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(1)

a La Trobe໻ᄺ▇໻߽Ѯ㓈໮߽Ѯᴀ䖾ៜDŽ

b ᯚ຿݄म⠽佚ˈ▇໻߽Ѯᯚ຿݄Ꮧ䞠ᮃ⧁DŽ

c Menziesعᒋⷨおᄺ䰶▇໻߽Ѯ࣫乚ഄ䖒ᇨ᭛DŽ

d Ngalkanbuyि⫳Ёᖗ▇໻߽Ѯ࣫乚ഄGaliwin’kuDŽ

e ⱛᆊ䖒ᇨ᭛ए䰶ˈ▇໻߽Ѯ࣫乚ഄ䖒ᇨ᭛DŽ

f ᯚ຿݄໻ᄺˈ▇໻߽Ѯᯚ຿݄Ꮧ䞠ᮃ⧁DŽ

ᡩ〓᮹ᳳ˖2015ᑈ1᳜15᮹˗থ㸼᮹ᳳ˖2015ᑈ3᳜6᮹

1994-1996 ᑈ▇໻߽Ѯ࣫乚ഄأ䖰ೳ㨫⼒ऎܓ

ス੠៤Ҏ㙴䘧ᆘ⫳㰿⮙

Jennifer Shield

a

ˈ Kieran Aland

b

ˈ Thérèse Kearns

c

ˈ Glenda Gongdjalk

d

ˈ Deborah Holt

c

ˈ Bart Currie

ce

੠ Paul Prociv

f

䗮䆃԰㗙˖Jennifer Shield (䚂ㆅ: [email protected])DŽ

⫳㰿ᛳᶧӮᇍعᒋѻ⫳ϡ߽ᕅડDŽϹ䞡ⱘᆘ

⫳㰿ᛳᶧৃҹᓩথ䋿㸔ǃ㝍⋏੠㧹ݏϡ㡃ㄝ Ϲ䞡ⱘЈᑞ⮒⮙[1–5]DŽЁᑺ੠䕏ᑺᛳᶧৃҹ 䗴៤㧹ݏϡ㡃[6]ᑊৃҹ䗮䖛ࠞᔅ䅸ⶹ䖛⿟㗠ᕅડᬭ㚆 ᬜᵰ[7]DŽ↯佪䶁ൟ㒓㰿ᛳᶧϢ᥹⾡वҟ㢫ᇐ㟈ⱘܡ⭿

ॳᗻᏂ᳝݇[8]DŽ

䚼ߚ⾡㉏ⱘ㙴䘧ᆘ⫳㰿೼▇໻߽Ѯݰᴥ੠أ䖰

ೳ㨫⼒ऎⱘᛳᶧ⥛䴲ᐌ催DŽ䩽㰿˄Џ㽕ᰃकѠᣛ㙴 䩽 ষ 㒓 㰿 ˅ Џ 㽕 থ ⫳ ೼ फ 㒀22°ҹ ࣫ ᥹ 䖥 ⍋ ኌ 㒓 ⱘ

ഄऎ[9–12]DŽ䶁㰿˄↯佪䶁ൟ㒓㰿˅೼▇໻߽Ѯ㽓䚼[9]

↨䕗㔩㾕ˈԚ೼ᯚ຿݄[10]↨䕗ᐌ㾕ˈৠᯊгᄬ೼Ѣ࣫

䚼乚ഄ[10,13,14]DŽ㉾㉏೚㒓㰿↨䕗ᐌ㾕ˈߚᏗ೼ᭈϾ

࣫䚼ˈऴ▇໻߽Ѯ乚ೳⱘϝߚПѠ˄Jennifer Shieldˈ ᢝㅍԃ໻ᄺˈ᳾থ㸼ⱘ᭄᥂˅DŽⷂ㒺㰿˄ᖂᇣ㝰໇㒺 㰿˅੠कѠᣛ㙴䌒㄀㰿೼▇໻߽Ѯ㽓䚼ǃᯚ຿݄Ꮂ[1]

੠࣫䚼乚ഄⱘೳ㨫⼒ऎ䕗Ўᐌ㾕[9,10,13]DŽ䰓㉇Ꮘሲᆘ

⫳㰿೼ܼ▇໻߽Ѯഛ᳝থ⫳[1,15,16]DŽ೼㙴䘧ᆘ⫳㰿᠔

᳝㟈⮙⾡ሲЁˈ⒊㒘㒛䰓㉇Ꮘ⮙ᰃܼ⧗ᓩথ⅏ѵⱘ㄀

Ѡ໻ॳ಴ˈҙ⃵Ѣ⭳⮒[15]ˈकѠᣛ㙴؛㄀㰿ৃᓩ䍋᜶

ᗻ㝍⋏ǃ਌ᬊϡ㡃੠ԧ䞡ϟ䰡ˈ⫮㟇Ӯᇐ㟈ܓスথ㚆 䖳㓧੠䅸ⶹࡳ㛑䱰⹡[17]DŽ

䖛এˈᇍᆘ⫳㰿ᛳᶧᙷ⮙⥛ⱘ䆘Ԅᰃҹऩϔᆘ⫳

㰿Ў෎⸔䖯㸠DŽ✊㗠ˈⳂࠡⱘ䆕᥂ᰒ⼎ˈᔧϔϾҎᛳ ᶧњ2⾡ঞҹϞⱘᆘ⫳㰿ᯊˈ䙷Мᇍ㧹ݏ੠఼ᅬ⮙⧚ᄺ ⱘ䋳䴶ᕅડӮѻ⫳乱໪៪঴ࡴᬜᑨ[18]DŽ

▇໻߽Ѯ㙴䘧ᆘ⫳㰿䇗ᶹⱘⳌ݇᭛ゴথ㸼䕗ᇥDŽ ᴀ᭛ᇍ

1994

ᑈ㟇

1996

ᑈ▇໻߽Ѯأ䖰ೳ㨫⼒ऎⱘ㙴 䘧ᆘ⫳㰿ᙷ⮙ᚙމ䖯㸠ᦣ䗄DŽℸ㉏ⷨおⱘग़৆᭄᥂䴲 ᐌᇥ㾕ˈ಴ℸ݋᳝䕗催ӋؐDŽℸ໪ˈᴀ᭛ᓎゟњ᳝݇

㙴䘧ᆘ⫳㰿ᛳᶧⱘ෎㒓᭄᥂ˈ䗮䖛ᇚ݊Ϣᔧࠡᚙމ䖯 㸠↨䕗ˈৃҹᇍ偅㰿ㄪ⬹ᬜᵰ䖯㸠䆘ӋDŽ

(2)

♉ᬣᑺԄ䅵Ў93%ˈ⡍ᓖᑺԄ䅵Ў95%[21]DŽՓ⫼⢀ᓧ 佪㒓㰿ⱘᥦ⊘⠽ߚ⊠⠽԰Ўᡫॳᇍᓧ㲨㰿ሲ䖯㸠⌟

ᅮˈ݊♉ᬣᑺԄ䅵Ў91%ˈ⡍ᓖᑺԄ䅵Ў86%[22]DŽ 㒳䅵ߚᵤ

া᳝䞛⫼ᅮ䞣⬆䝯Э䝮⊩Ẕ⌟ߎ䰇ᗻᷛᴀˈᠡ߸ᅮЎ ᆘ⫳㰿ᛳᶧDŽখࡴ1⃵ঞҹϞ䇗ᶹⱘখϢ㗙ᠡ㹿䅵᳔ܹ

㒜䇗ᶹ㒧ᵰˈ㗠䇗ᶹᇍ䈵ҙ䅵ܹ݊㄀⃵Ẕ⌟㒧ᵰDŽᛳ ᶧ㗙ⱘ㰿ॉ䅵᭄ⱘ޴ԩᑇഛ᭄Փ⫼ᇍ᭄e԰Ўᑩ᭄䖯㸠

᭄᥂䕀ᤶᑊՓ⫼ডᇍ᭄ডㅫॉ᭄DŽᔧकѠᣛ㙴䩽ষ㒓 㰿੠↯佪䶁ᔶ㒓㰿ॉ᭄䗮䖛ᇍ᭄ࠏᑺ䖯㸠ߚ㒘ᯊˈ㒬 ࠊⱘ乥⥛ਜℷᗕߚᏗˈ㸼ᯢᔧᇍॉ᭄᭄᥂䖯㸠ᇍ᭄䕀

࣪ᯊˈ䗖⫼ѢℷᗕߚᏗⱘ㒳䅵ᮍ⊩ᰃ᳝ᬜⱘDŽᛳᶧᔎ ᑺḍ᥂Ϫ⬠ि⫳㒘㒛ߚ㉏䖯㸠ᔦ㉏[23]˄؛ᅮॉ᭄↿

छ㑺ㄝѢॉ᭄ܟ˅DŽ

ϸ Ͼ ⣀ ゟ ḋ ᴀ ↨ ՟ 䯈 ⱘ Ꮒ ᓖ ↨ 䕗 䞛 ⫼

Z

Ẕ 偠 ˈ

P

ؐ䞛⫼ঠջ៾ሒؐ˄ὖ⥛˅DŽབᵰᛳᶧ᭄៪䰈ᗻ᭄

໾ᇥˈ߭䞛⫼

Fisher

⹂ߛὖ⥛⊩DŽ⣀ゟḋᴀॉ᭄ⱘ㞾✊

ᇍ᭄䕀࣪ഛ᭄↨䕗䞛⫼ঠջWẔ偠DŽ乥⥛᭄᥂ߚᵤ䞛⫼

Yates’

वᮍẔ偠DŽ

P

ؐ

<0.05

㸼⼎Ꮒᓖ᳝ᰒ㨫ᗻᛣНDŽ ᠔᳝㒳䅵䅵ㅫഛ䞛⫼

VassarStats

㔥キᦤկⱘ೼㒓䅵ㅫ

఼䖯㸠

http://www.vassarstats.net/

ˈ⫼

Excel

㒬ࠊ೒

㸼DŽ Ӻ⧚ໄᯢ

ᴀⷨおᏆ㦋ᕫ▇໻߽Ѯ࣫乚ഄि⫳㕆੠Menziesعᒋⷨ

おᄺ䰶˄⊼ݠো˖EC00153˅Ҏ㉏ⷨおӺ⧚ྨਬӮⱘ ᥜᴗˈᡍޚোЎ94/19DŽ↣ϔԡ⦄എ⍖⠛ᆘ⫳㰿Ẕ⌟䰇 ᗻⱘ䇗ᶹᇍ䈵ഛӮ᥹ࠄਞⶹˈᑊ㽕∖ࠡᕔए⭫Ёᖗ䖯 㸠⊏⭫DŽ

㒧ᵰ

㙴䘧ᆘ⫳㰿⮙˖᠔᳝䇗ᶹⱘⱘ㓐ড়㉾֓䅵᭄

314

ৡ䇗ᶹ㗙Ёˈ㙴䘧ᆘ⫳㰿Ẕ⌟䰇ᗻ᠔ऴ↨՟Ў

89%

ˈϔ⾡ঞҹϞ㷩㰿ᛳᶧ䰇ᗻ᠔ऴ↨՟Ў

88%

DŽ

᳔ᐌ㾕ⱘᆘ⫳㰿⾡㉏Ў↯佪䶁ᔶ㒓㰿˄

86%

䰇ᗻ˅ˈ

݊⃵Ў䩽㰿˄

36%

˅ǃݙ䰓㉇Ꮘሲ>⒊㒘㒛ݙ䰓㉇Ꮘ˖

໻㙴ᴚ㦠ㄝ@˄

29%

˅ˈ㉾㉏೚㒓㰿˄

19%

˅ǃ㒺㰿

˄

16%

˅ǃकѠᣛ㙴䌒㄀㰿˄

10%

˅ǃ㳆㰿ǃ૛䶁

↯㰿ǃ㙴ݙⓈ㰿ǃҹঞ㢑ಞॳ㰿ሲ೼ᇥ᭄䇗ᶹ㗙ЁẔ ߎDŽ

314ৡখϢ㗙ᛳᶧ䩽㰿ⱘᔎᑺ˖䰈ᗻ˖ 64%˗

ᔅ䰇ᗻ˄1–1999ॉ᭄↿छ㉾֓˅˖35%˗Ёᑺ䰇

ᮍ⊩

ᇍ䈵੠⦄എ

ᴀⷨおѢ1994ᑈ7᳜㟇1996ᑈ10᳜೼▇໻߽Ѯϰ࣫䚼 䰓㒇ྚഄⱘϔϾأ䖰е䬛ᅲᮑDŽ䆹ഄऎ໻䚼ߚሙ⇥ሲ Ѣ▇໻߽Ѯೳ㨫䲡সᮣDŽ

㉾֓ᷛᴀⱘᬊ䲚

⬅ᆘ⫳㰿⮙ᡔᴃҎਬ੠عᒋᬭ㚆ϧϮҎਬᇍ↣᠋ᆊ ᒁ 䖯 㸠 䍄 䆓 䇗 ᶹ DŽ Փ ⫼ ᔧ ഄ 䇁 㿔 ᬊ 䲚 ᳝ ݇ 䩽 㰿 ᛳ ᶧǃӴ᪁੠䆞ᮁⱘֵᙃˈᑊᇍ㹿䇗ᶹ㗙䞛䲚㉾֓ᷛ

ᴀDŽ↣ৡফ䇗ᶹ㗙ഛߚথϔϾᷛ䆄དⱘᏺ᳝ᨁᠷᓣ Ⲫᄤⱘ䭓ᮍᔶล᭭ᆍ఼੠ϔϾ⠯Ⲃ㒌㹟DŽ⃵᮹ᮽ᰼

ᬊ䲚ᆍ఼DŽᷛᴀ೼ҹϟϾᯊ䯈↉䞛䲚˖1994ᑈ7᳜

˄

7

1᮹ ࠄ 18᮹ ˅ ˈ 1994ᑈ 10᳜ ˄ 9᳜ 30

᮹ 㟇

10᳜19᮹˅ˈ 1994ᑈ12᳜˄12᳜8᮹㟇19᮹˅ˈ 1995ᑈ5᳜˄5᳜5᮹㟇22᮹˅ˈ1995ᑈ8᳜˄8᳜4᮹

㟇19᮹˅ˈ1995ᑈ12᳜˄11᳜20᮹㟇12᳜19᮹˅ˈ

1996ᑈ 10᳜˄⹂ߛ᮹ᳳ᳾䆄ᔩ˅DŽ݊Ёˈ11᳜੠

12᳜໘Ѣ䲼ᄷˈ݊ԭḋᴀᬊ䲚ᯊ䯈ഛ໘ѢᯅᄷDŽ

㉾֓ᷛᴀẔ⌟

೼⦄എᅲ偠ᅸˈሑᖿᇍࡴܹⲤ∈⑓໘⧚ⱘ㉾֓ᷛᴀ䖯 㸠ᰒᖂ䬰Ẕˈ

0.91

↿छⱘㄝӑ㉾֓ࡴܹ

5–10

↿छ

4%

ⱘ⬆䝯ˈПৢ䞛⫼ᅮ䞣⬆䝯Э䝮䅵᭄⊩䖯㸠Ẕ偠DŽᇍ 䩽㰿੠↯佪䶁ᔶ㒓㰿㰿ॉ䖯㸠䅵᭄ҹঞᇍ㉾㉏೚㒓 㰿ǃकѠᣛ㙴䌒㄀㰿ǃ䰓㉇Ꮘ㰿ሲㄝ䖯㸠䆄ᔩDŽ↣↿

छ㉾֓Ёⱘ㰿ॉ᭄䗮䖛݀ᓣ䅵ㅫ˄㉾֓ ⍂⎆>㉾֓

ḋᴀⱘᆍ⿃ḋᴀⱘԧ⿃@˅DŽ๲Ⅺ಴ᄤⱘ໻ᇣ೼

10

42

П䯈DŽՓ⫼ᮃᠬᇨ᷵ℷ಴ᄤᇍ䅵᭄䖯㸠䇗ᭈˈҹֱ

ᣕϡৠ㉾֓ᷛᴀⱘϔ㟈ᗻ[19]DŽ 䩽㰿⾡㉏ⱘ⹂ᅮ

ᇚ㳁⷇෍ݏⱘ10ӑ㉾֓ḋᴀҹঞ໻䞣ⱘ㰿ॉⳈ᥹⍖⠛

ҹ⹂ᅮ෎Ѣϱ⢊㲈ᔶᗕϞⱘ䩽㰿⾡㉏[20]DŽ

䗮 䖛 ሌ Ẕ ⌕ ⌾ ⢫ ⱘ ⍜ ࣪ ㋏ 㒳 ᬊ 䲚 ៤ ᑈ 䩽 㰿 DŽ ᇍ12ӑ៤㰿ḋᴀ䖯㸠䆺㒚Ẕ⌟ҹ⹂ᅮ݋ԧ⾡㉏DŽ 㸔⏙ᄺẔ⌟˄⡍ᓖᗻ㸔⏙ܡ⭿⧗㲟ⱑ

G

˄

IgG

˅ Ẕ⌟˅

ᢑপ39ৡ៤Ҏ੠ܓスⱘ䴭㛝㸔䖯㸠ᐌ㾘Ẕ⌟ᑊՓ⫼䝊 㘨ܡ⭿਌䰘⌟ᅮ⊩Ẕ⌟㒓㰿੠㲨㰿ⱘIgG∈ᑇDŽՓ⫼

S.ratti L3԰Ўᡫॳᇍ㉏೚㒓㰿ሲ䖯㸠⌟ᅮˈ䆹Ẕ⌟ⱘ

(3)

ᣛ㙴䌒㄀㰿੠⒊㒘㒛ݙ䰓㉇Ꮘᛳᶧ䰇ᗻ⥛П䯈ⱘᏂᓖ ᮴ᰒ㨫ᗻᛣНDŽ

⃵䇗ᶹЁ䩽㰿䰇ᗻᷛᴀॉ᭄޴ԩᑇഛ᭄᮴ᰒ㨫 ᗻᏂᓖ˄㸼

1

˅DŽ

1995

2

᳜䇗ᶹⱘ↯佪䶁ᔶ㒓㰿ॉ᭄

޴ԩᑇഛ᭄ᰒ㨫催Ѣ݊Ҫ䇗ᶹⱘ∈ᑇ˄

P < 0.001

˅

˄㸼

1

˅DŽ䖭Ͼ㒧ᵰৃ㛑Ϣ䇗ᶹܓス˄

0–14

ቕ˅ⱘ㰿

ॉ䅵᭄催᳝݇DŽ ᑈ啘੠ᗻ߿↨䕗

219ৡফ䇗ᶹ㗙ⱘᑈ啘Ёԡ᭄Ў11ቕ˄ಯԡߚ᭄䯈䎱

Ў6–29ቕ˅˄㸼1˅˗129ৡܓスᑈ啘೼0–14ቕП䯈

˄໻㑺ऴܓスҎষ᭄ⱘ37%˅ˈ91ৡফ䇗ᶹ៤Ҏᑈ啘

೼15ቕঞҹϞ˄໻㑺ऴ៤ҎҎষ᭄ⱘ12%˅DŽᄺ啘ܓ ス˄5–14ቕ˅ⱘӏϔᆘ⫳㰿ᛳᶧ⥛ഛ催Ѣᄺ啘ࠡܓス

˄0–4ቕ˅ˈབ䩽㰿ǃ↯佪䶁ᔶ㒓㰿੠䰓㉇Ꮘሲ㉏ᆘ

⫳㰿DŽϢᄺ啘ܓスⳌ↨ˈ៤Ҏ˄ı15ቕ˅ⱘ㉾㉏೚㒓 㰿ǃ㒺㰿ǃकѠᣛ㙴䌒㄀㰿ǃ䰓㉇Ꮘሲ㉏ᆘ⫳㰿ᛳᶧ

⥛䕗Ԣ˄㸼1˅DŽ䩽㰿ǃ↯佪䶁ᔶ㒓㰿ǃ㒺㰿੠䰓㉇Ꮘ ሲ㉏ᆘ⫳㰿ᄬ೼Ѣ0–1ቕܓスԧݙDŽ᠔᳝6⾡ᆘ⫳㰿ഛ ᄬ೼Ѣ2–4ቕܓスԧݙ˄೒1˅DŽ

ᗻ˄

2000–3999

ॉ᭄↿छ㉾֓˅˖

1%

DŽ

T.

䶁㰿˖

䰈 ᗻ ˖

16%

ˈ ᔅ 䰇 ᗻ ˄

1–999

ॉ ᭄ ↿ छ ˅ ˗ Ё ᑺ 䰇 ᗻ ˄

1000–9999

ॉ ᭄ ↿ छ ˅ ˖

30%

ˈ ᔎ 䰇 ᗻ

˄ı

10 000

ॉ᭄↿छ˅˖

4%

DŽ

39ৡখϢ㗙ⱘ㸔⏙ᄺ䆞ᮁᰒ⼎28%Ў㉾㉏೚㒓㰿

ᛳᶧ䰇ᗻˈ18%Ўৃ⭥䰇ᗻˈ21%Ў⭥⢀㲨㰿ᛳᶧ䰇 ᗻˈ5%Ўৃ⭥䰇ᗻDŽᑈ啘Ёԡ᭄Ў32ቕ˄ಯߚԡ᭄䯈 䎱Ў24–41˅DŽ

7

⃵䇗ᶹ↨䕗

55

˄

18%

˅ৡখϢ㗙খࡴ䇗ᶹ⃵᭄䍙䖛⃵DŽ䩽㰿䰇 ᗻ⥛Ϣ㉾㉏೚㒓㰿䰇ᗻ⥛П䯈ⱘᏂᓖ݋᳝ᰒ㨫ᗻᛣН

˄㸼

1

˅DŽ䩽㰿䰇ᗻ⥛೼

1994

10

᳜䲼ᄷࠡ䕗催ˈৃ

㛑⬅Ѣ䰓㣃䖒૥偅㰿⊏⭫乍Ⳃⱘᅲᮑˈᬙ

1995

8

᳜ 䰇ᗻ⥛䕗Ԣˈ

1995

12

᳜䲼ᄷᯊ䕗催DŽ

1994

10

᳜ Ϣ

1 9 9 6

1 0

᳜ Ⳍ ↨ ˈ 䩽 㰿 䰇 ᗻ ⥛ ᳝ ᯢ ᰒ 䰡 Ԣ

˄

P < 0 . 0 0 2

˗㸼

1

˅ DŽ ㉾ ㉏ ೚ 㒓 㰿 䰇 ᗻ ⥛ Ѣ

1995

5

᳜ᯊ䕗催ˈৃ㛑䱣ⴔ䰓㣃䖒૥偅㰿⊏⭫乍Ⳃ ⱘᅲᮑˈ

1995

8

᳜ᯊ䕗Ԣˈ

1995

12

᳜䲼ᄷᯊ䕗 催ˈ

1996

10

᳜䕗Ԣ˄㸼

1

˅DŽ↯佪䶁ᔶ㒓㰿ǃकѠ

㸼1. 1994ᑈ7᳜㟇1996ᑈ10᳜▇໻߽Ѯ࣫乚ഄ㙴䘧ᆘ⫳㰿䇗ᶹҎ㕸䰇ᗻ⮙՟᭄ঞ↨՟ˈn = 383

䇗ᶹ᮹ᳳ ফẔ Ҏ᭄

ӏϔᆘ⫳㰿 䩽㰿 ↯佪䶁ᔶ㒓㰿 ㉾㉏೚㒓㰿 㒺㰿 कѠᣛ㙴䌒㄀㰿 ݙ䰓㉇Ꮘሲ 䰇ᗻ᭄

(%)

䰇ᗻ᭄

(%)

޴ԩᑇഛ᭄

ॉ᭄↿छ [Exp (CI)]

䰇ᗻ᭄

(%)

޴ԩᑇഛ᭄

ॉ᭄↿छ [Exp (CI)]

䰇ᗻ᭄

(%)

䰇ᗻ᭄

(%)

䰇ᗻ᭄

(%)

䰇ᗻ᭄

(%)

1994ᑈ7᳜ 62 57 (92) 19 (31) 200 53 (86) 820 13 (21) 15 (24) 10 (16) 18 (29)

[120–350] [520–1300]

1994ᑈ10᳜ 76 73 (94) 43 (57)* 180 68 (89) 560 13 (16) 13 (16) 9 (11) 22 (27)

[120–250] [390–800]

199412 37 31 (84) 17 (46) 110 29 (78) 400 4 (11) 3 (8) 3 (8) 11 (30)

[61–190] [260–620]

1995ᑈ5᳜ 48 44 (92) 16 (33) 120 40 (83) 800 17 (35)* 7 (15) 0 (0) 10 (21)

[73–200] [460–1400]

19956 ऩࠖ䞣䰓㣃䖒૥偅㰿⊏⭫ᮍḜ᳓ҷ౏৽௻୊੠⬆㣃੾૥⊏⭫ᮍḜ

19958 63 57 (90) 7 (11)* 130 53 (84) 520 6 (19)* 12 (19) 4 (6) 23 (37)

[42–420] [360–740]

199512 44 41 (93) 15 (34)* 140 38 (86) 2200* 13 (30)* 12 (27) 5 (11) 17 (27)

[79–250] [1400–3300]

1996ᑈ10᳜ 53 46 (87) 13 (25) 100 44 (83) 380 4 (8)* 7 (13) 5 (9) 21 (40)

[53–180] [230–640]

ᘏ䅵c 383 349 (91) 130 (34) 100 325 (85) 650 70 (18) 69 (18) 36 (9) 122 (32)

[110–190] [550–780]

Exp (CI)㕂ֵऎ䯈˗޴ԩഛ᭄ˈফᛳᶧⱘ޴ԩᑇഛ᭄DŽ

Ϣҹࠡⱘ䇗ᶹⳌ↨ᰒ㨫ᏂᓖDŽ

Ϣϔᑈࠡ䇗ᶹⳌ↨݋᳝ᰒ㨫ᏂᓖDŽ

Ϣ᠔᳝݊ᅗ䇗ᶹⱘ޴ԩഛ᭄Ⳍ↨᳝ᰒ㨫ᏂᓖDŽ

c ᶤѯ䇗ᶹ㗙খϢ໮⃵䇗ᶹDŽ

(4)

ऩࠖ䞣

20

↿ܟगܟˈ៪⬆㣃੾૥↣᮹

100

↿ܟˈϔ ᮹ϸ⃵ˈ䖲㓁Փ⫼

3

໽DŽ㞾

1995

5

᳜䍋ˈ䰓㣃䖒૥

˄ ԧ 䞡 ೼

8–10

݀ ᭸ П 䯈 ⱘ ܓ ス ऩ ࠖ 䞣

200

↿ ܟ ˈ 䍙 䖛

1 0

݀ ᭸ ⱘ ܓ ス ऩ ࠖ 䞣 Ў

4 0 0

↿ ܟ ˅ ᓔ ྟ ԰ Ў ↣ ᑈ ܓ ス ԧ Ẕ ⱘ ᐌ ⫼ 偅 㰿 㥃 ˗ ៤ Ҏ ੠ ܓ ス ⭥ Ԑ ⹂ 䆞 㙴 䘧 ᆘ ⫳ 㰿 ⮙ ᛳ ᶧ 㗙 ˈ ᷛ ޚ ⊏ ⭫ ⿟ ᑣ ᰃ

↣ ᮹

400

↿ ܟ 䰓 㣃 䖒 ૥ ˈ 䖲 㓁 Փ ⫼

3

໽ DŽ ㉾ ֓ Ẕ

⌟ ߎ ⱘ ᆘ ⫳ 㰿 ⾡ ㉏ ೼ ৠ ϔ ഄ ऎ ৠ ᯊ ᓔ ሩ ⱘ ϸ Ͼ ᇣ ൟ ⷨ お Ё Ⳍ Ԑ[10,13]ˈ Ԛ ᰃ ᴀ ⷨ お ᕫ ߎ ⱘ 䰇 ᗻ

⥛ ᳈ 催 DŽ 䖭 ৃ 㛑 ᰃ ಴ Ў ⬆ 䝯 Э 䝮 ᅮ 䞣 ⊩ ⱘ ♉ ᬣ ᑺ

᳈ 催 ᠔ 㟈 DŽ ሑ ㅵ 䖭 ⾡ ᮍ ⊩ ⱘ ♉ ᬣ ᑺ ໻ ໻ 催 Ѣ Ⳉ ᥹

⍖⠛⊩ˈԚᰃ䖭г᳝ৃ㛑Ϣ㉾֓Ẕᶹⱘ᭄䞣Ⳍᇍ໻᳝

݇ˈᑊϨ䆹ᮍ⊩ᕜৃ㛑ԢԄњᅲ䰙ᙷ⮙⥛˗՟བˈᇣ

㒘˄

n = 39

˅㸔⏙ᄺẔ⌟䰇ᗻⱘ㉾㉏೚㒓㰿ᙷ⮙⥛Ў

ᄺ 啘 ܓ ス ⱘ ↯ 佪 䶁 ᔶ 㒓 㰿 ॉ ᭄ ⱘ ޴ ԩ ᑇ ഛ ᭄

˄

1200

ॉ↿छ˅ᰒ㨫催Ѣᄺ啘ࠡܓス˄

400

ॉ↿

छ˅੠៤Ҏ˄

410

ॉ↿छ˅˄

P<0.001

˅DŽ৘ᑈ啘↉ ᵘ䩽㰿ॉ᭄ⱘ޴ԩᑇഛ᭄П䯈ⱘᏂᓖ᮴ᰒ㨫ᗻDŽ

᳝ᯢ⹂ᗻ߿䆄ᔩⱘ䇗ᶹ㗙Ёˈ⬋ᗻ

100ৡˈཇ

ᗻ115ৡDŽ⬋ᗻফ䇗ᶹ㗙Ё䩽㰿ᛳᶧ⥛˄

47%ᇍ↨

30%ˈ P = 0.012˅ǃ↯佪䶁ᔶ㒓㰿ᛳᶧ⥛˄92%ᇍ

↨79%ˈ

P = 0.0082˅੠कѠᣛ㙴䌒㄀㰿17%ᇍ↨

6% P = 0.011ᛳᶧ⥛ᰒ㨫催ѢཇᗻDŽ

໮䞡ᆘ⫳㰿ᛳᶧ

314ৡ 㹿 䇗 ᶹ 㗙 Ё ˈ 152Ҏ ˄ 48%˅ ᛳ ᶧ ໮ ⾡ ᆘ ⫳

㰿ˈ109Ҏ˄35%˅ϡҙᛳᶧϔ⾡ঞҹϞⱘᆘ⫳㰿㗠 Ϩᛳᶧ໮⾡ॳ㰿˄㸼2˅DŽᆘ⫳㰿Ϣॳ㰿ᛳᶧП䯈݋᳝

㒳䅵ᄺ݇㘨˄P = 0.0039˅DŽ 䩽㰿⾡㉏

Ң㳁⷇㉾֓෍ݏ㦋ᕫⱘᛳᶧᗻᑐ㰿ഛ⹂䅸Ў䩽ষ㒓㰿 ሲˈ᳔᳝ৃ㛑ЎकѠᣛ㙴䩽㰿DŽҢ⢫䑿Ϟᬊ䲚ࠄⱘ៤ 㰿⹂䅸Ў⢀໡ᄨ㒺㰿DŽ

䅼䆎

ҹϞ㒧ᵰ㸼ᯢˈሑㅵ೼ⷨおᓔྟࠡᏆ㒣ᓔሩњܓス 偅㰿䅵ߦˈԚ1994ᑈ㟇

1996ᑈ䇗ᶹ⼒ऎЁҎ㕸ᛳ

ᶧϔ⾡៪໮⾡㙴䘧ᆘ⫳㰿⮙ⱘᙷ⮙⥛ҡ✊䴲ᐌ催DŽ

1994ᑈˈ㙴䘧ᆘ⫳㰿⮙ⱘᷛޚ⊏⭫ᮍḜЎ౏৽௻୊

㸼2. 1994ᑈ᳜ࠄ1996ᑈ10᳜▇໻߽Ѯ࣫乚ഄ㷩㰿 ড়ᑊॳ⫳䴲ॳ⫳ࡼ⠽ᛳᶧ᠔ऴ↨՟˄n = 314˅*

*᳝ᆘ⫳㰿ᛳᶧॳ㰿ᛳᶧ˄P = 0.0039˅ⱘ㒳䅵Ϟᰒ㨫݇㘨 0

10 20 30 40 50

0 1 2 3 4

ᛳᶧ↨՟ᛳᶧ↨՟

㷩㰿⾡㉏ 㷩㰿⾡㉏

ҙ⳱⯻Ყ଀ ⳱⯻๺ේ↢ࡼ‛ว䅵Ყ଀

0 20 40 60 80 100

0–1 2–4 5–14 15ቕ෸એ਄

䰇ᗻ⥛䰇ᗻ⥛%

ᑈ啘㒘˄ቕ˅

ᑈ啘㒘˄ቕ˅

A. duodenale T. trichiura S. stercoralis R. nana G. duodenalis Entamoeba spp

1. 1994

7

᳜㟇

1996

10

᳜▇໻߽Ѯ࣫䚼乚ഄ৘ᑈ啘㒘䇗ᶹ㗙Ёϡৠ㙴䘧ᆘ⫳㰿䰇ᗻ⥛

* ᑈ啘㒘ᦤկ219খϢ㗙˄70 ˁ˅ˈ 0–4ቕᑈ啘㒘ߚЎ0–12–4DŽ

कѠᣛ㙴䩽ষ㒓㰿

↯佪䶁ᔶ㒓㰿

㉾㉏೚㒓㰿 㒺㰿 कѠᣛ㙴䌒㄀㰿 ݙ䰓㉇Ꮘሲ

(5)

[33]ˈ䖭гৃ㛑ᰃ⬅Ѣೳ㨫Ҏ㕸Ёᅲᮑњ䰓㣃䖒૥偅 㰿乍ⳂDŽ

⢀㲨㰿ᐌᆘ⫳Ѣ⢫ˈѻॉ៤㰿Џ㽕ᆘ⫳Ѣ⢫ᑐ

጑DŽ៥Ӏᇍ

21%

ⱘফẔҎ㕸䖯㸠⢀㲨㰿⡍ᓖᗻ

LgG

ᡫ ԧẔ⌟ˈ㒧ᵰᰒ⼎Ҏ㉏ᲈ䴆ᛳᶧ⥛䕗催˄ৃ㛑⬅Ѣ㰿

ॉᨘܹ᠔㟈˅DŽⳌ↨Пϟˈ

20

Ϫ㑾

90

ᑈҷⱘ䇗ᶹᰒ

⼎ˈ೼䕗䖰ⱘ▇໻߽Ѯϰ࣫䚼䰓㒇ྚഄऎⱘ঺ϔೳ㨫 Ҏ㕸Ё㸔⏙䰇ᗻ⥛Ў

43%

[10]ˈ࣫乚ഄⱘ঺ϔᮣ㕸㸔⏙

䰇ᗻ⥛Ў

11.1%

ˈ㗠▇໻߽Ѯ᱂䗮Ҏ㕸㸔⏙䰇ᗻ⥛Ў

5.7%

[34]DŽೳ㨫ҎষЁⱘ↯佪䶁ᔶ㒓㰿ᛳᶧⱘЈᑞϹ 䞡ᗻᇮϡ⏙ἮDŽᑐ㰿ৃᓩ䍋㙱㛣⮒⮙˄ݙ㛣ᑐ㰿⿏㸠

⮛˅៪ⴐ䚼⮙ব˄ⴐᑐ㰿⿏㸠⮛˅[19]DŽݙ㛣ᑐ㰿⿏㸠

⮛᳒㒣೼࣫䚼ഄऎ䴲ೳ㨫Ҏ㕸Ёথ⦄ˈԚᰃ䖥޴ᑈᑊ

≵᳝থ⦄ೳ㨫ሙ⇥⹂䆞⮙՟

Bart Currie

ˈ䖒ᇨ᭛ⱛᆊ ए䰶᳾থ㸼᭄᥂DŽ

㉾㉏೚㒓㰿ᛳᶧ䰇ᗻ⥛ⱘব࣪ᕜ䲒㾷䞞DŽ᳝᳒䆄 ᔩᰒ⼎ℸ⠽⾡ৃ䯈ℛᥦߎᑐ㰿[35]ˈৃ㛑⫼Ѣ㾷䞞ᛳᶧ

⥛ব࣪DŽ঺ϔ⾡ৃ㛑ᗻᰃ౏৽௻୊ǃ⬆㣃੾૥៪䰓㣃 䖒૥ㄝ㥃⠽ϡ㛑ḍ䰸ᛳᶧˈҙ㛑᱖ᯊᗻⱘޣᇥᑐ㰿ᥦ ߎDŽⳂࠡˈՓ⫼Ӟ㓈㦠㋴ৃҹ໻໻ᦤ催⊏⭫ࡳᬜ[25]DŽ ᇍܼ⼒ऎՓ⫼Ӟ㓈㦠㋴⊏⭫㉾㉏೚㒓㰿ᛳᶧⱘ᳝ᬜᗻ 䆘Ԅℷ೼ᅲᮑ[26]DŽ

1996ᑈ10᳜ⱘ䇗ᶹ㒧ᵰᰒ⼎ˈ䰓㣃䖒૥⊏⭫乍

Ⳃℷ೼䰡Ԣ䩽㰿ⱘᙷ⮙⥛ˈॳ಴ᰃ೼ϔᑈЁकѠᣛ㙴 䩽㰿ӥ⳴ᑐ㰿៤❳ᳳ䯈䇗ᶹ㗙ⱘ䩽㰿ᛳᶧ⥛ᰒ㨫䰡 ԢDŽ䖭ϔ㒧ᵰгϢ᥹ফ䰓㣃䖒૥⊏⭫㗙ৃҹ⍜䰸ӥ⳴

ᑐ㰿ᰃϔ㟈ⱘDŽ1995ᑈ8᳜䩽㰿䰇ᗻ⥛ߎ⦄䰡ԢϢ䰓 㣃䖒૥⊏⭫乍Ⳃᓔྟᅲᮑ᳝݇DŽ䖥ᳳᎹ԰ᰒ⼎ˈकѠ ᣛ㙴䩽㰿Ꮖᕫࠄᕜདⱘ᥻ࠊ[36,37]ˈԚᰃܓスᛳᶧ↯佪 䶁ᔶ㒓㰿੠㒺㰿ⱘ↨՟ҡ✊ᕜ催[37]DŽ᳔䖥ⱘϔ㆛෎Ѣ ᅲ偠ᅸ᭄᥂ⱘ㓐䗄ᰒ⼎ˈ࣫䚼乚ഄ↯佪䶁ᔶ㒓㰿ⱘẔ ߎ⥛೼䖛এᑈਜᯢᰒϟ䰡䍟࢓[14]DŽऩࠖ䞣䰓㣃䖒૥

⍜䰸ܓス↯佪䶁ᔶ㒓㰿ⱘ᳝ᬜᗻԢѢ៤Ҏ[38]ˈৠᯊг ԢѢ⍜䰸㒺㰿᳝ᬜᗻ[39]DŽ៥Ӏⱘ㒧ᵰϢℸᰃϔ㟈ⱘDŽ 䖲㓁3໽↣໽Փ⫼䰓㣃䖒૥ৃҹᦤ催⍜䰸↯佪䶁ᔶ㒓 㰿ǃ㒺㰿੠कѠᣛ㙴䌒㄀㰿ㄝⱘ᳝ᬜᗻ[38,39]DŽ

ⷨおЁ㾖⌟ࠄⱘ䰓㉇Ꮘ㦠ሲᆘ⫳㰿ᛳᶧϡ㛑⹂

ᅮᰃ৺݋᳝݀݅ि⫳ᛣНDŽ㽕⹂ᅮ㹿䇗ᶹ㗙Ёᛳᶧ⒊ 㒘㒛䰓㉇Ꮘ੠

moshkovski

䰓㉇Ꮘ⮙ॳԧⱘᛳᶧ⿟ᑺ䳔 㽕䖯㸠㉾֓ߚᄤẔ⌟ˈ㱑✊⦄೼ৃҹᅲᮑ䖭乍Ẕ⌟ᡔ ᴃˈԚ೼ᔧᯊᰃ᮴⊩䖯㸠ⱘDŽ

঺ϔϾৃ㛑ᇐ㟈催ᙷ⮙⥛ⱘ಴㋴ᰃ↣᠋䇗ᶹᆊᒁ Ё᳝໻䞣Ҏਬሙԣ೼ϔ䍋[40]ˈ䲒ҹֱ䆕亳⠽ޚ໛੠⏙

⋫䖛⿟ⱘि⫳ˈ⍜↦䆒ᮑгϡᅠ୘[41]DŽ᳔䖥ˈᔧഄℷ

28%ˈ㗠໻㒘˄n = 314˅䗮䖛⬆䝯Э䝮⊩Ẕ⌟ᰒ⼎ᙷ

⮙⥛߭Ў19%DŽ঺ϔϾⳌԐⷨおᰒ⼎ˈՓ⫼Э䝌Э䝃 ҷ᳓Э䝮ৢ♉ᬣᑺᰒ㨫ԢѢՓ⫼⨐㛖ᑇᵓ෍ݏ⊩[24]DŽ 㸔⏙ᄺẔ⌟䰇ᗻ䆩偠㸼ᯢབᵰ㉾㉏೚㒓㰿偅䰸ˈ䗮䖛

3–6Ͼ᳜ⱘ᳝ᬜ⊏⭫ᡫԧৃҹ䕀䰈

[25,26]DŽ

㱑✊Ң㳁⷇෍ݏЁ㦋ᕫⱘᑐ㰿Ў䩽㰿⾡ሲˈϨ

᳔໻ৃ㛑ЎकѠᣛ㙴䩽㰿ˈԚᰃ㕢⌆䩽㰿Ѻϡ㛑ᥦ 䰸DŽकѠᣛ㙴䩽㰿гৃ㛑ᄬ೼ˈ಴Ў▇໻߽Ѯ⢫ԧݙ ᄬ೼䆹ᆘ⫳㰿[27]ˈҎԧݙѺẔ⌟ߎ䆹ᆘ⫳㰿[28]DŽ៥ Ӏ㾖ᆳࠄ䩽㰿ᛳᶧ䰇ᗻ⥛䱣ⴔᄷ㡖㗠ব࣪ˈ䖭ϔ䆕᥂

㸼ᯢकѠᣛ㙴䩽㰿ᕜৃ㛑Ў䩽㰿ᛳᶧⱘЏ㽕⾡ሲDŽ䖭

⾡ᄷ㡖ᗻব࣪ᕜৃ㛑ᰃ಴Ўˈᑐ㰿೼ᯅᄷ⌏ࡼ࡯Ԣˈ 㗠೼䲼ᄷӴ᪁Ⳍᇍ๲ᔎ[29]DŽकѠᣛ㙴䩽㰿៤㰿ⱘᇓ

ੑ໻ὖЎϾ᳜DŽᑐ㰿೼䲼ᄷৢᳳ䖯ܹ䑿ԧ㳄ӣˈѢ ᯅᄷৢᳳ៤❳DŽ౏৽௻୊ৃҹᴔ⅏कѠᣛ㙴䩽㰿៤ 㰿ˈԚ᮴⊩⍜♁ӥ⳴ᳳⱘᑐ㰿[29]DŽ䰇ᗻ⥛ⱘ催ዄԡѢ

1994

10

᳜ˈ݊⃵ЎᯅᄷৢᳳDŽ䩽㰿೼䲼ᄷӴ᪁࡯๲

ᔎৃ㛑ᰃ䗴៤

1994

ᑈ੠

1995

ᑈⱘ

12

᳜ӑकѠᣛ㙴䩽 㰿ᛳᶧ䰇ᗻ⥛催ⱘॳ಴DŽ

ᴀⷨおথ⦄ϸ⾡៪ҹϞ໮⾡㙴䘧ᆘ⫳㰿ᛳᶧⱘᙷ

⮙⥛催ˈؐᕫ݇⊼DŽ⬅Ѣϡৠⱘᆘ⫳㰿⠽⾡ৃᓩথϡ ৠ⮙⧚ᄺᬍবˈҢ㗠ᇐ㟈݋᳝໮䞡ᆘ⫳㰿ᛳᶧⱘϾԧ ⱘথ⮙⥛๲催[18]DŽ⬋ᗻ䕗ཇᗻ᳈ᯧᛳᶧ䩽㰿ǃ↯佪䶁 ൟ㒓㰿੠कѠᣛ㙴䌒㄀㰿ˈ݊Ҫഄऎг᳒㾖ᆳࠄ㉏Ԑ 㒧ᵰ[30]DŽ

Ϣ݊ҪⷨおⳌԐˈᴀⷨおгথ⦄೼᷵ܓスⱘ㙴 䘧ᆘ⫳㰿ᛳᶧ⥛催Ѣ݊Ҫᑈ啘㒘[18]DŽ

2–4

ቕᑈ啘㒘 ᆘ⫳㰿ᛳᶧⱘ䰇ᗻ⥛гᕜ催ˈ㗠䖭ϔᑈ啘ℷ໘Ѣ݇䬂 ⱘথ㚆䰊↉DŽ㒺㰿੠कѠᣛ㙴䌒㄀㰿Џ㽕ᛳᶧ

15

ቕ ҹϟܓスˈ䖭Ϣ೼▇໻߽Ѯ㽓䚼ೳ㨫⼒ऎⱘⷨお㒧ᵰ ϔ㟈[9]DŽখϢ䇗ᶹⱘ೼᷵ܓスϢ៤Ҏ೼䩽㰿ǃ↯佪䶁 ൟ㒓㰿ᛳᶧ⥛П䯈ⱘᏂᓖ᮴㒳䅵ᄺᛣНˈԚᰃ೼᷵ܓ スⱘ↯佪䶁ൟ㒓㰿ᛳᶧᔎᑺᰒ㨫催Ѣ៤ҎDŽ

៤Ҏ䇗ᶹᇍ䈵Ёг᳝Ⳍᔧ䚼ߚᛳᶧ䩽㰿ǃ↯佪 䶁ൟ㒓㰿੠Ҏԧ㉾㉏೚㒓㰿ˈ䇈ᯢњᐌ㾘偅㰿⊏⭫೼

៤Ҏ੠ܓスЁഛᑨᓔሩDŽϢᄺ啘ܓスⳌ↨ˈ៤Ҏ䇗ᶹ ᇍ䈵Ёᛳᶧ㉾㉏೚㒓㰿ⱘ䰇ᗻ↨՟䕗Ԣˈ䖭ϔ㒧ᵰᓩ Ҏ ݇ ⊼ ˈ ಴ Ў བ ᵰ ϡ 䞛 প ᳝ ᬜ ⊏ ⭫ ˈ ㉾ ㉏ ೚ 㒓 㰿

ৃ㒜⫳ᛳᶧ[31]DŽऩࠖ䞣䰓㣃䖒૥⊏⭫ᑊϡ㛑᳝ᬜ⍜䰸 ᛳᶧ[25]DŽ

⢀াⱘ⢀ᮄᄶᄤ㰿ᛳᶧৃҹ๲ࡴҎᛳᶧⱘৃ㛑 ᗻˈҎ㉏ৃ㸼⦄Ў᮴⮛⢊ᛳᶧ៪থ⫳ர䝌ᗻ㙴♢[32]DŽ 㸔⏙⌕㸠⮙ᄺⷨお㸼ᯢ90ᑈҷ೼ᯚ຿݄ഄऎ䆹ᛳᶧ 䕗Ўᐌ㾕[32]DŽ㱑✊೼࣫䚼ഄऎⱘ䴲ೳ㨫Ҏ㕸ЁᏆ㒣 থ⦄ர䝌ᗻ㙴♢ˈԚᰃᑊ≵᳝ೳ㨫Ҏ㕸ᙷ⮙ⱘЈᑞ䆄

(6)

Surveillance and Response Journal, 2015, 6(1):44–51.

doi:10.5365/wpsar.2015.6.1.008

খ㗗᭛⤂

1. Jose DG, Welch JS. Growth retardation, anaemia and infection, with malabsorption and infestation of the bowel. The syndrome of protein-calorie malnutrition in Australian Aboriginal children.

The Medical Journal of Australia, 1970, 1:349–356.

pmid:5439141

2. Layrisse M, Roche M. The relationship between anemia and hookworm infection. Results of surveys of rural Venezuelan population. American Journal of Hygiene, 1964, 79:279–301.

pmid:14159948

3. Lucas SB et al. Aberrant form of Hymenolepis nana: possible opportunistic infection in immunosuppressed patients. Lancet, 1979, 2:1372–1373. doi:10.1016/S0140-6736(79)92859-9 pmid:92715

4. Cooper ES, Bundy DA, Henry FJ. Chronic dysentery, stunting, and whipworm infestation. Lancet, 1986, 2:280–281. doi:10.1016/

S0140-6736(86)92093-3 pmid:2874297

5. Speare R. Fatal strongyloidiasis: lessons from the literature.

In: Second National Workshop on Strongyloidiasis. Brisbane, Queensland, 2003 (http://www.jcu.edu.au/school/phtm/PHTM/ss/

acrrm-cd/CD-Index.pdf, accessed 11 February 2015).

6. Stephenson LS et al. Treatment with a single dose of albendazole improves growth of Kenyan schoolchildren with hookworm, Trichuris trichiura, and Ascaris lumbricoides infections. The American Journal of Tropical Medicine and Hygiene, 1989, 41:78–87. pmid:2764230

7. Ezeamama AE et al. Helminth infection and cognitive impairment among Filipino children. The American Journal of Tropical Medicine and Hygiene, 2005, 72:540–548. pmid:15891127

8. Elias D et al. Poor immunogenicity of BCG in helminth infected population is associated with increased in vitro TGF-beta production. Vaccine, 2008, 26:3897–3902. doi:10.1016/j.

vaccine.2008.04.083 pmid:18554755

9. Jones HI. Intestinal parasite infections in Western Australian Aborigines. The Medical Journal of Australia, 1980, 2:375–380.

pmid:7453610

10. Flannery G, White N. Immunological parameters in northeast Arnhem Land Aborigines: consequences of changing settlement patterns and lifestyles. In: Schell M, Bilsborough A, editors. Urban Ecology and Health in the Third World. Society for the Study of Human Biology Symposium Series. Melbourne, Cambridge University Press, 1993, pp. 202–220.

11. Prociv P, Luke RA. The changing epidemiology of human hookworm infection in Australia. The Medical Journal of Australia, 1995, 162:150–154. pmid:7854229

12. Hopkins RM et al. The prevalence of hookworm infection, iron deficiency and anaemia in an aboriginal community in north-west Australia. The Medical Journal of Australia, 1997, 166:241–244.

pmid:9076267

13. Fryar D, Hagan S. Pilot screening program for intestinal parasites and anaemia in adults in a Top End Aboriginal community.

Northern Territory Communicable Diseases Bulletin, 1997, 4:20–21.

14. Crowe AL et al. Decreasing prevalence of Trichuris trichiura (whipworm) in the Northern Territory from 2002 to 2012.

The Medical Journal of Australia, 2014, 200:286–289.

doi:10.5694/mja13.00141 pmid:24641155

15. van Hal SJ et al. Amoebiasis: current status in Australia.

The Medical Journal of Australia, 2007, 186:412–416.

pmid:17437396

Ⳃࠡ䖿ߛ䳔㽕䞛⫼عᒋ֗䖯੠ܼ⿟⊏⭫ㄝ㓐ড়ᗻ 䰆⊏᠟↉ᴹ䖯㸠ᆘ⫳㰿᥻ࠊDŽ݊Ёϔ乍䞡㽕᠟↉ህᰃ 䗮䖛៤Ҏ⼒ऎᬭ㚆䖯㸠⼒ऎࡼਬǃখϢ䰆⊏DŽ

ᴀⷨおЁˈḋᴀ≵᳝㒣䖛䱣ᴎᢑḋˈḋᴀ䞣䕗 ᇣˈᑊϨখϢ㗙໮Ўᮄ᢯ࢳᇍ䈵DŽ೼䇗ᶹ䖛⿟Ёˈܓ ス᠔ऴ↨՟ϡᮁব࣪˄45–70%˅ˈ⬋ཇᗻ߿↨՟г

೼ব࣪˄0.8–1.7˅DŽ⫼Ѣ↨䕗ϡৠᑈ啘ǃᗻ߿ǃ໮䞡 ᛳᶧⱘড়ᑊؐᑊ≵᳝㗗㰥䩽㰿੠㉾㉏೚㒓㰿ⱘᄷ㡖ব

࣪DŽᴹ⑤ѢعᒋЁᖗⱘ᭛ḷ䆄ᔩᑊϡᅠᭈˈ᮴⊩њ㾷 ϾҎⱘ偅㰿⊏⭫ᅲᮑᚙމ˗಴ℸ៥Ӏҙߚᵤњ⊏⭫ᑆ 乘乍Ⳃᇍᆘ⫳㰿ᙷ⮙⥛ⱘᕅડDŽ೼䇗ᶹЁᑊ᳾䆩೒ऎ ߚᮄথᛳᶧ㗙੠᮶ᕔᛳᶧ㗙DŽ

㒧䆎

ሑㅵᄬ೼䇌໮䰤ࠊˈԚᰃᴀⷨお䞡⚍থ⦄њϞϪ㑾90 ᑈҷأ䖰ೳ㨫⼒ऎᇸ݊ᰃ೼᷵ᄺ⫳Ё㙴䘧ᆘ⫳㰿ᛳᶧ ⱘᙷ⮙⥛催ˈϨ໮䞡ᆘ⫳㰿ᛳᶧ⥛催DŽ䇗ᶹ᭄᥂ᰒ

⼎ˈ䱣ⴔ↣ᑈϔ⃵ᇍܓスᓔሩऩࠖ䞣䰓㣃䖒૥⊏⭫ᑆ 乘乍Ⳃˈ䇗ᶹ㗙Ё䩽㰿⮙ⱘ䰇ᗻ⥛᳝ᰒ㨫䰡ԢˈԚᰃ

݊Ҫ⾡㉏ⱘ㙴䘧ᆘ⫳㰿⮙ᛳᶧ⥛≵᳝ᰒ㨫ব࣪DŽ䆹ग़

৆᭄᥂ᓹ㸹њ៥ӀᇍϞϪ㑾90ᑈҷ᳝䰤ⱘᆘ⫳㰿ᛳᶧ 䅸䆚ˈᑊᦤկњϢⳂࠡᚙމ䖯㸠↨䕗ⱘ෎㒓ˈՓᕫᇍ 偅㰿ᑆ乘ㄪ⬹ⱘ䆘Ԅ៤Ўৃ㛑DŽ

߽Ⲟކさ

䌘䞥ᬃᣕ

ᴀⷨお⬅

Galiwin’kude

Ngalkanbuy

عᒋЁᖗ݀݅ि⫳

ⷨお੠থሩྨਬⱘ䩽㰿⮙ⷨおϧ乍䌘䞥ᬃᣕˈ䆹䌘䞥 ᴹ⑤Ѣ೑ᆊि⫳੠ए⭫ⷨおྨਬӮ乍ⳂDŽ

Kieran Aland

㦋ᕫᯚ຿݄໻ᄺम຿ৢ༪ᄺ䞥ᬃᣕDŽ

㟈䇶

ᛳ 䇶Galiwin’ku⼒ ऎ ሙ ⇥ ᦤ կ њ ㉾ ֓ ੠ 㸔 ḋ Փ ᕫ ᴀ

ⷨおৃҹ乎߽䖯㸠˗ᛳ䇶Јᑞ⮙⧚੠एᄺⷨお᠔ⱘ

John Walker੠Rogan LeeЎᴀⷨおᦤկњ㸔⏙ᄺ㒧ᵰ

ҹঞ݋ԧ᪡԰ᮍ⊩DŽᛳ䇶David ShieldЎᴀⷨおⱘ᭄᥂

ߚᵤᦤկ㒳䅵ᄺᬃᣕDŽ ᓩ⫼ᴀ᭛ഄഔ˖

Shield J et al. Intestinal parasites of children and adults

in a remote Aboriginal community of the Northern

Territory, Australia, 1994–1996. Western Pacific

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29. Prociv P, Luke RA. Evidence for larval hypobiosis in Australian strains of Ancylostoma duodenale. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995, 89:379.

doi:10.1016/0035-9203(95)90016-0 pmid:7570868

30. Zuk M, McKean KA. Sex differences in parasite infections:

patterns and processes. International Journal for Parasitology, 1996, 26:1009–1023. doi:10.1016/S0020-7519(96)00086-0 pmid:8982783

31. Adams M, Page W, Speare R. Strongyloidiasis: an issue in Aboriginal communities. Rural and Remote Health, 2003, 3:152.

pmid:15877491

32. Prociv P. Zoonotic hookworm infections (ancylostomosis). In Palmer SR, Lord Soulsby, Simpson DIH, editors. Zoonoses:

biology, clinical practice, and public health control. Oxford, Oxford University Press, 1998, p. 803–822.

33. Currie B, Anstey N. Eosinophilic enteritis in the Northern Territory. The Medical Journal of Australia, 1991, 154:71.

pmid:1984596

34. Conner G. Diagnosis and epidemiology of Toxocara canis infection in humans (Masters of Applied Science thesis). Sydney, University of Technology, 1990.

35. Dreyer G et al. Patterns of detection of Strongyloides stercoralis in stool specimens: implications for diagnosis and clinical trials. Journal of Clinical Microbiology, 1996, 34:2569–2571.

pmid:8880521

36. Davies J et al. Hookworm in the Northern Territory: down but not out. The Medical Journal of Australia, 2013, 198:278–281.

doi:10.5694/mja12.11615 pmid:23496406

37. Kearns T et al. Faecal parasitology of human specimens collected from a remote Aboriginal community in the Northern Territory.

ASM/ACTM Poster abstract, Parasitology Masterclass 14–17 July, 2011, Cairns. Annals of the ACTM, 2011, 12:55.

38. Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology, 2000, 121 Suppl;S113–132.

doi:10.1017/S0031182000007290 pmid:11386684

39. Reynoldson JA et al. Efficacy of albendazole against Giardia and hookworm in a remote Aboriginal community in the north of Western Australia. Acta Tropica, 1998, 71:27–44. doi:10.1016/

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40. Castles I. Census counts for small areas: Northern Territory – 1991 Census of Population and Housing. Canberra, Australian Bureau of Statistics, 1993.

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17. Ali SA, Hill DR. Giardia intestinalis. Current Opinion in Infectious Diseases, 2003, 16:453–460. doi:10.1097/00001432- 200310000-00012 pmid:14501998

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