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ABSTRAK
Latar Belakang: MACE merupakan suatu komplikasi mayor kardiovaskular yang masih sering dijumpai pada pasien IMA walaupun pasien telah mendapat penanganan yang adekuat. Hiponatremi saat admisi dapat menjadi suatu prediksi awal terhadap kejadian MACE pada pasien IMA.
Tujuan: Mengetahui hubungan antara kadar natrium dengan kejadian MACE pada pasien IMA di RSUP Haji Adam Malik Medan.
Metode: Penelitian analitik ini menggunakan desain cross-sectional dengan populasi pasien IMA yang dirawat di RSUP Haji Adam Malik periode 2014. Sebanyak 90 sampel diambil secara consecutive sampling.
Hasil: Dari hasil penelitian, didapatkan bahwa 65,6% laki - laki mengalami kejadian infark miokard akut. Kemudian, IMA paling banyak terjadi pada usia 51 - 60 tahun (41,1%). Melalui analisis univariat, didapati 41,1% pasien datang dengan kondisi hiponatremi dan 61,1% mengalami MACE selama masa perawatan (gagal jantung kongestif (38,95%), aritmia (38,95%), kematian (11,58%), dan syok kardiogenik (10,52%)). Melalui analisis chi-square, ada hubungan yang signifikan antara hiponatremi dengan kematian (p=0,045), gagal jantung kongestif (p=0,003), aritmia (p=0,012), dan kejadian MACE (p<0,001) pada pasien IMA.
Kesimpulan: Hiponatremi saat admisi merupakan faktor prediktor kuat terhadap kejadian MACE pada pasien IMA.
Kata kunci: Infark miokard akut, hiponatremi, Major Adverse Cardiovascular Event
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ABSTRACT
Introduction : MACE, which is a major complications in cardiovascular
disease, still frequently encountered in AMI patients. Although patients already get a sufficient treatment. Hyponatremia at admission can be used as an early predictor against MACE in AMI patients.
Objective : To know whether the relationship between natrium level and
MACE exists in AMI patients at RSUP Haji Adam Malik Medan.
Methods : This analytical study was done using cross - sectional design in
90 patients from RSUP Haji Adam Malik period 2014. The sample was taken using consecutive sampling.
Results : From research, most of patients is males (65,6%) with age range
between 51 - 60 years (41,1%). From univariate analysis, hyponatremia was found in 41,1% patients and MACE happen in 61,1% patients during treatment (congestive heart failure (38,95%), arrhythmia (38,95%), deaths (11,58%), shock cardiogenic (10,52%)). With chi square test, the data shows that there is a significant relationship between hyponatremia and deaths (p=0,045), congestive heart failure (p=0,003), arrhythmia (p=0,012), and MACE (p<0,001) in AMI patients.
Conclusion : Hyponatremia admission in AMI patients is a strong predictor
against MACE.
Keywords : Acute Myocard Infarct, hyponatremia, Major Adverse Cardiovascular Event
