BIOCHEMISTRY
F. HISTORY OF BIOCHEMISTRY
40. The historical significance of the suffix "-esc" for enzymes catalyzing synthetic processes - M. A. Marginson.
BIOCHEMISTRY 125 PUBLISHED WORK
Book
l . McQUILLAN, M T. - Somatostatin Volume I , 1977. Annual Research Reviews, Series ed D. F. Horrobin, Eden Press, Montreal.
Chapters of Books
2. SCHREIBER, G. and URBAN, J. - The Synthesis and Secretion or Albumin, in Rev.
Physiol. Biochem. Pharmacol.. Vol.82. Springer-Verlag, Berlin, 28-95 (1978).
3. SIMS, N. R. and CARNEGIE, P. R. - 2',3'-Cyclic Nucleotide 3'-Phosphodiestcrase, in Advances in Neuroehemistry, Vol. 3. ed B. W. Agranofr and M . H. Aprison, Plenum Press, New York, 1-41 (1978).
4. SIMS, N . R., HORVATH, L., CARNEGIE, P. R„ BERNARD, C. C. A. and MACKAY, I . R. - A Search for thc "Multiple Sclerosis Virus" - Lack or Effect or Brain Extracts on Myelin Development in Chickens, Mice and Rats in Advances in Exp. Medicine and Biology. Vol. 100. Mvelination and Demyelination. ed J. Palo, Plenum Press. New York, 411-422 (1978).
Articles
5. CHANDRASENA. S. I . and HIRD, F. J. R. - Comparative Aspects or Adenylic Acid Deaminase and Aspartale-2-Oxoglutarate Aminotransferase. Comp. Biochem. Phvsiol. 61B:
191-194 (1978).
6. CHRISTOPHERSON, R. I . and FINCH, L. R. - Response or the Pyrimidine Pathway or Escherichia coli K12 to Exogenous Adenine and Uracil. Eur. J. Biochem. 90: 347-358 (1978).
7. CORNISH, E. C , CUSSEN. C. M., HIRD, F. J. R. and TODD, P. E. E. - Comparative Aspects o( Aminotransferases in the Rat, Pigeon and Rainbow Trout. Comp. Biochem.
Phvsiol. 6IB: 375-378 (1978).
8. COVENTRY, M . J., HILLIER. A. J. and JAGO, G. R. - The Metabolism or Pyruvate and Citrate in the Thermoduric Cheese Starter Streptococcus faecium (Streptococcus duransl.
Aust. J. Dairy Technol. 33: 148-154 (1978).
9. DREHER, f . W., GRANT, B. R. and WETHERBEE, R. - The Wound Response in the Siphonous Alga Caulerpa simpliciuscula C. Ag.: Fine Structure and Cytologv. Proloplasma 96: 189-203 (1978).
10. GETHING, M . -J. and DAVIDSON, B. E. - Chorismate Mutase/Prephenate Dehydratase from Escherichia coli KI2. Effect or Phenylalanine, NaCl and pH on the Protein Conformation. Eur. J. Biochem. 86: 159-164 (1978).
11. GETHING, M . -J. and DAVIDSON. B. E. - Chorismate Mutase/Prephenate Dehydratase from Escherichia coli K12. Binding Studies with thc Allosteric Effector Phenylalanine. Eur. J.
Biochem. 86: 165-174 (1978).
12. HAIGH, E. A. and SAWYER, W. H. - Interpretation o( Double Reciprocal Plots Used to Determine the Spectroscopic Parameters or Bound Licand for Binding Assays. Aust. J. Biol.
Sci. 3 i : i-5 (1978).
13. HAIGH, E. A., THULBORN, K. R., SAWYER, W. H. and NICHOL, L. W. - Uptake or n-(9-Anthroyloxy) Fattv Acid Fluorescent Probes into Lipid Bilaycrs. Aust. J. Biol. Sci. 31:
447-457 (1978).
14. HILLIER, A. J. and JAGO. G. R. - Metabolism o( [l 4C] Bicarbonate by Streptococcus lactis:
Identification and Distribution oT Labelled Compounds. J. Dairy Research 45: 231-240 (1978).
15. HILLIER, A. J. and JAGO, G. R. - Thc Metabolism or ["C] Bicarbonate by Streptococcus lactis: the Synthesis or Succinic Acid. J. Dairy Research 45: 423-431 (1978).
16. HILLIER, A. J. and JAGO, G. R. - The Metabolism o( ["C] Bicarbonate by Streptococcus lactis: the Fixation or ["C] Bicarbonate bv Pyruvate Carboxylase. J. Dairy Research 45: 433- 444 (1978).
17. HILLIER, A. J., RICE, G. H. and JAGO, G. R. - Metabolism or [, 4C] Bicarbonate by Streptococcus lactis: the Synthesis, Uptake and Excretion or Aspartate by Resting Cells. J.
Dairy Research 45: 241 -246 (1978).
18. HILLIER, A. J., RICE, G. H. and JAGO. G. R. - Transport o( Purine Bases by Streptococcus lactis. J. Dairy Research 45: 277-282 (1978).
19. HILLIER, A. J. and JAGO, G. R. - The Biosynthesis or Flavour Compounds in Cheddar Cheese. CSIRO Food Research Quarterly 38: 1-5 (1978).
20. HILLIER, A. J., JAGO, G. R., LLOYD, G. T. and BARLOW, I . - The Aerobic Formation o( Acetate from Pyruvate by Lactobacillus bulgaricus. Aust. J. Biol. Sci. 31: 565-571 (1978).
21. HURRELL, J. G. R., SMITH, J. A. and LEACH, S. J. - The Detection or Five Antigenicallv Reactive Regions in the Soybean Leghaemoglobin a Molecule.
Immunochemistry 15: 297-302 (1978).
126 FACULTY OF MEDICINE
22. LEACH,S.J. - Proteins in Australia. Trends in Biochemical Sciences 3: N 179-N180 (1978).
23. LEES, G. J. and JAGO, G. R. - Role of Acetaldehyde in Metabolism. A Review. Part 1.
Enzymes Catalvsing Reactions involving Acetaldehyde. J. Dairy Sci. 61: 1205-1215 (1978).
24. LEES, G. J. and JAGO, G. R. - Role of Acetaldehyde in Metabolism. A Review. Part I I . The Metabolism of Acetaiue'nyue in Cultured Dairy Products. J. Dairy Sci. 61: 1216-1224 (1978).
25. MITCHELL, A., SIN, I . L. and FINCH, L. R. - Enzymes of Purine Metabolism in Mycoplasma mycoides subsp. mycoides. J. Bacteriol. 134: 706-712 (1978).
26. PATERSON. Y. and LEACH, S. J. - The Effect of Refinements in Energetic Statistical Weighting on the Computed Chain Dimensions of Homopolypeptides. Macromolecules 11:
415-418 (1978).
27. PATERSON, Y. and LEACH, S. J. - The Effect of Side-Chain Branching on the Theoretically Predicted Conformational Space Available to Amino Acid Residues.
Macromolecules 11: 409-415 (1978).
28. PATERSON, Y. and LEACH, S. J. - The Random Coil Dimensions of Sequential Copolypeptides Containing N'-(2-Hvdroxvethvl)-L-glutamine. I . Theoretical Studies.
Macromolecules 11: 418-424 (1978).
29. RICE. G. H., HILLIER. A. J., JAGO, G. R. and STEWART, F. H. C. - The Uptake of Amino Acids and Peptides bv Streptococcus lactis. J. Dairy Research 45: 93-107 (1978).
30. ROGERS. K. M. and AUGUSTEYN, R. C. - Glutathione Reductase in Normal and Cataractous Human Lenses. Exp. Eye Research 27: 719-721 (1978).
31. SAWYER, W. H., BALDO, B. A., STICK, R. V. and UHLENBRUCK. G. - Purification and Characterization of a Galactan-reactive Agglutinin from the Clam Tridacna maxima (Roding)and a Studv of its Combining Site. Biochem. J. 175: 461-417 (1978).
32. SAWYER, W. H. and THULBORN, K. R. - A Polarization Instrument for Delecting Phase Transitions in Natural and Artificial Membranes. Trends in Fluorescence I : 28-30 (1978).
33. SMITH, J. A., HURRELL, J. G. R. and LEACH, S. J. - Elimination of Nonspecific Adsorption of Serum Proteins by Sepharose-Bound Antigens. Analytical Biochem. .87: 299- 305 (1978).
34. THULBORN, K. R. and SAWYER, W. H. - Properties and the Locations of a Set of Fluorescent Probes Sensitive to thc Fluidity Gradient of the Lipid Bilayer. Biochim. Biophvs.
Acta 511: 125-140 (1978).
35. THULBORN. K. R., SAWYER, W. H. and TRELOAR, F. E. - A Microviscosity Barrier in the Lipid Bilayer due to the Presence of Phospholipids containing Unsaturated Acvl Chains.
Biochem. Biophys. Res. Commun. 81: 42-49 (1978).
36. TRIKOJUS, V. M . Biochemistry Comes lo Australia. Trends in Biochemical Sciences 3:
N174-NI78 (1978).
37. TRUSCOTT, R. J. W., AUGUSTEYN, R. C. and FAULL, K. - The Identification of Anthranilic Acid in Proteolytic Digests of Cataractous Lens Proteins. Ophthal. Res. 9: 263- 268 (1977).
38. WRIGHT, S. W. and GRANT, B. R. - Properties of Chloroplasts Isolated from Siphonous Algae. Effects of Osmotic Shock and Detergent Treatment on Intactness. Plant Phvsiol. 61:
768-771 (1978).
THESES PASSED FOR HIGHER DEGREES Doctor of Philosophy
1. EDWARDS, K. J. - Biosynthesis of Albumin in Rat Liver
2. REYNOLDS. E. C. — Thymidine Sensitivity of Murine Myeloma and Lymphoma Cells 3. SMITH, J. A. — Synthesis. Structure and lmmunochemistry of Peptide Sequences in Globins
and Staphylococcal Nuclease
Master of Science
4. GREEN, S. M . - Effect of Fumarate on the Metabolism o f Streptococcus lactis 5. THOMAS, M . P. - Aspects of the Metabolism of Pyruvate by Streptococcus lactis
THESES IN PROGRESS PhD Theses in Progress
BYRT, P. N. — Biochemical Investigations in Phytophthera cinnamomi CHELLADURAI, M. — Intermediate Forms of Secretory Proteins
CH'NG, A. L. — Uptake. Storage and Excretion of Nitrogenous Compounds by Marine Benthic Algae
DAVULURI, SIVAPRASAD - Amino Acid Metabolism in relation to End-Products of Nitrogen M etabolism
BIOCHEMISTRY 127 DREHER, T. W. — The Biochemistry of the Wound Response in the Algal Genus Caulerpa EAST, I. J. — Immunogenicity and Antigenicity of Globin Proteins
EVANS. D. J. — Studies on the Synthesis and Tertiary Structure of Peptides and their Relationship to Protein Folding
HAIGH, E. A. — Fluorescent Probes as Indicators of Membrane Structure
HAWTHORNE, D. B. — Structure and Function of 1.3-fi Linked Glucans Found in Siphonous Algae
HICKEY, M. W. — Aspects of the Carbohydrate and Amino Acid Metabolism of Lactobacilli HUDSON, G. S. — Comparative Studies of Chorismate Mutase-Prephenate Dehydratase and Chorismate Mutase-Prephenate Dehydrogenase of E. coli K12
NAGASHIMA, M. — Studies on the Synthesis and Secretion of Glycoproteins
PATERSON, Y. J. - The Effect of Side-Chain Complexity on the Dimensions of Polypeptide Chains
RADFORD, I. R. - Effect of Cytotoxic Drugs on DNA Synthesis
SMALL, D. H. — Synthesis of Myelin Basic Protein in relation to Multiple Sclerosis Serum Factors
THULBORN, K. R. - n-(9-Anthroyloxy) Fatty Acids as Fluorescent Probes for Biomembranes WRIGHT, S. W. — Special Properties Associated with Chloroplasts of Siphonous Green Algae
MSc Theses in Progress
BUI, A. H. - H . — Cations Transport and Membrane Fluidity of Human Blood Lymphocytes (jointly with Dept. of Medicine, Austin Hospital)
CHANDRASENA, S. I . — The Functional Significance of Aspartate Aminotransferase CORNISH, E. C. — Investigations into the Nature and Structure of the Tyr R Gene Product of Escherichia coli (jointly with Microbiology Dept.)
DAVIES, W. D. — Use of DNA Sequencing to Study Regulation of Aromatic Amino Acid Synthesis in E. coli
DAVY, R. M . — The Effect o f Altered Haem-Ligand Binding and other Modifications on the Properties of Cytochrome c
LEVERTON, S. A. - Cataractous Lens Proteins
MITCHELL, J. - Nucleotide Contents and DNA Synthesis in Fibroblasts Treated with Hydroxyurea
STONE, F. H. — Hydroxyurea Sensitivity of Three Types of Murine Tumour Cells MAgrSc Thesis in Progress
SYKES, G. E. - Regulation of Development of Seed Proteins
SUBSTANTIAL GRANTS RECEIVED (over $5,000) Grants have been received as follows:
Anti-Cancer Council of Victoria: The Metabolism of Transferrin and a ,-Antitrypsin in Morris Hepatoma 5123TC.
ARGC: Structure and Function of Myelin Proteins.
ARGC: Comparative Studies of the Three Isofunclional DAHP Synthetase from Escherichia coli K l 2 (with Microbiology Dept.).
ARGC: Structure and Function of Enzymes involved in the Synthesis of Phenylalanine and Tyrosine in E. coli.
ARGC: Chloroplast Metabolism.
ARGC: The Redox Properties of Leghaemoglobin-Ligand Complexes: a Probe of Hacm-Pockel Structure.
ARGC: Amino Acid Biosynthesis during Photosynthesis of Marine Algae.
ARGC: Evolutionary Aspects of Biochemistry.
ARGC: Effect of Side Chain Complexity on Peptide Conformation.
ARGC: The Structure and Evolution of Primitive Haemoglobins.
Australian Wool Corporation: Synthesis and Conformation of Peptides forming p-Turns in Proteins.
NH & MRC: Oxidation during Senile Nuclear Cataract Formation.
NH & MRC: Phosphorylation of Myelin Basic Protein and Multiple Sclerosis.
NH & MRC: Synthesis anil Secretion of Protein by the Liver.
128 FACULTY OF MEDICINE
NH & MRC: Diagnostic. Biosynthetic and Molecular Studies on Hacmoglohinopathics (with Dept.
oT Haematology, Queen Victoria Hospital).
National Institutes of Health: Thc Mechanism of Senile Cataract Formation.
National Multiple Sclerosis Societv: Characterization of Antibrain Factors in Sentni from Patient5
with Multiple Sclerosis.
In addition. 9 grants of between $1,000 and S5.000 were received from the following donors:
Australian Research Grants Committee; Forests Commission. Victoria; Medical Research Committee. University of Melbourne: Research and Graduate Studies Committee. University of Melbourne; Rowden While Estate.