenosine Triphosphate
ÝÞÚ æCerebral Blood Flow
ÝÌ Í½¿² æComputed Tomography Scan
ÝÊÜ æCerebrovascular Disease ø°»²§¿µ·¬ -»®»¾®±ª¿-µ«´»®÷
ÜÒß æDeoxyribonucleic Acid ø¿-¿³ ¼»±µ-·®·¾±²«µ´»¿¬÷
ÛÕÙ æ Û´»µ¬®±µ¿®¼·±¹®¿º·
ÛËÍ× æEuropean Union Stroke Initiative
ÙÝÍ æGlasgow Coma Scale
Ò×ØÍÍ æNational Institutes of Health Stroke Scale
ÒÓÜß : N-Methyl-D-Aspartat
ÐßÝ× æPartial Anterior Circulation Infarct ø·²º¿®µ -·®µ«´¿-· ¿²¬»®·±® °¿®-·¿´÷
Ð×Í æ л®¼¿®¿¸¿² ײ¬®¿-»®»¾®¿´
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ÐÑÝ× æPosterior Circulation Infarct ø·²º¿®µ -·®µ«´¿-· °±-¬»®·±®÷
ÐÐ æPulse Pressure
ÐÍß æ л®¼¿®¿¸¿² Í«¾¿®¿µ²±·¼
ÍÞÐ æSystolic Blood Pressureø¬»µ¿²¿² ¼¿®¿¸ -·-¬±´·µ÷
ÍÜÞ æStroke Data Bank
ÍÜÑ æ Í¿©¿® Ü¿®¿¸ Ѭ¿µ
ÌßÝ× æTotal Anterior Circulation Infarct ø·²º¿®µ -·®µ«´¿-· ¿²¬»®·±® ¬±¬¿´÷
ÌÜÜ æ Ì»µ¿²¿² Ü¿®¿¸ Ü·¿-¬±´·µ
ÌÜÍ æ Ì»µ¿²¿² Ü¿®¿¸ Í·-¬±´·µ
Ì×ß æTransient Ischemic Attack
Ì×Õ æ Ì»µ¿²¿² ײ¬®¿µ®¿²·¿´
ÌÒÚ æTumor Necrosis Factor
ÌÐÑ æ Ì»µ¿²¿² л®º«-· Ѭ¿µ
ÊÉÚ æVon Willebrand Factor
¨ª· patients. One of the components of the blood pressure is pulse pressure (PP). PP is the difference between systolic blood pressure and diastolic. PP can be used to predict the outcome or improvement of neurological deficit in stroke patients because PP describes the stiffness of blood vessels. The use of PP in predicting outcome or neurological improvement of stroke patients still controversial because some previous studies showed contradictory results. An increasing in age has an independent relation with ischemic stroke outcome compared to haemorrhagic stroke. Researchers want to know the relation between PP and age with the outcome of acute phase ischemic stroke which further provide outcome predictor. We conducted cross sectional observational study using purposive sampling technique. The subjects were patients with acute ischemic stroke hospitalized at Dr. Moewardi Hospital. Fifty one subjects were included minimally based on calculation. The severity of stroke was assessed with NIHSS. Statistical analysis used linear regression with a confidence interval of 95%, a p-value < 0.05 was considered statistically significant. Research results obtained in the outcome of acute phase ischemic stroke significantly associated with pulse pressure and age where the value of p = < 0.05. Conclusion: There is meaningful relation between PP and age with the outcome of acute phase ischemic stroke.
