NGHIEN CUU MOT SO DAC DIEM LIEN QUAN CHAN DOAN DENH MONG THjT QT MAT
TOM T A T
Miic tieu: Tim hiiu mdt sd ddc diem lidn quan chin dodn b$nh mdng thit & mit Ddi twgng vd phuvng phdp nghidn cwu: Nghiin edy dwac tiin hdnh theo phwang phdp md td cit ngang vdi 91 mdng thit d mit Kit qua:
T^ li cdc loai dd mdng Id twang dwang khi so sdnh v&i nhau vd nhw nhau giwa nam vd nir.
Vi tri mdng Id khdng phdn biet. Mgng mit phai (27,0%), mdng mit trdi (33,3%) vd mdng 2 mit (39,7%).
Da sd mdng gdc trong (90,9%), chi cd 9,1% Id mdng kdp. Sw khdc biet cd y nghTa thdng ke (p<0.001).
Mdng chu yiu gdp & hinh thdi mdng xa (87.9%), chicd 12,1% Id mdng mdu (p<0,Q01).
Ty Id mit cd bdnh phdi hap twang doi l&n (chiim 79,5%).
Tw khda: Mdng thit SUMMARY
Background: To find out some elements related diagnosed with pterygium. Patients: 63 patients diagnosed pterygium and treated at of ophthalmologic of 103 Hospital and Institute of Aviation Medicine 7/2008 to 4/2009 (resident In hospital). Method:Cross - Obsen/ation study. Conclusion:
The rate of the degrees (I, II, III, IV) of pterygium simitar when compared to each other and pterygium encounter rate In men just as the pterygium encounter rate in women.
The rate of pterygium with the locations (right eye or left eye or both eyes) is not different Pterygium in hght eye (27.0%), pterygium in left eye (33.3%) and pterygium in both eyes - bilateral pterygium (39.7%).
Pterygium in the inner comer of the eye (in the palpebral fissure of nasal side) is the majority (90,9%). only 9.1% were double pterygium. The difference was statistically significant (p <0.001).
Pterygium primarily seen in fibrous morphology- fibrovascular conjunctival (87.9%). only 9.1% were vascular pterygium.
Percentage of eyes with the combination of various diseases with pterygium is relatively large.
Keywords: Pterygium (conjunctiva).
Dfij VAN e e
Mflng thit Id mflt b|nh p h i bien trong nhan khoa.
Id mflt trong nhij-ng nguy&n nhdn quan trpng gdy giam thj lac va mii Ida [1,5,8].
Mflng tir liic hinh thanh vd t i l n tnen ed the k l o ddi hdng ehuc ndm, eOng cd the phdt t r i l n nhanh trong mflt vdi ndm th^m chi trong vai thang. Mdng tien t r i l n ed the gdy kich thich chay nade m i t , do mat, giam thj lac do ehe l i p tryc quang hoe, eo kdo giae mac gdy
LE DINH ANH - Benh vi^n 103 LE DifC HANH - B^nh vi^n Trung uxmg Qudn d^i 10S loan thj, hgn c h i vdn nhdn do dinh mi du...[5,6,7,8].
Nh&ng b^nh p h i i hop tr&n m i t mflng thjt c6 llSn quan mat thilt vdi vi^e d i l u tri mflng thit Phlu thuylt d t mflng ghdp k i t mge ria t a thdn hi$n dang Id phaong phdp d i l u tn pho b i l n . NhO'ng b^nh nhdn mflng kdp, cgn eung do ho^c b&nh nhdn cd tiln SLP p h l u thuat tgi vimg ria nhy m l c l t be ciing gidc mac, m l l l y t h i t h u j tinh ngodi bao...vi6c l l y manh ghdp k i t mgc ria khd khan vd khdng dam bao ehlt lirpng manh ghdp.
Vi ly do dd chOng tfli tien hdnh nghi&n cdu d l tdi vdi myc tieu'
Tim hiiu mdt sd ddc diim lidn quan chin ttod/j bdnh mdng thit & mit
D d i TU'CTNG VA PHU'ONG P H A P NGHIEN CLTU 1. Ddi typing nghien ciPU
Cdc b|nh nhdn mdng thit d i l u tri tgi Khoa Mit B$nh vian 103 vd Khoa Mdt Vidn Y hpc Hdng khflng tir thdng 7/2008 d i n 4/2009.
T/€(/ chuin /(i9 chgn benh nhdn
Cd b^nh dn nfli tru, dapc khdm vd c h i n dodn cdc bgnh m i t k i t hpp
Tidu chuan lo^i trd'
Mflng cd nguy&n nhdn vet thaong gidc mgc ho|ic mflng khflng d i l n hinh hodc b$nh nhdn khflng ding y tham gia nghi&n cdu
2. Phu'ang phdp nghi&n ciru Thiet ki nghidn CCPU: Mfl ta.
Phwang tidn nghien ciru - Thadc compa.
- Mdy sinh hien vi d&n khe gdn mdy chyp anh.
- H i so b&nh dn theo dfli b&nh nhdn, mdu b$nh dn nghi&n eiru, s6 sdeh ghi chep theo dfli b^nh nhdn.
Phuxmg phdp nghidn cuu a - T h i n g kd tr&n b$nh dn.
b - Khdm ldm sdng
+ Khdm tr&n smh h i l n vi ddnh gid:
- Vl tri mflng: Ci m i t phai hay m i t trdi, gdc trong, ngodi hay ca 2 gdc.
- Phdn dfl theo phdn loai eua Benh vl^n mit Trung aong [1]:
' Dfl I. D I U mflng vapt qud ria gide mac 1mm
* Dfl II: D i u mflng chaa tdi 1/2 bdn kinh gidc mgc,
* Dfl III: D i u mflng vapt qud 1/2 ban kinh glSc mgc.
" Dfl IV. D i u mflng tdi trung tdm gidc mge.
+ cac b$nh m i t li&n quan tr&n mat bi mflng.
Trdn eo sd kham iam sdng cd t h i t i l n hdnh phdn logi. mflng don, mflng k6p, mflng gdc trong, mflng gdc ngodi, mflng xo, mflng mdu vd phan d$ mflng (dO I, dfl II, dfl III, dfl IV), mflng cd b i n h m i t k i t hpp.
3. XD" ly s6 li^u
Cdc s l li§u sd- ly theo chaong trinh EPI - INFO 6.04 A eua T 6 chirc Y t l t h i gidi.
Y HOC IWJC HANH (895) - s6 llfliW
K£T QUA NGHIEN CI>U VA BAN LUAN Ldm sdng
Mflng d i l n hinh trfen ldm sdng Id mflt t l chde tdn tgo cua k i t mgc cd hinh tam gidc kdm theo x a mach xdm Idng qud ria vdo gidc mge.
Mflng rilm tuong Cmg vdi khe mi, chu y l u d gde trong (gflc mOi) hon d gdc ngodi {gdc thdi daong).
Mflng d t h i gdp d d hai gdc tr&n cCing mflt m i t gpi Id mflng kdp, d t h i gdp mflng d mflt m i t hode d hai m i t
Mflng d t h i ddy hay mdng t u j theo t l chirc lidn k i t mfl x o mgch dadi k i t mae nhilu hay It Kieh thyflrc eua mflng nhfl hay to khdc nhau tir 2mm d i n hon 10mm tinh theo mire dfl xdm l l n tCr ria gidc mgc d i n tmng tdm gidc mgc. Mdu s i c mflng cd t h i do, h i n g ho$c trlng bpt tuy theo s6 lapng mach mdu eua thdn mflng nhilu hay it, c6 cyong ty hay khdng.
Trong nhO'ng tradng hpp mflng t i l n triln ndng, mflng k&p, d i u mflng che phu todn bfl gidc mgc hode b i t ehdo nhau ngang qua gidc mgc, khdng e6n hinh dnh mflng d i l n hInh.
T i l n triln cda mflng thydng eh|m trong vdng nhilu ndm, ed t h i nhanh ehi trong vdng vdi thdng.
Qud trinh hinh thdnh mflng thadng qua hai giai doan (Comand, 1989) [7]:
- Giai dogn k i t mge: Giai dogn ndy thadng r l t ddi, d khi h i t ddi v l n khflng t i l n tnIn sang giai dogn sau vdi nhO'ng b i l u hi^n phii k i t mgc ria gdc trong, sung huylt k i t mge khe mi nhg, d t h i gidn mgch k i t mac vd co kdo cua k i t mgc nhdn c l u v l phia ria tgo ndn mdo cgnh ria. Giai dogn nay b&nh nhdn thydng cd triflu chirng kich thich nhg k i l u dj v^t, dde bi&t khi di gifl, ning.
- Giai dogn gidc mgc (mflng thyc thy): Sy g l ldn cCia mdo cgnh ria ldm m i t sy liln tyc cua phim nyde mit din d i n r l i logn dinh dydng vd hinh thdnh eac I lodt gidc mgc nhd. Qud trinh t>$nh 1^ ndy dapc ldp di ldp Igi tgo sgo vd sy xdm l l n cOa k i t mgc nhdn d u vdi diy tdn mgch vdo gide mgc hinh thdnh mflng diln hinh.
Qud trinh t i l n triln cue mflng cfl t h i gdy cdc b i l n chdng'
- Vi6m k i t mgc: Mflng bi kich thich vi&m dd tirng dtjrt, ddi khi lan ra cd p h l n k i t mgc Idnh eiia nhdn
du.
- Chly nydc mit: Do bj kleh thich bdi cdc nhdn t l mfli tardng (gid, byi, dnh sdna . .). Trong tradng hpp dinh mi - d u , d i l m 1$ cd t h i bj t r i gdy can trd lau thflng nydc m i t .
- Song thj: Do s y co rCit cua t l chde xo ldm hgn e h i van nhdn.
- Logn thj: S y co kdo gide mgc do mflng xdm l l n vdo Idm b i l n d i i dfl cong gidc mge, gdy n&n mflt loan thj khflng d i u .
- Khuylt thj tardng: Do mflng bd vdo tmng tdm ehe mflt p h l n ho$c todn bfl viing quang hpe eua gide mgc.
- Nang vCii b i l u md: Do s y b i l n logn to ehdc hpe eua mflng n6n b i l u mfl d t h i chui xulng dydi ldp d i m vd htnh thdnh nang chira djch d thdn ho$e d i u mflng.
- Hi&n tapng Dellen: Ld diem lodt gidc mac d i u mflng, ngay dadi chdn mdo go d i u mdng. Cd hi^n tapng ndy Id do film node mdt m i t s y li&n tyc tgi d i l m dd gdy r l i logn dinh dadng tao loet khfl, ddi khi gdy sirng hod tr&n m|t I lo&t
Phan loai
Cd ba cdch phan loai pho bien:
Phdn lo^i theo hinh thdi Idm sdng Da s l eae tae gia chia mflng iam hai logi:
- Mflng xo: Ld mdng khdng t i l n triln. Dau mflng nhd det, dadng xdm l l n eua dau mflng hgp, dao Fuchs nho vd khflng bat mdu Fluorescein gidc mgc Thdn mflng dgt, x o teo, it mach mau
- Mflng mdu (mflng thjt): Id mdng it tiln trien hay tien trien chdm, cd the kdo ddi tiln trien hdng chuc ndm D I U mdng ddy, rflng, dadng xdm l l n r6ng, dao Fuchs to Thdn mflng ddy do, cdc mach mdu caong ty, khi nhuflm Fluorescein phan gidc mgc tmde d i u mflng b i t mdu [7].
Theo Comand (1989) ngodi hai logi mflng tren d n ed mflt loai mflng dc tinh (malignant pterygium)' d i u mflng d t h i m ldu rflng. than mdng ldn, mgch mdu r l t caong tu, tiln tnIn r l t nhanh ve phia gidc mac.
PhSn dd mdng
Dya vdo s y xam ldng cua mflng vdo gidc mgc.
Tdc gia Comand (1989) phdn ra 3 dfl phdt tnIn cua mpng:
- Dfl V Ddy la hinh thdi sdm cua bflnh, mflng vapt qud ria gidc mgc 1-2mm, d i u mflng g l ldn tr&n gide mgc thdnh hinh bdn d u trlng hodc vdng, k i t mgc b i t d i u b| CO kdo v l phia d i u mflng. Thdn mflng khflng ddy, chira vdi mach mdu ehgy theo hadng vdo gide mgc.
- Dfl 11. Mflng dang d hinh thdi hogt dflng, d i u mflng xdm l l n vdo gidc mac 2-4mm d i n g i n trung tdm gidc mgc, cd t h i thiy dao Fuehs. Thdn mflng ddy, nhilu maeh mdu gidn Dfl rflng ciia e l mflng thay d l i tir 3-8mm
- Dfl III La hinh thdi t i l n triln eua mflng, d i u mflng xdm l l n qud 4mm vdo gide mac vting trung tdm gdy t i n thaong thi lyc trim trpng. nhin thiy dao Fuehs rfl. Thdn mflng ddy dd. mach mdu ddy do vd gidn rdng. C6 mflng rflng 8-10mm.
Cf Viflt Nam cdc tde gia phdn loat mflng theo cdch phdn loai cua Vien Mdt: L l y bdn kinh gidc mae Idm ehuln, ehia r a 4 d d [1]:
- Dfl r D i u mflng vapt qud ria gide mgc 1mm.
- Dfl II' Dau mflng ehaa tdi 1/2 ban kinh gidc mge - Dd 111: D i u mdng vaot qud 1/2 bdn kinh gidc mgc.
- Dfl IV: D i u mflng tdi tmng tam gidc mgc.
Phdn lo^i theo sw tdi phdt
Sy phdn loai ndy mang tinh qui adc, khdng ddnh gid dapc hinh thai Idm sdng vd ddc d i l m tiln triln cua mflng.
- Mong nguy&n phdt Mflng chaa dapc phdu thu^t l l n ndo
- Mflng tdi phdt: Mflng da phdu thu|t it nhit mflt lln.
{ HOC THVC HANH (895) - S6 12/2013
Bang I . S l lapng b#nh nhdn. s6 mit, mflnq vd s l mpnq nqhi&n ciru
ChisI Benh nhan
So mit So rriQnq S6 mOng nghi6n CLPU
Tinh chat monc Mpng do-n
1 mit 30 30 30 30
MOng don 2 mit
25 50 50 50
Mflng 8 8 16 11
6 laong Tong cpng 63 88 96 91 s l mdt dapc nghi&n ciru Id 88 trong do ed 80 mdt mdng don vd 8 mat mflng kep. Trong so mat cd mdng k&p chiing tdi loai khdi nghien ciru 5 mdt do mflng khflng dien hinh. Nha vay tong so mdng nghl&n eiru Id 91.
Bang 2. Ddc diem li&n quan chan doan do mdng mOng
II III IV COng
Nir SL 24 21 3 48
%
26,4 23.0 3,3 52,7
Nam SL 14 26 3 43
%
15,4 28,6 3.3 47,3
C SL 38 47 6 91
jng
%
41.8 51,6 6.6 100,0
So s^nh (P) 0,352
Ket qua nghien cdu cho thay ty le mflng dfl III, IV chilm 58,2% vd mdng dp II ehlem 41,8%. So benh nhdn nd cd mflng dfl II chiem 26,4% cao hon nam (15,4%). Ngaoc lai, d mdc mdng dfl 111 so b&nh nhdn nam chilm 28,6% cao hon so vdi nir (23,0%), Tuy vay, sa ch&nh lech khflng cd y nghTa thdng k&
(p>0,05).
D^c d i l m v l c h i n doan vj t r i mflng 63 bdnh nhdn cfl 17 benh nhan bj mdng mat phai (27,0%), 21 b§nh nhdn bj mflng m i t trdi (33,3%) va 25 b&nh nhdn bj mflng 2 mat (39,7%) Nghi&n cdu cho t h i y vj tri mflng cdc m i t Id taong daong nhau (p>0,05), Theo Ddng Xuan Y&n (2005) ty le benh nhdn bj mflng m i t phai Id 38,89% vd mdt trdi Id 35,18% [3] Nhu vay, ty Ig mflng glira hai m i t Id taong daong nhau (p>0,05).
Trong 91 mflng m i t dapc nghi&n eiru ehiing tfli g i p da s l mflng goe trong (90,9%), chi cd 9 , 1 % Id mflng k&p Sy khdc biet cd y nghTa thdng kd (p<0,001). Ddc bi&t trong nghien cdu cua Allza Jap cd d i n 31,4% mdt cd mflng kdp [4], ty I& m i t cd mflng k6p trong nghien cdu ciia chijng toi chi co 8/88 m i t chiem 9,1%. Chung tdi ggp da so mat cd mflng gflc trong (90,9%), chicd 8 mat = 9,1% ed mflng kep.
D i n g Xudn Y&n (2005) gap mflng gflc trong Id 97,22% vd mflng k&p \a 2,78% [3], Le Nha Tung (2007) gdp Id 92,2% mflng d gdc trong [2].
^%
0 % » , n , . e ^ Mgng don Mgng dem Mgng kep goe trong g6c ngodi
B i l u dfl 2. Phdn bd mpng
Dac d i l m li&n quan c h i n dodn hinh thdi m^ng Trong sd cdc mflng nghi&n ciru, chiing tfli gap chO y l u Id mflng xo (87,9%), mflng mdu chi chilm 12,1%
(p<0,001). K i t qua cho t h i y : mflng chD y l u gdp d hinh thai mflng x o (87,9%), cht ed 12,1% Id mflng mdu (p<0,001) K i t qua ndy cOng phd hpp vdi nghi&n cdu cua L& Nha TCing (2007): mflng xo ehilm 8,4%
vd mflng mdu ehilm 21,6% [2].
Bleu d l 3. Hinh thai mpng Ddc d i l m lien quan c h i n dodn b^nh mdt phii h p p
Bang 3 Cdc b&nh mdt p h i i hpp Bgnh mit phoi hpp
Da mo dyc thuy tinh t h i ngo^i bao 3^
Can cimg do, sgo KM do mSl hQl pa m l cit bfe cung giac mgc Nguy CO bl giflcom. gl6com dang
theo dOi, Jilutn Khong c6 bgnh mJt ph6i ho'p~
S6 lifpng I Ty 1$ (%)
Tong s6 mit j 68 I 100.0 Theo nghiln eiru eua ehiing tdi: s l m i t cd b$nh phii hop chilm 79,5%. Trong dd cd 31 m i t (35,2%) dd ml lly t h i thdy tinh ngodi bao, 13 m i t (14,8%) dd dupc ml cdt ba cung gidc mgc do bj b^nh giflcom. Cfl 15 mit (15,9%) can ciing dd, sgo giae mge do b|nh mit hflt cO, 12 mdt (13,6%) nghi ngd bi giflcom. K i t qua cua chting tdi cQng phii hpp vdi nghi&n cdu cCia Allza Jap: s l mat mflng tr&n m i t dd m l lay t h i thuy tinh ngoai bao chilm 39,2%, m i t bj gldcom, nghi ngd gidcom ehilm 21,6%
vd 7,8% seo k i t mac tmdc dd [4].
K £ T LUAN
Ty Ig cde dfl mflng Id taong daong khi so sdnh vdi nhau vd cQng khflng cd y nghTa thing kS khi so sdnh ty Id gi&a nam vd na (p>0,05).
Vj tri mflng cde m i t la taong daong nhau (p>0,05). Mflng m i t phai (27,0%), mflng mit trSi (33,3%) va mflng 2 m i t (39,7%).
Da so mflng gdc trong (90,9%), ehi cd 9,1% Id mflng kdp. Sy khdc bi$t cd •j/ nghia thing k6 (p<0,001).
Mdng ehu y l u gdp d hinh thdi mflng xo (87,9%), chicd 12,1% Id mflng mdu (p<0,001),
Ty 1$ m i t cd b&nh phdi hop taong d l i ldn (chilm 79,5%).
TAI LIEU THAM K H A O
1. Cii Nhin Ngi, Hodng Thj Luy, Hd Huy Tiln vd cflng sy (1996), Dieu tra djch te hpc mil lod vd mflt so bgnh ve mdt. Cdng trinh nghien cwu khoa hgc cap W.
Vign mat.
2 Le Nhu- Tung (2007), Ddnh gid hi$u qud cda phwcmg phdp dt mdng ghdp mdng 6i trong diiu W"
Y HOC THirC HANH (895) - S6 12/2013
mdng nguydn phdt Ludn vdn Thgc sT Y hpc. Tmdng Dgi hgc Y Hd Nfli.
3. D i n g Xuan Y&n (2005), Nghien cOv wng dpng phwcmg phdp ghdp kit m$c tw thdn tmng diiu trj mdng thjt tai B$nh vien 103 vd Vi$n qudn y 4. Ludn vdn t i t nghi&p bde sy chuy&n khoa e l p 11, Hgc vign Qudn y.
4. Aliza Jap et al (1999), Conjunctival Rotation Autograft for Pterygium Ophthamology, 106. pp 6 7 - 7 1 .
5 Astudilto t. M , Kenyon K. R. (1995). Rerygium.
Master technicques in ophthamic Surgery. William and
VWIkins. Philadelphia. (14). pp 110-120.
6. Chang-Ping Un et al (1997), Clinical experiences of infectious scleral ulceration, A complication of pterygum operation. Br J. Ophthalmol, 81, pp 980 - 983
7 Comand G. (1989), Pterygium: clinical course and treatment. Rev. Int Trach Pathol. Ocul. TnDp. Subtrop Sante. Pubtique, (66), pp 81 -108.
8. Jaros P. A., Deluise V P (1988). Pinguecular and pterygium. Ophthalmol, (33), pp 41- 49.
CHI TRA CHO VIEC THAM GIA CAC NGHIEN CUfU, THUT NGHIEM LAM SANG:
KHAO SAT THUC TRANG TAI VIET NAM
N G U Y E N N G O Q U A N G - Cue Khoa Hoc Cong Nghd & Ddo Tao, Bd Y Te DAO DLTC GIANG - FHI360 T6M TAT
Myc tidu: Tim hiiu viic chi trd cho cdc ddi twong tham gia cdc nghidn cO-u thu- nghiem Idm sdng t^i Vidt Nam, trdn ca sd dd dwa ra cdc khuyin cdo cho cdc Nghidn ciru vidn vd Hdi Ddng Dao Ddc lidn quan din vide chi trd cho cdc ddi twping tham gia nghidn cOu. Phwcmg phdp nghidn ciru: Nghidn ciru khdo sdt cit ngang sw dpng bdng cdu hdi ciu trdc. Ket qud: Djnh mdo vd cdch thirc chi trd cho cdc ddi tWQrng tham gia cdc nghidn cuv, thir nghi$m Idm sdng tai Vidt Nam cd s y khdc bi$t rit Idn giira cdc co sd nghidn cCru cOng nhw trong cung mdt ca s& nghidn cOii. Phin Idn cdc khodn thanh todn cho vi$c tham gia vdo nghidn ciru cda bdnh nhdn dwoc thwc hidn bing tiin mdt. vd cdc nghidn ciru vidn diu hiiu ring ddy Id khodn tiin ddnh cho vide di 1^1 vd cho vi$c tham gia vdo nghidn ciru. Tuy nhidn phin tdn cdc ca s& nghidn cdv khdng cd cdc quy dmh cp thi vd thdng nhit vi djnh mirc vd cdch thCrc chi trd. Hdi ddng dgo ddc ddng vai trd quan trpng trong vide thim djnh djnh mdc chi trd cho bdnh nhdn tham gia vdo nghidn ciru, tuy nhidn vin di chi trd cho b$nh nbdn giwdng nhw chwa dwQV thdnh vidn Hdi ddng Dao dire quan tdm ddng muc. Kit lu$n: Vi$c chi trd cho cdc ddi tw^ng tham gia nghidn ciru ldm sdng hidn nay cd sw khdc bi$t l&n vd chwa cd cdc chuin myc Idm cdn cw cho vide chi trd. Hdi ddng dao ddc cin xdy dpng cdc hw&ng din cp thi lidn quan din dinh mirc vd cdch thirc chi trd dwa trdn cdc quy c^nh hidn hdnh, phd hep v&i tOng lo^i hinh, hodn cdnh vd tinh chit phirc t$p cOa nghidn cOv di trdnh vi$c chi trd Idm dnh hwdng din vdn di d^o ddc nghidn ciru.
TO- khda: HOI Ddng D90 Dire, Ddi tw&ng tham gia nghidn cOv, Chi trd nghidn ciru, Nghidn ciru Idm sdng.
SUMMARY
Objectives: We examined current payment practices to clinical research participants in Vietnam to make recommendations for clinical research investigators and ethics committee members Methods: Cross-sectional study using a stmctured
questionnaire. A diverse sample of clinical investigators and ethics committee members were selected. Results: Reimbursement practice is highly variable between and within research institutions.
Where the payment occurs. It Is largely monetary and it is for travel expenses and compensation for times taking part into trials Most of the research institutions do not have any guidances or policies on amounts and mechanism for reimbursement for research participants. Ethics committees were reported to be often involved in decision making around.
Conclusions: Payment to clinical research participants vary in Vietnam. Ethics committees have an important mle in developing guidelines in this area. Specific guidelines are needed considering local policies and regulations, payment models and their application in diverse settings, types and levels of reimbursement, and the rationale for diverse payment practices In different settings.
Keywords: Payment practices. research participants, research investigators, ethics committee members.
DAT VAN D £
Mflt trong nhang cdu hdi md Hfli Oing Dao Ddc, Nghien ciru vien cung nha d l i tapng tham gia nghi6n edu quan tdm thadng hdi Id v l n de ehi tra eho vi&e tham gia vdo nghidn cdu Vi&e tham gia vdo nghign cdu dti Id nghi&n ciru don gian nha mdt cude phdng v l n vd danh vdi bfl cdu hdi ngin, hay mflt thLr nghiflm Idm sdng vdi thdi gian theo dfli mflt vdi ndm thi ddi tapng tham gia eung phai ddnh mflt khoing thdi gian n h i t djnh cho nghi&n edu, trong thdi gian ndy d l i tapng nghi&n edu khdng tgo ra dapc thu nhdp, do v$y vi&c ehi tra mflt khoan tien cho d i i typng tham gia nghien ciru Id mflt thflng le dapc dp dung khdng chi tgi Vi&t Nam md cdn d nhilu nydc khdc trfin t h i gidi V l n de d$t ra Id chi tra bao nhi&u vd chi trd nha t h i ndo de dam bao v l n d l dgo dire nghI6n ciru, VI$c ehi tra qua nhilu se iam cho khodn t i i n chi t r i ed tinh c h i t du dfl, ldi k6o d l i typng tham gia vdo nghi&n ciru, chi tra qud It ho$c khflng chi trd
Y HOC T H V C HANH (895) - SO 12/2013
