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REVIEW SENYAWA ANTIBAKTERI PADA KOPI SANGRAI BACHELOR THESIS Submitted in partial fulfilment of the requirements for a Food Technology Bachelor’s degree in Faculty of Agricultural Technology By: WEBIANA LOWISIA 14.I1.0111

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ANTIBACTERIAL COMPOUNDS OF ROASTED COFFEE: A REVIEW

REVIEW SENYAWA ANTIBAKTERI PADA KOPI SANGRAI

BACHELOR THESIS

Submitted in partial fulfilment of the requirements for a Food Technology

Bachelor’s degree in Faculty of Agricultural Technology

By:

WEBIANA LOWISIA

14.I1.0111

DEPARTMENT OF FOOD TECHNOLOGY

FACULTY OF AGRICULTURAL TECHNOLOGY

SOEGIJAPRANATA CATHOLIC UNIVERSITY

SEMARANG

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STATEMENT OF THESIS AUTHENTICITY

I hereby declare that the bachelor thesis entitled “

ANTIBACTERIAL

COMPOUNDS OF ROASTED COFFEE: A REVIEW

” contains no work that

ever proposed to acquire a bachelorship title in a University, and along to my

knowledge, there is no work ever written or published by others, except the ones

used as references in this thesis and mentioned in the list of references.

If it is proven in the future that partially or whole thesis is the result of

plagiarism, therefore I am willing to be revoked with all the consequences in

accordance with the law and regulations applied at Soegijapranata Catholic

University and/or valid law and regulations.

Semarang, February 2018

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ANTIBACTERIAL COMPOUNDS OF ROASTED COFFEE: A REVIEW

REVIEW SENYAWA ANTIBAKTERI PADA KOPI SANGRAI

BACHELOR THESIS

Submitted in partial fulfilment of the requirements for a Food Technology

Bachelor’s degree in Faculty of Agricultural Technology

By:

WEBIANA LOWISIA

14.I1.0111

This thesis has been approved and defended in front of the examination

committees on February 2

th

2018

Semarang, 23 February 2018

Faculty of Agricultural Technology

Soegijapranata Catholic University

Supervisor

Dean

Dr. Ir. Lindayani, MP

Dr. R. Probo Y. Nugrahedi, STP., MSc.

Co-Supervisor

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i

SUMMARY

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ii RINGKASAN

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iii

ACKNOWLEDGEMENT

Praise the Lord because of His grace and blessing that the author able to complete the thesis entitled: “ANTIBACTERIAL COMPOUNDS OF ROASTED COFFEE: A REVIEW”. This thesis was written to fulfil the requirement to acquire Bachelor Degree of Food Technology in Soegijapranata Catholic University, Semarang, Indonesia. The author would like to express sincere gratitude to all people who have given support and guidance. They are:

1.

Dr. R. Probo Y. Nugrahedi, STP., MSc. As the Dean of Faculty of Agricultural

Technology for giving the opportunity to finish the review.

2. Dr. Ir. Lindayani, MP as supervisor and Dr. R. Probo Y. Nugrahedi, STP., MSc. as co-supervisor for giving the great guidance during the process.

3. All lectures in Food Technology Department for giving all great lessons during the learning activities.

4. All administration staffs for providing great services and information during the learning activities.

5. Author’s parents (Aryani Ng), uncle Agung Budiman), aunt (Yunita Ng), cousin (Frederika Irdianti Augusta) and grandmother (Liani Wijaya) for always supporting and cheering for the author everyday.

6. Author’s boyfriend (Ricky Kurniawan) for always supporting, cheering and helping with anything author needed.

7. Marcellina Citraswara, Verlencia Anggrian, Jessica Astelia, Ira Yuliani, Ruth Jeane, Nike Chandrawibowo, Vania Junianti, Shannon Setioso, Nandya Putriani, and all friends that cannot be mentioned one by one who always support and accompany author during campus life.

The author realizes that there were unintended errors in writing this report. The author really allows all readers to give suggestions to improve its content. However, the author hopes that this report can be an inspiration and provide useful information for others.

Semarang, February 2018 Author,

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iv

3.1. Roasted Coffee Composition Related to Antibacterial Activity ... 10

3.2. General Antibacterial Activity of Roasted Coffee ... 13

3.3. Antibacterial Compounds ... 20

3.3.1. Phenolics ... 20

3.3.2. Melanoidin ... 30

3.3.3. Caffeine ... 35

3.3.4. Other Maillard reaction compounds ... 39

3.4. Synergism Interaction on Antibacterial Compounds ... 42

4. CONCLUSION AND SUGGESTIONS ... 44

4.1. Conclusion ... 44

4.2. Further Study ... 44

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v

LIST OF TABLES

Table 1. Roasted Coffee Antibacterial Activity toward Numerous Strains of Bacteria . 13

Table 2. Difference of Roasting Degree in Different Coffee Variety ... 19

Table 3. Phenolic Antibacterial Activity toward Numerous Bacteria ... 23

Table 4. Minimum Inhibition Concentration of Melanoidin... 31

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vi

LIST OF FIGURES

Figure 1. Fishbone of Conceptual Design ... 8

Figure 2. Roasted Coffee Composition Based on Molecular Weight ... 10

Figure 3. Hydroxycinammic Acid Inhibition Toward E. coli ... 29

Gambar

Table 5. Caffeine Antibacterial Activity toward Numerous Bacteria ..........................
Figure 4. Melanoidin Antibacterial Activity Mechanisms (Siderophore Strain) ..........

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