Supplemental Digital Content 5D: Statistical analysis of conclusive results in suction group stratified by age.
CONCLUSIVE SUCTION > 36M
Proportion meta-analysis
Method: Stuart-Ord (inverse double arcsine square root) Stratum Responding Total
1 87 152 Croffie, 2007
2 35 46 Hayes, 2012
3 1965 2298 Montedonico, 2008
4 866 1012 Pini-Prato, 2007
Stratum Proportion 95% CI (exact)
1 0,572368 0,489668 0,652191 Croffie, 2007 2 0,76087 0,612331 0,874139 Hayes, 2012 3 0,855091 0,84003 0,869242 Montedonico, 2008 4 0,855731 0,832556 0,876814 Pini-Prato, 2007 Stratum Standardized effect Variance % Weights (fixed, random)
1 0,572368 0,006557 4,344729 24,61807 Croffie, 2007
2 0,76087 0,021505 1,324786 18,129916 Hayes, 2012
3 0,855091 0,000435 65,48433 28,846176 Montedonico, 2008
4 0,855731 0,000988 28,846154 28,405838 Pini-Prato, 2007 Fixed effects (inverse variance)
Pooled proportion = 0,843845 (95% CI = 0,831651 to 0,855664) Non-combinability of studies
Cochran Q = 63,055209 (df = 3) P < 0,0001
Moment-based estimate of between studies variance = 0,035212 I2 (inconsistency) = 95,2% (95% CI = 91,5% to 96,9%)
Random effects (DerSimonian-Laird)
Pooled proportion = 0,77609 (95% CI = 0,688349 to 0,852962) Bias indicators
Begg-Mazumdar: Kendall's tau = -0,666667P = 0,0833 (low power) Egger: bias = -4,481771 (95% CI = -15,459369 to 6,495827) P = 0,2211 Harbord: bias = -6,329814 (92,5% CI = -20,641559 to 7,98193) P = 0,2673
CONCLUSIVE SUCTION < 36M
Proportion meta-analysis
Method: Stuart-Ord (inverse double arcsine square root) Stratum Responding Total
1 146 168 Alizai, 1998
2 33 33 Campeotto, 2011
3 30 39 Granstrom, 2011
4 142 153 Hall, 2008
5 68 85 Hall, 2008
6 160 222 Athow, 1990
7 52 65 Yang, 2013
8 280 355 Khan, 2003
Stratum Proportion 95% CI (exact)
1 0,869048 0,808473 0,916079 Alizai, 1998
2 1 0,894237 1 Campeotto, 2011 [97,5% one-sided CI]
3 0,769231 0,606738 0,888663 Granstrom, 2011 4 0,928105 0,875002 0,963566 Hall, 2008
5 0,8 0,699207 0,878958 Hall, 2008
6 0,720721 0,65676 0,778681 Athow, 1990
7 0,8 0,682312 0,888984 Yang, 2013
8 0,788732 0,742532 0,830041 Khan, 2003
Stratum Standardized effect
Variance % Weights (fixed, random)
1 0,869048 0,005935 14,991103 13,743845 Alizai, 1998
2 1 0,029851 2,980427 9,594282 Campeotto, 2011 [97,5%
one-sided CI]
3 0,769231 0,025316 3,514235 10,176823 Granstrom, 2011
4 0,928105 0,006515 13,656584 13,601199 Hall, 2008
5 0,8 0,011696 7,606762 12,447028 Hall, 2008
6 0,720721 0,004494 19,795374 14,111411 Athow, 1990
7 0,8 0,015267 5,827402 11,759232 Yang, 2013
8 0,788732 0,002813 31,628114 14,56618 Khan, 2003
Fixed effects (inverse variance)
Pooled proportion = 0,819364 (95% CI = 0,79634 to 0,841296) Non-combinability of studies
Cochran Q = 51,849664 (df = 7) P < 0,0001
Moment-based estimate of between studies variance = 0,049362 I2 (inconsistency) = 86,5% (95% CI = 74,6% to 91,4%)
Random effects (DerSimonian-Laird)
Pooled proportion = 0,840459 (95% CI = 0,773238 to 0,897764) Bias indicators
Begg-Mazumdar: Kendall's tau = -0,142857P = 0,5484 (low power) Egger: bias = -2,699944 (95% CI = -11,278457 to 5,878569) P = 0,4705 Harbord: bias = 2,165745 (92,5% CI = -2,954931 to 7,28642) P = 0,398
