Karakteristik Penderita Systemic Lupus Erythematosus (SLE) yang Dirawat Inap di RSUP H. Adam Malik Medan Tahun 2011-2015

(1)

Universitas Sumatera Utara

Lampiran 1 : Master Data

No. U JK Ag Pdk Pkr SP DA M1 M2 M3 M4 M5 M6 M7 M8 M9 MKK RPO PM LR KSP SB

1. 19 2 1 4 1 1 2 1 1 1 0 0 0 1 0 0 2 1 2 8 1 1

2. 42 2 3 4 5 2 2 1 1 1 0 0 0 1 1 0 2 1 2 13 1 2

3. 39 2 2 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 15 1 1

4. 14 2 1 2 1 1 1 1 1 1 0 0 0 1 0 0 2 1 2 11 1 2

5. 32 2 1 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 10 1 1

6. 29 2 1 4 5 1 1 1 1 1 0 0 1 0 0 0 2 1 2 17 3 1

7. 37 2 1 4 1 2 2 1 1 1 0 1 0 1 0 0 2 1 2 2 3 2

8. 34 2 1 4 2 2 2 1 1 1 0 0 0 0 0 0 2 1 2 17 1 1

9. 25 2 1 4 5 1 2 1 1 0 0 0 0 1 0 0 2 1 2 3 1 2

10. 9 2 3 1 1 1 2 1 1 1 0 0 0 0 0 0 2 1 2 10 1 2

11. 14 2 1 2 1 1 2 1 1 1 0 0 0 0 0 0 2 1 2 9 1 1

12. 18 2 2 4 1 1 2 1 1 1 0 0 0 0 3 0 2 1 2 2 3 1

13. 21 2 1 3 2 2 2 1 1 0 0 0 0 1 0 1 2 1 2 14 3 2

14. 25 2 2 4 3 1 2 1 1 1 0 0 0 1 0 0 1 1 1 5 1 1

15. 14 2 1 2 1 1 2 1 1 1 0 0 0 0 0 0 2 1 2 3 3 1

16. 14 2 1 2 1 1 2 1 1 1 1 0 0 1 0 0 2 2 2 9 3 1

17. 26 2 3 4 5 1 2 1 1 1 0 0 0 0 0 0 2 1 2 14 1 1

18. 32 2 1 4 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 3 1 1

19. 21 2 1 4 5 2 2 1 1 1 0 0 0 0 0 0 1 1 1 7 1 2

20. 18 2 1 3 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 7 1 1

21. 21 2 1 4 5 1 2 1 1 1 0 0 1 1 0 0 2 1 2 1 3 1

22. 19 2 1 3 1 1 2 1 1 0 0 0 0 1 0 0 2 1 2 9 3 1

23. 16 2 2 3 1 2 2 1 1 1 0 0 0 0 0 0 2 1 2 3 1 2

24. 39 2 1 4 2 3 1 1 1 1 0 0 0 0 0 0 2 1 2 8 1 1

(2)

25. 12 2 1 1 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 2 1 1

26. 27 2 2 4 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 3 2 2

27. 26 2 1 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 21 1 1

28. 16 2 1 3 1 1 2 1 1 0 0 0 0 0 0 0 1 1 1 7 1 1

29. 11 1 2 1 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 8 1 1

30. 20 2 2 3 5 1 1 1 1 1 0 0 0 1 0 0 2 1 2 4 2 1

31. 20 2 2 4 5 1 2 1 1 1 0 0 0 0 0 0 2 1 2 8 1 1

32. 22 2 1 4 1 1 2 1 1 1 0 0 1 1 0 0 2 1 2 31 3 1

33. 41 2 2 4 3 2 2 1 1 1 0 0 0 1 0 0 2 1 2 7 2 1

34. 41 2 1 2 5 2 2 1 1 1 0 0 0 1 0 0 2 1 2 16 1 1

35. 18 2 1 4 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 6 2 1

36. 55 2 1 4 2 3 2 1 1 1 0 0 0 0 0 0 2 1 2 17 1 1

37. 17 2 1 2 5 1 2 1 1 1 0 1 0 0 0 0 2 1 2 19 1 1

38. 11 2 1 1 1 1 1 1 1 1 0 0 0 0 0 0 2 1 2 17 1 1

39. 25 2 2 4 5 1 2 1 1 1 0 1 0 0 0 0 2 1 2 11 1 1

40. 48 2 2 4 3 2 2 1 1 1 0 0 0 1 0 0 2 1 2 14 1 1

41. 15 2 2 2 1 1 2 1 1 1 0 1 0 1 0 0 2 1 2 3 3 2

42. 33 2 2 4 2 2 1 1 1 1 1 0 1 0 0 0 2 1 2 4 2 1

43. 26 2 2 3 4 1 2 1 1 1 0 0 0 0 0 0 1 1 1 8 1 1

44. 27 2 1 4 4 2 1 1 0 1 0 0 0 0 0 0 1 1 1 5 1 1

45. 8 2 2 1 1 1 2 1 0 0 0 1 1 0 0 0 2 1 2 19 3 1

46. 19 2 1 3 5 1 2 1 1 0 0 1 0 0 0 0 2 1 2 10 2 1

47. 19 2 3 4 1 1 1 1 1 1 0 0 0 0 0 0 1 1 1 8 1 1

48. 33 2 1 4 2 2 1 1 1 1 0 1 1 0 0 0 2 1 2 7 1 2

49. 13 2 1 1 1 1 2 1 1 1 0 0 0 1 0 0 2 2 2 19 1 1

50. 15 2 3 2 1 1 1 1 1 1 0 0 0 0 0 0 1 2 1 7 2 1

(3)

51. 15 2 1 3 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

52. 14 2 2 2 1 1 2 1 1 1 0 0 1 0 0 0 2 1 2 21 1 1

53. 18 2 1 3 1 1 2 1 1 1 0 0 1 0 0 0 2 1 2 15 1 1

54. 19 2 1 4 5 1 1 1 1 0 0 0 0 1 0 0 2 1 2 9 1 1

55. 21 2 1 4 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

56. 47 2 2 3 5 3 2 1 1 1 0 0 1 1 0 0 2 1 2 11 3 1

57. 19 2 1 4 1 1 2 1 1 1 0 0 0 1 0 0 2 1 2 13 3 1

58. 48 2 1 3 2 2 1 1 1 1 0 0 1 1 0 0 2 1 2 3 3 2

59. 45 2 1 4 5 2 2 1 1 1 0 0 0 1 0 0 2 1 2 16 1 2

60. 8 2 1 1 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

61. 28 2 2 4 2 2 1 1 1 1 0 0 0 0 0 0 1 1 1 8 1 1

62. 21 2 1 4 1 1 2 1 1 0 0 0 0 1 0 1 2 1 2 23 3 1

63. 21 2 2 4 1 1 2 1 1 1 0 0 0 1 0 0 2 1 2 22 1 1

64. 22 2 1 4 1 1 1 1 1 1 0 0 1 1 0 1 2 1 2 1 3 2

65. 19 2 1 4 1 1 1 1 1 0 0 1 0 1 0 0 2 1 2 20 3 1

66. 20 2 1 4 1 1 1 1 1 1 0 0 0 1 0 1 2 1 2 21 3 1

67. 46 2 1 4 2 2 1 1 1 1 0 0 0 0 0 0 1 1 1 7 1 1

68. 29 2 1 4 5 2 2 1 1 1 0 0 1 1 0 0 2 1 2 36 3 1

69. 13 2 2 2 1 1 2 1 1 1 0 1 1 1 0 0 2 1 2 13 3 1

70. 48 2 2 3 2 2 2 1 1 1 0 0 1 1 1 0 2 1 2 2 3 1

71. 15 2 2 2 1 1 2 1 1 1 0 0 1 0 0 0 2 1 2 11 1 1

72. 38 2 2 4 5 2 2 1 1 1 0 0 0 1 1 0 2 1 2 7 3 1

73. 15 2 2 2 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 5 1 1

74. 17 2 2 2 1 1 2 1 1 0 0 0 1 0 0 0 2 1 2 16 1 1

75. 24 2 1 4 5 1 2 1 1 1 0 0 0 0 0 0 1 1 1 2 2 1

76. 36 2 2 4 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

(4)

77. 50 2 1 3 3 2 2 1 1 1 0 1 0 1 0 0 2 1 2 14 3 1

78. 18 2 3 3 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 3 1 1

79. 30 2 1 4 2 2 2 1 1 1 0 1 1 1 0 0 2 1 2 5 3 1

80. 47 2 1 4 5 2 1 1 1 1 0 0 1 1 1 0 2 1 2 6 3 1

81. 12 2 1 1 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 7 1 1

82. 43 2 1 4 5 2 1 1 1 1 0 0 1 1 0 0 2 1 2 18 3 1

83. 46 1 1 4 5 2 2 1 1 1 0 1 1 1 0 1 2 1 2 5 3 1

84. 28 2 2 4 2 2 2 1 1 1 0 1 0 1 0 1 2 1 2 20 3 1

85. 19 2 2 4 1 1 2 1 1 1 0 0 0 0 0 0 1 1 1 8 2 1

86. 24 1 2 4 5 1 2 1 1 1 0 0 0 0 0 0 1 1 1 6 2 1

87. 39 2 2 3 2 2 2 1 1 0 0 0 0 0 0 0 1 1 1 1 2 2

88. 46 2 2 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 18 2 1

89. 28 2 2 4 3 1 2 1 1 1 0 1 0 0 0 0 2 1 2 11 3 1

90. 24 2 1 3 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

91. 35 2 2 4 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 3 2 2

92. 65 1 1 2 4 2 2 1 1 1 0 0 0 1 0 0 2 1 2 11 1 1

93. 12 2 3 1 1 1 2 1 1 1 0 0 0 1 0 0 2 1 2 14 1 1

94. 24 2 3 3 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 4 1 1

95. 34 2 1 4 2 2 2 1 1 1 0 0 0 0 0 0 1 1 1 6 1 1

96. 18 2 1 4 1 1 1 1 1 1 0 0 0 0 0 0 1 1 1 4 2 1

97. 27 2 1 4 2 2 2 1 1 1 0 1 0 0 0 0 2 1 2 11 3 1

98. 9 2 1 1 1 1 2 1 1 1 0 1 0 0 0 0 2 1 2 11 2 1

99. 19 2 1 4 1 1 1 1 1 1 1 1 1 1 0 0 2 1 2 2 3 1

100. 32 2 2 4 2 2 2 1 1 1 0 0 1 0 0 0 2 1 2 9 1 1

101. 24 2 1 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 11 2 1

102. 22 2 1 4 1 1 2 1 1 1 0 0 1 1 0 1 2 1 2 7 3 2

(5)

103. 62 2 2 3 2 3 2 1 1 1 0 1 0 0 0 0 2 1 2 10 1 1

104. 30 2 1 4 2 2 2 1 1 1 0 0 1 0 0 0 2 1 2 3 3 1

105. 14 2 1 2 1 1 1 1 1 1 0 0 0 1 0 0 2 1 2 7 1 1

106. 15 2 2 2 1 1 1 1 1 1 0 1 0 0 0 0 2 1 2 7 1 1

107. 17 2 2 3 1 1 1 1 1 1 0 0 0 1 0 0 2 1 2 17 1 1

108. 10 2 1 1 1 1 1 1 1 1 0 1 1 1 0 0 2 1 2 25 3 1

109. 21 2 1 4 5 1 2 1 1 1 0 0 1 0 0 0 2 1 2 13 1 1

110. 30 2 1 2 2 2 1 1 1 1 0 0 0 0 0 0 1 1 1 3 1 1

111. 16 2 1 3 1 1 2 1 1 1 0 1 1 1 0 1 2 1 2 6 3 2

112. 25 2 2 4 2 2 2 1 1 1 0 0 1 1 0 0 2 1 2 16 1 1

113. 22 2 2 4 1 1 2 1 1 1 0 0 1 0 0 0 2 1 2 18 1 1

114. 38 2 1 4 2 2 1 1 1 1 0 1 1 1 0 1 2 1 2 4 3 2

115. 30 2 1 4 2 2 2 1 1 1 0 0 0 1 0 0 2 1 2 9 1 2

116. 22 2 1 4 5 2 2 1 1 1 0 0 1 0 0 0 2 1 2 13 1 2

117. 16 2 2 2 1 1 2 1 1 1 0 1 0 1 0 0 2 1 2 3 2 2

U : Umur M9 : Manifestasi Gastrointestinal

JK : Jenis Kelamin M5 : Manifestasi Paru

Ag : Agama M6 : Manifestasi Ginjal

Pdk : Pendidikan M7 : Manifestasi Hematologik

Pkr : Pekerjaan M8 : Manifestasi Susunan Saraf

SP : Status Perkawinan MKK : Manifestasi Klinis Kategorik

DA : Daerah Asal RPO : Riwayat Penggunaan Obat

M1 : Manifestasi Konstitusional PM : Penatalaksanaan Medis

M2 : Manifestasi Muskuloskeletal LR : Lama Rawatan

M3 : Manifestasi Kulit KSP : Keadaan Sewaktu Pulang

M4 : Manifestasi Kardiovaskuler SB : Sumber Biaya

(6)

Lampiran 2 : Output Analisa Data A. Deskriptif

1. Sosiodemografi a. Umur

Umur

Frequency Percent Valid Percent Cumulative Percent

b. Jenis Kelamin

JenisKelamin

d. Pendidikan

Pendidikan

Valid

Tidak/Belum Sekolah 11 9.4 9.4 9.4 Pendidikan dasar

(SD/MI/sederajat)

18 15.4 15.4 24.8

Pendidikan menengah (SMP/MTs/sederajat)

21 17.9 17.9 42.7

Pendidikan tinggi

(SMA/MA/sederajat dan PT)

67 57.3 57.3 100.0

Total 117 100.0 100.0

e. Pekerjaan

Pekerjaan

(7)

f. Status Perkawinan

Status Perkawinan

Daerah Asal

Valid

Kota Medan 27 23.1 23.1 23.1

Luar Kota Medan 90 76.9 76.9 100.0

Total 117 100.0 100.0

h. Rata-rata Umur

Statistics

Std. Deviation 11.778 Variance 138.716

Minimum 8

Maximum 65

a. Multiple modes exist. The smallest value is shown

2. Manifestasi Klinis

a. Manifestasi Konstitusional

Manifestasi Konstitusional

Frequency Percent Valid Percent Cumulative Percent Valid Ada 117 100.0 100.0 100.0

b. Muskuloskeletal

Manifestasi Muskuloskeletal

Valid

Tidak ada 2 1.7 1.7 1.7

Ada 115 98.3 98.3 100.0

Total 117 100.0 100.0

c. Manifestasi Kulit

Manifestasi Kulit

Valid

Tidak ada 11 9.4 9.4 9.4

Ada 106 90.6 90.6 100.0

Total 117 100.0 100.0

(8)

d. Manifestasi Kardiovaskuler

Manifestasi Kardiovaskuler

Valid

Tidak ada 114 97.4 97.4 97.4

Ada 3 2.6 2.6 100.0

Total 117 100.0 100.0

e. Manifestasi Paru

Manifestasi Paru

Valid

Tidak ada 94 80.3 80.3 80.3

Ada 23 19.7 19.7 100.0

Total 117 100.0 100.0

f. Manifestasi Ginjal

Manifestasi Ginjal

Valid

Tidak ada 86 73.5 73.5 73.5

Ada 31 26.5 26.5 100.0

Total 117 100.0 100.0

g. Manifestasi Hematologik

Manifestasi Hematologik

Valid

Tidak ada 63 53.8 53.8 53.8

Ada 54 46.2 46.2 100.0

Total 117 100.0 100.0

h. Manifestasi Saraf

Manifestasi Saraf

Valid

Tidak ada 112 95.7 95.7 95.7

Ada 5 4.3 4.3 100.0

Total 117 100.0 100.0

i. Manifestasi Gastrointestinal

Manifestasi Gastrointestinal

Valid

Tidak ada 108 92.3 92.3 92.3

Ada 9 7.7 7.7 100.0

Total 117 100.0 100.0

3. Derajat Manifestasi

Manifestasi Klinis

Valid

Manifestasi Ringan 32 27.4 27.4 27.4 Manifestasi Berat 85 72.6 72.6 100.0

Total 117 100.0 100.0

(9)

4. Riwayat Penggunaan Obat-obatan

Riwayat Penggunaan Obat

Valid

Tidak ada 114 97.4 97.4 97.4

Ada 3 2.6 2.6 100.0

Total 117 100.0 100.0

5. Penatalaksanaan Medis

Penatalaksanaan Medis

Valid

Terapi Konservatif 32 27.4 27.4 27.4 Terapi Agresif 85 72.6 72.6 100.0

Total 117 100.0 100.0

6. Rata-rata Lama Rawatan

Statistics

Std. Deviation 6.663 Variance 44.390

Range 35

Minimum 1

Maximum 36

Sum 1152

a. Multiple modes exist. The smallest value is shown

7. Keadaan Sewaktu Pulang

Keadaan Sewaktu Pulang

Valid

Pulang Berobat Jalan 64 54.7 54.7 54.7 Pulang AtasPermintaan

Sendiri

17 14.5 14.5 69.2

Meninggal 36 30.8 30.8 100.0

Total 117 100.0 100.0

8. Sumber Biaya

Sumber Biaya

Valid

Mandiri 95 81.2 81.2 81.2

Non-Mandiri 22 18.8 18.8 100.0 Total 117 100.0 100.0

(10)

B. Bivariat

1. Derajat Manifestasi Klinis berdasarkan Umur

Manifestasi Klinis * Umur Crosstabulation

Umur Total <24 tahun >=24 tahun

Manifestasi Klinis

Manifestasi Ringan

Count 20 12 32

% within Manifestasi Klinis

62.5% 37.5% 100.0 %

Manifestasi Berat

Count 46 39 85

54.1% 45.9% 100.0 %

Total

Count 66 51 117

56.4% 43.6% 100.0 %

Chi-Square Tests Value df Asymp. Sig.

Continuity Correctionb .367 1 .545

Likelihood Ratio .670 1 .413 .531 .273

a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 13.95. b. Computed only for a 2x2 table

c. The standardized statistic is .812.

2. Jenis Kelamin berdasarkan Derajat Manifestasi Klinis

Manifestasi Klinis * JenisKelamin Crosstabulation

JenisKelamin Total Laki-laki Perempuan

Manifestasi Klinis

Manifestasi Ringan

Count 2 30 32

2.4% 97.6% 100.0 %

Total

Count 4 113 117

3.4% 96.6% 100.0 % Chi-Square Tests

Value df Asymp. Sig. (2-sided)

Exact Sig. (2-sided)

Continuity Correctionb .215 1 .643

Likelihood Ratio .955 1 .328 .574 .301

a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.09.

(11)

Universitas Sumatera Utara b. Computed only for a 2x2 table

c. The standardized statistic is 1.030.

3. Rata-rata Lama Rawatan Berdasarkan Derajat Manifestasi Klinis

Test Statisticsa

Lama Rawatan

Mann-Whitney U 541.500 Wilcoxon W 1069.500

Z -5.016

Asymp. Sig. (2-tailed) .000 a. Grouping Variable: Manifestasi Klinis

Descriptives

Manifestasi Klinis Statistic Std. Error

Lama Rawatan

Manifestasi Ringan

Mean 5.09 .366

95% Confidence Interval for Mean

Lower Bound 4.35

Upper Bound 5.84

5% Trimmed Mean 5.14

Median 5.00

Variance 4.281

Std. Deviation 2.069

Minimum 1

Maximum 8

Range 7

Interquartile Range 4

Skewness -.064 .414

Kurtosis -1.160 .809

Manifestasi Berat

Mean 11.64 .751

95% Confidence Interval for Mean

Lower Bound 10.14

Upper Bound 13.13

5% Trimmed Mean 11.27

Median 11.00

Variance 47.877

Std. Deviation 6.919

Minimum 1

Maximum 36

Range 35

Interquartile Range 10

Skewness .733 .261

Kurtosis .931 .517

Tests of Normality

Manifestasi Klinis Kolmogorov-Smirnova Shapiro-Wilk Statistic df Sig. Statistic df Sig.

Lama Rawatan Manifestasi Ringan .170 32 .019 .926 32 .031 Manifestasi Berat .101 85 .031 .954 85 .004 a. Lilliefors Significance Correction

(12)

4. Keadaan Sewaktu Pulang berdasarkan Derajat Manifestasi Klinis

Manifestasi Klinis * Keadaan Sewaktu Pulang Crosstabulation

Keadaan Sewaktu Pulang Total Pulang

Manifestasi Klinis

Manifestasi Ringan

Count 23 9 0 32

71.9% 28.1% 0.0% 100.0%

Manifestasi Berat

Count 41 8 36 85

48.2% 9.4% 42.4% 100.0%

Total

Count 64 17 36 117

54.7% 14.5% 30.8% 100.0%

Chi-Square Tests Value df Asymp. Sig. Fisher's Exact Test 26.792 .000

Linear-by-Linear Association 12.588b 1 .000 .000 .000 .000 N of Valid Cases 117

a. 1 cells (16.7%) have expected count less than 5. The minimum expected count is 4.65. b. The standardized statistic is 3.548.

(13)

Lampiran 3: Waktu Penelitian

No.

Kegiatan

Alokasi Waktu

Januari Pebruari Maret April Mei Juni Juli Agustus 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 1.

Pengajuan dan Persetujuan Judul

2.

Survei Pendahuluan

3.

Penyusunan Proposal

4.

Penelitian

5.

Analisa Data

6.

Penyusunan Laporan

(14)

(15)

(16)

(17)