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Lampiran 2 Gambaran histologi peningkatan neoangiogenesis dan reepitelialisasi pada ulkus traumatikus mukosa mulut tikus putih jantan.
Angiogenesis Kelompok Kontrol (Povidone Iodine)
Angiogenesis Kelompok Ekstak Etanol Buah Adas (Foenicullum vulgare Mill) konsentrasi
50%
Reepitelialisasi Kelompok Kontrol (Povidone Iodine)
Reepitelialisasi Kelompok Ekstak Etanol Buah Adas (Foenicullum vulgare Mill)
konsentrasi 50%
Keterangan: Pada gambaran histologis (Gambar A, B,C, D) tampak peningkatan angiogenesis dan reepitelisasi pada kelompok Perlakuan ekstrak etanol adas (Foeniculum Vulgare) konsentrasi 50% (pengecatan Hematoxcylin Eosin. Pengambilan gambar dengan penggunaan mikroskop elektrik Olympus CX21 pembesaran 400x).
Lampiran 3. Data Hasil Penelitian
NO Perlakuan Data kuantitatif angiogenesis dan
repitelialisasi mukosa mulut tikus putih Povidone Iodine Angiogenesis
(unit)
Reepitelialisasi (μm)
1 17 2131
2 19 2056
3 18 2097
4 19 2082
5 16 1835
6 17 2163
7 15 1938
8 14 2129
9 16 2012
10 18 1892
11 15 2138
12 16 2035
13 17 1937
14 14 2160
15 18 1917
16 15 1975
Ekstrak Etanol Buah Adas (Foenicullum vulgare Mill.)
Konsentrasi 50%
Angiogenesis (unit)
Reepitelialisasi (μm)
1 40 831
2 39 1042
3 40 949
4 37 1015
5 37 997
6 42 935
7 38 887
8 36 1017
9 41 894
10 39 975
11 44 938
12 38 1057
13 40 879
14 36 1174
15 38 884
16 42 1156
Lampiran 4. Hasil analisis data dengan SPSS
Descriptives
Kelompok Statistic Std. Error
Angiogenesis Kontrol Povidone Iodine
Mean 16.5000 .40825
95% Confidence Interval for Mean
Lower Bound 15.6298 Upper Bound 17.3702
5% Trimmed Mean 16.5000
Median 16.5000
Variance 2.667
Std. Deviation 1.63299
Minimum 14.00
Maximum 19.00
Range 5.00
Interquartile Range 3.00
Skewness .000 .564
Kurtosis -1.089 1.091
Ekstrak Adas Foenicullum vulgare Mill konsentrasi 50%
Mean 39.1875 .57168
95% Confidence Interval for Mean
Lower Bound 37.9690 Upper Bound 40.4060
5% Trimmed Mean 39.0972
Median 39.0000
Variance 5.229
Std. Deviation 2.28674
Minimum 36.00
Maximum 44.00
Range 8.00
Interquartile Range 3.50
Skewness .464 .564
Kurtosis -.313 1.091
Case Processing Summary
Kelompok
Cases
Valid Missing Total
N Percent N Percent N Percent
Angiogenesis Kontrol Povidone Iodine 16 100.0% 0 .0% 16 100.0%
Ekstrak Adas
Foenicullum vulgare Mill konsentrasi 50%
16 100.0% 0 .0% 16 100.0%
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk Statistic df Sig. Statistic df Sig.
Angiogenesis Kontrol Povidone Iodine .133 16 .200* .938 16 .325 Ekstrak Adas
Foenicullum vulgare Mill konsentrasi 50%
.136 16 .200* .957 16 .608
a. Lilliefors Significance Correction
*. This is a lower bound of the true significance.
Independent Samples Test
Levene's Test for Equality of
Variances t-test for Equality of Means
F Sig. t df
Sig. (2- tailed)
Mean Differen
ce
Std.
Error Differen
ce
95% Confidence Interval of the
Difference Lower Upper Angioge
nesis
Equal variances assumed
1.488 .232 - 32.29 6
30 .000
- 22.6875 0
.70249
- 24.1221 7
- 21.2528 3 Equal
variances not assumed
- 32.29 6
27.14
1 .000
- 22.6875 0
.70249
- 24.1285 4
- 21.2464 6
Descriptives
Kelompok Statistic Std. Error
Reepitelialisasi kontrol Povidone Iodine Mean 2031.06 26.175
95% Confidence Interval for Mean
Lower Bound 1975.27 Upper Bound 2086.85
5% Trimmed Mean 2034.62
Median 2045.50
Variance 1.096E4
Std. Deviation 104.700
Minimum 1835
Maximum 2163
Range 328
Interquartile Range 193
Skewness -.365 .564
Kurtosis -1.128 1.091
Ekstrak Buah Adas Foenicullum vulgare
Mean 976.88 24.457
95% Confidence Lower Bound 924.75
Mill Konsentrasi 50% Interval for Mean Upper Bound 1029.00
5% Trimmed Mean 974.03
Median 962.00
Variance 9.570E3
Std. Deviation 97.826
Minimum 831
Maximum 1174
Range 343
Interquartile Range 147
Skewness .654 .564
Kurtosis -.074 1.091
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk Statistic df Sig. Statistic df Sig.
Reepitelialisasi kontrol Povidone Iodine .138 16 .200* .934 16 .279 Ekstrak Buah Adas
Foenicullum vulgare Mill Konsentrasi 50%
.114 16 .200* .944 16 .400
a. Lilliefors Significance Correction
*. This is a lower bound of the true significance.
Case Processing Summary
Kelompok
Cases
Valid Missing Total
N Percent N Percent N Percent
Reepitelialisasi kontrol Povidone Iodine 16 100.0% 0 .0% 16 100.0%
Ekstrak Buah Adas Foenicullum vulgare Mill Konsentrasi 50%
16 100.0% 0 .0% 16 100.0%
Independent Samples Test
Levene's Test for Equality of
Variances t-test for Equality of Means
F Sig. t df
Sig. (2- tailed)
Mean Differen
ce
Std.
Error Differen
ce
95% Confidence Interval of the
Difference Lower Upper Reepiteli
alisasi
Equal variances assumed
.368 .549 29.42
8 30 .000 1054.18
8 35.823 981.028 1127.34 7
Equal variances not assumed
29.42 8
29.86
3 .000 1054.18
8 35.823 981.014 1127.36 1
Lampiran 5. Dokumentasi Saat Penelitian
Gambar 1. Buah Adas Foenicullum vulgare Mill.
Gambar 2. Penyaringan dengan tabung Erlenmeyer
Gambar 3. Filtrat diuapkan dengan vacum rotary evaporator
Gambar 4. Ekstrak Etanol Buah Adas Foenicullum vulgare Mill.
Gambar 5. Pengolesan H2O2 30% pada Gambar 6. Ulkus Traumatikus pada