Supplemental Digital Content A.
Figure A1: Scatter plots and Pear son correlation coefficients of CVC55, CVC70, DIN and Time from CI to Study Variables and Outcome Evaluation (SVOE)
Supplemental Digital Content B.
Supplemental Digital Content Table 1: Multivariate linear regression of possible electrode selection variables and type of electrode on outcome CVC65 in all participants with complete measurements (n=123). Participants with missing data were excluded from the model (n=6); all six were excluded due to inability to score scalar location due to poor quality CT-scan due to movement artifacts. The proportion of variance explained by the model in the Supplemental Digital Content Table 1 was 9%, the degrees of freedom were 9, 113 and 122, respectively for the model, the residual and the total.
Independent variable Coefficient 95% Conf. Interval p-value
1 Age at implantation -0,15 -0,48 0,19 0,39
2 Level of education (cat.)
< BSc Ref.
≥ BSc 0,87 -8,79 10,21 0,87
3 Years of Hearing loss 0,02 -0,24 0,29 0,88
4 Preoperative CVC – phonemescorea 0,19 -0,09 0,46 0,18
5 Preoperative PTA3 0,24 -0,10 0,58 0,16
6 Postoperative PTA3 -0,11 -0,10 0,58 0,60
7 Electrode type
Precurved Ref.
Straight -8,30 -16,80 1,97 0,11
8 Scalar trajectory (cat.)
All scala tympani Ref.
All scala vestibuli -3,75 -12,72 6,38 0,47
Translocation 0,98 -7,75 9,39 0,84
Supplemental Digital Content Table 2: Multivariate linear regression of possible electrode selection variables and type of electrode on outcome DIN in all participants with complete measurements (n=117). Participants with missing data were excluded from the model (n=12); five were excluded due to inability to score scalar location due to poor quality CT-scan due to movement artifacts, three were excluded due to missing CVC50 outcome measurement, one was excluded for both these reasons, and three were excluded due to a DIN score above 15 SNR. The proportion of variance explained by the model in table 3 was 11%, the degrees of freedom were 9, 107 and 116, respectively for the model, the residual and the total.
Independent variable Coefficient 95% Conf. Interval p-value
1 Age at implantation 0,04 -0,13 0,22 0,64
2 Level of education (cat.)
< BSc Ref.
≥ BSc -2,43 -6,64 2,97 0,34
3 Years of Hearing loss 0,04 -0,10 0,17 0,59
4 Preoperative CVC – phonemescorea -0,01 -0,15 0,13 0,89
5 Preoperative PTA3 -0,05 -0,23 0,13 0,58
6 Postoperative PTA3 -0,01 -0,22 0,21 0,96
7 Electrode type
Precurved Ref.
Straight 5,39 -0,88 13,56 0,10
8 Scalar trajectory (cat.)
All scala tympani Ref.
All scala vestibuli 3,47 -2,29 10,94 0,26
Translocation 4,80 -0,52 11,45 0,08
Supplemental Digital Content C.
Figure C1. Figure indicating distribution of residuals of multivariable linear regression model (Original Paper; Table 3). On the X-axis the fitted values of the multivariable model (or predicted values) are plotted, and on the Y-axis the residual values; indicating the difference between the predicted values and the found values in our study, are plotted.
Table C1. Multivariate linear regression on dependent outcome CVC50 in participants with time from CI to SVOE ≥ 18 months (n=111).
Independent variable Coefficient 95% Conf. Interval p-value
1 Age at implantation -0,33 -0,72 0,06 0,09
2 Level of education (cat.)
< BSc Ref.
≥ BSc -2,67 -13,24 8,91 0,67
3 Years of Hearing loss -0,05 -0,38 0,28 0,77
4 Preoperative CVC – phonemescorea 0,15 -0,16 0,46 0,35
5 Preoperative PTA3 0,19 -0,22 0,59 0,37
6 Postoperative PTA3 -0,23 -0,70 0,25 0,35
7 Electrode type
Precurved Ref.
Straight -12,83 -21,90 -1,84 0,03
8 Scalar trajectory (cat.)
All scala tympani Ref.
All scala vestibuli -2,70 -13,13 8,75 0,66
Translocation -2,94 -1,50 7,28 0,58