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Supplemental Digital Content A.

Figure A1: Scatter plots and Pear son correlation coefficients of CVC55, CVC70, DIN and Time from CI to Study Variables and Outcome Evaluation (SVOE)

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Supplemental Digital Content B.

Supplemental Digital Content Table 1: Multivariate linear regression of possible electrode selection variables and type of electrode on outcome CVC65 in all participants with complete measurements (n=123). Participants with missing data were excluded from the model (n=6); all six were excluded due to inability to score scalar location due to poor quality CT-scan due to movement artifacts. The proportion of variance explained by the model in the Supplemental Digital Content Table 1 was 9%, the degrees of freedom were 9, 113 and 122, respectively for the model, the residual and the total.

Independent variable Coefficient 95% Conf. Interval p-value

1 Age at implantation -0,15 -0,48 0,19 0,39

2 Level of education (cat.)

< BSc Ref.

≥ BSc 0,87 -8,79 10,21 0,87

3 Years of Hearing loss 0,02 -0,24 0,29 0,88

4 Preoperative CVC – phonemescorea 0,19 -0,09 0,46 0,18

5 Preoperative PTA3 0,24 -0,10 0,58 0,16

6 Postoperative PTA3 -0,11 -0,10 0,58 0,60

7 Electrode type

Precurved Ref.

Straight -8,30 -16,80 1,97 0,11

8 Scalar trajectory (cat.)

All scala tympani Ref.

All scala vestibuli -3,75 -12,72 6,38 0,47

Translocation 0,98 -7,75 9,39 0,84

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Supplemental Digital Content Table 2: Multivariate linear regression of possible electrode selection variables and type of electrode on outcome DIN in all participants with complete measurements (n=117). Participants with missing data were excluded from the model (n=12); five were excluded due to inability to score scalar location due to poor quality CT-scan due to movement artifacts, three were excluded due to missing CVC50 outcome measurement, one was excluded for both these reasons, and three were excluded due to a DIN score above 15 SNR. The proportion of variance explained by the model in table 3 was 11%, the degrees of freedom were 9, 107 and 116, respectively for the model, the residual and the total.

Independent variable Coefficient 95% Conf. Interval p-value

1 Age at implantation 0,04 -0,13 0,22 0,64

2 Level of education (cat.)

< BSc Ref.

≥ BSc -2,43 -6,64 2,97 0,34

3 Years of Hearing loss 0,04 -0,10 0,17 0,59

4 Preoperative CVC – phonemescorea -0,01 -0,15 0,13 0,89

5 Preoperative PTA3 -0,05 -0,23 0,13 0,58

6 Postoperative PTA3 -0,01 -0,22 0,21 0,96

7 Electrode type

Precurved Ref.

Straight 5,39 -0,88 13,56 0,10

8 Scalar trajectory (cat.)

All scala tympani Ref.

All scala vestibuli 3,47 -2,29 10,94 0,26

Translocation 4,80 -0,52 11,45 0,08

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Supplemental Digital Content C.

Figure C1. Figure indicating distribution of residuals of multivariable linear regression model (Original Paper; Table 3). On the X-axis the fitted values of the multivariable model (or predicted values) are plotted, and on the Y-axis the residual values; indicating the difference between the predicted values and the found values in our study, are plotted.

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Table C1. Multivariate linear regression on dependent outcome CVC50 in participants with time from CI to SVOE ≥ 18 months (n=111).

Independent variable Coefficient 95% Conf. Interval p-value

1 Age at implantation -0,33 -0,72 0,06 0,09

2 Level of education (cat.)

< BSc Ref.

≥ BSc -2,67 -13,24 8,91 0,67

3 Years of Hearing loss -0,05 -0,38 0,28 0,77

4 Preoperative CVC – phonemescorea 0,15 -0,16 0,46 0,35

5 Preoperative PTA3 0,19 -0,22 0,59 0,37

6 Postoperative PTA3 -0,23 -0,70 0,25 0,35

7 Electrode type

Precurved Ref.

Straight -12,83 -21,90 -1,84 0,03

8 Scalar trajectory (cat.)

All scala tympani Ref.

All scala vestibuli -2,70 -13,13 8,75 0,66

Translocation -2,94 -1,50 7,28 0,58

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