Buku Rekomendasi Obat-obatan

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w = week d = day h = hour g = gram SL = sublingual U = unit

IR = immediate release ER = extended release

EC = enteric coated sd = single dose QD = 1 dose per day

BID = divided in 2 dose per day (arti aslinya 2 kali sehari, tp biar gampang)

TID = divided in 3 dose per day QID = divided in 4 dose per day

Injeksi tanpa mL serbuk, resepkan pelarut

Ga ada keterangan administrasi = PO Ga ada keterangan waktu = per day

Mayor

IPD – Kardiovaskular

STEMI R/ Aspirin 80 mg tab No. IV S 1 dd tab IV

160-325 mg R/ Clopidogrel 75 mg tab No. IV

S 1 dd tab IV

600 mg (8 tab) if PPCI R/ ISDN SL 5 mg tab No. III

S 1 dd tab I, pro nyeri

Max 3x. CI: HR <50, >120, BP <90/60, sildenafil 24 jam

R/ Morphine sulfate inj 10 mg/mL amp No. I S pro injeksi

Ampul 1 mL, dosis 2-4 mg. Diencerkan dgn D5%

R/ Streptokinase inj 1500000 unit vial No. I S pro infus

Diikuti aspirin 325 mg/d Acute pulmonary

edema

R/ Furosemide inj 10mg/mL 2 mL amp No. II S pro injeksi

0,5-1 mg/kg IV R/ Morphine sulfate inj 10 mg/mL amp No. I

S pro injeksi

Ampul 1 mL, dosis 2-4 mg. Diencerkan dgn D5%

R/ ISDN SL 5 mg tab No. III S 1 dd tab I, pro nyeri

Max 3x. CI: HR <50, >120, BP <90/60, sildenafil 24 jam

R/ Nitroglycerine inj 1 mg/mL 10mL amp No. I S pro infus

SBP>100 mmHg, 10-20 µg/min R/ Dopamine 40 mg/mL 5mL amp No. I

S pro infus

SBP<100, shock, 5-15 µg/kg/min R/ Dobutamine 50 mg/mL 5mL amp No. I

S pro infus

SBP 70-100, no shock, 2-20 µg/kg/min R/ Norepinephrine 1 mg/mL 4mL amp No. I

S pro infus

SBP <70, 0,5-30 µg/min

CHF R/ Furosemide 40 mg tab No. VII

S 1 dd tab I

R/ Captopril 25 mg tab No. XXI S 3 dd tab I

R/ Bisoprolol 2,5 mg tab No. VII S 1 dd tab I

R/ Spironolactone 25 mg tab No. VII S 1 dd tab I

Cardiac arrest R/ Epinephrine 1:1000 1mL amp No. III S pro injeksi

Every 3-5 min R/ Amiodarone 50 mg/mL 3mL amp No. III

S pro injeksi

Bolus lambat 300 mg, 2^nd 150 mg

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AF Poli R/ Bisoprolol 2,5 mg tab No. VII S 1 dd tab I

Rujuk R/ Warfarin 2 mg tab No. VII

S 1 dd tab I

Target INR 2-2,5x Takikardia R/ Adenosine 3 mg/mL 2mL vial No. III

S pro injeksi

6 mg, 2^nd 12 mg Kardioversi:

- Narrow regular – 50-100 J

- Narrow irregular – 120-200 J or 200 J - Wide regular – 100 J

Bradikardia R/ Atropine sulfate 0,25 mg/mL 1mL amp No. VI S pro injeksi

0,5 mg repeat 3-5 min, max 3 mg R/ Dopamine 40 mg/mL 5mL amp No. I

S pro infus

2-20 µg/kg/min R/ Epinephrine 1:1000 1mL amp No. III

S pro injeksi

2-10 µg/min Frequent VES R/ Bisoprolol 2,5 mg tab No. V

S 1 dd tab I

Selective β-blocker, rujuk

APS R/ Aspirin 80 mg tab No. XXX

S 1 dd tab I

Rujuk Hipertensi R/ Hydrochlorothiazide 25 mg tab No. XXX

S 1 dd tab I

Diuretics. Indication: HF, high CAD risk, diabetes, stroke prevention R/ Spironolactone 25 mg tab No. XXX

S 1 dd tab I

Aldosterone antagonist. Indication:

HF, post AMI R/ Captopril 12,5 mg tab No. XXX

S 3 dd tab I, ac

ACE-I. Indication: HF, post AMI, high CAD risk, DM, CKD, prevent stroke R/ Valsartan 80 mg tab No. XXX

S 1 dd tab I

ARB. Indication: HF, diabetes, CKD R/ Amlopdipine 5 mg tab No. XXX

S 1 dd tab I

CCB: high CAD risk, diabetes R/ Bisoprolol 2,5 mg tab No. V

S 1 dd tab I

β-blocker: HF, post AMI, high CAD risk, diabetes

PAD R/ Cilostazol 100 mg tab No. X

S 2 dd tab I, ac

DVT R/ Heparin inj 5000 IU/mL 5mL vial No. I S pro injeksi

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IPD – Pulmonologi

Asma akut R/ Salbutamol/ipratropium bromide resp No. III S pro nebulisasi

Nebulisasi tiap 20 mnt, max 3x R/ Prednisone 5 mg tab No. X

S 1 dd tab X

Kalau ringan sedang R/ Budesonide 0,25 mg resp No. II

S pro nebulisasi

Kalau berat R/ Methilprednisolone injk 125 mg vial No. I

S pro injeksi

R/ Epinephrine inj 1:1000 1mL amp No. I S pro injeksi

Mengancam nyawa, 0,3 mL SC R/ Salbutamol inh 100 µg/spray No. I

S 1 dd puff I, prn sesak

Obat pulang

7 hari R/ Budesonide inh 200 µg/spray No. I

S 2 dd puff II

R/ Prednisone 5 mg tab No. LXX S 1 dd tab X, habiskan

Asma kronik R/ Salbutamol inh 100 µg/spray No. I S 1 dd puff I, prn sesak

Tahap 1 dan 2 R/ Budesonide inh 200 µg/spray No. I

S 2 dd puff I

Tahap 2 R/ Symbicort turbuhaler 160/4,5 µg/spray No. I

S 1 dd puff I

Tahap 3

Tahap 4 1 dd puff II

PPOK R/ NK dewasa No. I

S pro oksigenasi

Eksaserbasi akut:

Target SpO2 88-92

Ekuivalen prednisone 30 mg/d Infus 750 mg/d

R/ Salbutamol inh 2,5 mg resp No. III S pro nebulisasi

R/ Methylprednisolone inj 125 mg vial No. I S pro injeksi

R/ Levofloxacin inj 5 mg/mL 100mL fl No. II S pro injeksi

R/ Salbutamol inh 100 µg/spray No. I S 1 dd puff I, prn sesak

GOLD A (salbutamol) R/ Indacaterol swinghaler No. I

S pro inhalasi

R/ Indacaterol inh 300 µg cap No. XXX S 1 dd puff I

GOLD B (LABA)

R/ Tiotoprium bromide handihaler No. I S pro inhalasi

R/ Tiotroprium bromide inh 18 µg cap No. XXX S 1 dd I puff

GOLD C (LAMA)

R/ Symbicort turbuhaler 160/4,5 µg/spray No. I S 1 dd puff I

GOLD D (ICS + LABA) if CAT >20 Pneumonia R/ Azithromycin 500 mg capl No. III

S 1 dd tab I hari 1, 1 dd tab ½ hari 2-5

Sehat, ga ada antibiotic 3 bulan terakhir

R/ Levofloxacin 500 mg tab No. XV S 1 dd tab 1 ½, habiskan

Ada komorbid OR antibiotic last 3 month, 10 hari

R/ Levofloxacin inj 5 mg/mL 100mL fl No. II S pro injeksi

Rawat inap IV 750 mg/d Bronkhitis akut R/ Salbutamol inh 2,5 mg resp No. III

S pro nebulisasi

R/ Amoxicillin 500 mg capl No. XXI S 3 dd tab I, habiskan

7-10 hari. Tambah paracetamol Bronkiektasis R/ Amoxicillin 500 mg capl No. XXI

S 3 dd tab I, habiskan

Mild-moderate R/ Gentamicin 40 mg/mL 2mL amp No. I

S pro injeksi

Moderate-severe 3-5 mg/kg/d TID

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TB kategori 1 2RHZE/4R3H3

R/ 4KDT RHZE capl No. CXX S 1 dd tab IV, ac

R/ 2KDT RH capl No. CXX S 1 dd tab IV, ac

R: 10 (8-12) mg/kg/d, max 600 H: 5 (4-6) mg/kg/d, max 300 Z: 25 (20-30) mg/kg/d E: 15 (15-20) mg/kg/d S: 15 (12-18) mg/kg/d

BB Intensif Sisip Lanj.

30-37 2 + 500 S 2 2 + 2 E 38-54 3 + 750 S 3 3 + 3 E 55-70 4 + 1000 S 4 4 + 4 E

>70 5 + 1000 S 5 5 + 5 E R150-H75-Z400-E275

R150-H150 E400

Eg. BB = 60 kg R/ Vitamin B6 10 mg tab No. LC

S 3 dd tab I

TB kategori 2 2 RHZES/RHZE/5R3H3E3 R/ 4KDT RHZE capl No. CXX S 1 dd tab IV, ac

R/ Streptomycin inj 1g vial No. XXX S pro injeksi IM

R/ 2KDT RH capl No. CXX S 1 dd tab IV, ac

R/ Ethambutol 400 mg tab No. CXX S 1 dd tab IV, ac

INH profilaksis R/ Isoniazid 100 mg tab No. XXX S 1 dd c.orig I

BB 10 kg, profilaksis primer

Primer 10 mg/kg/d 6 mo Sekunder 5 mg/kg/d 6-9 mo R/ Vitamin B6 10 mg tab No. LC

S 3 dd tab I

IPD – Hematologi

Anemia megaloblastic

R/ Vitamin B12 500 µg/mL 1mL amp No. VII S pro injeksi

1x100 µg IM/SC 1 w, lalu 2d sekali 7 dosis, 4d sekali 2-3 w, lalu monthly R/ Vitamin B9 1 mg tab No. XXX

S 1 dd tab I

1x1-5 mg PO/IM/IV/SC, 1-4 mo Anemia pernisiosa R/ Vitamin B12 500 µg/mL 1mL amp No. II

S pro injeksi

1000 µg/mo IM seumur hidup ADB R/ Ferrous sulfate 325 mg tab No. XC

S 3 dd tab I, ac

Hingga 3 bulan Hb normal R/ Ferrous sulfate syr 15mg/5mL fl No. I

S 3 dd c.orig I, ac

Anak 3-5 mg/kg/d TID R/ Vitamin C 50 mg tab No. XC

S 3 dd tab I

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IPD – Uronefrologi

Sistitis non komplikata

R/ Ciprofloxacin 500 mg tab No. VI S 2 dd tab I, habiskan

3 hari ISK pada kehamilan R/ Amoxicillin 500 mg capl No. XXI

S 3 dd capl I, habiskan

Sistitis 5-7 hari, pyelonefritis 10-14 hari

ISK laki R/ Ciprofloxacin 500 mg tab No. XX S 2 dd tab I, habiskan

10-14 hari Pielonefritis akut R/ Ciprofloxacin 500 mg tab No. XX

Rawat jalan, 7-14 hari R/ Ciprofloxacin 2 mg/mL 100 mL fl No. IV

S pro injeksi

Rawat inap, 15 hari, 2x400 mg Prostatitis R/ Ciprofloxacin 500 mg tab No. XX

S 2 dd tab I, habiskan Epididimitis R/ Ceftriaxone 1g vial No. I

S pro injeksi

250 mg IM, sd, plus salah satu di bawah

R/ Doxycycline 100 mg cap No. XX S 2 dd cap I

10 hari. Curiga IMS (klamidia or GO) R/ Levofloxacin 500 mg tab No. X

S 1 dd tab I

10 hari. Curiga IMS (anal sex)

BPH R/ Tamsulosine 0,4 mg tab No. V

S 1 dd tab I

Selektif α-1a blocker, rujuk R/ Dutasterid 0,5 mg cap No. V

S 1 dd cap I

5-ARI, ↓ DHT dari testosteron

IPD – Rheumatologi

Rheumatoid arthritis R/ Sodium diclofenac 50 mg tab No. XIV S 2 dd tab I

R/ Meloxicam 15 mg tab No. VII S 1 dd tab I

Bila ada masalah perut R/ Prednisone 5 mg tab No. VII

S 1 dd tab I

Bridging therapy Osteoartritis NSAID spt RA

Gout akut R/ Colchicine 0,5 mg tab No. V

S 2 tab, lanjut 1 tab 1 jam kemudian

Dapat diulang tiap 2-3 h, max 6 mg R/ Indomethacin 25 mg tab No. IV

S 4 dd tab I

Kalau sudah >24h Gout kronik R/ Allopurinol 100 mg tab No. XIV

S 2 dd tab I

Polymyalgia arthritis R/ Prednisone 5 mg tab No. XXI S 3 dd tab I

12,5-25 mg/d, 2-4w, taper off

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IPD – Gastroenterologi

GERD R/ Omeprazole 20 mg caps No. XIV S 2 dd cap I

PPI test 7-14 hari Dispepsia R/ Antasida tab kunyah No. XXI

S 3 dd tab I, ac

R/ Omeprazole 20 mg caps No. VII S 1 dd cap I

Gastritis, ulkus peptikum

R/ Omeprazole 20 mg caps No. XIV S 2 dd cap I

PPI double dose R/ Omeprazole inj 40 mg vial No. III

S pro injeksi

Kalau hemel, bolus 80 mg, lanjut 8 mg/jam

H. pylori R/ Omeprazole 20 mg caps No. XXVIII S 2 dd cap I

14 hari R/ Chlarithromycin 500 mg tab No. XXVIII

R/ Amoxicillin 500 mg capl No. LVI S 2 dd tab II, habiskan

Parotitis bacterial Antipiretik, analgetik

R/ Flucloxacillin 500 mg cap No. XX S 4 dd cap I

5 hari R/ Metronidazole 500 mg tab No. XV

S 3 dd tab I

PVO R/ Somatostatin 3 mg amp No. I

S pro injeksi

250 µg IV bolus + 250 µg/h, 72h R/ Lactulose syr 10mg/15mL fl No. I

S 1 dd c.orig I

Propranolol 10 mg tab No. XIV S 1 dd tab II

Mencegah perdarahan Hemorrhoid R/ Laxadine syr fl No. I

S 1 dd c.orig I

Parafin/gliserin/fenolftalein R/ Ardium 500 mg tab No. XLII

S 3 dd tab II untuk 4 hari, lanjut 2 dd tab II untuk 3 hari, lanjut 1 dd tab II

6 tablet per hari selama 4 hari awal, lalu 4 tablet per hari diberikan selama 3 hari, dan lanjutkan 2 tablet per hari R/ Mefenamic acid 500 mg capl No. X

S 3 dd tab I, prn nyeri

Disentri amuba R/ Metronidazole 500 mg tab No. XV S 3 dd tab I

3-5 hari Disentri basiler R/ Ciprofloxacin 500 mg tab No. VI

S 2 dd tab I

3 hari R/ Cotrimoxazole susp 40/200 mg 60mL fl No. I

S 2 dd c.orig II, 3 hari

Anak (eg. 20kg), 8-40 mg/kg/d, BID Giardiasis R/ Metronidazole 500 mg tab No. X

5-7 hari Kolera R/ Tetracycline 500 mg cap No. XVI

S 4 dd cap I, habiskan

3-4 hari R/ Azithromycin syr 200mg/5mL fl No. II

S hari 1 1 ½ sendok, hari 2-5 ¾ sendok

Anak (eg. 20 kg), ibu hamil 15 mg/kg/d d1, 7,5 mg/kg/d d2-5

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IPD – Metabolik, Endokrin, Degeneratif

Grave’s disease R/ Methimazole 10 mg tab No. VII S 1 dd tab I

R/ Propylthiouracil 100 mg tab No. XXI S 3 dd tab I

Kalau hamil R/ Propranolol 10 mg tab No. XXI

S 3 dd tab I

Geri simpto OR HR >90 OR KV Krisis tiroid R/ Propylthiouracil 100 mg tab No. XII

S 6 tab, lalu 2 tab tiap 4-6 jam

PTU 600 mg, lanjut 200-250 mg tiap 4- 6 h

R/ Paracetamol 500 mg tab No. VI S 3 dd tab II

Resusitasi cairan dan elektrolit R/ Lugol sol fl No. I

S 4 dd gtt 5-10

Lugol solution 5-10 drops tiap 4-6h R/ Propranolol 10 mg tab No. XVI

S 4 dd tab IV

40-80 mg tiap 4-6 h Hipotiroid R/ Levothyroxine 50 µg tab No. V

S 1 dd tab I

Rujuk, edukasi garam beriodium, ikan, telur

R/ Lugol sol fl No. I S 4 dd gtt 5-10

Lugol solution 5-10 drops tiap 4-6h Krisis adrenal R/ NaCl 0,9% 500 cc kolf No. II

S pro infus

NS 1L/h R/ Hydrocortisone 100 mg vial No. II

S pro injeksi

Hydrocortisone 100 mg IV bolus, 100- 200 mg/d

DM tipe 2 R/ Metformin 500 mg tab No. XXI S 3 dd tab I

Biguanid: ↓ gluconeogenesis, ↑ ambilan glukosa. CI: CKD

Hipoglikemia Glukosa 15-20 gram PO Ringan

R/ Dextrose 40% 25 mL flc No. I S pro injeksi

Berat, cek GDS dalam 15 menit R/ Dextrose 10% 500 mL kolf No. I

S pro injeksi

Rumat 6 h/kolf 30kg: glukosa 9 gram, 50kg: glukosa 15 gram Anak diabetes sadar R/ Dextrose 10% 500 mL kolf No. I

S pro injeksi

Anak diabetes tidak sadar, 1-2 mL/kg bolus + 3-5 mL/kg/h

F-75 pertama atau 50cc larutan glukosa 10% Anak gizi buruk sadar R/ Dextrose 10% 500 mL kolf No. I

S pro injeksi

Anak gizi buruk letargis, 5 mL/kg Hiperglikemia R/ NaCl 0,9% 500 mL kolf No. X

S pro infus

1L/jam. Anak 10-20 mL/kg, lanjut 0,45%

R/ Regular insulin vial No. I S pro injeksi

Bolus 0,1-0,15 U/kg, lanjut 0,1 U/kg/h.

Anak 0,05-0,1 U/kg R/ KCl 7,46% 25 mL flc No. I

S pro infus

20-30 mEq/L, jika K 3,3-5 mEq/L R/ Sodium bicarbonate 84mg/mL flc No. I

S pro injeksi

100 mEq dalam 400 mL IV fluid 20 mEqk, bila pH <6,9 pada KAD Dislipidemia R/ Simvastatin 10 mg tab No. VII

S 1 dd tab I, malam

Low: LDL↓ <30%

R/ Atorvastatin 20 mg tab No. VII S 1 dd tab I, malam

Mod: LDL↓ 30-50%

R/ Atorvastatin 40 mg tab No. VII S 1 dd tab I, malam

High: LDL↓ >50%

R/ Gemfibrozil 600 mg cap No. XIV S 2 dd cap I

Triglizerid >500

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IPD – Imunologi Infeksi

HIV R/ FDC ART TDF-3TC-EFV dewasa tab No. XIV S 1 dd tab I

Tenofovir 300, Lamivudine 300, Efavirenz 600

R/ Cotrimoxazole 480 mg tab No. XXVIII S 1 dd tab II

Hingga 2 tahun / CD4 cukup Kandidosis oral R/ Nystatin drop 100.000 IU/mL fl No. I

S 3 dd 1 mL

Ringan, 10 hari R/ Fluconazole 150 mg cap No. XIV

S 1 dd cap I

Berat, 1-2 minggu Malaria falciparum R/ Dihydroartemisinin 40 mg + Piperaquine 320

mg tab No. XII S 1 dd tab IV

R/ Primaquine 15 mg tab No. III S 1 dd tab III, sd

BB = 60 kg

BB α PQ

<10 0.5 ¼

10-20 1 ¼

20-30 1.5 ½

30-40 2 ¾

40-60 3 1

>60 4 1

Primaquine falci 0,75 mg/kg sd Primaquine vivax/ovale 0,25 mg/kg/d Malaria vivax ovale R/ DHP 360 mg tab No. XII

S 1 dd tab IV

R/ Primakuin 15 mg tab No. XIV S 1 dd tab I, habiskan BB = 60 kg

Malaria hamil &

malariae

R/ DHP 360 mg tab No. XII S 1 dd tab IV

BB = 60 kg

Malaria berat R/ Artesunate inj 60 mg vial No. I S pro injeksi

0h, 12h, 24h, daily: 2,4 mg/kg IV/IM Larutin 1 mL pelarut dan 5 mL d5%

Difteria R/ Procaine benzylpenicillin inj 3 juta U vial No. I S pro injeksi IM

1,2 juta U/d, BID, IM, 14 hari R/ ADS inj 20k U 10mL vial No. I

S pro injeksi IV

Dalam 60 min

Nasal: 20k-40k U, bisa IM Fausial: 40k-60k U Berat: 80k-120k U Pertusis R/ Azithromycin 500 mg capl No. III

S 1 dd tab I hari 1, 1 dd tab ½ hari 2-5 R/ Azithromycin syr 200mg/5mL 15 mL fl No. II S 1 dd c.orig I, 5 hari

Anak: 10 mg/kg QD, 5 hari Eg. BB = 20 kg

Tetanus R/ Dextrose 5% 500 cc kolf No. I S pro infus

R/ Ringer lactate 500 cc kolf No. I S pro infus

D5%:RL 1:1 per 6 h

R/ HTIg inj 250 IU vial No. II S pro injeksi

500-3000 IU, ½ IM, ½ sekitar luka R/ Tetanus toxoid inj vial No. I

S pro injeksi

IM 0,5 mL R/ Procaine benzylpenicillin inj 3 juta U vial No. I

S pro injeksi IM

50k IU/kg/x IM, tiap 12 h, 7-10 hari R/ Metronidazole inj 5mg/mL 100 mL fl No. I

S pro injeksi

15 mg/kg, lalu 30 mg/kg/d QID, 7-10 hari

R/ Diazepam inj 5mg/mL 2mL amp No. I S pro infus

0.1-0.3 mg/kg/kali tiap 2-4 jam, 2 mg/menit max

R/ Phenobarbital inj 50 mg/mL 1mL amp No. I S pro infus

20 mg/kg, 10-20 mg/mnt

Bolus tiap kejang hingga 48 h bebas, rumat 10-12 mg/kg, DOC neonatus

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Botulism R/ Equine serum heptavalent botulinum antitoxin inj 20 mL vial No. I

S pro injeksi

Anak >1th dan dewasa, dicairkan dengan NS 1:10, 0,5 mL/min 30 min, naik 1 mL/min 30 min, lalu 2 mL/min R/ Botulism Ig inj 100 mg vial No. I

S pro injeksi

Bayi <1th, 100 mg/kg IV, 25 mg/kg/h 15 min, lalu naik 50 mg/kg/h

Leptospirosis R/ Doxycycline 100 mg cap No. XIV S 2 dd cap I, habiskan

Ringan, 7 hari R/ Procaine benzylpenicillin inj 3 juta U vial No. I

S pro injeksi IM

Berat, 4x1,5 juta U, 7 hari R/ Doxycycline 100 mg cap No. XIV

S 2 cap per minggu

Profilaksis Tifoid R/ Chloramphenicol 500 mg cap No. XL

Dewasa, 10 hari R/ Chloramphenicol susp 125mg/5mL 60 mL fl

No. VII

Anak 100 mg/kg/d QID, 10 hari Eg. BB 10 kg, 250 mg/x

R/ Amoxicillin 500 mg capl No. XXX S 3 dd capl I, habiskan

Ibu hamil, 10 hari Hookworm infection,

ascariasis

R/ Albendazole 400 mg tab No. I S 1 dd tab I, sd

Tangani anemia bila perlu Neurosistiserkosis R/ Albendazole 400 mg tab No. XX

Max 800 mg/d, 8-30 hari R/ Albendazole susp 200mg/5mL

S 2 dd c.orig ¾, 10 hari

15 mg/kg/d BID, max 800 mg/d, 8-30d Eg. BB 20 kg, 150 mg/x

R/ Dexamethasone 5 mg/mL 2 mL amp No. I S pro injeksi

30 mg/d kalau ada edema serebral atau vaskulitis

Strongyloidiasis R/ Albendazole 400 mg tab No. XIV S 2 dd tab I, habiskan

7 hari Trichuriasis R/ Albendazole 400 mg tab No. III

3 hari Enterobiasis R/ Albendazole 400 mg tab No. II

S 1 dd tab I, dosis kedua setelah 2 minggu Taeniasis R/ Praziquantel 600 mg tab No. I

S 1 dd tab I, sd

5-10 mg/kg sd Eg. BB 60 kg Schistosomiasis R/ Praziquantel 600 mg tab No. VI

S 3 dd tab II, habiskan

20 mg/kg/x 1 hari. Japonicum 3x/d, Hematobium, mansoni 2x/d. Eg. 60 kg Filariasis R/ Diethylcarbamazine 100 mg tab No. XXXVI

12 hari R/ Diethylcarbamazine 120 mg

Sach lactis qs

m.f. pulv. d.t.d. No. XXXVI S 3 dd pulv I, habiskan

6 mg/kg. Eg. BB 20 kg

Cutaneous larva migrans

R/ Albendazole 400 mg tab No. III S 1 dd tab I, habiskan

3-7 hari Rabies R/ Vaksin anti rabies vial No. IV

S pro injeksi

Deltoid (paha pada anak) 0,5 mL d0, d0, d7, d21 R/ Serum anti rabies 200 IU/mL vial No. I

S pro injeksi

20 IU/kg, ½ IM, ½ infiltrasi Avian influenza R/ Oseltamivir 75 mg cap No. X

Probable/confirm, 5 hari R/ Oseltamivir 75 mg cap No. VII

Profilaksis untuk suspek, 7 hari

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Anak

Kejang R/ Diazepam supp 5 mg No. I S pro intrarectal

Di rumah bisa 2x, di IGD 1x

<12 kg 5 mg, ≥12 kg 10 mg R/ Diazepam inj 5 mg/mL 2mL amp No. I

S pro infus

0,2-0,5 mg/kg, 2 mg/min, bisa diulang dalam 5 min max 10 mg

R/ Phenytoin inj 50 mg/mL 2mL amp No. I S pro infus

20 mg/kg in NS 50 cc, 20 min. Bisa + 5- 10 mg/kg. Rumat 5-10 mg/kg BID R/ Phenobarbital 50 mg/mL 1 mL amp No. I

S pro infus

20 mg/kg, 10-20 mg/mnt, max 1g. Bisa + 5-10 mg/kg. Rumat 3-5 mg/kg BID Rumatan KD R/ Valproic acid syr 250 mg/5mL 120mL fl No. I

S 3 dd c.orig I

R/ Valproic acid 250 mg tab No. XC S 3 dd tab I

Fokal, >15 mnt, deficit neuro hingga 1 th bebas kejang

15-40 mg/kg/d BID-TID, eg. 20kg Tab: 250 mg, 500 mg

Absans R/ Ethosuximide 250 mg/5mL fl No. I S 1 dd c.orig I

R/ Ethosuximide 250 mg cap No. XXX S 1 dd cap I

Awal 250 mg/d, naik 250mg/w, target 20 mg/kg/d, max 1,5g

Epilepsi R/ Valproic acid (lihat rumat kejang) Umum

R/ Carbamazepine 100mg/5mL 120mL fl No. I S 4 dd c.orig I

R/ Carbamazepine 200 mg tab No. LX S 4 dd tab ½

Fokal, 2ndary umum, eg 20kg

10-20 mg/kg/d QID, 6-12 th 4x50 mg,

>12 th 4x200 mg, 12-15 th max 1000 mg/d, >15 th max 1200 mg/d Omfalitis R/ Povidone iodine 2,5% fl No. I

S pro membersihkan tali pusat R/ Gentamicin salap 0,1% 5g tube No. I S 3 dd applic

Setelah dibersihkan dengan iodin R/ Cloxacillin 30 mg

Sach lactis qs

mf. pulv. d.t.d. No. XX S 4 dd pulv I, habiskan

Kalau toxic, 25-50 mg/kg/d QID, 5 hari Eg. BB 3kg (75-150 mg/d)

DM Tipe 1 Insulin 0,7-1 U/kg/d

Diare akut R/ Zinc syr 10 mg/5mL 100 mL fl No. I S 1 dd c.orig I

R/ Zinc 20 mg tab No. X S 1 dd tab I

<6 bulan 10 mg, >6 bulan 20 mg, 10 hari

Syr: 10mg/5mL 100 mL, 20mg/5mL 60 mL

R/ ORS for 200 mL sach No. III S 1 sach tiap habis diare

Tanpa dehidrasi: 5-10 cc/kg tiap diare Eg BB 20 kg

R/ ORS for 200 mL sach No. III S 1 sach tiap habis diare

Diare ringan sedang: 75 cc/kg dalam 3 h + tiap diare. Eg bb 20 kg

Diare berat <12 bulan: 30 cc/kg dalam 1 h, 70 cc/kg dalam 5h

Diare berat >12 bulan: 30 cc/kg dalam 0,5 h, 70 cc/kg dalam 2,5h

Campak R/ Vitamin A 200.000 IU cap No. III S 1 dd cap I hari 1, 2, dan 14

Sesuai usia, d1, d2. D14 kalau defisiensi vit A

Analgetik-antipiretik

Demam rematik akut R/ Penicillin G benzathine 1,2 juta U vial No. I S pro injeksi

0,6-1,2 juta U IM R/ Prednisone 5 mg tab no. LVI

S 4 dd tab II

60 mg/d OR 2 mg/kg/d QID, eg. 20 kg Karditis sedang 2-4w, berat 2-6w, taper off minggu terakhir lalu aspirin Neonatal sepsis

(WHO)

R/ Ampicillin inj 250 mg vial No. I S pro injeksi

W1: 2x50 mg/kg, W2-4: 3x50 mg/kg Eg. 3 kg. Vial: serb 250mg, 1g R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

W1 LBW: 1x3 mg/kg, W1 NBW: 1x5 mg/kg, W2-4: 1x7,5 mg/kg

(11)

R/ NaCl 0,9% 500 cc kolf No. I S pro infus

10 mL/kg in 30 min, 1-2x jika gangguan perfusi

Sindrom nefrotik R/ Prednisone 5 mg tab No. LXXXIV S 3 dd tab IV

60 mg/d OR 2 mg/kg/d TID, 4 w.

Lanjut 2/3 dosis, QD, alterate, 4-8w R/ Furosemide 40 mg tab No. VII

S 1 dd tab I

1-2 mg/kg/d, max 6 mg/kg/d R/ Spironolactone 25 mg tab No. VII

S 1 dd tab I

2-3 mg/kg/d R/ Albumin inj 20% 100 cc fl No. I

S pro infus

R/ Furosemide inj 10 mg/mL 2mL amp No. II S pro injeksi

1 g/kg selama 2-4 h. Edema refrakter, shock, alb <1

Lanjut furosemide 1-2 mg/kg IV Nefritis R/ Furosemide 40 mg tab No. VII

S 1 dd tab I

Bila edema berat R/ Amoxicillin syr 125mg/5mL 60mL fl No. I

S 3 dd c.orig ½, 7 hari

Hanya GNAPS. 50 mg/kg/d TID, 7-10 hari. Eg. 30 kg

R/ Prednisone 5 mg tab No. LXXXIV S 3 dd tab IV

60 mg/d OR 2 mg/kg/d TID R/ Captopril 12,5 tab No. XXI

S 3 dd tab I, ac

Bila HT tidak terkontrol dengan diuretic, 0,3-0,5 mg/kg/x, max 6 mg/kg/d

(12)

OBGY

Hiperemesis gravidarum I

R/ Dimenhydrinate 50 mg tab No. XXI S 3 dd tab I

R/ Vitamin B6 10 mg tab No. XXI S 3 dd tab I

Hiperemesis gravidarum II

R/ Metoclopramide 10 mg tab No. XXVIII S 4 dd tab I

Hiperemesis gravidarum III

R/ Metoclopramide 5mg/mL 2mL amp No. IV S pro injeksi

4x10 mg Abortus insipient /

inkomplit

R/ Methyl ergometrine 2mg/mL 1mL amp No. I S pro injeksi IM

UK <16 w: evakuasi R/ Oxytocin inj 10 IU/mL 1mL amp No. II

S pro infus

UK >16 w: tunggu spontan 20-40 IU dalam 1L kristaloid PEB dan eklamsia R/ MgSO4 40% 25 mL flc No. I

S pro injeksi

awal 4 g, rumat 6 g dalam 6 jam Hipertensi kehamilan R/ Nifedipine 20 mg tab No. XXVIII

S 4 dd tab I HT kronis, PE ringan,

profilaksis

R/ Calcium carbonate 500 mg tab No. XXI S 3 dd tab I

1,5-2 g/d R/ Acetyl salicylic acid 80 mg tab no. VII

S 1 dd tab I

1x75 mg Pematangan paru R/ Dexamethasone 5 mg/mL 2 mL amp No. I

S pro injeksi

6 mg tiap 12h selama 48h Tokolitik R/ Nifedipine 30 mg tab No. I

S 1 dd tab I

R/ Nifedipine 20 mg tab No. IV S 4 dd tab I

30 mg, lalu 10-20 mg tiap 4-6 h

Induksi persalinan R/ Oxytocin inj 10 IU/mL 1mL amp No. II S pro infus

20-40 IU dalam 1L kristaloid

PROM Induksi persalinan (lihat atas) Kalau gagal SC

PROM >18 jam Induksi persalinan (lihat atas) R/ Ampicillin inj 1g vial No. II S pro injeksi

2g IV tiap 6h hingga persalinan PPROM Pematangan paru (lihat atas)

R/ Ampicillin inj vial 1g No. II S pro injeksi

4x500 mg, 7 hari R/ Erythromycin 250 mg cap No. XXVIII

S 4 dd cap I

7 hari Korioamnionitis R/ Ampicillin inj 1g vial No. II

S pro injeksi

2g IV tiap 6h hingga persalinan R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

5 mg/kg tiap 24h R/ Metronidazole inj 5mg/mL 100 mL fl No. III

S pro injeksi

Kalau SC, 3x500 mg Atonia uteri R/ Oxytocin inj 10 IU/mL 1mL amp No. II

S pro infus

20-40 IU dalam 1L kristaloid R/ Tranexamic acid 100 mg/mL 5mL amp No. II

S pro injeksi

1g IV Endometritis R/ Ampicillin inj 1g vial No. II

S pro injeksi

2g IV in 60 min tiap 6h R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

1,5 mg/kg/x IV in 60 min tiap 8h R/ Metronidazole inj 5mg/mL 100 mL fl No. II

S pro injeksi

2x500

(13)

Mastitis R/ Cloxacillin 500 mg cap No. XL S 4 dd cap I

10-14 hari. Kompres hangat sebelum menyusui, kompres dingin setelah Tubo-ovarian

abscess

R/ Ampicillin inj 1g vial No. II S pro injeksi

2g IV in 60 min tiap 6h R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

1,5 mg/kg/x IV in 60 min tiap 8h R/ Clindamycin inj 15 mg/mL 4mL amp No. II

S pro injeksi

900 mg IV tiap 8 h in 30 min PID R/ Ceftriaxone inj 1g vial No. I

S pro injeksi

250 mg IM sd R/ Doxycycline 100 mg cap No. XXVIII

IV/PO, 14 hari R/ Metronidazole 500 mg tab No. XXVIII

14 hari. Bila curiga anaerob Abses bartholin R/ Doxycycline 100 mg cap No. XIV

Insisi drainase (+ kateter) OR marsupilisasi (sebelum abses atau setelah abses tenang)

Kista Gartner Eksisi atau insisi

Vaginitis atrofi R/ Estrogen 0,01% cream tube No. I S 2 dd applic

Bedah

Fraktur terbuka R/ Ceftriaxone inj 1g vial No. II S pro injeksi

Up to 24-72 h post debridement R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

Osteomyelitis R/ Vancomycin inj 500 mg vial No. IV S pro injeksi

2x1 g IV. MRSA R/ Clindamycin inj 15 mg/mL 4mL amp No. IV

S pro injeksi

4x600 mg IV. Anaerobes Apendisitis akut R/ Ceftriaxone inj 1g vial No. II

S pro injeksi

R/ Metronidazole 5mg/mL 100 mL fl No. I S pro injeksi

R/ Ketorolac inj 30mg/mL 1 mL amp No. I S pro injeksi

R/ Ondansetron inj 2mg/mL 2 mL amp No. I S pro injeksi, prn mual

Kolesistitis, kolangitis Antiemetik dan antipiretik R/ Ceftriaxone inj 1g vial No. II S pro injeksi

1x2g R/ Metronidazole 5mg/mL 100 mL fl No. IV

S pro injeksi

1g, lalu 3x500 mg

(14)

Minor

THT

OE sirkumskripta R/ Polymyxin B, Neomycin, Fludrocortisone acetate, lidocaine HCl ear drops fL No. I S 3 dd gtt II AD / AS, 5 hari

polymyxin B/neomycin/

fludrocortisone/lidocaine (10.000IU/5mg/1mg/40mg)/1cc R/ Acetic acid 2% 100 mL fL No. I

S 3 dd gtt IV AD / AS, 5 hari

OE difus R/ Kassa box No. I

S pro tampon

R/ Hydrocortisone 2,5% krim tube No. I S pro tampon

R/ Chloramphenicol 2% salap tube No. I S pro tampon

Kassa 4 x 3 cm, bagian 3 cm digulung padat hingga 1 cm, dioleskan

hydrocortisone 2.5% cream + chloramphenicol 2% ointment

R/ Amoxicillin 500 mg capl No. XXI S 3 dd capl I

Bila sistemik R/ Mefenamic acid 500 mg tab No. XXI

S 3 dd tab I prn nyeri

OMA oklusi R/ Ephedrine HCl 1% nasal drop fL No. I S 3 dd gtt II hidung kanan dan kiri

<12 th 0,5%

OMA hiperemis R/ Ephedrine HCl 1% nasal drop fL No. I S 3 dd gtt II hidung kanan dan kiri

<12 th 0,5%

R/ Amoxicillin 500 mg capl No. XXI S 3 dd capl I

Dewasa, 7 hari R/ Amoxicillin syr 125mg/5mL 60 ml fL No. II

S 3 dd c.orig I, 7 hari

Anak 25-50 mg/kg TID. Eg. BB 10 kg (250-500 mg/hari)

R/ Paracetamol syr 120 mg/5 mL 60 mL fL No. II S 3 dd c.orig I prn demam

10-15 mg/kg/x OMA Supurasi R/ Amoxicillin 500 mg capl No. XXI

S 3 dd capl I

Dewasa, 7 hari

Rujuk untuk miringotomi R/ Amoxicillin syr 125mg/5mL 60 ml fL No. II

S 3 dd c.orig I, 7 hari

Anak 25-50 mg/kg TID. Eg. BB 10 kg (250-500 mg/hari)

OMA Perforasi R/ H2O2 3% ear drop 100 mL fL No. I S 3 dd gtt X AD / AS

3x5-10 tetes, 3-5 hari (Hingga bersih) R/ Ofloxacin 3% ear drops fL No. I

S 2 dd gtt V AD/AS

2x5-10 tetes, max 2w

OMSK aman, tenang Rujuk timpanoplasty/miringoplasty

OMSK aman, aktif R/ H2O2 3% ear drop 100 mL fL No. I S 3 dd gtt X AD / AS

3x5-10 tetes, 3-5 hari (Hingga bersih) R/ Ofloxacin 3% ear drops fL No. I

S 2 dd gtt V AD/AS

2x5-10 tetes, max 2w Mirigitis bulosa R/ Amoxicillin 500 mg capl No. XXI

S 3 dd capl I

7d, karena sulit bedain viral dan bakteri

R/ Amoxicillin syr 125mg/5mL 60 mL fL No. IV S 3 dd c.orig II

Anak BB: 20 kg 800 mg/hari 250 mg/x; 30 mL/hari 210 mL

R/ Asam mefenamat 500 mg tab No. XXI S 3 dd tab I prn nyeri

Rujuk: curiga rupture, komplikasi R/ Ibuprofen syr 100mg/5mL 60 mL fL No. II

S 4 dd c.orig I prn nyeri

20mg/kgBB/hari TID-QID BB 20 kg 400mg/hari

BPPV Lihat neuro

Meniere Diuretic kombinasi HCT (belum terbukti) Low salt diet, smoking cessation.

Rujuk

Mabuk perjalanan Scopolamin Antikolinergik u/ prefensi dan akut

R/ Dimenhydrinate 50 mg tab No. XXVIII S 4 dd tab I

Antihistamin sedative kerja panjang untuk prevensi. Max 400 mg/d

(15)

Labirintitis Antibiotic Removal of infected tissue, rehab

Vestibular neuritis Brief high dose steroid Rehab

Perikondritis R/ Ciprofloxacin 500 mg tab No. XIV S 2 dd tab I, habiskan

Supuratif: insisi, nekrosis: eksisi 2x500-750 mg, 1w

Infeksi fistula preaurikular

R/ Erythromycin 500 mg tab No. XXVIII S 4 dd tab I, habiskan

7 hari, kalau ada abses insisi R/ Erythromycin syr 200mg/5mL 60 mL fL No. III

S 4 dd c.orig I

30-50 mg/kg/d

Eg. BB 20 kg (600-1000 mg/d) Antipiretik

Serumen prop R/ Karbogliserin 10% ear drops fL No. I S 3 dd gtt IV

3 hari, selama 5 menit

Rhinosinusitis akut bacterial

R/ Coamoxiclav 625 tab No. XXX S 3 dd tab I, habiskan

10 hari R/ Coamoxiclav syr (125/31,25mg)/5mL fl No. I

Anak: 40 mg/kg/d TID (amox) Eg. BB 20 kg

R/ Mometasone furoate 50 µg/spray fl No. I S 1 dd puff II

Kortikosteroid topikal Rhinosinusitis akut viral R/ Mometasone furoate 50 µg/spray fl No. I

S 1 dd puff II

Post-viral R/ Ephedrine HCl 1% nasal drop fL No. I

S 3 dd gtt II hidung kanan dan kiri, 3 hari

<12 th 0,5%

R/ Cetirizine 10 mg tab No. VII S 1 dd tab I

Antihistamin oral bila perlu R/ Ambroxol 30 mg tab No. XXI

S 3 dd tab I

Mukolitik bila perlu. Bisa tambah analgetik

Rhinosinusitis kronik R/ Mometasone furoate 50 µg/spray fl No. I S 1 dd puff II

Kortikosteroid topikal Rhinitis alergi R/ Cetirizine 10 mg tab No. VII

S 1 dd tab I

Persisten berat tambah ini Rhinitis vasomotor/

autonomik

Golongan bersin, tersumbat R/ Ipratoprium bromide 0,03% nasal spray No. I

S 2 dd puff II

Golongan rinore R/ Cetirizine 10 mg tab No. VII

S 1 dd tab I Rhinitis

medikamentosa

Dengan irigasi hidung R/ Prednisone 5 mg tab No. LXXXIV

S 3 dd tab IV

Steroid oral dosis tinggi 5-10 hari, taper off

Rhinitis atrofi R/ Doxycycline 100 mg cap No. XIV S 2 dd cap I

Ab spektrum luas/sesuai resistensi.

Dengan cuci hidung 2x/d

Faringitis bacterial R/ Amoxicillin 500 mg capl No. XXX S 3 dd capl I

6-10 hari R/ Amoxicillin syr 125mg/5mL 60 ml fL No. V

Anak: 50 mg/kg TID, 10 hari Eg. BB 15 kg (750 mg/d) R/ Dexamethasone 0,5 mg tab No. IX

S 3 dd tab I

3 hari R/ Dexamethasone 0,05 mg

Sach. lactis qs mf. pulv. d.t.d. No. IX S 3 dd pulv I

Anak: 0,01 mg/kg/d TID, 3 hari Eg. BB 15 kg (0,15 mg/d)

(16)

Faringitis viral R/ Dextromethorphan HBr 15 mg tab No. XVIII S 3 dd tab II, prn batuk

Kalau batuk kering R/ Ambroxol 30 mg tab No. IX

S 3 dd tab I, prn batuk

Kalau batuk berdahak Laringitis R/ Coamoxiclav 625 mg tab No. XXI

R/ Dexamethasone 0,5 mg tab No. IX S 3 dd tab I

Bisa tambah antipiretik/analgetik Tonsilitis (difteri lihat

IPD)

Paracetamol/ibuprofen

R/ Dexamethasone 0,5 mg tab No. IX S 3 dd tab I

R/ Amoxicillin 500 mg capl No. XXX S 3 dd capl I

Kalau bakteri, 6-10 hari R/ Amoxicillin syr 125mg/5mL 60 ml fL No. V

Kalau bakteri, anak: 50 mg/kg TID, 10 hari. Eg. BB 15 kg (750 mg/d)

Abses peritonsilar R/ Coamoxiclav 625 mg tab No. XXI S 3 dd tab I, habiskan

7-10 hari. Insisi drainase. Tambah analgetik

Croup R/ Dexamethasone 4 mg tab No. III S 1 dd tab 2 ½ sd

0,6 mg/kg/d, max 10 mg, sd IV/IM/PO

Epinephrine nebulisasi Moderate-severe resp distress

Paracetamol/ibuprofen Trakeitis bacterial R/ Ceftriaxone inj 1g vial No. I

S pro injeksi

50 mg/kg IM OR 1x1-2 g

(17)

Mata

Konjungtivitis viral R/ Carboxymethylcellulose eye drop strip No. I S 6 dd gtt OD / OS

Artificial tear Konjungtivitis

klamidia

R/ Doxycycline 100 mg cap No. XLII S 2 dd cap I, habiskan

21 hari Konjungtivitis

bakterial

R/ Chloramphenicol 0,5% ED fl No. I S 4 dd gtt I OD/OS

Konjungtivitis vernal R/ Sodium chromolyn 2% ED fl No. I S 2 dd gtt I ODS

Keratitis HSV R/ Acyclovir 3% EO tube No. I S 5 dd applic OD/OS

Neonatus: IV antivirus Keratitis Zoster R/ Acyclovir 400 mg tab No. L

S 5 dd tab II

7-10 hari R/ Fluorometholone 0,1% ED fl No. I

S 3 dd gtt I OD/OS

Boleh ditambahkan Keratitis bacterial R/ Chloramphenicol 0,5% ED fl No. I

S 4 dd gtt I OD/OS

Keratitis sicca R/ Carboxymethylcellulose eye drop strip No. I S 6 dd gtt OD / OS

Rujuk Keratitis amoeba R/ Polyhexamethylene biguanide 0,02% ED No. I

S UC

q1h all day 2 hari, q1h waking hours 1w, q6h hingga sembuh

Keratitis fungal R/ Natamycin 5% ED fl No. I S UC

q2h 3 hari, q4h hingga sembuh (14-21 hari)

Episkleritis R/ Sodium diclofenac ED strip No. I S 6 dd gtt I OD/OS

Pinguekulitis R/ Fluorometholone 0,1% ED fl No. I S 3 dd gtt I OD/OS

Rujuk untuk eksisi Ptegirium R/ Carboxymethylcellulose eye drop strip No. I

S 6 dd gtt OD / OS

R/ Sodium diclofenac ED strip No. I S 6 dd gtt I OD/OS

Dakrioadenitis R/ Paracetamol 500 mg tab No. XV S 3 dd tab I, prn nyeri

Kompres hangat Dakriosistitis R/ Coamoxiclav 625 mg tab No. XXX

10-14 hari. Kompres hangat, masase, bisa tambah analgetik

Hordeolum R/ Chloramphenicol 0,5% ED fl No. I S 3 dd gtt I OD/OS

Utama: kompres hangat 4-6x/d 15 min, bersihkan kelopak

Blefaritis anterior R/ Chloramphenicol 0,5% ED fl No. I S 3 dd gtt I OD/OS

Kompres hangat, bersihkan dgn air + baby shampoo, masase

Xerophthalmia R/ Vitamin A 100.000 IU cap No. III S 1 dd cap I hari 1, 2, 15

sesuai usia

XN, XIA d1. XIB ke atas d1, d2, d15 Hifema R/ Tranexamic acid 500 mg tab No. VI

S 3 dd tab I

Tirah baring 30^o, PCT R/ Acetazolamide 250 mg tab No. V

S 2 tab loading, lanjut 4 dd tab 1

5A: acetaminophen, acetazolamide, atropine, anti-inflam, asam tranex R/ Atropine sulfate 1% ED fl No. I

S 1 dd gtt I OD/OS

R/ Fluorometholone 0,1% ED fl No. I S 3 dd gtt I OD/OS

Glaukoma akut R/ Acetazolamide 250 mg tab No. V S 2 tab loading, lanjut 4 dd tab 1

Carbonic anhydrase inh: aqueous humor inflow

R/ Timolol 0,5% ED fl No. I S 2 dd gtt I OD/OS

β-blocker: aqueous humor inflow R/ Fluorometholone 0,1% ED fl No. I

S 3 dd gtt I OD/OS

Corticosteroid

(18)

Kulit

MH dewasa R/ FDC PB/MB dewasa No. I

S hari 1: rifampisin 1 dd cap II, dapson 1 dd tab I, (clofazimine 1 dd cap III); hari 2-28:

dapson 1 dd tab I, (clofazimine 1 dd cap I)

PB: 6-9 bulan

Rifampicin 600/mo, Dapson 100 mg/d MB: 12-18 bulan

Rifampicin 600/mo, Dapson 100 mg/d, Clofazimine 300 mg/mo, 50 mg/d

Kalau MB R/ Rifampicin 600 mg tab No. I

S 1 dd tab I, hari pertama R/ DDS tab 100 mg No. XXVIII S 1 dd tab I, hari 1-28

R/ Clofazimine 100 mg cap No. III S 1 dd cap III, hari pertama R/ Clofazimine 50 mg cap No. XXVII S 1 dd cap I, hari 2-28

MH anak R/ FDC PB/MB dewasa No. I

S hari 1: rifampisin 1 dd cap II, dapson 1 dd tab I, (clofazimine 1 dd cap III); hari 2-28:

dapson 1 dd tab I, (clofazimine 1 qad cap I)

PB: 6-9 bulan

Rifampicin 450mg/mo, Dapson 50 mg/d MB: 12-18 bulan

Rifampicin 600/mo, Dapson 100 mg/d, Clofazimine 150 mg/mo, 50 mg/2d

<10 th:

Rifampicin 300 mg/mo, Dapson 25 mg/d, Clofazimine 50 mg 2x/w Kalau MB

R/ Rifampicin 300 mg cap No. I S 1 dd cap I, hari pertama R/ Rifampicin 150 mg cap No. I S 1 dd cap I, hari pertama R/ DDS tab 50 mg No. XXVIII S 1 dd tab I, hari 1-28

R/ Clofazimine 50 mg cap No. XVI

S hari 1: 1 dd cap III, hari 2-28: 1 qad cap I MH tipe PB lesi

tunggal

R/ Rifampicin 600 mg tab No. I S 1 dd tab I sd

R/ Ofloxacin 400 mg tab No. I S 1 dd tab I sd

R/ Minocycline 100 cap No. I S 1 dd cap I sd

Scabies R/ Permethrin 5% cream tube No. I

S applic setelah mandi seluruh tubuh kecuali lubang dan kepala, diamkan 8-12 jam, bilas

8-12 jam, CI <2 bulan

R/ Precipitated sulfur 5% pot No. I

S applic setelah mandi seluruh tubuh kecuali kepala 3 hari berturut-turut

3x24 jam

Pedikulosis kapitis R/ Permethrin 1% lotion fl No. I S applic 10 min-2 h, bilas Pedikulosis pubis R/ Permethrin 1% lotion fl No. I

S applic 10 min-2 h, bilas

1^st line Tinea facialis, kruris,

corporis

R/ Ketoconazole 2% cream tube No. I S 2 dd applic part dol

Hingga 1-2 mgg sembuh R/ Griseofulvin 500 mg tab No. XXVIII

S 1 dd tab II

2-4w. 0,5-1 g OR 10-25 mg/kg/d QD/BID, anak 0,25-0,5 g

Tinea pedis/manus Antijamur topikal

R/ Itraconazole 100 mg cap No. XXVIII S 1 dd cap II, habiskan

Anak 5 mg/kg/d. 2w Tinea unguium R/ Itraconazole 100 mg cap No. CXII

S 2 dd cap II dosis denyut

2 denyut tangan, 3-4 kaki. 2x200 1w, 3w off. Anak 5 mg/kg/d 2-3 mo Tinea kapitis R/ Griseofulvin 500 mg tab No. CXII

S 1 dd tab II

8-12w. 0,5-1 g OR 10-25 mg/kg/d QD/BID, anak 0,25-0,5 g

PV R/ Ketoconazole 2% shampoo fl No. I

S 1 dd applic part dol, diamkan 5 menit, bilas

3 hari R/ Itraconazole 100 mg cap No. XIV

S 1 dd cap II, habiskan

Lesi ekstensif, tidak membaik dengan topikal, rekuren sering. 7 hari

(19)

Kandidosis kutan R/ Ketoconazole 2% cream tube No. I S 2 dd applic part dol

R/ Itraconazole 100 mg cap No. XIV S 1 dd cap I, habiskan

7-14 hari Pyoderma R/ Potassium permanganate sol 1:5000 fl No. I

S pro kompres terbuka

3x/hari, bila lesi basah/krusta R/ Fusidic acid 2% krim tube No. I

S 3 dd applic part dol

7-10 hari R/ Cloxacillin 500 mg cap No. XX

4x250-500 mg OR 25-50 mg/kg/d QID Kalau lesi luas, 5-7 hari

Dermatitis perioral R/ Metronidazole 0,75% krim tube No. I S 2 dd applic part dol, 8 minggu R/ Doxycycline 100 mg cap No. XXI S 1 dd cap I, habiskan

3 minggu Hidradenitis

supurativa dengan abses

R/ Clindamycin 300 mg cap No. VIII S 2 dd cap I

R/ Rifampicin 300 mg cap No. VIII S 2 dd cap I

4-12 w, klo ga ada abses seperti pyoderma biasa

Eritrasma R/ Erythromycin 250 mg cap No. LVI S 4 dd cap I, habiskan

2-3 w. Corynebacterium minitussismum (eritroskuamosa di lipatan)

Ektima R/ Cloxacillin 500 mg cap No. XX S 4 dd cap I, habiskan

GABHS (ulkus punched out, krusta berlapis)

Varicella R/ Acyclovir 400 mg tab No. LXX S 5 dd tab II

5-7 hari. <12 th 4x10-20 mg/kg, R/ Chlorpheniramine maleate 4 mg tab No. XXI

S 3 dd tab I

Hindari antipiretik Herpes zoster R/ Acyclovir 400 mg tab No. LXX

S 5 dd tab II

7-10 hari. <12 th 4x20 mg/kg max 3,2 g/d

R/ Prednisone 5 mg tab No. LXXXIV S 3 dd tab IV

7 hari, Otikus PNPH R/ Gabapentin 100 mg cap No. XXI

S 3 dd cap I

Veruca vulgaris R/ Salicylic acid 40% pot No. I S 2 dd applic part dol

Diamkan seharian, kurang lebih 12 minggu

Moluscum contagiosum

R/ Trichloroacetic acid 25% fl No. I S IMM

Enukleasi, bisa self limiting Aphtous ulcer R/ Triamcinolone oral base gel tube No. I

S 2 dd applic part dol R/ Vitamin C 50 mg tab No. XII S 3 dd tab I

Dermatitis kontak Steroid topikal potensi sedang*

R/ Loratadine 10 mg tab No. VII S 1 dd tab I

Simtomatik, max 2 minggu R/ Vaseline album 30 g pot No. I

Pelembab R/ Prednisone 5 mg tab No. XII

S 2 dd tab II

20 mg/d 3 hari QD-TID. Kondisi berat Dermatitis atopic Steroid topikal *

R/ Cetirizine syr 5mg/5mL 60 mL fl No. I S 1 dd c.orig I

< 6 th 2,5-5 mg/d R/ Vaseline album 30 g pot No. I

S 2 dd applic part dol Napkin eczema R/ Zinc oxide salap tube No. I

S 2 dd applic part dol, 1 minggu

(20)

Dermatitis seboroik R/ Ketoconazole 2% shampoo fl No. I

S 1 dd applic part dol, diamkan 5 menit, bilas

2-3x/w, kepala

Steroid topikal potensi sedang max 2 minggu* Potensi kuat bila berat, lemah bila bayi R/ Ketoconazole 2% cream tube No. I

Curiga infeksi P. ovale R/ Cetirizine 10 mg tab No. VII

S 1 dd tab I

Max 2 minggu R/ Prednisone 5 mg tab No. XII

S 2 dd tab II

20-30 mg/d. Kasus berat Neurodermatitis Steroid topikal potensi kuat*

R/ Vaseline album 30 g pot No. I S 2 dd applic part dol

R/ Chlorpheniramine maleate 4 mg tab No. XXI S 3 dd tab I

Pitiriasis rosea R/ Salycylic acid 1% talc fl No. I S 2 dd applic part dol FDE R/ Cetirizine 10 mg tab No. VII

S 1 dd tab I Steroid topikal*

List kortikosteroid yang sering*

Potensi Obat-konsentrasi-sediaan Pemakaian/hari

Sangat kuat (class 1) Clobetasol proprionate 0,05% cream/ointment Betamethasone dipropionate 0,05% ointment

2x 1-2x Kuat (class 2-3) Betamethasone dipropionate 0,05% cream

Mometasone furoate 0,1% ointment Triamcinolone acetonide 0,1% ointment

1-2x 1x 2-3x Sedang (class 4-5) Mometasone furoate 0,1% cream

Triamcinolone acetonide 0,1% cream

1x 2-3x

Lemah (class 6-7) Hydrocortisone 1%/2,5% cream 2-4x

(21)

Kelamin

Sifilis R/ Penicillin G Benzathine 1,2 juta IU vial No. II S pro injeksi

Primer, 2ndary, laten tes –: 2,4 jt sd Laten tanpa tes, laten >1 th 3w R/ Doxycycline 100 mg cap No. LX

Alergi penicillin, 30 hari Ulkus molle

(chancroid)

R/ Erythromycin 500 mg tab No. XXVIII S 4 dd tab I, habiskan

7 hari (cause: H. ducreyi) Limfogranuloma

venereum

R/ Erythromycin 500 mg tab No. LVI S 4 dd tab I, habiskan

14 hari (cause: C. trachomatis) Herpes genital R/ Acyclovir 400 mg tab No. XXI

S 3 dd tab 1

Episode pertama, 7 hari R/ Acyclovir 400 mg tab No. XV

S 3 dd tab 1

Rekuren, 5 hari Condyloma

acuminatum

R/ Podophyllin tincture 25% fl No. I S IMM

Pakaikan Vaseline album disekitar, lalu totol podofilin di kondiloma

R/ Trichloroacetic acid 50% fl No. I S IMM

Terapi kimia yang boleh ibu hamil

GO R/ Cefixime 100 mg cap No. IV

S 1 dd cap IV sd

Chlamydia R/ Azithromycin 500 mg tab No. II S 1 dd tab II, sd

Kandidosis vulvovaginitis

R/ Clotrimazole ovule 500 mg No. I S 1 dd ovule I

Intravagina R/ Itraconazole 100 mg cap No. II

S 1 dd tab II dosis tunggal

Sistemik Trikomoniasis R/ Metronidazole tab 500 mg No. IV

S 1 dd tab IV sd

BV R/ Metronidazole tab 500 mg No. IV

S 1 dd tab IV sd

(22)

Neurologi

Absance / petit mal R/ Ethosuximide cap 250 mg no. VI S 1 dd cap II

Increase per 250 mg, max 1,5 g. Anak start 1x250 mg

Epilepsi general R/ Valproic acid 250 mg tab No. XIV S 2 dd tab I

15 mg/kg/d, 2-3x. Max 50 mg/kg/d R/ Valproic acid syr 250mg/5mL 60 mL fL No. I

S 3 dd c.orig ½

Eg. BB 20 kg 300 mg/day Epilepsi fokal R/ Carbamazepine 200 mg tab

S 1 dd tab I

10-20 mg/kg/d OR 100-200 mg QD-BID.

Increase per 200 mg max 2 g Meningitis

bakterialis (Medscape)

R/ Ampicillin inj 1g vial No. I S pro injeksi

Empiris <1 mo, 10-14 hari Ampicillin 4x100 mg/kg IV Gentamicin 3x2,5 mg/kg IV R/ Gentamicin inj 40 mg/mL 2mL amp No. I

S pro injeksi

R/ Vancomycin inj 500 mg vial No. I S pro injeksi

Empiris >1 mo

Vancomycin 4x15 mg/kg IV Ceftriaxone 1-2x75-100 mg/kg IV R/ Ceftriaxone inj 1g vial No. I

S pro injeksi

R/ Vancomycin inj 500 mg vial No. I S pro injeksi

Empiris Dewasa

Vancomycin: 3x15 mg/kg IV Ceftriaxone: 2x2 g IV

>50 th ampicillin: 6x2g R/ Ceftriaxone inj 1g vial No. I

S pro injeksi

R/ Ampicillin inj 1g vial No. I S pro injeksi

R/ Dexamethasone 5mg/mL 2 mL amp No. I S pro injeksi

0,6 mg/kg/d QID, 4 hari Ensefalitis viral R/ Acyclovir inj 250 mg vial No. I

S pro injeksi

Ensefalitis HSV: 3x10 mg/kg in 100cc NS 1h, 10-14 hari

Neonatus: 3x20 mg/kg, 14-21 hari R/ Mannitol 20% 500 cc kolf No. I

S pro infus

Menurunkan TIK: 0,5-1 g/kg/x 20% = 20g/100mL

R/ Methylprednisolone inj 125 mg vial No. I S pro injeksi

Neuritis optic, myelitis, vasculitis, ADEM 15 mg/kg/d QID, 3-5 hari, lanjut

Prednisone 1-2 mg/kg/d, 7-10 hari Stroke iskemik R/ Alteplase inj 50 mg vial No. I

S pro injeksi

0,9 mg/kg IV, max 90 mg. 10% bolus in 1 min, sisa infus in 60 min

R/ Aspirin 80 mg tab No. IV S 1 dd tab IV

Aspirin 325 mg R/ Clopidogrel 75 mg tab No. IV

S 1 dd tab IV

Clopidogrel 300 mg Stroke hemoragik R/ Nicardipine inj 1 mg/mL 10mL amp No. I

S pro infus

5-15 mg/h IV infusion R/ Mannitol 20% 500 cc kolf No. I

S pro infus

0,5-1 g/kg IV. Dapat diulang 4-6 jam R/ Nimodipine 30 mg tab No. LXXXIV

S 6 dd tab II

21 hari. Antivasospasm Subarachnoid

hemorrhage

R/ KCl 7,46% 25 mL flc No. I S pro infus

IV NS with 20 mmol KCl/L, 125-150 ml/h

R/ Nimodipine 30 mg tab No. LXXXIV S 6 dd tab II

21 hari. Prevent delayed ischemia R/ Levetiracetam 500 mg tab No. XIV

S 2 dd tab I

7 hari. Prevent seizure Trauma medulla

spinalis

R/ Methylprednisolone inj 125g vial No. XII S pro injeksi

Hanya bila <8h onset. 30 mg/kg in 15 min, lanjut 5,4 mg/kg/h sampai 23 h.

Up to 48 h kalo mulai >3h onset BPPV R/ Betahistine mesylate 6 mg tab No. XXI 3x6-12 mg

(23)

S 3 dd tab I

Migraine R/ Ibuprofen 400 mg tab No. XXI S 3 dd tab I

Non-specific abortive R/ Sumatriptan 50 mg capl No. II

S ½ capl tiap 2 jam, prn nyeri

Specific abortive

Sumatriptan 25-100 mg tiap 2 jam max 200

Ergotamine 1-2 mg tiap jam, max 3x R/ Ergotamine 2 mg tab No. III

S 1 tablet tiap jam, prn nyeri R/ Flunarizine 5 mg tab No. XXVIII S 2 dd tab I

Prophylaxis, bisa juga amitriptilin (lihat migraine) dan propranolol 1x10 R/ Metoklopramid 10 mg tab No. X

S 2 dd tab I, prn mual

Bila mual Tension type

headache

R/ Ibuprofen 400 mg tab No. XXI S 3 dd tab I prn nyeri

R/ Amitriptylline 25 mg tab No. VII S 1 dd tab I sebelum tidur

Prophylaxis Trigeminal neuralgia R/ Carbamazepine 200 mg tab No. VII

S 2 dd tab ½

Maintenance 400-1200 mg/d BID

Cluster headache Oxygen 7-10 LPM Abortif

R/ Amitriptylline 25 mg tab No. VII S 1 dd tab I sebelum tidur

Profilaksis. Bisa verapamil 3x80-160 mg

LBP R/ Ibuprofen 400 mg tab No. XXI

S 3 dd tab I

Klo ga mempan relaksan, opioid, bedah Neuropati R/ Pregabalin 75 mg cap No. XIV

S 2 dd cap I

Target 300-600 mg/d Bell’s palsy R/ Prednisone 5 mg tab No. LXXXIV

S 3 dd tab IV

1 mg/kg/d OR 60 mg/d, TID, 7 hari Taper off setelah itu

R/ Carboxymethylcellulose eye drop strip No. I S 6 dd gtt OD / OS

Dan plaster mata malam R/ Mecobalamine 500 mg tab No. XXI

S 3 dd tab I

Myasthenia gravis R/ Pyridostigmine 60 mg tab No. XX S 4 dd tab I

4x60-120 mg

GBS IVIg 0,4 g/kg/d, 5 hari Or plasmapheresis

Hipokalemia R/ Potassium chloride 600 mg tab No. VI S 3 dd tab I

KSR Parkinson R/ Levodopa/Benserazide tab No. VII

S 3 dd tab ½

100/25 mg Alzheimer R/ Donepezil 5 mg tab No. VII

S 1 dd tab I, sebelum tidur

Acetylcholinesterase inhibitor R/ Memantine 5 mg tab No. VII

S 1 dd tab I

NMDA-receptor antagonist

(24)

Psikiatri

Intoksikasi alkohol R/ Fomepizole inj 1g/mL vial No. I S pro injeksi

15 mg/kg in 30 min, 10 mg/kg tiap 12 h, Hingga 5 dosis/serum alc <20 mg/dL R/ Folinic acid inj 100 mg vial No. I

S pro injeksi

Suspek methanol, 1 mg/kg, max 50 mg R/ Thiamine inj 250mg/mL 1 mL amp No. II

S pro injeksi

Suspek ethylene glycol: 4x100 mg IV R/ Pyridoxine inj 100mg/mL 1 mL amp No. II

S pro injeksi

Suspek ethylene glycol: 4x50 mg IV Withdrawal alkohol R/ Chlordiazepoxide 25 mg cap No. XX

S 4 dd cap I

Kurangi 20% tiap 5-7 hari R/ Vitamin B1 50 mg tab No. XL

S 4 dd tab II

R/ Vitamin B9 1 mg tab No. XX S 4 dd tab I

Intoksikasi opioid R/ Naloxone 0,4mg/mL 2mL amp No. II S pro injeksi

0,4-2 mg IM/SC, ulang tiap 2-3 min Max 10 mg

Withdrawal opioid Sediaan 50 mg/5mL 1x20-30 mg, titrasi 5-10 mg. Target 80-120 mg

Intoksikasi benzo R/ Flumazenil inj 0,1mg/mL 5mL vial No. I S pro injeksi

0,2 mg IV bolus, ulang 0,3 mg 30 s, lalu 0,5 mg 1 min, max 3 mg/h

Skizofrenia, gangg.

waham menetap

R/ Risperidone 2 mg tab No. X S 2 dd tab I

Max 8 mg/d EPS R/ Trihexyphenidyl tab 2 mg No. XIV

S 2 dd tab I Sindroma

neuroleptic maligna

R/ Diazepam inj 5 mg/mL 2mL amp No. I S pro injeksi

10 mg IV tiap 8h Gaduh gelisah R/ Haloperidol HCl 5 mg/mL ampul No. II

S pro injeksi

5 mg IM ulang tiap 30 menit. Max 20 mg/d

Gangg. bipolar ep manik

R/ Asam valproate 250 mg tab No. XIV S 2 dd tab I

20 mg/kg/d OR 500-750 mg/d

OR lithium carbonate 2-3x300-600 mg Gangg. bipolar ep

depresi

R/ Asam valproate 250 mg tab No. XIV S 2 dd tab I

20 mg/kg/d OR 500-750 mg/d R/ Fluoxetine 20 mg cap No. VII

S 1 dd cap I pagi hari

Gangg. depresi R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

Gangg. panik R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

Hingga 1 tahun bebas R/ Alprazolam 0.5 mg tab No. VII

S 1 dd tab I sebelum tidur

4-6 minggu, taper off

GCM R/ Clobazam 10 mg tab No. VII

S 2 dd tab ½

Benzodiazepine 2-4 minggu, bisa tambah buspirone

R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

Gangg. Penyesuaian R/ Clobazam 10 mg tab No. VII S 2 dd tab ½

R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

PTSD R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

Fobia R/ Fluoxetine 20 mg cap No. VII S 1 dd cap I pagi hari

Exposure therapy, flooding

OCD R/ Fluoxetine 20 mg cap No. VII

(25)

Insomnia R/ Lorazepam 1 mg tab No. VII S 1 dd tab I, sebelum tidur

Hypersomnia R/ Methylphenidate 10 mg tab No. V S 2 dd tab ½

10-60 mg/d. Stimulant: siang hari Parafilia R/ Fluoxetine 20 mg cap No. VII

CBT Disfungsi ereksi R/ Fluoxetine 20 mg cap No. VII

S 1 dd cap I pagi hari ADHD, retardasi

mental

R/ Methylphenidate 10 mg tab No. V S 2 dd tab ½

Max 60 mg/d

EA

Syok anafilaktik R/ Epinephrine inj 1:1000 1mL amp No. I S pro injeksi IM

0,5 µg IM >12 th, 0,3 µg IM 6-12 th, 0,15 µg IM <6 th

R/ Diphenhydramine 10mg/mL 1mL amp No. V S pro injeksi IM

1mg/kg IM max 50 mg R/ Hydrocortisone 100 mg vial No. I

S pro injeksi IM

10 mg IM >12 th, 5 mg IM 6-12 th, 2,5 mg IM 6 bl-6 th, 250 µg/kg IM <6 bl Angioedema R/ Epinephrine inj 1:1000 1mL amp No. I

S pro injeksi

Gangguan napas. 0,3 mL SC/IM, ulang 10 min

Bila gejala menetap 2w dosis 2-4 kali lipat

Syok sepsis R/ Norepinephrine 1 mg/mL 4mL amp No. I S pro infus

0,1-0,5 µg/kg/min R/ Meropenem inj 500 mg vial No. I

S pro injeksi

3x500, max 2g/d Syok kardiogenik R/ Dopamine 40 mg/mL 5mL amp No. I

S pro infus

SBP<100, shock, 5-10 µg/kg/min R/ Dobutamine 50 mg/mL 5mL amp No. I

S pro infus

SBP 70-100, no shock, 0,5-20 µg/kg/min

R/ Norepinephrine 1 mg/mL 4mL amp No. I S pro infus

SBP <70, 0,1-0,5 µg/kg/min Keracunan

organofosfat

Bilas lambung Kalau sadar

R/ Atropine sulfate 0,25 mg/mL 1mL amp No. VI S pro injeksi

2 mg bolus, tiap 30 min 0,5 mg hingga tidak ada gejala

Keracunan arsen Besi sulfat Untuk bilas lambung

Keracunan sianida Tiosulfat