BAB VII SIMPULAN DAN SARAN
7.2 Saran
DAFTAR PUSTAKA
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LAMPIRAN Lampiran I
Lampiran II
Hasil analisa Alpha Lipoic Acid 100mg GNC
KEMENTERIAN RISET, TEKNOLOGI, DAN PENDIDIKAN TINGGI UNIVERSITAS UDAYANA
UPT. LAB. ANALITIK
Kampus Bukit Jimbaran, Telp. 0361701954, HP.081803134550
Lampiran 1
No Kode Sampel Alpha Lipoic
Acid (%) METODE
1 Sampel 1 100 HPLC
Bukit Jimbaran, 29 Maret 2016 Kepala UPT Laboratorium Analitik Universitas Udayana
IDA BAGUS PUTRA MANUABA
Lampiran III
KOMPOSISI ALA GNC 100MG
Kegunaan: Dapat digunakan untuk penderita diabetes.
Petunjuk Penggunaan: Minum satu atau dua kapsul lunak sehari.
Directions: Take one or two softgel capsules daily.
Other Ingredients: Soybean oil, Gelatin from bovine, Glycerin (from Vegetable), Riboflavin, Titanium Dioxide (Natural Mineral Whitener).
Potency verified by GNC procedure#5275.
Conforms to USP <2091> for weight.
Meets USP <2040> disintegration.
Peringatan & Perhatian:
- Hanya untuk penderita kencing manis yan g telah ditetapkan oleh dokter.
- Selama penggunaan, konsultasikan pada dokter secara berkala.
- Penggunaan dosis tinggi sebaiknya dihindari karena dapat menyebabkan hipoglikemia (sakit kepala, dizziness, fatigue) yang biasanya dihubungkan dengan kadar gula darah rendah.
- Apabila gejala berlanjut konsultasikan kepada tenaga medis/dokter.
Penyimpanan di luar jangkauan anak-anak KEEP OUT OF REACH OF CHILDREN Simpan di tempat sejuk dan kering
Store in a cool, dry place.
Komposisi
Tiap kapsul lunak mengandung:
Alpha Lipoic Acid (from Thioctic Acid) 100mg
Lampiran IV Produk GNC ALA 100mg
Lampiran V Data Berat Badan Tikus
No BB Awal Panjang dalam cm BB 4 mg
Kontrol 1 269 19 280
2 280 20 285
3 274 19.5 281
4 284 19 285
5 270 19.6 286
6 288 18 269
7 272 18.5 271
8 291 19 275
9 276 19.6 280
10 291 19.4 279
P1 1 281 19.5 266
2 283 19.5 257
3 279 19 261
4 280 19.2 279
5 284 19.3 243
6 285 20 258
7 286 19.7 257
8 281 19.4 244
9 283 19.4 260
10 285 19.7 254
P2 1 280 19.2 215
2 283 19.5 213
3 285 19.5 209
4 287 19.9 201
5 286 19.8 205
6 289 20 219
7 280 19 213
8 287 19.8 231
9 279 19 224
10 281 19 209
Kontrol : Pakan normal
P1 : Pakan Normal + Aktivitas Fisik (renang)
P2 : Pakan Normal + Aktivitas Fisik (renang) + ALA per-oral
Lampiran VI Analisa pre-post BB
Paired Samples Test Paired Differences
t df Sig. (2-tailed) 95% Confidence
Interval of the Difference
Mean
Std.
Deviation
Std. Error
Mean Lower Upper
Pair 1 P0pre - P0post .400 11.683 3.694 -7.957 8.757 .108 9 .916 Pair 2 P1pre - P1post 24.800 11.478 3.630 16.589 33.011 6.833 9 .000 Pair 3 P2pre - P2post 69.800 9.841 3.112 62.760 76.840 22.429 9 .000
Lampiran VII Data Pemeriksaan Berat Lemak
N 0
PENGUKURAN LEMAK SUB KUTAN, ABDOMEN DAN VISCERAL PADA TIKUS PUTIH
Kontrol Pakan normal, renang sedang
Pakan normal, renang sedang dan ALA
SC Visc SC visc SC visc
1 2,0 1,6 1,3 0,9 0,9 0,6
2 1,7 1,8 1,4 1,2 0,3 0,4
3 1,6 1,1 1,5 0,9 0,4 0,6
4 2,9 3,3 1,3 1,1 0,8 0,5
5 1,4 1,1 2,0 1,3 0,4 0,5
6 2,2 2,6 1,1 1,9 0,7 0,7
7 1,3 1,9 1,5 2,4 0,5 0,3
8 2,2 3 1,8 1,9 0,8 1,4
9 2,4 3,2 1,0 1,3 0,9 1,6
10 2,2 3,1 1,7 1,7 0,9 1,3
Lampiran VIII Analisis Deskriptif
Berat Badan (gram)
Kelompok N Mean Std. Deviation Minimum Maximum
Kelompok P0 10 279.10 5.840 269 286
Kelompok P1 10 257.90 10.311 243 279
Kelompok P2 10 213.90 8.925 201 231
Total 30 250.30 28.829 201 286
Berat Lemak Subkutan Abdominal (gram)
Kelompok N Mean Std. Deviation Minimum Maximum
Kelompok P0 10 1.990 .4932 1.3 2.9
Kelompok P1 10 1.460 .3098 1.0 2.0
Kelompok P2 10 .660 .2366 .3 .9
Total 30 1.370 .6571 .3 2.9
Berat Lemak Visceral Abdominal (gram)
Kelompok N Mean Std. Deviation Minimum Maximum
Kelompok P0 10 2.190 .7637 1.1 3.2
Kelompok P1 10 1.460 .4949 .9 2.4
Kelompok P2 10 .790 .4630 .3 1.6
Total 30 1.480 .8134 .3 3.2
Lampiran IX Uji Normalitas Data
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk Statistic df Sig. Statistic df Sig.
Berat Badan (gram) Kelompok P0 .193 10 .200* .914 10 .309
Kelompok P1 .182 10 .200* .928 10 .429
Kelompok P2 .151 10 .200* .968 10 .871
Berat Lemak Subkutan Abdominal (gram)
Kelompok P0 .165 10 .200* .954 10 .713
Kelompok P1 .149 10 .200* .976 10 .940
Kelompok P2 .223 10 .173 .856 10 .068
Berat Lemak Visceral Abdominal (gram)
Kelompok P0 .156 10 .200* .932 10 .464
Kelompok P1 .227 10 .156 .918 10 .341
Kelompok P2 .277 10 .028 .837 10 .061
Lampiran X Uji Homogenitas Data
Test of Homogeneity of Variance
Levene Statistic df1 df2 Sig.
Berat Badan (gram) Based on Mean .564 2 27 .576
Based on Median .578 2 27 .568
Based on Median and with adjusted df
.578 2 22.088 .569
Based on trimmed mean
.564 2 27 .576
Berat Lemak Subkutan Abdominal (gram)
Based on Mean 2.579 2 27 .094
Based on Median 2.145 2 27 .137
Based on Median and with adjusted df
2.145 2 19.394 .144
Based on trimmed mean
2.710 2 27 .085
Berat Lemak Visceral Abdominal (gram)
Based on Mean 2.902 2 27 .072
Based on Median 2.408 2 27 .109
Based on Median and with adjusted df
2.408 2 26.875 .109
Based on trimmed mean
2.896 2 27 .073
Lampiran XI Analisis Komparasi
ANOVA Sum of Squares df
Mean
Square F Sig.
Berat Badan (gram) Between Groups 22121.600 2 11060.800 150.776 .000 Within Groups 1980.700 27 73.359
Total 24102.300 29
Berat Lemak Subkutan Abdominal (gram)
Between Groups 8.966 2 4.483 34.029 .000
Within Groups 3.557 27 .132
Total 12.523 29
Berat Lemak Visceral Abdominal (gram)
Between Groups 9.806 2 4.903 14.110 .000
Within Groups 9.382 27 .347
Total 19.188 29
Lampiran XII Uji Lanjutan dengan LSD
Multiple Comparisons LSD
Dependent
Variable (I) Kelompok (J) Kelompok
Mean
Difference (I-J) Std. Error Sig.
95% Confidence Interval Lower Bound Upper Bound Berat Badan
(gram)
Kelompok P0 Kelompok P1 21.200* 3.830 .000 13.34 29.06
Kelompok P2 65.200* 3.830 .000 57.34 73.06
Kelompok P1 Kelompok P0 -21.200* 3.830 .000 -29.06 -13.34
Kelompok P2 44.000* 3.830 .000 36.14 51.86
Kelompok P2 Kelompok P0 -65.200* 3.830 .000 -73.06 -57.34
Kelompok P1 -44.000* 3.830 .000 -51.86 -36.14
Berat Lemak Subkutan Abdominal (gram)
Kelompok P0 Kelompok P1 .5300* .1623 .003 .197 .863
Kelompok P2 1.3300* .1623 .000 .997 1.663
Kelompok P1 Kelompok P0 -.5300* .1623 .003 -.863 -.197
Kelompok P2 .8000* .1623 .000 .467 1.133
Kelompok P2 Kelompok P0 -1.3300* .1623 .000 -1.663 -.997
Kelompok P1 -.8000* .1623 .000 -1.133 -.467
Berat Lemak Visceral Abdominal (gram)
Kelompok P0 Kelompok P1 .7300* .2636 .010 .189 1.271
Kelompok P2 1.4000* .2636 .000 .859 1.941
Kelompok P1 Kelompok P0 -.7300* .2636 .010 -1.271 -.189
Kelompok P2 .6700* .2636 .017 .129 1.211
Kelompok P2 Kelompok P0 -1.4000* .2636 .000 -1.941 -.859
Kelompok P1 -.6700* .2636 .017 -1.211 -.129
*. The mean difference is significant at the 0.05 level.
Lampiran XIII Foto Foto Penelitian Kelompok Kontrol
Kelompok 1