Effect of Cinnamon on Immune Responses to an Exhaustive Exercise Session in Active Boys

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Effect of Cinnamon on Immune Responses to an Exhaustive Exercise Session in Active Boys

Mohsen Salesi3

 , Maryam Koushkie Jahromi2 1 ,

gerd al T Moradi an

s Has

1.Department of Sports Sciences, Faculty of Education and Psychology, Shiraz University, Shiraz, Iran.

2.Corresponding author, Faculty of Sports Sciences, Department of Education and Psychology, Shiraz University, Shiraz, Iran.

3. Department of Sports Sciences, Faculty of Education and Psychology, Shiraz University, Shiraz, Iran.

Article Info ABSTRACT

Article type:

Research

Article history:

Received:

28 April 2023 Received in revised form:

30 May 2023 Accepted:

31 May 2023 Published online:

22 June 2023

Keywords:

Cinnamon,

Exhaustive exercise, Lymphocytes, Monocytes, Neutrophils.

Introduction: Various environmental and genetic factors, such as inflammation caused by intense sports activity affect the immune system response of athletes.

One way to prevent the inflammatory process and help the immune system is probably to take anti-inflammatory drugs such as cinnamon. This study aimed to investigate the effect of one-week cinnamon supplement consumption on the immune responses to one session of exhaustive exercise in active boys.

Methods: This quasi-experimental study was conducted in a single-blind method.

The statistical population of the research was male collegiate athletes of Shiraz University. Twelve healthy subjects (age: 22 ± 1.93 years, height: 172.56 ± 6.56 cm, weight: 66.56 ± 11.54kg) participated in the study voluntarily and in a crossover method. Two participants refused to continue the research due to the injury. Participants performed Bruce's exhaustive exercise test in two situations of supplement consumption and placebo. Participants consumed 500 mg of cinnamon supplement or a similar placebo per day before exercise sessions for one week.

Blood samples were taken before and 15 minutes following the exercise. A dependent t-test was used for data analysis and a significant level was set at p<0.05.

Results: Cinnamon supplementation did not have a significant effect on the number of monocytes before and after exhaustive exercise (P=0.154), but cinnamon supplementation reduced significantly exercise-induced changes in neutrophils (decrease), lymphocyte (increase), and neutrophil to lymphocyte ratio (decrease). P values were 0.015, 0.012, and 0.02, respectively.

Conclusion: Daily consumption of 500 mg of cinnamon supplement for one week reduces the body's immune response following exhaustive physical activities, and thus, improves performance and strengthens the athletes' immune system.

Cite this article: Moradi Talgerd H., Koushkie Jahromi M., & Salesi M. Effect of Cinnamon on Immune Responses to an Exhaustive Exercise Session in Active Males. Journal of Sport Biosciences. 2023; 15 (2):17-29.

DOI: https://doi.org/10.22059/jsb.2023.356437.1579

Journal of Sport Biosciences by University of Tehran Press is licensed under CC BY-NC 4.0.

| Web site: https://jsb.ut.ac.ir/ | Email: [email protected].

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Introduction

Various environmental and genetic factors, such as inflammation caused by intense physical activities, affect the immune system response of athletes. The response of the body's immune system to physical activities is one of the important topics that has been considered in recent years from the point of view of health and professional sports. Based on available studies, exercise has a double effect on the function of the immune system in such a way that regular and moderate-intensity exercises improve the function of the immune system. While the intensity of physical activities increases to the point of exhaustion, the performance of the immune system decreases in the early hours after the activity. Immune system changes are related to inflammation. Pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF- α) lead to the modification of immune cells and their migration and also initiate and strengthen acute phase and stress reactions. Sometimes, following an intense physical activity that constitutes a major part of sports training during the athlete's competition, a period of suppression of the immune system occurs and increases the risk of infection. In addition to exercise, nutrition can also affect the function of the immune system, therefore, the use of various nutritional programs, especially the use of some supplements is important in improving the body's immune function during physical activities. A group of nutritional factors whose effects on various inflammatory indicators have been examined are herbal medicines such as cinnamon. Cinnamon is the dried bark of the Cinnamomum Zeylanicum plant stem from the Lauraceae family. For compounds such as coumarin, eugenol, cinnamaldehyde, and cinnamic acid in cinnamon, the anti-inflammatory effect has been proven. The research results indicate that the composition of cinnamaldehyde in cinnamon stimulates the immune system by inhibiting the production of nitric oxide, it inhibits the nuclear factor kappa-light-chain-enhancer of activated B cells (NF- kB), which plays a key role in regulating the immune response to infection. Considering that physical activities are associated with inflammatory reactions which cause changes in the immune system, in this research, the effect of cinnamon supplementation on immune responses following a session of physical activity was investigated.

Methods

This quasi-experimental study was conducted in a single-blind method. The statistical population of the

University. Twelve healthy subjects (Mean age: 22 ± 1.93 years, mean height: 172.56 ± 6.56 cm, mean weight: 66.56 ± 11.54 kg) participated in the study voluntarily and in a crossover method. Two participants refused to continue the research due to the injury. Participants performed Bruce's exhaustive exercise test in two situations of supplement consumption and placebo. Participants consumed 500 mg of cinnamon supplement or a similar placebo per day before exercise sessions for one week. Blood samples were taken before and 15 minutes following the exercise. A dependent t-test was used for data analysis and a significant level was set at p<0.05.

Results

Cinnamon supplementation did not have a significant effect on the number of monocytes before and after exhaustive exercise (P=0.154), but cinnamon supplementation reduced significantly exercise- induced changes in neutrophils (decrease), lymphocyte (increase), and neutrophil to lymphocyte ratio (decrease). P values were 0.015, 0.012, and 0.02, respectively.

Conclusion

Daily consumption of 500 mg of cinnamon supplement for one week reduces the body's immune response following exhaustive physical activities, and thus, improves performance and strengthens the athletes' immune system.

Ethical Considerations

Compliance with ethical guidelines: All the participants filled the consent form to participate in the research and the ethics committee of Shiraz University has approved all the phases of conducting this research.

Funding: Financial resources were provided by the authors.

Authors’ contribution: All the authors have contributed equally in

conducting this research

Conflict of interest: The authors declared no conflict of interest.

Acknowledgments: The authors thank all the participants who supported us in this research.

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،ﺪﺻرد ﻞﯿﻓﻮﻨﯾزﻮﺋا ﺎﻫ

3 / 2 ﯿﻓوزﺎﺑ ،ﺪﺻرد ﻞ

ﺎﻫ 4 /0 ﺖﯿﺳﻮﻧﻮﻣ ،ﺪﺻرد ﺎﻫ

3 /5 و ﺪﺻرد ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ

30 ﺪﺻرد ﻞﯿﮑﺸﺗ ار ﺎﻬﻧآ ﻣ

ﯽ ﺪﻨﻫد ) 2 .(

ﺶﻫوﮋﭘ ﺎﻫ ي ﺞﯾﺎﺘﻧ ﺎﺑ يدﺎﯾز رد ﯽﻔﻠﺘﺨﻣ

ﮥﻨﯿﻣز ﻪﮐ ﺖﺳا هﺪﯿﺳر تﺎﺒﺛا ﻪﺑ و مﺎﺠﻧا نارﺎﮑﺷزرو ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ دﺮﮑﻠﻤﻋ ﯽﺳرﺮﺑ ﻞﻣاﻮﻋ

ﺤﻣ ﻒﻠﺘﺨﻣ ﯿ

ﻄ ﯽﮑﯿﺘﻧژ و ﯽ ﺷﺎﻧ بﺎﻬﺘﻟا ﺪﻨﻧﺎﻣ

ﯽ ﻟﺎﻌﻓ زا ﯿ ﺖ ﺷزرو ﯽ ﺪﺷ ﯾﺪ ﺳ ﺦﺳﺎﭘ ﺮﺑ ﯿ

ﻢﺘﺴ اﯾ ﻨﻤ ﯽ نارﺎﮑﺷزرو ﺛﺄﺗ

ﯿﺮ ﻣ ﯽ دراﺬﮔ . ﺮﺑ ﺎﭘ ﮥﯾ ﻦﯾا

ﺶﻫوﮋﭘ ﺎﻫ شزرو ﺛﺄﺗ ﯿﺮ د ﻪﻧﺎﮔو ا ي ﺳ دﺮﮑﻠﻤﻋ ﺮﺑ ﯿ

ﻢﺘﺴ اﯾ ﻨﻤ ﯽ دراد

، ﻪﺑ ﻪﻧﻮﮔ ا ي ﺮﻤﺗ ﻪﮐ ﯾ تﺎﻨ ﻂﺳﻮﺘﻣ تﺪﺷ ﺎﺑ و ﻢﻈﻨﻣ ﺐﺟﻮﻣ

دﺮﮑﻠﻤﻋ دﻮﺒﻬﺑ

ﺳ ﯿ ﻢﺘﺴ اﯾ ﻨﻤ ﯽ ﻣ ﯽ ﺪﻧﻮﺷ ) 3 ( ، ﻟﺎﺣرد ﯽ ﻪﮐ اﺰﻓا ﺎﺑ ﯾ ﺶ ﻟﺎﻌﻓ تﺪﺷ ﯿ

ﺖ ﺷزرو ﯽ ﺪﺣ ﺎﺗ ﮔﺪﻧﺎﻣاو ﯽ ﺳ دﺮﮑﻠﻤﻋ ، ﯿ

ﻢﺘﺴ اﯾ ﻨﻤ ﯽ ﻟوا تﺎﻋﺎﺳ رد ﯿﻪ

ﺲﭘ زا

ﻟﺎﻌﻓ ﯿ ﺖ ﺶﻫﺎﮐ ﻣ ﯽ ﯾ ﺪﺑﺎ ﺳ دﺮﮑﻠﻤﻋ ﻒﯿﻌﻀﺗ ﺐﺟﻮﻣ و ﯽﻨﻤﯾا ﻢﺘﺴﯿ

ﻣ ﯽ دﻮﺷ ) 4 .(

هداد نﺎﺸﻧ تﺎﻘﯿﻘﺤﺗ ﻪﮐ ﺖﺳا

ﻟﺎﻌﻓ ﯿ ﺖ ﺷزرو ﯽ ور دﺎﺣ ي ﺦﺳﺎﭘ

ﺎﺳ ﯾ ﺎﮐﻮﺘ ﯾ ﻦ ﺎﻫ ﻟا ﻞﻣاﻮﻋ و ﺑﺎﻬﺘ

ﯽ ﺮﺛﺆﻣ ﺖﺳا

، ﻪﺑ ﻪﻧﻮﮔ ا ي ﻪﮐ ﻦﯾﺎﮐﻮﺘﯾﺎﺳ ﺎﻫ

ي ﺶﯿﭘ ﺑﺎﻬﺘﻟا ﯽ ﺶﺷ ﻦﯿﮐﻮﻟﺮﺘﻨﯾا ﺪﻨﻧﺎﻣ ﺎﻔﻟآ رﻮﺘﮐﺎﻓ و6

ي رﻮﻣﻮﺗ زوﺮﮑﻧ

7

دﺮﮑﻠﻤﻋ ﻞﯾﺪﻌﺗ ﺐﺟﻮﻣ لﻮﻠﺳ

ﺎﻫ ي ﻨﻤﯾا ﯽ ﺎﻬﻧآ تﺮﺟﺎﻬﻣ و ﻞﺤﻣ ﻪﺑ

بﺎﻬﺘﻟا ﻣ ﯽ ﺪﻧﻮﺷ و ﺶﻨﮐاو ﺎﻫ ي ﺖﯾﻮﻘﺗ و عوﺮﺷ ار سﺮﺘﺳا و دﺎﺣ زﺎﻓ

ﻣ ﯽ ﺪﻨﻨﮐ ) 5 .(

ﻦﯿﻨﭽﻤﻫ ﯽﺧﺮﺑ ﻦﯾﺎﮐﻮﺘﯾﺎﺳ ﺎﻫ

ﺷﺎﻧ بﺎﻬﺘﻟا ﻞﺤﻣ ﻪﺑ ﯽ

ﺘﻓﺎﺑ ﺐﯿﺳآ ﺎﯾ نژﻮﺗﺎﭘ زا ﯽ

ﺎﻫر ﻣ ﯽ ﺪﻧﻮﺷ ﻞﯿﻓوﺮﺗﻮﻧ دورو و ﺎﻫ

ﺳﻮﻧﻮﻣ ، ﯿ ﺖ ﺎﻫ و

ﺮﮕﯾد لﻮﻠﺳ ﺎﻫ ي د ﺮﯿﮔرد ر زﺎﺴﮐﺎﭘ ي ﺘﻧآ ﯽ نژ ﻞﯿﻬﺴﺗ ار ﻣ

ﯽ ﺪﻨﻨﮐ ﻓﺎﺑ دﻮﺒﻬﺑ ﺐﺒﺳ و ﺖ

ﻣ ﯽ ﺪﻧﻮﺷ ) 6 .(

رد ﻣز ﯿﻨ ﮥ ﺛﺄﺗ ﯿﺮ ﺮﺑ ﺪﯾﺪﺷ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ

ﺦﺳﺎﭘ ﺎﻫ ي ،ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ ﻞﻣاﻮﻋ ﯽﻨﯿﺋﺎﮔ

نارﺎﮑﻤﻫ و )

2011 (،

ﺎﺑ ﯽﻘﯿﻘﺤﺗ رد ﮥﺴﯾﺎﻘﻣ

ﺖﻓﺎﯾزﺎﺑ عﻮﻧ ود ﻏﯿ

لﺎﻌﻓﺮ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ زا ﺲﭘ لﺎﻌﻓ و

هﺪﻧﺎﻣرد زﺎﺳ ﻪﮐ ﺪﻧداد نﺎﺸﻧ نارﺎﮑﺷزرو نادﺮﻣ يور ﺮﺑ ﻟﺎﻌﻓ

ﯿ ﺖ ﺷزرو ﯽ دﺎﺣ ﻣ ﯽ ﺪﻧاﻮﺗ ﺰﻓا ﺐﺟﻮﻣ اﯾ

ﺶ رادﺎﻨﻌﻣ داﺪﻌﺗ ﺖﯿﺳﻮﮑﻟ ﺎﻫ ﻞﯿﻓوﺮﺗﻮﻧ ، ﺎﻫ

،

ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ﺳﻮﻧﻮﻣ و ﯿ ﺖ ﺎﻫ نﻮﺧ رد

،دﻮﺷ ﺖﯿﻟﺎﻌﻓ ﻊﻄﻗ و

، دﻮﺷ ﯽﺘﺣاﺮﺘﺳا ﺮﯾدﺎﻘﻣ ﺎﺗ ﺮﯾدﺎﻘﻣ ﻦﯾا ﺶﻫﺎﮐ ﺐﺟﻮﻣ ﺖﻓﺎﯾزﺎﺑ و )

7 .(

ﻦﯿﻨﭽﻤﻫ

يرﺎﮔدﺎﯾ نارﺎﮑﻤﻫ و )

2017 ﯽﻘﯿﻘﺤﺗ رد ( ﮥﻨﯿﻣز رد

ﺛﺄﺗ ﯿﺮ يزاﻮﻫ ﺖﯿﻟﺎﻌﻓ ﻪﺴﻠﺟ ﮏﯾ ﭘﯿ

ﺶ هﺪﻧور ﺮﺑ ﺪﯾﺪﺷ ﯽﺑوﺎﻨﺗ و ﺖﯿﺳﻮﮑﻟ داﺪﻌﺗ

ﺎﻫ و

ﺖﮐﻼﭘ ﺎﻫ ي يزاﻮﻫ ﺖﯿﻟﺎﻌﻓ ﻪﺴﻠﺟ ﮏﯾ ياﺮﺟا ﻪﮐ ﺪﻧداد نﺎﺸﻧ رﺎﮑﺷزروﺮﯿﻏ نادﺮﻣ نﻮﺧ ﭘﯿ

ﺶ هﺪﻧور ﺪﯾﺪﺷ ﯽﺑوﺎﻨﺗ و ﻣ

ﯽ ﺪﻧاﻮﺗ ﺶﯾاﺰﻓا ﺐﺟﻮﻣ

دﺎﻘﻣ رادﺎﻨﻌﻣ ﯾﺮ

ﺖﯿﺳﻮﮑﻟ ﺎﻫ ﻞﯿﻓوﺮﺗﻮﻧ ﻞﻣﺎﺷ) ي ﺎﻫ

، ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ﺖﯿﺳﻮﻧﻮﻣ و ﺎﻫ

دﺎﻘﻣ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ زا ﺲﭘ ﺖﻋﺎﺳ ود و ﺪﻧﻮﺷ ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ ( ﺮﯾ

ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ﺶﻫﺎﮐ ﯽﻣ ﺪﺑﺎﯾ ﺮﯾدﺎﻘﻣ ﻪﺑ و ﺎﭘ

ﯿﯾ ﻦ ﺮﺗ ﯽﺘﺣاﺮﺘﺳا حﻮﻄﺳ زا ﻣ

ﯽ ﺪﺳر ) 1 نارﺎﮑﻤﻫ و ﺲﻧﺮﺠﯾو .(

) 2000 ﻖﯿﻘﺤﺗ رد ( يور يﺮﮕﯾد

ﻪﮐ ﺪﻧداد نﺎﺸﻧ ﯽﺘﻣﺎﻘﺘﺳا نارﺎﮑﺷزرو

،ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ ﻊﻄﻗ زا ﺲﭘ ﺖﺳرد ﯽﻨﻌﯾ ﺖﻓﺎﯾزﺎﺑ ياﺪﺘﺑا رد ﯿﺳﻮﮑﻟ داﺪﻌﺗ

ﺖ ﺎﻫ ﻪﺑ ﺖﺸﮔزﺎﺑ ﻪﺑ عوﺮﺷ

ﯽﺘﺣاﺮﺘﺳا ﺮﯾدﺎﻘﻣ ﻣ

ﯽ ﺪﻨﮐ ﻫﺎﮔ و ﯽ 15 ﺎﺗ 60 ﺶﻫﺎﮐ ﺎﺑ ،ﺪﯾﺪﺷ رﺎﯿﺴﺑ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ زا ﺲﭘ ﻪﻘﯿﻗد ﺎﻨﻌﻣ

راد ﺖﯿﺳﻮﮑﻟ ﯽﺧﺮﺑ ﺎﻫ

ﺮﺘﻤﮐ ﯽﺘﺣ زا

دﺎﻘﻣ ﯾﺮ ﻪﺟاﻮﻣ ﯽﺘﺣاﺮﺘﺳا ﻣ

ﯽ ﻮﺷ ﯾ ﻢ ) 8 (.

ﻪﮐ ﺖﺳا هداد نﺎﺸﻧ تﺎﻘﯿﻘﺤﺗ ﺞﯾﺎﺘﻧ ﺲﭘ

ﻟﺎﻌﻓ زا ﯿ ﺖ ﺷزرو ﯽ ﺪﺷ ﯾﺪ ﺒﺴﭼ ﯿ نﺪ ﺳﻮﮑﻟ ﯿ ﺖ ﺎﻫ ﻓوﺮﺗﻮﻧ ، ﯿ ﻞ ﺎﻫ و

ﺳﻮﻧﻮﻣ ﯿ ﺖ ﺎﻫ ﻪﺑ ﻻ ﮥﯾ ﻠﺧاد ﯽ و قوﺮﻋ ﭘ رد ﯽ ﺳﻮﮑﻟ تﺮﺟﺎﻬﻣ نآ ﯿ

ﺖ ﺎﻫ ﺮﻃ زا ﯾ ﻖ ﻻ ﮥﯾ ﻠﺧاد ﯽ ﻞﺧاد ﻪﺑ قوﺮﻋ دﯾ

راﻮ ة ﺺﺨﺸﻣ ﻞﺣاﺮﻣ قوﺮﻋ

بﺎﻬﺘﻟا ﺖﺳا ) 9 .(

ﻦﯾاﺮﺑﺎﻨﺑ ﺐﻗﺎﻌﺘﻣ ﮏﯾ ﺖﯿﻟﺎﻌﻓ زرو ﺷ ـ ﯽ ﺑ ـﺎ ﺷ ـ ﺪ ت ز ﯾـ ﺎد ﮐ ـ ﻪ ﺶﺨﺑ هﺪﻤﻋ ا ي زا ﺎﻨﯾﺮﻤﺗ ت زرو ﯽﺷ ز ﺎﻣ ن ر ﺖﺑﺎﻗ زرو ﺷ ـ ﺎﮑ ر نا

Neutrophils

1.

Eosinophils

2.

Basophils

3.

4. Lymphocytes Monocytes

5.

Interleukin 6(IL6)

6.

α) - Alfa(TNF -

Tumor Necrosis Factor

7.

(5)

ﺛﺄﺗ ﯿ ﺮ اد ﭼر ﯿ ﻦ ﺦﺳﺎﭘ ﺮﺑ ﺎﻫ ي اﯾ ﻨﻤ ﯽ ﯽﭘ رد ﯾ ﮏ ﻟﺎﻌﻓ ﻪﺴﻠﺟ ﯿ ﺖ ﺷزرو ﯽ هﺪﻧﺎﻣاو لﺎﻌﻓ ناﺮﺴﭘ رد زﺎﺳ

21

ار ﻞﯿﮑﺸﺗ ﻣ ﯽ ﺪﻫد

، ﮏﯾ هرود ﻮﮐﺮﺳ ب د ﺎﮕﺘﺳ ه ا ﯽﻨﻤﯾ ا ﺎﻔﺗ ق ﻣ ﯽ ﻓا ﺪﺘ ﻼﺘﺑا ﺮﻄﺧ و رﺎﮑﺷزرو

اﺰﻓا ار ﺖﻧﻮﻔﻋ ﻪﺑ ﯾ

ﺶ ﻣ ﯽ ﺪﻫد ) 10 .(

او رد ﻊﻗ

ﺖﯿﻟﺎﻌﻓ زرو ﺷ ـ ﯽ ﺷ ـ ﺪﯾﺪ داﺪﻌﺗ ﺖﯿﺳﻮﮑﻟ ﺎﻫ ي ﺮﮔ شد ﻮﺧ ن ار ﺎﺗ ﻦﯾﺪﻨﭼ ﺮﺑا ﺮﺑ ﻮﻄﺳ ح ا ﺮﺘﺳ ا ﯽﺘﺣ ا ﺰﻓ ا ﺶﯾ ﺶﻫﺎﮐ ﺎﯾ ﻣ ﯽ ﺪﻫد و ﺗـ ﺎ ﺖﻋﺎﺳ ﺎﻫ ﺲﭘ

زا ﺖﯿﻟﺎﻌﻓ زرو ﯽﺷ ﺰﯿﻧ ا ﻦﯾ و ﺖﯿﻌﺿ ﻣ ﯽ ﺪﻧاﻮﺗ ادا ﻪﻣ ﺪﺑﺎﯾ ﻦﯾا و ﺮﯿﯿﻐﺗ تا ﺮﯿﮕﻤﺸﭼ رد ﻌﺗ ﺪ دا و ﻮﺗ زﯾ ـ ﻊ ﺳﻮﮑﻟ ـ ﺖﯿ ﻫ ـﺎ ي ﺮﮔ شد ﻮﺧ ن ز و ﺮﯾ هدر ﺎﻫ ي

نآ ﺐﺒﺳ ﻢﻫﺮﺑ ﻮﺧ ندر و ﺿ ـ ﺖﯿﻌ راﺪﯾﺎﭘ ﺪﺑ ن نارﺎﮑﺷزرو ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ دﺮﮑﻠﻤﻋ ﻒﯿﻌﻀﺗ و ﻣ

ﯽ دﻮﺷ ) 11 .(

هوﻼﻋ ﺮﺑ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ

، ﺬﻐﺗ ﯾﻪ ﻧﯿ ﺰ ﻣ ﯽ ﺪﻧاﻮﺗ ﺳ دﺮﮑﻠﻤﻋ ﺮﺑ ﯿ

ﻢﺘﺴ اﯾ ﻨﻤ ﯽ ﺮﺛﺆﻣ

،ﺪﺷﺎﺑ اﺮﺑﺎﻨﺑ ﯾ ﻦ زا هدﺎﻔﺘﺳا ﻪﻣﺎﻧﺮﺑ

ﺎﻫ ي ﺬﻐﺗ ﯾﻪ ا ي نﻮﮔﺎﻧﻮﮔ

ﻪﺑ وﯾ هﮋ فﺮﺼﻣ ﻞﻤﮑﻣ ﺎﻫ ي اﺬﻏ ﯽﯾ اﺮﺑ ي ا دﺮﮑﻠﻤﻋ ندﺮﺑ ﻻﺎﺑ ﯾ

ﻨﻤ ﯽ ﻟﺎﻌﻓ مﺎﮕﻨﻫ نﺪﺑ ﯿ

ﺖ ﺷزرو ﯽ ﻤﻫا ﯿ ﺖ ﯾ ﻪﺘﻓﺎ ) ﺖﺳا 12 (.

ا رد ﯾ ﻦ ﺑﯿ ﻦ

ﻞﻤﮑﻣ ﺎﻫ ي ﮔ ﯿ ﻫﺎ ﯽ ﻪﺑ ﮐﺮﺗ ﻦﺘﺷاد ﺐﺒﺳ ﯿ

تﺎﺒ ز ﯾ ﺘﺴ ﯽ و لﺎﻌﻓ تاﺮﯿﺛﺄﺗ ﻓ ﯿﺰ ﯾ ژﻮﻟﻮ ﯾﮑ ﯽ هدﺮﺘﺴﮔ ا ي ﺪﻧراد نﺪﺑ ﺮﺑ ﻪﮐ

، ﺑﯿ ﺮﺘﺸ راﺮﻗ ﻪﺟﻮﺗ درﻮﻣ

ﻪﺘﻓﺮﮔ ﺪﻧا

، ﻪﺑ ﻪﻧﻮﮔ ا ي ا ﻪﮐ ا زا هدﺎﻔﺘﺳ ﯾ

ﻦ ﻞﻤﮑﻣ ﺎﻫ ﺑ رد ﯿ ﻦ رد نارﺎﮑﺷزرو ﻫد

ﮥ اﺰﻓا ﻪﺘﺷﺬﮔ ﯾ

ﺶ ﮕﻤﺸﭼ ﯿﺮ ي ﺖﺳا ﻪﺘﺷاد )

13 .(

ﯾ ﮏ زا هوﺮﮔ

ﻞﻣاﻮﻋ ﺬﻐﺗ ﯾﻪ ا ي ﻪﮐ ﺛﺄﺗ ﯿﺮ ﺮﺑ نآ ﺺﺧﺎﺷ ﺎﻫ ي ﺑﺎﻬﺘﻟا ﻒﻠﺘﺨﻣ ﯽ

ﺳرﺮﺑ ﯽ هﺪﺷ

، ﺎﻫوراد ي ﮔ ﯿ ﻫﺎ ﯽ ﭼراد ﻪﻠﻤﺟ زا ﯿ

ﻦ ﺖﺳا ﻦﯿـﭼراد . ﺖـﺳﻮﭘ1

ﮏﺸﺧ ﺪﺷ ة ﻗﺎـﺳ ﮥ هﺎـﯿﮔ

Zeylanicum Cinnamomum

زا ــﺧ داﻮﻧﺎ ة گﺮﺑ ﻮﺑ )

Lauraceae

( ﺖﺳا ) 14 ﮐﺮﺗ .(

ﯿ تﺎﺒ ﮑﺸﺗ ﯿ ﻞ ﺪﻨﻫد ة ﭼراد ﯿ ﻦ

ﺴﻠﮐ ﻞﻣﺎﺷ ﯿ

،ﻢ و ،ﺪﻨﻗ ﯾ ﻣﺎﺘ ﯿ ﻦ وC

ﻧﺪﻌﻣ داﻮﻣ ،K

ﯽ ،ﻦﻫآ ﻞﻣﺎﺷ ﺰﻨﮕﻨﻣ

و ور ي ﺖﺳا ) 15 .(

نﺎﺸﻧ ﺪﻫاﻮﺷ ﻣ

ﯽ ﺪﻨﻫد ﭼراد ﻪﮐ ﯿ ﻦ اراد ي ﻟﻮﻨﻓ ﯿ

،ﮏ

ﺋﻮﻧوﻼﻓ ﯿﺪ ﺎﻫ و هدﻮﺑ ﻧﯿ ﺰ اراد ي تاﺮﯿﺛﺄﺗ ﺑﺎﻬﺘﻟاﺪﺿ ﯽ ﺖﺳا ) 16 ( ياﺮﺑ . ﺗﺎــﺒﯿﮐﺮﺗ ﯽ ﻈﻧ ﺪﯿـﺳا ﮏﯿﻣﺎﻨﯿﺳ و ﺪﯿﻫﺪﻟآ مﺎﻨﯿﺳ ،ﻞــﻧژوا ،ﻦﯾرﺎــﻣﻮﮐ ﺮــﯿ

ﭼراد رد دﻮﺟﻮﻣ ﯿ

ﻦ ﺑﺎﻬﺘﻟاﺪـﺿ ﺮـﺛا ﯽ

) ﺖﺳا هﺪﯿـﺳر تﺎـﺒﺛا ﻪـﺑ 15

ﺎﺘﻧ .(

ﯾ ﺞ ﺶﻫوﮋﭘ ﺎﻫ ﮐﺎﺣ ﯽ ﮐﺮﺗ ﺖﺳا نآ زا ﯿ

ﺐ رد دﻮﺟﻮﻣ ﺪﯿﻫﺪﻟآ مﺎﻨﯿﺳ

ﭼراد ﯿ ﻦ ﺮﺤﺗ ﺐﺒﺳ ﯾ

ﮏ ﺳ ﯿ ﻢﺘﺴ اﯾ ﻨﻤ ﯽ ) 17 ﻟﻮﺗ رﺎﻬﻣ ﺎﺑ و ( ﯿﺪ

ﺮﺘﻧ ﯾ ﮏ ﺎﺴﮐا ﯾﺪ ﺐﺟﻮﻣ رﻮﺘﮐﺎﻓ رﺎﻬﻣ ﻪﺘﺴﻫ

ا ي ﺎﭘﺎﮐ ﺠﻧز ﯿﺮ ة ﮏﺒﺳ ﺪﻨﻫددﻮﺒﻬﺑ ة

لﻮﻠﺳ

لﺎﻌﻓB

ﺸﻘﻧ ﻪﮐ2

ﯽ ﻠﮐ ﯿﺪ ي ﻈﻨﺗ رد ﯿ ﻢ ا ﺦﺳﺎﭘ ﯾ ﻨﻤ ﯽ دراد ﺖﻧﻮﻔﻋ ﻪﺑ

، ﻣ ﯽ دﻮﺷ ) 18 .(

ﺗ ﺎﺑ ﻪﺟﻮ ا ﻪﺑ ﯾ ﻪﮑﻨ ﺮﻤﺗ ﯾ تﺎﻨ ﺷزرو ﯽ ﺪﯾﺪﺷ ﺎﺑ ﺶﻨﮐاو ﺎﻫ ي ﺑﺎﻬﺘﻟا ﯽ ﺖﻧﻮﻔﻋ و بﺎﻬﺘﻟا و ﺖﺳا هاﺮﻤﻫ

ﻋ و ا ﯽﺷﺎﻧ ﺖﻧﻮﻔ نآ ز

ﻧﯿ ﺰ ﻣ ﺐﺟﻮ ﻒﯿﻌﻀﺗ

ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ دﺮﮑﻠﻤﻋ ﻣ

ﯽ دﻮﺷ

، ﺮﺑﺎﻨﺑ ﻦﯾا ﻦﺘﻓﺎﯾ شور ﺎﻫ ﯽﯾ ﻢﯿﻧاﻮﺘﺑ ﻪﮐ ﻪﺑ

ﺳو ﯿﻠ ﮥ نآ ﻠﻤﻋ ﺖﯾﻮﻘﺗ ﻪﺑ ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ دﺮﮑ

و ﺑ ﮑﻠﻤﻋ دﻮﺒﻬ ﯽﺷزرو دﺮ

نارﺎﮑﺷزرو ﻢﯿﻨﮐ ﮏﻤﮐ

، يروﺮﺿ و ﻢﻬﻣ ﺖﺳا

، ﻦﯾﺪﺑ زا فﺪﻫ رﻮﻈﻨﻣ ﻘﺤﺗ

ﯿ ﻖ ﺮﺿﺎﺣ ﻦﯿﯿﻌﺗ ﺛﺄﺗ ﯿﺮ فﺮﺼﻣ راد ﻞﻤﮑﻣ ﭼﯿ

ﻦ ﻪﺑ ناﻮﻨﻋ هﺎﯿﮔ ﮏﯾ

ﯽﯾوراد ﯽﺑ ﻪﺿرﺎﻋ ﺮﺑ ﺦﺳﺎﭘ ﺎﻫ ي ﻢﺘﺴﯿﺳ اﯾ ﻨﻤ ﯽ لﺎﻌﻓ ناﺮﺴﭘ رو

رﺎﮑﺷز ﯽﭘ رد ﯾ ﮏ ﻟﺎﻌﻓ ﻪﺴﻠﺟ ﯿ

ﺖ ﺷزرو ﯽ ﻣاو ﺪﻧﺎ ه زﺎﺳ .دﻮﺑ

شور ﺶﻫوﮋﭘ ﯽﺳﺎﻨﺷ

ﺶﻫوﮋﭘ عﻮﻧ زا ﺮﺿﺎﺣ ﻪﻤﯿﻧ

ﺑﺮﺠﺗ ﯽ .ﺖﺳا ﯽﻧﺎﺴﻧا لﺪﻣ ﺎﺑ ﮥﻌﻣﺎﺟ

يرﺎﻣآ ﻖﯿﻘﺤﺗ ، مﺎﻤﺗ لﺎﻌﻓ ناﺮﺴﭘ ﻮﺠﺸﻧاد

ي ﻮﻀﻋ زا ﯽﮑﯾ ﺗﯿ ﻢ ﺎﻫ ي ﯽﺷزرو

ﺪﻧدﻮﺑ زاﺮﯿﺷ هﺎﮕﺸﻧاد .

ﺐﻠﻃواد ﺮﺴﭘ نارﺎﮑﺷزرو ﻦﯿﺑ زا 12

ﻢﻟﺎﺳ ﯽﻧدﻮﻣزآ ﻦﺳ)

93 /1

± 22

،لﺎﺳ ﺪﻗ 56 /6

± 56 / 172 ﯽﺘﻧﺎﺳ

،ﺮﺘﻣ نزو

54 /

±56/6611 ﮐ ﯿ مﺮﮔﻮﻠ ( ﺎﺑ ﮥﻘﺑﺎﺳ ﻞﻗاﺪﺣ ﯾ ﮏ لﺎﺳ ﻢﻈﻨﻣ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ )

ﻪﺴﻠﺟ ﻪﺳ ( ﻪﺘﻔﻫ رد

ﻪﺑ ناﻮﻨﻋ ﮥﻧﻮﻤﻧ ﺪﻧﺪﺷ بﺎﺨﺘﻧا يرﺎﻣآ .

ود

زآ زا ﺮﻔﻧ ﻧدﻮﻣزآ ﯽ ﺎﻫ ﻪﺑ ﺖﻠﻋ ﺳآ ﯿ ﺐ دﯾ ﮔﺪ ﯽ زا ﮥﻣادا داد فاﺮﺼﻧا ﻖﯿﻘﺤﺗ .ﺪﻧ

بﺎﺨﺘﻧا زا ﺲﭘ ﻧدﻮﻣزآ

ﯽ ﺎﻫ ﻃ ، ﯽ ﮥﺴﻠﺟ ﻬﯿﺟﻮﺗ ﻓﺮﻌﻣ ﻪﺑ ﺎﻬﻧآ ﺎﺑ ﯽ ﯽ

و ﺪﺷ ﻪﺘﺧادﺮﭘ نﻮﻣزآ مﺎﺠﻧا ﻞﺣاﺮﻣ و رﺎﮐ شور زا

ﻧدﻮﻣزآ ﯽ ﺎﻫ رﺎﮑﻤﻫ مﺮﻓ ﺎﺗ ﺪﺷ ﻪﺘﺳاﻮﺧ ي

و ﻣﺎﻨﺸﺳﺮﭘ ﮥ وﺎﺣ ي ﺼﺨﺷ تﺎﻋﻼﻃا ﯽ

ﻖﺑاﻮﺳ و

ﮑﺷﺰﭘ ﯽ - ﺷزرو ﯽ

، ﻤﮑﺗ ار ﯿ ﻞ ﺪﻨﻨﮐ ﺎﺑ و ﺎﻌﻣ مﺎﺠﻧا ﯾ تﺎﻨ ﮑﺷﺰﭘ ﯽ ﻼﺘﺑا مﺪﻋ و ﻞﻣﺎﮐ ﺖﻣﻼﺳ زا ي

ﻪﺑ نﺎﻧآ ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﻧﻮﻔﻋ ﯽ ﻏ و ﯿﺮ ه نﺎﻨﯿﻤﻃا

.ﺪﺷ ﻞﺻﺎﺣ

راﺰﺑا

لﺎﮑﯿﺠﻣ كرﺎﻣ ﺎﺑ ﻞﯿﻣدﺮﺗ زا ﯽﮔﺪﻧﺎﻣاو ﺪﺣ ﺎﺗ سوﺮﺑ نﻮﻣزآ مﺎﺠﻧا ياﺮﺑ 1

ﺪﺷ هدﺎﻔﺘﺳا ﻦﯿﭼ ﺖﺧﺎﺳ .

نزو و ﺪﻗ ﻧدﻮﻣزآ

ﯽ ﺎﻫ يراﻮﯾد ﺞﻨﺳﺪﻗ ﺎﺑ

لﺪﻣ) 85 ﺖﻗد ﺎﺑ ناﺮﯾا ﺪﻨﻬﺳ ﺖﮐﺮﺷ ﺖﺧﺎﺳ bsr

5/

0 ﺘﻧﺎﺳ ﯽ ﺮﺘﻣ لﺪﻣ) ﯽﮑﯾﺮﺘﮑﻟا يوزاﺮﺗ و ( 85

ﺖﮐﺮﺷ ﺖﺧﺎﺳbsr

ا ﺪﻨﻬﺳ ﯾ ناﺮ ﺎﺑ ﺖﻗد

1/

0 (مﺮﮔﻮﻠﯿﮐ هزاﺪﻧا

ﮔﯿ ﺮ ي ﺪﺷ ﺺﺧﺎﺷ ،ﺪﻗ روﺬﺠﻣ ﺮﺑ ﻢﯿﺴﻘﺗ نزو لﻮﻣﺮﻓ زا هدﺎﻔﺘﺳا ﺎﺑ و ةدﻮﺗ

) ﯽﻧﺪﺑ .ﺪﺷ ﻪﺒﺳﺎﺤﻣ (BMI

ﻦﯿﻨﭽﻤﻫ اﺮﺑ

ي

1. Cinnamomum

2. Nuclear factor kappa light chain enhancer of activated B lymphocytes (NF-kB)

(6)

هزاﺪﻧا ﮔﯿ ﺮ ي ﭼراد ﻞﻤﮑﻣ ﯿ

ﻦ وزاﺮﺗ زا ي د ﯾ ﺠ ﯿ لﺎﺘ ﻣ لﺎﻨﺸﻓوﺮﭘ ﯿﻨ

ﯽ ﭼ ﺖﺧﺎﺳ ﯿ ﻦ اﺮﺑ و ي ﻦﯿﯿﻌﺗ ﺎﻫرﻮﺘﮐﺎﻓ ي ﺳ ﯿ ﻢﺘﺴ اﯾ ﻨﻤ ﯽ ﺮﻈﻧدرﻮﻣ ﺳﻮﻧﻮﻣ) ﯿ

،ﺖ

ﻓوﺮﺗﻮﻧ ﯿ ﻞ و ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ( هﺎﮕﺘﺳد زا

sysmex

كرﺎﻣ ﺎﺑ

XS-800i

ﺎﮑﯾﺮﻣآ ﺖﺧﺎﺳ و

ﻣﯿ پﻮﮑﺳوﺮﮑ .ﺪﺷ هدﺎﻔﺘﺳا

ﻖﯿﻘﺤﺗ ياﺮﺟا ﺪﻧور

ﻘﺤﺗ ﯿ ﻖ شور ﻪﺑ ﺮﺿﺎﺣ ﯾ

ﮏ ﻮﺳ رﻮﮐ مﺎﺠﻧا ،ﺖﻓﺮﮔ ﻦﯾﺪﺑ ﻪﮐ ﻪﻧﻮﮔ ﻧدﻮﻣزآ ﯽ ﺎﻫ ﻞﻤﮑﻣ ﺎﯾ ﺎﻤﻧوراد فﺮﺼﻣ زا ﺑ

ﯽ عﻼﻃا .ﺪﻧدﻮﺑ ﻪﺑ رﻮﻈﻨﻣ لﺮﺘﻨﮐ ﺛﺄﺗ ﯿﺮ

يﺮﯿﮔدﺎﯾ نﻮﻣزآ ﻊﻃﺎﻘﺘﻣ ﻞﮑﺷ ﻪﺑ هوﺮﮔ ﮏﯾ ﺎﺑ

10 هﺮﻔﻧ ) ﻢﯿﺴﻘﺗ ﻧدﻮﻣزآ ﯽ ﺎﻫ ي ﺖﻤﺴﻗ ود ﻪﺑ 5

هﺮﻔﻧ مﺎﺠﻧا ( ﺖﻓﺮﮔ ﻪﺑ ﻪﻠﺣﺮﻣ ود رد ﯽﻧدﻮﻣزآ .

ﻪﺘﻔﻫ ﮏﯾ تﺪﻣ و ﺎﻤﻧوراد

.دﺮﮐ فﺮﺼﻣ ﻦﯿﭼراد ﻞﻤﮑﻣ رد

ﮥﻠﺣﺮﻣ لوا ، ﻪﺑ ترﻮﺻ ﮏﯾ ﻪﻧازور لﻮﺴﭙﮐ دﺪﻋ

500 ﻣ ﯿﻠ ﯽ ﻣﺮﮔ ﯽ ﻪﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ

لﻮﺴﭙﮐ و لوا ﯽﻧدﻮﻣزآ ﺞﻨﭘ وﺎﺣ

ي درآ ﻪﺑ ناﻮﻨﻋ ﺎﻤﻧوراد ﻪﺑ ﺞﻨﭘ زآ ﻧدﻮﻣ ﯽ مود ﺪﺷ هداد و ﻪﻧﻮﻤﻧ ﺎﻫ ي ﻧﻮﺧ ﯽ ﺖﺑﻮﻧ ود رد ﺶﯿﭘ

ﻗد هدﺰﻧﺎﭘ و ﯿ

ﻪﻘ

ﺲﭘ نﻮﻣزآ زا سوﺮﺑ

سﺎﻨﺷرﺎﮐ ﻂﺳﻮﺗ نﻮﺧ

ﮔﯿ ﺮ ي ﺪﯾرو زا ﺶﯿﭘ راﺪﻘﻣ ﻪﺑ ﯽﯾوزﺎﺑ 10

ﺳ ﯽ ﺳ ﯽ ﻊﻤﺟ روآ ي ﺪﺷ . ﺲﭙﺳ ﺖﯾﺎﻋر ﺎﺑ ﻞﮑﺗوﺮﭘ

ﺎﻫ ي

ﻪﻃﻮﺑﺮﻣ ﻪﺑ رﻮﻈﻨﻣ ﺰﺠﺗ ﯾﻪ ﻠﺤﺗو ﯿ ﻞ ﺎﻣزآ ﻪﺑ ﯾ هﺎﮕﺸ زاﺮﯿﺷ يزﺎﻤﻧ نﺎﺘﺳرﺎﻤﯿﺑ ﺪﻧﺪﺷ ﻞﻘﺘﻨﻣ

. رد ﮥﻠﺣﺮﻣ مود

، دﺪﻋ ﮏﯾ ﻪﻧازور لﻮﺴﭙﮐ

500

ﻣﯿ ﻠ ﯽ ﻣﺮﮔ ﯽ وﺎﺣ ي ﭼراد ردﻮﭘ ﯿ ﻦ مود ﯽﻧدﻮﻣزآ ﺞﻨﭘ ﻪﺑ و

لﻮﺴﭙﮐ 500 ﻣ ﯿﻠ ﯽ ﻣﺮﮔ ﯽ درآ يوﺎﺣ ﻪﺑ

ناﻮﻨﻋ لوا ﯽﻧدﻮﻣزآ ﺞﻨﭘ ﻪﺑ ﺎﻤﻧوراد ﺪﺷ هداد

ﺲﮑﻋﺮﺑ) ﮥﻠﺣﺮﻣ

(ﻖﯿﻘﺤﺗ لوا و

ﻪﻧﻮﻤﻧ ﺎﻫ ي ﻧﻮﺧ ﯽ ﺎﻬﻧآ ﻗد هدﺰﻧﺎﭘ و ﻞﺒﻗ ﺖﺑﻮﻧ ود رد ﯿ

ﻪﻘ ﺲﭘ نﻮﻣزآ زا سوﺮﺑ

ﮐ ﻂﺳﻮﺗ سﺎﻨﺷرﺎ نﻮﺧ ﮔﯿ ﺮ ي

ﻊﻤﺟ روآ ي و ﺖﻬﺟ ﺰﺠﺗ ﯾﻪ ﻠﺤﺗو ﯿ ﻞ ﺎﻣزآ ﻪﺑ ﯾ هﺎﮕﺸ ﺪﻧﺪﺷ ﻞﻘﺘﻨﻣ .

ﻧا زور ود ﺮﻫ رد مﺎﺠ

ﻘﺤﺗ ﯿ ﻖ ﻌﺿو رد) ﯿ ﺖ ﻪﺑ (ﻞﻤﮑﻣ و ﺎﻤﻧوراد ﻤﻫ

ﮥ ﻧدﻮﻣزآ ﯽ ﺎﻫ

ﯾ ﮏ ﺖﻋﺎﺳ ﺶﯿﭘ نﻮﻣزآ زا ﻧﺎﺤﺒﺻ

ﮥ ﮐﺮﺘﺸﻣ ﯽ و ﺪﺷ هداد ﻪﺑ

رﻮﻈﻨﻣ ﻞﻣاﻮﻋ لﺮﺘﻨﮐ ﺬﻐﺗ

ﯾﻪ ا ي زا ﻧدﻮﻣزآ ﯽ ﺎﻫ ﻘﺤﺗ تﺪﻣ رد ﺎﺗ ﺪﺷ ﻪﺘﺳاﻮﺧ ﯿ

ﻖ زا

اﺬﻏ ي درﻮﻣ رد ﻪﮐ هﺎﮕﺸﻧاد ﻤﻫ

ﮥ ﻧدﻮﻣزآ ﯽ ﺎﻫ ﯾ نﺎﺴﮑ دﻮﺑ

، ﺪﻨﻨﮐ هدﺎﻔﺘﺳا فﺮﺼﻣ زا ﻖﯿﻘﺤﺗ تﺪﻣ لﻮﻃ رد و

ﻞﻤﮑﻣ ﺎﻫ ي

،ﯽﯾاﺬﻏ و تﺎﯿﻧﺎﺧد

ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ دﺮﮑﻠﻤﻋ ﺮﺑ ﻪﮐ ﯽﯾﺎﻫوراد ﺛﺄﺗ

ﯿﺮ ﻣ ﯽ دراﺬﮔ

، ﺪﻨﻨﮐ يراددﻮﺧ .

ﻖﯿﻘﺤﺗ ﻦﯾا رد ﯽﺷزرو ﻞﮑﺗوﺮﭘ ﯽﻧدﻮﻣزآ ﺮﻫ ﻪﮐ دﻮﺑ ترﻮﺻ ﻦﯾا ﻪﺑ

يور ﺐﯿﺷ ﺎﺑ ﻞﯿﻣدﺮﺗ وا

ﮥﯿﻟ 10 ﺖﻋﺮﺳ و ﻪﺟرد 2/

7 ﺮﺘﻣﻮﻠﯿﮐ ﺖﻋﺎﺳ رد ﺖﯿﻟﺎﻌﻓ ﻪﺑ عوﺮﺷ

ﻣ ﯽ دﺮﮐ ﻪﻘﯿﻗد ﺮﻫ رد و 1

ﺪﺻرد ﻪﺑ هﺎﮕﺘﺳد ﺐﯿﺷ

هدوﺰﻓا ﻣ ﯽ ﺪﺷ ﻪﺑ دﺮﻓ ﻪﮑﻨﯾا ﺎﺗ 85

،ﻪﻠﺣﺮﻣ ﻦﯾا ﻪﺑ نﺪﯿﺳر زا ﺲﭘ .ﺪﺳﺮﺑ دﻮﺧ ﺐﻠﻗ نﺎﺑﺮﺿ ﺪﺻرد 6

ﻆﻔﺣ ﻂﯾاﺮﺷ ﻪﻘﯿﻗد ﻣ

ﯽ ﺪﺷ زا ﺲﭘ و 6

دﻮﺑ هﺪﯿﺳﺮﻧ ﯽﮔﺪﻧﺎﻣاو ﺪﺣ ﻪﺑ دﺮﻓ ﻪﭽﻧﺎﻨﭼ ،ﻪﻘﯿﻗد ﻪﻘﯿﻗد ﺮﻫ يازا ﻪﺑ هرﺎﺑود ،

1 ﺎﺗ ﺖﻓﺎﯾ ﺶﯾاﺰﻓا ﺐﯿﺷ ﺪﺻرد ﯽﻧﺎﻣز

ﯽﮔﺪﻧﺎﻣاو ﺪﺣ ﻪﺑ دﺮﻓ ﻪﮐ

ﺪﺳﺮﺑ ) 19 (

.

يرﺎﻣآ شور

اﺮﺑ ي ﺰﺠﺗ ﯾﻪ ﻠﺤﺗو ﯿ ﻞ ﯾ ﻪﺘﻓﺎ ﺎﻫ ي زا ﺶﻫوﮋﭘ مﺮﻧ

راﺰﻓا رﺎﻣآ ي ﺨﺴﻧ SPSS ﮥ 18 زا .ﺪﺷ هدﺎﻔﺘﺳا نﻮﻣزآ

ﺎﻫ ي رﺎﻣآ ي ﺻﻮﺗ ﯿﻔ ﯽ

، ﮐ ﻮ فوﺮﮔﻮﻤﻟ -

ﻤﺳا ﯿ فﻮﻧﺮ اﺮﺑ ي ﺳرﺮﺑ ﯽ ﺒﻃ ﯿﻌ ﯽ ندﻮﺑ ﯾ ﻪﺘﻓﺎ و اﺮﺑ ي ﺨﺳﺎﭘ ﯽﯾﻮﮕ ﻪﺑ ﺶﺳﺮﭘ ﯽﻣﺎﻤﺗ يﺎﻫ

ﻘﺤﺗ ﯿ ﻖ زا نﻮﻣزآ ﺢﻄﺳ ،ﺪﺷ هدﺎﻔﺘﺳا ﻪﺘﺴﺒﻤﻫ t

رادﺎﻨﻌﻣ ي

05 / 0 P<

ﺮﮔ ﺮﻈﻧ رد ﻪﺘﻓ

.ﺪﺷ

ﻪﺘﻓﺎﯾ ﺶﻫوﮋﭘ يﺎﻫ

لوﺪﺟ رد 1 رﺎﯿﻌﻣ فاﺮﺤﻧا و ﻦﯿﮕﻧﺎﯿﻣ وﯾ

ﮔﮋ ﯽ ﺎﻫ ي يدﺮﻓ ﻧدﻮﻣزآ ﯽ ﺎﻫ

،ﻦﺳ ﻞﻣﺎﺷ

،ﺪﻗ ﺺﺧﺎﺷ و نزو ةدﻮﺗ

ﯽﻧﺪﺑ ﻪﺑ .ﺖﺳا هﺪﺷ ﯽﻓﺮﻌﻣ ﺐﯿﺗﺮﺗ

لوﺪﺟ 1 . ﻊﯾزﻮﺗ ﺺﺧﺎﺷ ﺎﻫ ي ﯽﻔﯿﺻﻮﺗ رﺎﻣآ وﯾ

ﮔﮋ ﯽ ﺎﻫ ي يدﺮﻓ ) لﺎﻌﻓ ناﺮﺴﭘ 10

(n=

داﺪﻌﺗ ﻦﺳ

ﺪﻗ نزو

) ﯽﻧﺪﺑ ةدﻮﺗ ﺺﺧﺎﺷ ( BMI

10 93

/1 22±

569 /6 56±

/ 172 54

/ 11 56±

34 /1 2/±

21

لوﺪﺟ رد 2 زا ﻞﺻﺎﺣ ﺞﯾﺎﺘﻧ ﺛﺄﺗ

ﯿﺮ ﺮﺑ ﺎﻤﻧوراد ﻞﻤﮑﻣ فﺮﺼﻣ و ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ درﻮﻣ ﯽﻨﻤﯾا ﻢﺘﺴﯿﺳ يﺎﻫرﻮﺘﮐﺎﻓ

ﺶﯿﭘ ﯽﺳرﺮﺑ و

15

ﻗد ﻪﻘﯿ ﺲﭘ سوﺮﺑ نﻮﻣزآ زا .ﺖﺳا هﺪﺷ ﻪﺋارا

(7)

ﺛﺄﺗ ﯿ ﺮ اد ﭼر ﯿ ﻦ ﺦﺳﺎﭘ ﺮﺑ ﺎﻫ ي اﯾ ﻨﻤ ﯽ ﯽﭘ رد ﯾ ﮏ ﻟﺎﻌﻓ ﻪﺴﻠﺟ ﯿ

ﺖ ﺷزرو ﯽ هﺪﻧﺎﻣاو لﺎﻌﻓ ناﺮﺴﭘ رد زﺎﺳ

23

لوﺪﺟ 2 . ﺛﺄﺗ ﯿ ﺮ ﯽﻨﻤﯾا ﻞﻣاﻮﻋ ﺮﺑ ﺎﻤﻧوراد ﻞﻤﮑﻣ فﺮﺼﻣ و ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ رﺎﯿﻌﻣ فاﺮﺤﻧا)

(ﻦﯿﮕﻧﺎﯿﻣ

ﺎﻫﺮﯿﻐﺘﻣ ﺖﯿﻌﺿو

ﺶﯿﭘ نﻮﻣزآ ﺲﭘ

نﻮﻣزآ

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﺖﯿﺳﻮﻔﻨﻟ ﻞﻤﮑﻣ

998 /4 1/ ± 247 39

/4 6± / 41

ﺎﻤﻧوراد 285

/6 8/ ± 31 907

/5 3± / 42

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﺖﯿﺳﻮﻧﻮﻣ ﻞﻤﮑﻣ

135 /1 2± / 054 2

/1 2±

/1 1/ ± 2 211

/2 3±

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﻞﯿﻓوﺮﺗﻮﻧ ﻞﻤﮑﻣ

245 /5 8/ ± 521 56

/3 8± / 53

/5 3/ ± 64 535

/6 6± / 52

ﺖﯿﺳﻮﻔﻨﻟ ﻪﺑ ﻞﯿﻓوﺮﺗﻮﻧ (ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﻞﻤﮑﻣ

319 / 489 ± / 1 234

/ 314± / 1

/ 112 ± / 319 2

/ 281± / 1

لوﺪﺟ رد 3

زا ﻞﺻﺎﺣ ﺞﯾﺎﺘﻧ ﺛﺄﺗ

ﯿﺮ ﯽﻨﻤﯾا ﻞﻣاﻮﻋ ﯽﻣﺮﺳ تاﺮﯿﯿﻐﺗ ﺮﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ درﻮﻣ

ﯽﺳرﺮﺑ ﺖﺳا هﺪﺷ ﻪﺋارا .

لوﺪﺟ 3 . ﺛﺄﺗ ﯿ ﺮ ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﺑ

ﯽﻨﻤﯾا ﻞﻣاﻮﻋ ﯽﻣﺮﺳ تاﺮﯿﯿﻐﺗ ﺮ رﺎﯿﻌﻣ فاﺮﺤﻧا)

(ﻦﯿﮕﻧﺎﯿﻣ

ﺎﻫﺮﯿﻐﺘﻣ ﺖﯿﻌﺿو

تاﺮﯿﯿﻐﺗ Df

t P

ﻟ (ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﺖﯿﺳﻮﻔﻨ ﻞﻤﮑﻣ

273

±2/ 5 / 9 2

836 / 2 02

/

0 10/ 5±8/263 ﺎﻤﻧوراد

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﺖﯿﺳﻮﻧﻮﻣ ﻞﻤﮑﻣ

91 /

±0 2 / 9 0

557 / 1 154

/

0 /09± /079 ﺎﻤﻧوراد

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﻞﯿﻓوﺮﺗﻮﻧ ﻞﻤﮑﻣ

339

±3/ 9 3

978 / 2 15

/

0 11/ 7±7/916 ﺎﻤﻧوراد

ﺑ ﻞﯿﻓوﺮﺗﻮﻧ ﺖﯿﺳﻮﻔﻨﻟ ﻪ

(ﺮﺘﯿﻟوﺮﮑﯿﻣ ﻪﺑ ﺪﺻرد) ﻞﻤﮑﻣ

167 /

±0 174 / 9 0

141 / 3 012

/

0 0/83±/ 588 ﺎﻤﻧوراد

ﺛﺄﺗ ﯿ ﺮ فﺮﺼﻣ ﺖﯿﺳﻮﻔﻨﻟ تاﺮﯿﯿﻐﺗ ﺮﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ

رادﻮﻤﻧ) ﺞﯾﺎﺘﻧ 1

داد نﺎﺸﻧ ( ﻐﺗ

ﯿﯿ تاﺮ داﺪﻌﺗ ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ي مﺮﺳ ﺲﭘ و ﺶﯿﭘ نﻮﻣزآ زا

سوﺮﺑ رد ﻌﺿو ﯿ ﺖ ﺎﻫ ي ﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﯿ

ﻦ و د ﺎﻤﻧورا

ﺎﺑ ﯾ ﺪﮑ ﯾ ﺮﮕ رادﺎﻨﻌﻣ توﺎﻔﺗ ي

ﻧراد ﺪ ) 02 / 0 (P=

ا ﻪﮐ ، ﯾ ﻦ ﺎﺘﻧ ﯾ ﺞ ﺎﺑ ﺎﻘﻣ ﯾ ﺴ ﮥ لوﺪﺟ 2 نﺎﺸﻧ ﻣ ﯽ ﺪﻫد ا ﻪﭼﺮﮔ ﯽﭘ رد هﺪﻧﺎﻣاو ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ زﺎﺳ

رد

ﺮﻫ ﻌﺿو ود ﯿ ﺖ ﺎﻤﻧوراد و ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﺳﻮﻔﻨﻟ

ﯿ ﺖ ﺎﻫ ي اﺰﻓا مﺮﺳ ﯾ ﺶ ﯾ ﻪﺘﻓﺎ

، ﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﺎﻣا ﯿ

ﻦ ﺐﺟﻮﻣ ﺷ ﺮﺘﻤﮐ ﻣ نﺪ ﯿ ناﺰ

ﻐﺗ ﯿﯿ تاﺮ ﯽﺸﯾاﺰﻓا ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ ﺖﺳا هﺪﺷ .

(8)

رادﻮﻤﻧ 1 . ﮥﺴﯾﺎﻘﻣ تاﺮﯿﯿﻐﺗ ﺲﭘ و ﺶﯿﭘ نﻮﻣزآ زا

) ﺖﯿﺳﻮﻔﻨﻟ ( ﻒﻠﺘﺨﻣ ﻞﺣاﺮﻣ رد ﻖﯿﻘﺤﺗ

* ﮥﻧﺎﺸﻧ ﻪﺑ ﺖﺒﺴﻧ رادﺎﻨﻌﻣ توﺎﻔﺗ ﮥﻠﺣﺮﻣ

ﺎﻤﻧوراد ) 05 / 0 P<

(

ﺛﺄﺗ ﯿ ﺮ فﺮﺼﻣ ﺖﯿﺳﻮﻧﻮﻣ تاﺮﯿﯿﻐﺗ ﺮﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ

ﺞﯾﺎﺘﻧ رادﻮﻤﻧ) 2 داد نﺎﺸﻧ ( ﻐﺗ

ﯿﯿ تاﺮ ﺳﻮﻧﻮﻣ داﺪﻌﺗ ﯿ

ﺖ ﺎﻫ ي مﺮﺳ ﺲﭘ و ﺶﯿﭘ رد نﻮﻣزآ زا

ﻌﺿو ﯿ ﺖ ﺎﻫ ي ﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﯿ

ﻦ ﺎﺑ ﺎﻤﻧوراد و

ﯾ ﺪﮑ ﯾ ﺮﮕ رادﺎﻨﻌﻣ توﺎﻔﺗ ي

ﺪﻧراﺪﻧ

) 154 /0

.(P=

رادﻮﻤﻧ 2 . ﮥﺴﯾﺎﻘﻣ تاﺮﯿﯿﻐﺗ ﺲﭘ و ﺶﯿﭘ ) نﻮﻣزآ زا

ﺖﯿﺳﻮﻧﻮﻣ ( ﻒﻠﺘﺨﻣ ﻞﺣاﺮﻣ رد ﻖﯿﻘﺤﺗ

&

ﮥﻧﺎﺸﻧ ﻪﺑ ﺖﺒﺴﻧ ندﻮﺒﻧ رادﺎﻨﻌﻣ ﮥﻠﺣﺮﻣ

) ﺎﻤﻧوراد 05 / 0 P>

(

(9)

ﺛﺄﺗ ﯿ ﺮ اد ﭼر ﯿ ﻦ ﺦﺳﺎﭘ ﺮﺑ ﺎﻫ ي اﯾ ﻨﻤ ﯽ ﯽﭘ رد ﯾ ﮏ ﻟﺎﻌﻓ ﻪﺴﻠﺟ ﯿ ﺖ ﺷزرو ﯽ هﺪﻧﺎﻣاو لﺎﻌﻓ ناﺮﺴﭘ رد زﺎﺳ

25

ﺛﺄﺗ ﯿ ﺮ فﺮﺼﻣ ﻞﯿﻓوﺮﺗﻮﻧ تاﺮﯿﯿﻐﺗ ﺮﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ

ﯿﯿ تاﺮ ﻓوﺮﺗﻮﻧ داﺪﻌﺗ ﯿ

ﻞ ﺎﻫ ي مﺮﺳ ﺲﭘ و ﺶﯿﭘ رد نﻮﻣزآ زا

ﻌﺿو ﯿ ﺖ ﺎﻫ ي ﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﯿ

ﻦ و د ﺎﺑ ﺎﻤﻧورا

ﯾ ﺪﮑ ﯾ ﺮﮕ رادﺎﻨﻌﻣ توﺎﻔﺗ ي

ﻧراد ﺪ ) 015 /0 (،P=

ﯾا ﻦ ﺎﺘﻧ ﯾ ﺞ ﺎﺑ ﺎﻘﻣ ﯾ ﺴ ﮥ لوﺪﺟ 2 نﺎﺸﻧ ﻣ ﯽ ﺪﻫد ﻪﭼﺮﮔا ﻪﮐ رد

ﯽﭘ ﯾ ﮏ ﻪﺴﻠﺟ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ

هﺪﻧﺎﻣاو زﺎﺳ ﻓوﺮﺗﻮﻧ ﯿ ﻞ ﺎﻫ ي ﻌﺿو ودﺮﻫ رد مﺮﺳ ﯿ

ﺖ فﺮﺼﻣ ﻞﻤﮑﻣ ﻦﯿﭼراد ﺎﻤﻧوراد و ﺶﻫﺎﮐ

ﯾ ﻪﺘﻓﺎ

، ﮑﻣ فﺮﺼﻣ ﺎﻣا ﭼراد ﻞﻤ

ﯿ ﻦ ﻣ ﺐﺟﻮ ﺮﺘﻤﮐ

ﻐﺗ نﺪﺷ ﯿﯿ تاﺮ ﯽﺸﻫﺎﮐ ﻓوﺮﺗﻮﻧ ﯿ ﻞ ﺎﻫ ﺖﺳا هﺪﺷ .

.

رادﻮﻤﻧ 3 . ﮥﺴﯾﺎﻘﻣ تاﺮﯿﯿﻐﺗ ﺲﭘ و ﺶﯿﭘ ﯿﻓوﺮﺗﻮﻧ) نﻮﻣزآ زا

ﻖﯿﻘﺤﺗ ﻒﻠﺘﺨﻣ ﻞﺣاﺮﻣ رد (ﻞ

* ﮥﻧﺎﺸﻧ ﻪﺑ ﺖﺒﺴﻧ رادﺎﻨﻌﻣ توﺎﻔﺗ ﮥﻠﺣﺮﻣ

) ﺎﻤﻧوراد 05 / 0 P<

(

ﺛﺄﺗ ﯿ ﺮ فﺮﺼﻣ تاﺮﯿﯿﻐﺗ ﺮﺑ ﻦﯿﭼراد ﻞﻤﮑﻣ ﺖﺒﺴﻧ

ﻞﯿﻓوﺮﺗﻮﻧ ﺖﯿﺳﻮﻔﻨﻟ ﻪﺑ

ﯿﯿ تاﺮ ﻓﺮﺗﻮﻧ ﺖﺒﺴﻧ ﯿ

ﻞ ﺎﻫ ﻪﺑ ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ مﺮﺳ ﺲﭘ و ﺶﯿﭘ رد نﻮﻣزآ زا

و ﻌﺿ ﯿ ﺖ ﺎﻫ ي ﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﯿ

ﻦ و

راد ﺎﺑ ﺎﻤﻧو ﯾ ﺪﮑ ﯾ ﺮﮕ توﺎﻔﺗ ﺪﻧراد يرادﺎﻨﻌﻣ )

012 /0 ،(P=

اﯾ ﻦ ﺎﺘﻧ ﯾ ﺞ رد ﺎﻘﻣ ﯾ ﻪﺴ ﺎﺘﻧ ﺎﺑ ﯾ ﺞ لوﺪﺟ 2 نﺎﺸﻧ ﻣ ﯽ ﺪﻫد ا ﻪﭼﺮﮔ ﻪﺑ لﺎﺒﻧد ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ

هﺪﻧﺎﻣاو زﺎﺳ ﺮﻫ رد ﻌﺿو ود ﯿ ﺖ ﺎﻤﻧوراد و ﻦﯿﭼراد ﻞﻤﮑﻣ فﺮﺼﻣ ﻓﺮﺗﻮﻧ ﺖﺒﺴﻧ

ﯿ ﻞ ﺎﻫ ﻪﺑ ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ

،ﻪﺘﻓﺎﯾ ﺶﻫﺎﮐ ﺮﺼﻣ ﺎﻣا

راد ﻞﻤﮑﻣ ف ﭼﯿ

ﻦ

ﺐﺟﻮﻣ نﺪﺷ ﺮﺘﻤﮐ ﻐﺗ

ﯽﺸﻫﺎﮐ تاﺮﯿﯿ ﻓﺮﺗﻮﻧ ﺖﺒﺴﻧ

ﯿ ﻞ ﺎﻫ ﻪﺑ ﺳﻮﻔﻨﻟ ﯿ ﺖ ﺎﻫ .ﺖﺳا هﺪﺷ مﺮﺳ