Supplemental Digital Content file 3 - HR.pdf
S3 file. File that shows individual cases of HR on Day 2 Heart rate; HR [bpm], Healthy #1-#10
0 50 100 150
0 50 100 150
0 50 100 150 0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
#1
#2
#3
#4
#5
#6
#7
#8
#9
#10
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
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Start of CL-Ex
Heart rate; HR [bpm], Healthy #11-#20
rest 2min
4min 6min
8min 10min
12min 14min
16min 18min
20min 22min
24min 50
100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
40 60 80 100 120 140 160
0 50 100 150
0 50 100 150
#11
#12
#13
#14
#15
#16
#17
#18
#19
#20
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Heart rate; HR [bpm], Patient #1-#10
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
0 50 100 150
#1
#2
#3
#4
#5
#6
#7
#8
#9
#10
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex
Start of CL-Ex