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TABLE 3: Clinical, immunological and virological profile of HIV-infected children at enrolment in hospital All Children
(N=55)*
Known HIV-Exposure Risk (N=46)*
Unknown HIV-Exposure Risk
(N=9)*
N N N
Age on admission (months) median(IQR) 5.7 (3-12.5) 4.5 (2.2-12.6) 9.3 (5.9-12.8)
Appropriately vaccinated for age∞ 46 29 (63) 39 24 (62) 7 5 (71)
Diagnosed during enrolment admission n(%) 25 (46) 17 (37) 8 (89)
Weight-for-Age Z-score median(IQR) -2.6 (-4.0 to
-1.9) -2.4 (-4.1 to -1.8) -3.4 (-4.2 to -2.3)
WHO Clinical Stage III + IV n(%) 44 (80) 36 (78) 8 (89)
Latest CD4% median(IQR) 49 25.1 42 27.7 7 24.7
WHO CD4% Immunodeficiency Staging n(%) 49 42 7
Advanced Immunodeficiency
(≤11 months: 25-29%; 12-35months: 20-24%) 9 (18) 7 (17) 2 (29)
Severe immunodeficiency
(≤11 months: <25%; 12-35 months: <20%) 17 (35) 15 (36) 2 (29)
Most common diagnoses n(%)
Pneumonia§ 25 (45)
Tuberculosis (TB)‡ 10 (18)
Diarrhoeal Disease 20 (36)
Severe Acute Malnutrition 22 (40)
Latest HIV viral load log median(IQR) 50 5.5 (4.1-6.3) 42 5.4 (3.9-6.2) 8 6.3 (5-6.7)
ART prior, in Care 14 3.9 (2.2-5.4) 14 3.9 (2.2-5.4)
ART prior, not in Care 5 5.9 (5.4-6.7) 5 5.9 (5.4-6.7)
Previously Diagnosed, no ART 9 6.2 (5.2-6.6) 8 6 (5.2-6.5) 1 6.7
Newly Diagnosed 22 5.5 (4.2-6.4) 15 5.4 (4.2-6) 7 6.2 (4.1-6.7)
Latest Viral load LDL n(%) 50 3 (6) 42 3 (7) 8
Duration of hospitalization (days) median(IQR) 17 (10-31) 15.5 (10-32.3) 23 (12-30.5)
* N as in column header unless otherwise specified; discrepancy in denominator in concordance with data available for specific parameter
∞ 7 of the 55 enrolled children still in the neonatal period and with no RtHB (Road-to-Health Booklet) issued were excluded (N=48,40,8)
§ 21 children had pneumonia only, 4 had pneumonia and pulmonary TB
‡ 2 children had pulmonary TB only, 4 had pneumonia and pulmonary TB, and 4 had other forms of TB LDL indicates lower than detectable limit (HIV viral load <50 copies/mL)
