SCHOOL OF MEDICINE ., 103

princiJ?les of absorption, distribution, biotransformation, and elimination;

b) tOxicologic phenomena such as hepatoxicity of fluorinated agents, nephro- toxicity of methoxyflurane, convulsive activity, malignant hyperthermia, antibiotic-induced paralysis, oxygen toxicity, and other hazards of hyper- baric anesthesia, barbiturates and porphyria, ionic calcium disturbances, etc. Anesthesiology

^52.1.

One hour per week. PALL.

Dr. Piuin!,er.

561. CLRRKSlIIPIN CLINICAL PHARMACOLOGY.Fourth year. During the clerkship the students will evaluate patients with general problems in drug therapy, drug toxicity, and drug interactions. In addition, he will partici.

pate

¹⁰

the diagnosis and pharmacologic therapy of patients with hyper- tension. He will attend the hypertension cllOic and the seminars and rounds of the Clinical Pharmacolo~y Division. (Medicine 571 and Pedi- atrics 565). Full time, six-week UOltS.

Dr. Nits, Dr. Wilson, Dr. Oatu,

anJ

Staff.

581. RESEARCHFELLOWSlllPIN PHARMACOLOOY.Fourth year. The various areas of pharmacology including clinical pharmacology. Full time for twelve or eighteen weeks. PALL

^8<

SPRINO.

Staff.

598. Sm.IINAR IN NEUROBIOLOGY. (33u-33 I b) An interdepartmental seminar involving the departments of Pharmacology, Psychology, Psy.

chiatry, and Anatomy. The tOpics covered relate to etiology of menu]

illness, behavioral psychology, and mechanism of action of dru$s which are employed both as psychomimetic agents and psychotherapeutic agents.

One hour per week. PALL

^8<

SPRING. [I-I]

Staff.

(Not offered

1972./73.)

599. SEMINARIN PHARMACOLOGY. (Boa-Bob) Fourth year. Admission to course by arrangement. One hour per week. PALL

^8<

SPRINO. [I-I] Staff.

399. RESEARCH. Experimental and theoretical aspects of the mechanis~

⁰

action of chemical substances on cell, tissue, and organ function, especial!) in the following areas: cardiac pharmacology, cancer chemotherapy, anti metabolites as chemotherapeutic agents, metabolic fate of narcotic

^~D

tranquilizing drugs, design and synthesis of new molecules as posslbJ chemotherapeutic substances. PALL

^8<

SPRINO. Hours and credit

by at

rangement.

Staff.

Physiology

CHARLESRAWLINSONPARK, M.D.,

Profeuor of PhysiologJ and Chairman0/1&

Department

EARL W. SUTHERLAND,JR., M.D.,

Distinguished Profeuor of Physiology;Carl Inflf1tigator, American Heart Auociation

JOHN H. EXTON, M.B.,Ch.B., Ph.D.,

Profmor of Physiology; InvtJtigal

Howard Hughf1 Medical Institute

JOEL G. HARDMAN,Ph.D.,

Profeuor of PhysiologJ

H. C. MENo, M.D., Ph.D.,

Profmor of PhysiologJ

104 f

VANDERBILT UNIVERSITY

ANBH. PARK, Ph.D.,

Profeuor of Physiology

ROBBRT

L.

POST, M.D.,

Profeuor of Physiology

OscAR B. CROfFORD, JR., M.D.,

Auociate Profeuor of Physiology

R. J. Ho, Ph.D.,

Associate Profeuor of Physiology

TBTSUROKONO, Ph.D.,

Associate Profeuor of Physiology

DAVIDM. REGEN, Ph.D.,

Auociate Profeuor of Physiology

EDWARD J. BATTBRSBY,M.D.,

Auistant Profeuor of Physiology

IAN

M.

BURR, M.D.,

Assistant Professor of Physiology; Investigator, Howard Hughes Medical Institute

, D,

CORBIN, Ph. D.,

Auistant Profeuor of Physiology,' Investigator, Howard Hughes Medical ltwitute

. WILLIAM McLAIN, JR., M.D.,

Auistant Professor of Physiology

ANTHONYR. MBANS, Ph.D"

Auistant Professor of Physiology

SIMONPILKIS, Ph.D.,

Auistant Profeuor of Physiology,' Investigator, Howard Hughes Medical Institute

H1LIPW. FELTS, M.D.,

Instructor in Physiology

ROGBR

A.

JOHNSON, Ph.D.,

Instructor of Physiology

ICHAELCALDWELL, M.D.,

Research Associate in Physiology

IMOTHYM. CHAN, Ph. D.,

Research Auociate in Physiology

ROMASH. CLAUS, Ph.D.,

Research Auociate in Physiology

AVID

L.

GARBERS. Ph.D.,

Research Auociate in Physiology

WARDHILL,

Research Auociate ;'1 Physiology

TANLEYKBELY, Ph.D.,

Research Auociate in Physiology,' Visiting [,Ivestigator, Howard Hu.~hes Medical Institute

ARGARBTS. NBBLBTT. Ph.D.,

Research Auociate in Physiology

ICIIIHIKOOGUCIII, M.D.,

Research Auociate in Physiology

LBERTOTTBN, Dr.Med.,

Research Auociate in Physiology

UBNTBRScHULTZ, M.D.,

Research Auociate in Physiology

ROMAS SODBRLING, Ph.D.,

Research Associate in Physiology

RARLESA. SUTHERLAND, Ph.D.,

Research Associate in Physiology

AZUYATANIGUCHI. Ph.D.,

Research Associate in Physiology

OTAROTODA, M.D.,

Research Associate in Physiology

EINRICHWASNER, Ph.D.,

Research Auociate;'1 Physiolof!J

The Department of Physiology offers courses leading to the Ph.D.

egree. Courses described below which are numbered in the 300 series re offe,red primarily for that program but are open

to

medical students y speCIal arrangement.

01. PHYSIOLOGY.

(3U)

This course consists of lectures, conferences, nd laboratory work, designed to cover the essentials in physiology for rSt year medical students. It or its equivalent is also required of

all

aduate students majoring in pyhsiology. SPRING. [8]

Dr.

C.

Park.

1.,1.

TOPICSIN GENBRAL PHYSIOLOGY. First year. The course will start

Ith the basic cellular processes of accumulation, membrane transport,

SCHOOL OF MBDICINB .,

¹⁰⁾

bioelectric potentials, concraction, and secretion from the point of view of elementary applied physical chemistry. The discussion will extend to the operation of these processes in the function of erythrocytes, nerves, sensory receptors, muscles, glands, and excretory organs. When ap- plicable the mechanism of the hormonal concrol of these cells will be in- cluded. One hour per week. SPRING. Dr. Post.

52.2..LIlCTURESON RIlSBARCIIPROGRIlSSIN MOLECULARBIOLOGY. (35oa-nob) Second and Fourth years. A CGurse co-sponsored by the Departmenrs of Microbiology, Physiology, and Molecular Biology, in which members of these and other departments present their own research activities in relation to current problems in their field. First semester: biophysical aspects will be stressed, including the application of modern physicochemical techniques to studies of macromolecules and enzyme action. Second semes.

ter: physiological aspects will be stressed, including the molecular basis of the function of specialized tissues, and the mechanisms for metabolic control of gene action and mulri-enzyme systems. (Microbiology 52.2.) First and second semesters may be taken independendy. Two hours per week.

PALL

^&

SPRING. [2.-2.]

52.9. LIPID CHEMISTRYAND M41ABOLISM. (32.9). First, Second, and Four~

years. Lectures, discussions, and assigned readings in the chemistry, intestl.

nOliabsorption, transport, and metabolism of lipids. Emph ilsis will be place~

on the normal regulation of these processes and their alteration in patholog

^l'

COlIconditions. Prerequisite: a general course in biochemistry. (Physiology 52.9). One or two hours per week. SPRING. Dr. Coniglio and Dr. Mwg.

581. RIlSBARCHFULLOWSIIIPIN PHYSIOLOGY. Fourth year. Opportuni.ties will be available in the fields of membrane transport and intermediarY metabolism and in the hormonal concrol of these processes. Full time for twelve or eighteen weeks. Dr. C. Park.

582.. ADVANCBD PHYSIOLOGY. (32.3) Second and Fourth years. This COurse deals with special topics in physiology and consists of laboratory work and conferences. Prerequisite: 501 or equivalent. Hours and credit

by

arrangement. FALL

^&

SPRING. Dr. C. Park and Staff.

32.2.. PHYSIOLOGICALTECHNIQUESAND PRBPARATIONS. A course designed for advanced students. Hours and credit by arrangement. Dr. C. Park.

399. RESBARCH. Staff.

Preventive Medicine & Public Health

ROBERT W. QUINN, M.D., C.M., Profeuor of Preventille and Social Medici

nt

a'ld Chairman of the Departmmt of Preventille Medicine and Public Healfh RICHARDO. CANNON, M.D., Profeuor of Hospital Administration

LESLIE

A.

^FALK,

D.Phil., M.D., Clinical Professor of Pret'entive Medjcine an

Public Health

106 f

VANDBRBILT UNIVBRSITY

LVIN E. KELLER, M.D.,

Clitlical Profusor of Preventive Medicine and Public Health, Emeritus

EWISB. LBFKOWITZ, JR., M.D.,

Auociau Profusor of Preventive Medicine and Public fIealth

UGliNE

W.

FOWINKLE, M.D., M.P.H.,

Associate Clinical Profusor of Pre- I'mtive Medicine and Pltblic Health

UGIIALFREn DAVIES, Ph.D.,

Auistallf Profusor of Preventive Medicine

NNE SWIIllNIlY, M.A.,

A.r.ristant Profeuor of Medical SociallVork

. CARTER WILLIAMS, M.D., M.P.H.,

Auistant Profeuor of Preventive Medi- cine and Public llealth, Emeritus

OSEPIIM. BISTOWISJl, M.D., M.P.H.,

Auistant Clinical Profeuor of Preven- five Medicine and Public Health

UTI/M. HAGSTROM, M.D., M.P.H.,

Auistant Clinical Profusor of Preventive Medicine and PubliC Health

. DUDLI.Y NI LSON, M.D., M.P.H.&T.M.,

Auistant Clmical Profusor of Prmntite Medicme and Public I Jealth

. B.

TucKI R,

M.D., M.P.H.,

Auistant Clinical Profe.r.rorof Prevmtive Med-

icine and Public Health, E.merittu

ICIIAI L /.1'8KOII, Ph. D., Auutdfll CirnlCdi Pro/usor

0/

^{Pm'wt/ve Afedicim}

IIERI'SA

^ScOTT

CARTER, 1\I.S.S.\\".,

Instrue/or m Medical SociallVork

ROTIIY JI AN TURNER, 1\.1.0..,

Instrue/or in Pru'wtive Medicine

ILDERWALTON HUBBARD, M.D.,

Clinical Instrllctor in Prevmtive Medicine and PubliC Health

ON

O.

T. BALL,

Ruedrch Auociatr It1 Pnmuive Medicme and Public Health

ANUELNY! LOWRY, M.A.,

Resea,,/; A.r.rociatr /11 Preventive ~fedicim and

PubliC Ilealth

BIOSTATISTICS

HARLESF. FI nERSPIEL, Ph.D.,

Auociate Profusor of Biostatistics and Director of the Dtt'IS/Otl

VILLIAM

K. \T

AUGIIN, Ph

.0., Auistant Profusor of Biostatistics

OGERVANDER ZWAAG, Ph.D.,

AssistalJt Professor of Biostatistics

OMERA. SPRAGUE, M.P.H.,

Instructor in Biostatistics

ILEENEZELL, M.P.H.,

Clwlcal Instrue/or /11 BiostatistICS

AW

CIJIN Ho, Ph,D.,

Assistant Clinical Profusor of BIOstatistics

01. EPIDEMIOLOGY: GENERAL PRINCIPLliS AND l\.[nDlCAL STATISTICS. Before lasses begin in the fall, a memo will be circulated

to

the students mentioning hat a programmed text in medical statistics will be available for them

to

~Udy

at their convenience during the first four weeks of the semester. On

e first four Tuesday afternoons

(2.-4

p.m.) of the semester a series of

CtUtes on health services will be presented. At the end of the first four

ee~s. an examination will be given covering the material in medical

tatlstJcs utilizing the notation and covering the material of the pro-

rammed text. Those who get a passing grade on this examination will

e eXcused from the formal sessions. Those who do not pass will be re-