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PROOF Correction on Atom Indonesia Name of All Authors : Article Title : Uptake and Cytotoxicity Characterization of Radioiodine in MCF-7 and SKBR3 Breast Cancer Cell Lines E-mail :

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PROOF Correction on Atom Indonesia Name of All Authors :

Article Title : Uptake and Cytotoxicity Characterization of Radioiodine in MCF-7 and SKBR3 Breast Cancer Cell Lines

E-mail :

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Number Original Text Correction Note / Change

59-62 There are several molecular varieties of breast cancer cells, and in relation

to cell surface of NIS expression, they affect the radioiodine uptake [9].

In relation to cell surface of NIS expression with radioiodine uptake, there are varieties of cell surface NIS levels of breast cancer cells [9].

190 In this study In our study

( the data from our another study and do not publish yet)

197-198 Nakamoto et al. 197

reported, based on their study

Nakamoto et al. 197

reported, based on their in-vitro study

205 In this study In our study

( the data from our another study and do not publish yet)

309-312 This study shows that the amount of uptake and efflux of radioiodine in SKBR3 and MCF-7 cells does not correlate to the cytotoxic effect.

This study shows that the amount of uptake and efflux of radioiodine in HaCat cell does not relate to the cytotoxic effect.

312-318

SKBR3 cells showed a significantly higher uptake of radioiodine.

Furthermore, the radioiodine retention in SKBR3 cells over a one hour period was higher than that in MCF-7. The cytotoxic effect in MCF-7 cells was found to be higher than in SKBR3 as shown in Fig. 3

We need to add some explanation and make some changes that relate to cells, uptake and cytotoxicity as below :

Otherwise, SKBR3 showed a significantly higher uptake of radioiodine and reduced reproductive ability as shown in Fig 3. Interestingly, the MCF-7cell was found to be less uptake of radioiodine than in other cells.

However, the radioiodine treatment showed a significantly reduce reproductive ability of the cell as shown in Fig. 3

318-322 It can be assumed that the two types of breast cancer cells might have

It can be assumed that the two types of breast cancer cells might

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different proapoptosis gene expressions that can influence the sensitivity toward radioiodine exposure. Furher investigations are still needed to examine this finding.

have different proapoptosis genes expression that can influence the sensitivity toward radioiodine exposure. Further investigations are still needed to examine this finding

336-337

These factors can influence the cells' response toward radioiodine radiation [16].

These factors can influence the cells' response toward radioiodine exposure [16].

Please return to Atom Indonesia Editorial Office via e-mail: [email protected]

This original sheet should be returned to:

PPIKSN-BATAN, Secretariat of Atom Indonesia, Gedung 71, Lantai 1, Kawasan Puspiptek Serpong, Tangerang, Indonesia 15310

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