BAB VII SIMPULAN DAN SARAN
7.2 Saran
2. Perlu dilakukan penelitian lebih lanjut dengan menggunakan suhu 780C sebagai titik didih etanol, supaya tidak terdapat sisa etanol di ekstrak.
3. Perlu dilakukan penelitian apakah ekstrak rumput laut (Kappaphycus alvarezii) dapat menghambat kerusakan hati non-alkoholik.
4. Perlu dilakukan penelitian lebih lanjut terhadap fungsi ekstrak rumput laut (Kappaphycus alvarezii) pada manusia dalam menghambat terjadinya peningkatan kadar ALT dan perlemakan hati karena alkohol.
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LAMPIRAN
Lampiran 1.
Keterangan Kelaikan Etik (Ethical Clearance)
Lampiran 2.
Persetujuan Pelaksanaan Penelitian
Lampiran 3.
Hasil Analisis Fitokimia Ekstrak Rumput Laut (Kappaphycus alvarezii)
Lampiran 4.
TABEL KONVERSI PERHITUNGAN DOSIS UNTUK BEBERAPA JENIS HEWAN DAN MANUSIA (Harmita, 2006)
Mencit 20 gr
Tikus 200 gr
Marmot 400 gr
Kelinci 1,5 kg
Kucing 2 kg
Kera 4 kg
Anjing 12 kg
Manusia 70 kg
Mencit 20 gr
1.0 7.0 12.25 27.8 29.7 64.1 124.2 387.9
Tikus 200 gr
0.14 1.0 1.74 3.9 4.2 9.2 17.8 56.0
Marmot 400 gr
0.08 0.57 1.0 2.25 2.4 5.2 10.2 31.5
Kelinci 1,5 kg
0.04 0.25 0.44 1.0 1.08 2.4 4.5 14.2
Kucing 2 kg
0.03 0.23 0.41 0.92 1.0 2.2 4.1 13.0
Kera 4 kg
0.016 0.11 0.19 0.42 0.45 1.0 1.9 6.1
Anjing 12 kg
0.008 0.06 0.1 0.22 0.24 0.52 1.0 3.1
Manusia 70 kg
0.0026 0.018 0.031 0.07 0.076 0.16 0.32 1.0
Lampiran 5.
Data Penelitian Kadar ALT dan AST
KONTROL ALT/SGPT AST/SGOT
K1 55 79
K2 59 86
K3 59 92
K4 61 113
K5 61 115
K6 67 118
K7 70 141
K8 80 142
K9 81 146
K10 81 150
K11 83 163
K12 97 165
K13 102 174
K14 121 185
K15 159 196
K16 207 210
K17 263 241
K18 305 256
PERLAKUAN ALT/SGPT AST/SGOT
P1 41 42
P2 42 67
P3 46 84
P4 51 110
P5 57 112
P6 61 118
P7 65 126
P8 68 126
P9 71 132
P10 72 132
P11 78 132
P12 78 142
P13 79 147
P14 83 152
P15 85 162
P16 87 164
P17 94 166
P18 106 178
Lampiran 6.
Data Penelitian Kuantitatif Steatosis/ Perlemakan Hati
KONTROL (K) PERLAKUAN (P)
1 102 55
2 103 58
3 104 59
4 105 61
5 105 65
6 106 66
7 107 66
8 109 68
9 109 69
10 111 69
11 113 69
12 113 69
13 113 71
14 114 72
15 116 73
16 116 73
17 119 75
18 123 77
Lampiran 7.
Hasil Analisis Data Statistik ANALISIS DESKRIPTIF
Descriptives
Kelompok Statistic Std. Error
ALT/SGPT Kontrol Mean 1.1172E2 17.46459
Median 81.0000
Variance 5.490E3
Std. Deviation 7.40960E1
Minimum 55.00
Maximum 305.00
Perlakuan Mean 70.2222 4.28140
Median 71.5000
Variance 329.948
Std. Deviation 1.81645E1
Minimum 41.00
Maximum 106.00
AST/SGOT Kontrol Mean 1.5400E2 11.91199
Median 1.4800E2
Variance 2.554E3
Std. Deviation 5.05383E1
Minimum 79.00
Maximum 256.00
Perlakuan Mean 1.2733E2 8.34509
Median 1.3200E2
Variance 1.254E3
Std. Deviation 3.54052E1
Minimum 42.00
Maximum 178.00
STEATOSIS Kontrol Mean 1.1044E2 1.38673
Median 1.1000E2
Variance 34.614
Std. Deviation 5.88340
Minimum 102.00
Maximum 123.00
Perlakuan Mean 67.5000 1.42400
Median 69.0000
Variance 36.500
Std. Deviation 6.04152
Minimum 55.00
Maximum 77.00
UJI NORMALITAS
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk Statistic Df Sig. Statistic df Sig.
ALT/SGPT Kontrol .174 18 . 200* .937 18 .512
Perlakuan .110 18 .200* .974 18 .867
AST/SGOT Kontrol .095 18 .200* .966 18 .714
Perlakuan .152 18 .200* .934 18 .226
STEATOSIS Kontrol .112 18 .200* .959 18 .587
Perlakuan .154 18 .200* .951 18 .442
a. Lilliefors Significance Correction
*. This is a lower bound of the true significance.
Uji Homogenitas & Independent T Test
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
ALT/SGPT Kontrol 18 1.1172E2 74.09597 17.46459
Perlakuan 18 70.2222 18.16446 4.28140
AST/SGOT Kontrol 18 1.5400E2 50.53828 11.91199
Perlakuan 18 1.2733E2 35.40522 8.34509
STEATOSIS Kontrol 18 1.1044E2 5.88340 1.38673
Perlakuan 18 67.5000 6.04152 1.42400