Animal Reproduction and
Development
Modes of Reproduction
• Sexual reproduction
– Meiosis, gamete formation, and
fertilization
– Offspring show genetic variation
• Asexual reproduction
Stages of Development
Gamete formation
Fertilization
Cleavage
Gastrulation
Organ formation
Development Overview
frog egg
frog sperm
midsectional views Eggs form and mature in female
reproductive organs, and sperm form and mature in male
reproductive organs.
A sperm and an egg fuse at their plasma membrane, then the nucleus of one fuses with the nucleus of the other to form the zygote.
By a series of mitotic cell divisions, different daughter cells receive different regions of the egg cytoplasm.
Cell divisions, migrations, and rearrangements produce two or three primary tissues, the
forerunners of specialized tissues and organs.
Subpopulations of cells are sculpted into specialized organs and tissues in prescribed spatial
Gamete formation
Fertilization
Cleavage
Gastrulation
Male
seminal vesicle
prostate gland
bulbourethral gland
urethra bladder
Spermatogenesis
• Spermatogonium (2n) divides by
mitosis to form primary spermatocyte (2n)
Testicular Cells
• Sertoli cells
– Line the seminiferous tubules
– Nourish the developing sperm
• Leydig cells
– Lie between the seminiferous tubules
Female Reproductive Organs
oviduct
vagina uterus ovary
cervix vagina
uterus
Menstrual Cycle
• The fertile period for a human female occurs on a cyclic
basis
• Menstrual cycle lasts about 28
Fertilization
• Sperm penetrates to egg cytoplasm
Pregnancy
• Averages 38 weeks from fertilization • Takes two weeks for blastocyst to
form
Early Divisions
• Cleavage begins within 24 hours of fertilization
Day 1 Day 2 Day 3 Day 4
Day 5 -
Blastocyst Forms
• Cell secretions produce a fluid-filled cavity in center of ball of cells
• Layers of blastocyst
– Inner cell mass – Trophoblast
– Blastocoel
inner cell mass
Implantation Begins
• Blastocyst attaches to endometrium (UTERUS) ;
begins to burrow into maternal
blastocoel
inner cell
Extraembryonic Membranes
DAY 14
yolk sac
chorionic cavity chorionic
villi
chorion
amniotic cavity
connecting stalk
• The amniotic
membrane will enclose embryo
• Yolk sac forms
• Chorion begins to
Human Chorionic
Gonadotropin (HCG)
• Hormone secreted by the blastocyst
• Stimulates corpus luteum to keep making progesterone and estrogens
• This maintains endometrium, prevents menstruation
Gastrulation - Day 15
• Primitive streak
forms along one axis of the inner cell mass
• Cells migrate
inward here to form endoderm and
Gastrulation
• Sphere of cells is a blastula
• During
gastrulation, some cells move inward
• Produces a
Vertebrate Body Plan Emerges
paired neural folds
somites
The Placenta
• Interlocking fetal and maternal
tissues
• Performs digestive, respiratory, and urinary functions for the
fetus
• Materials exchanged across
4 weeks
8 weeks
Embryonic Period
• Weeks 3 to 8
• By the close of embryo
period
– Appears human
Week 4
Fetal Period
• Weeks 9 to birth
• Fetus is initially about 1 inch long
• Fetus born before 22 weeks cannot
survive
Fetal Nutrition
• All nutrients for fetal growth and
development must be delivered via the placenta
• Mother’s diet affects fetal health
• Smoking may affect ability to absorb
Birth (Labor)
• Cervical canal dilates
• Amniotic sac ruptures
• Uterine contractions drive fetus from uterus
• Placenta is expelled as
Lactation
• During pregnancy, progesterone
and estrogen stimulate gland development
• After birth, prolactin induces
synthesis of enzymes for milk production
Stages of Human
Development - Prenatal
• Zygote - Single cell
• Morula - Solid ball of cells
• Blastocyst - Ball with fluid-filled cavity
• Embryo - 2 weeks to 8 weeks
Stages of
Human
Development -
Postnatal
• Newborn - First 2 weeks after birth
• Infant - 2 weeks to 15 months
• Child - 10-12 years
• Pubescent - At puberty • Adolescent - Puberty
to maturation • Adult
Birth Control Options
Prevent fertilization
Prevent ovulation
Sexually Transmitted
Diseases (STDs)
• Worldwide epidemic of STDs
• Women are most affected
• Can cause infertility, pain,
Causative Agents of STDs
• Viruses
– AIDS (HIV)
– Genital herpes
(Herpes simplex)
– Genital warts
(HPV)
• Bacteria
– Gonorrhea
(Neisseria
gonorrhoeae)
– Syphilis
(Trepnema pallidum)
– Chlamydial
In Vitro Fertilization
• Conception outside the body
• Woman receives hormone injections to stimulate ovulation
• Oocyte is removed and combined with sperm in petri dish
Abortion
• Removal of blastocyst, embryo, or
fetus
• First trimester abortions are painless,
and relatively complication free
• Later abortions are more difficult and