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PENGARUH PEMBERIAN EKSTRAK BUAH OKRA (Abelmoschus esculentus) TERHADAP PENINGKATAN EKSPRESI PLATELET DERIVED GROWTH FACTOR (PDGF) (Studi Eksperimental Laboratoris pada Proses Penyembuhan Luka Pasca Pencabutan Gigi Tikus Wistar dengan Diabetes Melitus

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(1)IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 63. DAFTAR PUSTAKA Abobaker, D., Edrah, S., Altwair, K. 2017. Phytochemical Screening of abelmoschus esculentus from leptis area at Al-Khums Libya. Journal International of Chemical Science; 1(2): 48-53. ADA. 2019. Diabetes Care: Standards of Medical Care in Diabetes. Journal Diabetes Care; 42(1): 513-525. Anjani, P.P., Damayanthi, E., Rimbawan., Handharyani, E. 2018. Antidiabetic Potential of Purple Okra Extract in Streptozotocin Induced Diabetic Rats. IOP Conference Series: Earth Environtment; 196. Azmi, Faidha N., Mulawarmanti D., dan Prameswari N. (2015). Efektifitas Perbandingan Kombinasi Clindamycin dan Ekstrak Nannochloropsis Oculata Terhadap Peningkatan Kepadatan Kolagen pada Osteomielitis Mandibula. Denta Jurnal Kedokteran Gigi Vol.9(1): 63-73. Barrientos, S., Stojadinovic, O., Golinko, M., Brem, H., Tomic, M. 2008. Growth factors and Cytokines in Wound Healing. Wound Repair Regeneration; 16: 585-601. Beeton, C., Garcia, A., Chandy, K. 2007. Drawing Blood From Rats Through the Saphenous Vein and by Cardiac Puncture. JoVE; 7. Bossche, J., Baardman, J., Otto, N., Velden, S., Neele, A., Berg, S., Martin, R., Chen, H., Boshuizen, M., ahmed, M., Hoeksema, M., Vos, A., Winther, M. 2016. Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages. Cell Reports; 17: 684-696. Chaeriyana, R., Ridho, F., Bandriananto, D. 2013. Peningkatan Jumlah Pembuluh Darah akibat Aplikasi Graft Hidrogel-CHA pada Soket pasca Pencabutan Gigi (Kajian in vivo). BIMKGI; 1(2): 14-18. Chanchal, D., Alok, S., Kumar, M., Bijauliya, R., Rashi, S., Gupta, S. 2018. A Brief Review On Abelmoschus Esculentus Linn Okra. IJPSR; 9(1): 58-66. Chen, P. H., Chen, X., He, X. 2014. Platelet-Derived Growth Factors and Their Receptors: Structural and Functional Perspectives. Journal Biochim Biophys Acta; 1834(10): 2176-2186. Demidova, T., Durham, J., Herman, I. 2012. Wound Healing Angiogenesis: Innovations and Challenges in Acute and Chronic Wound Healing. Advances in Wound Care; 1(1): 17-22. Devasena, T., Durga, M., Nathiya, S. 2014. Immunomodulatory and Antioxidant Actions of Dietary Flavonoids. IJPPS; 6(2): 50-55. 63. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(2) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 64. Dinh, T., Elder, S., Veves, A. 2011. Delayed Wound Healing in Diabetes: Considering Future Treatments. Diabetes Manage; 1(5): 509-519. Eming, S., Krieg, T., Davidson, J. 2007. Inflammation in Wound Repair: Molecular and Cellular Mechanisms. Journal of Investigative Dermatology; 127: 514-525. Ernawati, D.S. and Sari, A.P. 2018. Expression of Vascular endothelial Growth Factor and Matrix Metalloproteinase-9 in Apis mellifera Lawang Propolis extract Gel-treated Traumatic Ulcers in Diabetic Rats. Journal Veterinary World; 11(3): 304-309. Farooqui, M.B., Khasim, S. M., Rafiq, M., Khan, A. A. 2018. Evaluation of Wound Healing Activity of Abelmoschus Esculentus (Linn) in Albino Wistar Rats. European Journal of Pharmaceutical and Medical Research; 5(5): 508-511. Furman, B.L. 2015. Streptozotocin-Induced Diabetic Models in Mice and Rats. CurrentsProtocol Pharmacology Wiley Online Library; 70(5): 5.47.15.47.20. Gonzales, A., Andrade, Z., Costa, T., Medrado, A. 2016. Wound Healing – A Literature Review. An Bras Dermatol; 91(5): 614-20. Guo, S., Dipietro, L. 2010. Factors Affecting Wound Healing. Journal Dental Research; 89(3) : 219-29. Hady, E., Karam, S., Sawa, E., Saad, N. 2015. Expression of Vascular Endothelial Growth Factor During Healing of Extraction Sockets in Diabetic Rats. Alexandria Dental Journal; 20: 120-125. Hanafiah, O., Angga, D., Ilyas, S., Poravi, R., Abidin, T., Nainggolan, M. Syamsudin, E. 2018. The Role of TGF Beta 1 and PDGF BB in Wound Healing of the Palate. J. Advances in Health Science Research; 8: 219-226. Hasna, S. 2017. Pengaruh Pemberian Ekstrak Buah Okra (Abelmoschus esculentus) Terhadap Jumlah Sel Neutrofil. Skripsi thesis, Universitas Airlangga. Heldin, C., and Lennartsson, J. 2013. Structural and Functional Properties of Platelet Derived Growth Factor and Stem Cell Factor Receptors. Cold Spring Harbor Perspective in Biology; 3(5): 1-19 Heldin, C., Westermark, B. 1999. Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor. Physiological R; 79(4): 1284-1300.. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(3) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 65. Herin, M. 2012. Pengaruh Flavonoid Propolis Terhadap Lama Penyembuhan Luka Bakar Grade II Pada Tikus Putih. Fakultas Ilmu Kesehatan Universitas Pesantren Tinggi Darul Ulum Jombang, 1-6. Hesketh, M., Sahin, K., West, Z., Murray. 2017. Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing. International Journal of Molecular Sciences; 18: 1545-1550. Honnegowda TM, Kumar P, Udupa EG, Kumar S, Kumar U, Rao P. 2015. Role of angiogenesis and angiogenic factors in acute and chronic wound healing. Plast Aesthet Res; 2:243-9. Ikhsan, M., Purnomo, L., Mitrayana. 2010. Pengukuran Kadar Aseton Udara Nafas Sebagai Indikator Peningkatan Ketogenesis pada Penderita Diabetes Melitus Tidak Terkontrol. JKKI; 2(6): 27-30. Jarbrink, K., Ni, G., Sonnergren, H., Schmidtchen, A., Pang, A., Bajpai, R., Car, J. 2016. Prevalence and Incidence of Chronic Wounds and Related Complications: a Protocol for a Systematic Review. Systematic Reviews; 5: 152. Jin, X., Yao, T., Zhou, Z., Zhu, J., Zhang, S., Hu, W., Shen, C. 2015. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype Through activating RAGE/NF-κB Pathway. Biomed Research International; 12. Kalra, Sanjay., Bhutani, Jaikrit. 2014. Alpha Glucoside Inhibitors. Type 2 Diabetes Mellitus. Edition 1st chapter 5. Jaypee: Jaypee Publisher. Kaneko, K., Satake, C., Yamamoto, J., Takahashi, H., Sawada, S., Imai, J., Yamada, T., Katagiri, H. 2017. A Case of Idiopathic Type 1 Diabetes with Subsequent Recovery od Endogenous Insulin Secretion Despite Initial Diagnosis of Fulminant Type 1 Diabetes. Endocrine Journal; 64(3): 369374. Kementrian Kesehatan RI. 2014. Info DATIN Situasi dan Analisis Diabetes. PusdatinKemenkesRI. Kierdof, K., and Fritz, G. 2013. RAGE Regulation and Signaling in Inflammation and Beyond. Journal of Leukocyte Biology; 94: 55-68. Kolluru, G., Bir, S., Kevil, C. 2012. Endothelial Dysfunction And Diabetes: Effects On Angiogenesis, Vascular Remodelling, And Wound Healing. J International of Vascular Medicine; 1-30. Krzyszczyk P, Schloss R, Palmer A and Berthiaume F. 2018. The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes. Front Physiol; 9:419.. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(4) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 66. Kumar, D., Tony, E., Kumar, P., Kumar, K., Rao, B., Nadendla, R. 2013. A Review On: Abelmoschus Esculentus (Okra). Int. Res J Pharm; 3(4): 129132. Kumar, S., Narwal, S., Kumar, V., Prakash, O. 2011. Α-glucosidase Inhibitors from Plants: A Natural Approach to treat Diabetes. Pharmacognosy Magazine; 5(9): 19-29. Landen, N., Li, D., Stahle, M. 2016. Transition From Inflammation to Proliferation: a Critical Step During Wound Healing. Cellular and Molecular Life Sciences; 73: 3861-3885. Liao, H., Dong, W., Shi, X., Liu, H., Yuan, K. 2012. Analysis and Comparison of The Active Components and Antioxidant Activities of Extract from Abelmoschus esculentus L. Pharmacognosy Magazine; 8(30): 156-161 Liao, H., Dong, W., Shi, X., Liu, H., Yuan, K. 2012. Analysis and Comparison of The Active Components and Antioxidant Activities of Extracts From Abelmoschus esculentus L. Pharmacognosy Magazine; 8(30): 156-161. Liu, Y., Tang, J., Hu, Q., Lu, K., Hou, C. 2018. A Preliminary Study on The Expression and Clinical Value of Platelet-derived Growth Factor BB, Hypoxia Inducible Factor-1α and C-C Motif Chemokine Receptor-2 in Peripheral. Blood. During. The. Pathogenesis. of. Grave’s. Disease.. Endokrynologia Polska; 69(1): 9-15. Macleod, A. And Mansbridge, J. 2015. The innate Immune System in Acute and Chronic Wounds. Advances in Wound Care; 5(2): 65-78. Mawarti, H. 2012. Pengaruh flavonoid propolis terhadap lama penyembuhan luka bakar tikus putih. Univ. Darul Ulum Jombang. Menon, S., Flegg, J., McCue, S., Schugart, R., Dawson, R., McElwain, S. 2012. Modelling Interaction of Keratinocytes and Fibroblasts During Normal and Abnormal Wound Healing Processes. Proceedings Royal Society; 279: 3329-3338. Miyajima, K., Teoh, S., Yamashiro, H., Shinohara, M., Fatchiyah, F., Ohta, T., & Yamada, T. 2018. Effects on Glycemic Control in Impaired Wound Healing in Spontaneously Diabetic Torii (SDT) Fatty Rats. Medical Archives, 72(1):p. 4, 7 Muhammad, I., Matazu, K., Yaradua, A., nasir, A., Matazu, N., Zainab, A., Abdul, M., Bilbis, L., Abbas, A. 2017. Antidiabetic Activity of Abelmoschus esculentus (Ex- Maradi Okra) Fruit in Alloxan-induced. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(5) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 67. Diabetic Rats. Nigerian Journal of Biochemistry and Molecular Biology; 32(1): 44-52. Murraile, E., Leo, O., Moser, M. 2014. Th1/Th2 Paradigm Extended: Macrophage Polarization as an Unappreciated Pathogen-driven Escape Mechanism?. Frontiers In Imunnology; 5(603): 1-12. Okizaki, S., Ito, Y., Hosono, K., Oba, K., Ohkubo, H., Amano, H., Shichin, M., Majima, M. 2015. Supressed Recruitment of Alternatively Activated Macrophages Reduces TGF-β1 and Impairs Wound Healing in Streptozotocin-induced Diabetic Mice. Biomedicine and Pharmacotheraphy; 70: 317-325. Okonkwo, U., Dipietro, L. 2017. Diabetes and Wound Angiogenesis. J Int Mol Sci; 18: 1-15. Onakpa, M. 2013. Ethnomedicinal, phytochemical and pharmacological profile of genus Abelmoschus. J Phytopharmacology; 4(3): 647-62. Oroh, C., Pangemanan, D., Mintjelungan, C. 2015. Efektivitas Lendir Bekicot Terhadap Jumlah Sel Fibroblast Pada Luka Pasca Pencabutan Gigi Tikus Wistar. Jurnal e-GiGi; 3(2): 515-20. Pang, Y., Zhang, Y., Huang, L., Xu, L., Wang, K., Wang, D., Guan, L., Zhang, Y., Yu, F., Chen, Z., Xie, X. 2017. Effects and Mechanisms of Total Flavonoids from Blumea balsamifera (L.) DC. On Skin Wound in Rats. International Journal of Molecular Sciences; 18(2766): 1-12. Parasuraman, S., Raveendran, R., Kesavan, R. 2010. Blood Sample Collection in Small Laboratory Animals. Journal of Pharmacology and Pharmacotherapeutics; 1(2): 87-93. Patel, S., Vajdy, M. 2015. Induction of cellular and molecular immunomodulatory pathways by vitamin A and Flavonoids. Expert Opin Biol Ther; 15(10): 1411-1428. Politis, C., Schoenaers, J., Jacobs, R., Agbaje, J. 2016. Wound Healing Problems in The Mouth. Frontiers in Physiology; 7(507): 1-13. Qing, Chun. 2017. The molecular biology in wound healing dan non-healing wound. J Chineese of Traumatology; 20: 189-93. Rahmawati, A., Pargaputri, A., Karsini, I. 2018. Pengaruh Pemberian Ekstrak Alga Coklat Jenis Sargassum Sp. Terhadap Jumlah Makrofag Pada Proses Penyembuhan Ulkus Traumatikus. DENTA Journal; 12(1): 72-81. Ramachandran, S., Sandeep, v., Srinivas, N., Dhanaraju, M. 2010. Anti diabetic activity of abelmoschus esculentus on alloxan induced diabetic rats. RRBS; 4(3): 121-23.. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(6) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 68. Ramadhani, t., Sari, R., Widyastuti. 2016. Efektivitas Kombinasi Pemberian Minyak Ikan Lemuru (Sardinella longiceps) dan Aplikasi Hidroksiapatit terhadap Ekspresi FGF-2 pada Proses Bone Healing. DENTA Journal; 10(1): 20-30. Rathee, P., Chaudhary, H., Rathee, S., Kumar, V., Kohli, K. 2009. Mechanism of Action of Flavonoids as Anti-inflammatory Agents: A Review. J. Inflammation dan Allergy; 8(3): 229-235. Richard I.G. Holt., Clive S. Cockram., Allan Flyvbjerg., Barry J. Goldstein. 2017. Diabetes. Edisi 5. Singapore: Markono Printed Media. Roy, A., Shrivastava, S., Mandal, S. 2014. Functional properties of Okra Abelmoschus esculentus L. (Moench): traditional claims and scientific evidences. Plant Science Today; 1(3): 121-130. Safari, M., Ghahari, L., Zoroufchi, B. 2014. Effects of Epidermal Growth Factor, Platelet Derived Growth Factor, and Growth Hormone on Cltured rat Keratinocytes Cells in vitro. Pakistan Journal of Biological Sciences; 17(7): 931-936. Saputra, N., Suartha, I., Dharmayudha, A. 2018. Agen Diabetogenik Sterptozotocin untuk Membuat Tikus Putih Jantan Diabetes Melitus. Buletin Veteriner Udayana; 10(2); 116-121. Sen, C., Gordillo, G., Roy, S., Kirsner, R., Lambert, L., Hunt, T., Gottrup, F., Gurtner, G., Longaker, M. 2009. Human Skin Wounds: A Major and Snowballing Threat to Public Health and The Economy. Wound Repair Regen; 17(6): 763-771. Shah, B., Seth, A. 2010. Anti Inflammatory Activity Of Fruits Of Abelmoschus esculentus. J Pharmacologyonline; 1: 208-12. Shaterian, A., Borboa, A., Sawada, R., Costantini, T., Potenza, B., Coimbra, R., Eliceiri, B. 2009. Real-time analysis of the kinetics of angiogenesis and vascular permeability in an animal model of wound healing. Burns, 35(6), 811–817. Sridhar, N., Duraisingh, B., Gowtham, L., Shakthi, M., Saravanan, T. 2015. Does Diabetes Delay The Process of Wound Healing-Know How and Why?. IAJPR: 5(6): 2435-2441. Sula,. SKRIPSI. B., Deveci, E., Ozevren, H., Ekinci, C., Elbey, B. 2016. Immunohistochemical and Histopathological Changes in the Skin of Rats After Administration of Lead Accute. Journal International Morphol; 34(3): 918-922.. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

(7) IR - PERPUSTAKAAN UNIVERSITAS AIRLANGGA 69. Takeda, Y., Shimomura, T., Asao, H., Wakabayashi, I. 2017. Relationship between Immunological Abnormalities in Rat Models of Diabetes Melitus and the Amplification Circuits for Diabetes. Journal of Diabetes Research. Talubmook C, dan Buddhakala, N. 2013. Bioactivities of Extracts from Tinospora Crispa Stems, Annona Squamosa Leaves, Musa Sapientum Flowers, and Piper Sarmentosum Leaves in Diabetic Rats. Journal of Advancements in Research & Technology, 2(6):14. Tamara, A., Rochmah, Y., Mujayanto, R. 2014. Pengaruh Aplikasi Virgin Coconut Oil Terhadap Peningkatan Jumlah Fibroblas Pada Luka Pasca Pencabutan Gigi Pada Rattus Novergicus. ODONTO Dental Journal; 1(2): 29-34. Tian, Z.H., Miao, F.T., Zhang, X., Wang, Q.H., Lei, N., Guo, L.C. 2015. Therapeutic Effect of Okra Extract on Gestational Diabetes Melitus Rats Induced by Streptozotocin. Asian Pacific Journal of Tropical Medicine; 8(12): 1038-1042. Tkalcevic, V., Cuzic, S., Parnham, M., Pasalic, I., Braisa, K. 2009. Differential Evaluation of Excisional Non-occluded Wound Healing in db/db Mice. Toxicology Pathology; 37: 183-192. Velnar, T., Bailey, T., Smirkolj, V. 2009. The Wound Healing Process: an Overview of the Cellular and Molecular Mechanisms. J International Medical Research; 37: 1528-1542. WHO.2016. Global Report on Diabetes. France: WHO. William, W., Vincent, W. 2003. Angiogenesis: A Control Point for Normal and Delayed Wound Healing dan The Biology of PDGF and Other Growth factors in Wound Neovascularization. USA: Dowden Health Media. Winarsih W, Wientarsih I, dan Sutardi LN. 2012. Aktivitas Salep Ekstrak Rimpang Kunyit dalam Proses Penyembuhan Luka pada Mencit yang Diinduksi Diabetes. Jurnal Veteriner; 13(3): 242-250. Yang, L.Y., Yin, Y. C., Chin, H. L., Heng, S. S., Wai, S. Y. 2014. Effectiveness of Maceration Periods with Different Extraction Solvents on in-vitro Antimicrobial Activity from Fruit of Momordica charantia L. Journal of Applied Pharmaceutical Sciences; 4(10): 16-23. Yu, E., Min, H., An, S., Won, H., Hong, J., Hwang, E. 2008. Regulatory Mechanisms of IL-2 and IFN-γ Supression by Quercetin in T Helper Cells. Biochemical Pharmacology; 76: 70-78. Zhao, R., Liang, H., Clarke, E., Jackson, C., Xue, M. 2016. Inflammation in Chronic Wounds. International Journal of Molecular Sciences; 17(2085): 1-14.. SKRIPSI. PENGARUH PEMBERIAN EKSTRAK .... AISYAH EKASARI.

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