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Table 1Effect of 20 h treatment with staurosporine (STS) or NMDA on rat cortical cell cultures on LDH leakage, nucleosome formation, and caspase-3 activity
Fig. 2A, it can be seen that with NMDA, LDH leakage of48 units that occurs between 20 and 48 h is comparable tothe 57 unit increase in control cells
Fig. 3. TUNEL staining of neurons exposed to staurosporine for 20 or 48 h. Cells were treated by removing the cell culture media and replacing with aserum-free balanced salt solution containing 500 nM staurosporine or vehicle (0.5% DMSO) which remained for
Table 2Effect of 4-day pre-treatment with 500
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