يژﻮﻟﻮﯾﺰﯿﻓ
ﯽﺷزرو مﻮﻠﻋ رد ﺶﻫوﮋﭘ يﺎﻫ هزﺎﺗ ﯽﻠﻣ ﺶﯾﺎﻤﻫ
ﻪﻟﺎﻘﻣ ناﻮﻨﻋ ﺮﺑ تﺪﻣ ﯽﻧﻻﻮط تﺎﻨﯾﺮﻤﺗﺮﯿﺛﺎﺗ
نﺎﺒﺴﭼ یﺎھ لﻮﮑﻟﻮﻣ رد
کﺮﺤﺗ ﻢﮐ نﺎﻧز قﺎﭼ
ﯽﯾﺎﺑﺎﺑ زﺎﻤﻟﻮﺳ ﯽﻘﯿﻓﻮﺗ ﺮﻐﺻا ،1
هﺎﺘﺳاد ﻪﻧﺎﻤﺳ ،2
،3
-1 ﻪﯿﻣورا هﺎﮕﺸﻧاد ﯽﺷزرو يژﻮﻟﻮﯾﺰﯿﻓ يﺮﺘﮐد يﻮﺠﺸﻧاد
-2 ﻪﯿﻣورا هﺎﮕﺸﻧاد يژﻮﻟﻮﯾﺰﯿﻓ هوﺮﮔ رﺎﯿﺸﻧاد
-3 ﻪﯿﻣورا هﺎﮕﺸﻧاد ﯽﺷزرو يژﻮﻟﻮﯾﺰﯿﻓ يﺮﺘﮐد يﻮﺠﺸﻧاد
هﺪﯿﮑﭼ
:ﻪﻣﺪﻘﻣ ﯽﻣﻮﻤﻋ بﺎﻬﺘﻟاودراد ﯽﺑﺎﻬﺘﻟا يا ﻪﻨﯿﻣز ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻬﯾرﺎﻤﯿﺑ شﺮﺘﺴﮔﺪﻧا هداد نﺎﺸﻧﺪﻫاﻮﺷ قﺎﭼو نزو ﻪﻓﺎﺿا ياراد داﺮﻓارد هﮋﯾﻮﺑ ﻞﻣاﻮﻋ ﻦﯾاوﺪﻨﮑﯿﻣﺎﻔﯾازوﺮﻠﮑﺳاوﺮﺗآ ﺖﻓﺮﺸﯿﭘرد ﯽﻤﻬﻣ ﺶﻘﻧ(ﮏﯿﻤﺘﺴﯿﺳ)
ﯽﻧﻻﻮﻃﺮﯿﺛﺎﺗ ﯽﺳرﺮﺑ ﺮﺿﺎﺣ ﻖﯿﻘﺤﺗ فﺪﻫ.ﺪﻫد ﺶﯾاﺰﻓاار ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻬﯾرﺎﻤﯿﺑ عﻮﻗوﺮﻄﺧ ﺖﺳا ﻦﮑﻤﻣ تﺪﻣ
تاﺮﯿﯿﻐﺗ ﺮﺑ ﯽﺷزرو ﻢﻈﻨﻣ ﺖﯿﻟﺎﻌﻓ
sVCAM-1 , sICAM-1
.ﺖﺳا كﺮﺤﺗ ﻢﮐ قﺎﭼ نﺎﻧز رد
:يﺮﯿﮔ هزاﺪﻧا شور نز40
ﻢﻟﺎﺳ ﻪﻧﺎﺒﻠﻃواد ترﻮﺻ ﻪﺑ ، رد
ﻖﯿﻘﺤﺗ ﺖﮐﺮﺷ ﺪﻧدﺮﮐ و رﻮﻄﺑ ﯽﻓدﺎﺼﺗ رد
ود هوﺮﮔ
تﺪﻣ ﻪﺑ ﯽﻨﯾﺮﻤﺗ هوﺮﮔ.ﺪﻧﺪﺷ ﻢﯿﺴﻘﺗ ، ﺪﻫﺎﺷ هوﺮﮔ و ، ﯽﻨﯾﺮﻤﺗ ) ﻪﺘﻔﻫ 12
تﺎﻨﯾﺮﻤﺗ (ﻪﺘﻔﻫ رد ﻪﺴﻠﺟ3 يزاﻮﻫ
تﺪﺷ ﺎﺑ ار -75
.ﺪﻧداد مﺎﺠﻧا ﻪﻨﯿﺸﯿﺑ ﺐﻠﻗ نﺎﺑﺮﺿ ﺮﺜﮐاﺪﺣ ﺪﺻرد65 ﯽﻣﺮﺳ ﺢﻄﺳ
sVCAM-1 , sICAM-1
ﯽﻤﯾﺰﻧآ شور ﻪﺑ
Immunosorbent
ﺖﮐﺮﺷ ياﺰﯾﻻا ﺖﯿﮐ زا هدﺎﻔﺘﺳا ﺎﺑ(ﺖﻨﺑروزﻮﻧﻮﻤﯾا)
BMS232
و
BMS232TEN
.ﺪﺷ يﺮﯿﮔ هزاﺪﻧا ﺪﻨﻠﻫ رﻮﺸﮐ هداد ﻞﯿﻠﺤﺗ
يﺎﻔﻟآ يﺎﻄﺧ ﺢﻄﺳ رد ﺎﻫ ﻂﺳﻮﺗ و ﺪﺻرد 5
مﺮﻧ -
راﺰﻓا ﻪﺨﺴﻧSPSS
.ﺪﺷ مﺎﺠﻧا18
ﻪﺘﻓﺎﯾ زا ﺪﻌﺑ داد نﺎﺸﻧ ﺞﯾﺎﺘﻧ:ﺎﻫ ﯽﻨﻌﻣ فﻼﺘﺧا ﻦﯾﺮﻤﺗ ﻪﺘﻔﻫ12
ﺮﯾدﺎﻘﻣ رد يراد
sVCAM-1 , sICAM-1
ﻦﯿﺑ
.ﺪﺷ هﺪﻫﺎﺸﻣ ﺪﻫﺎﺷ و ﯽﻨﯾﺮﻤﺗ هوﺮﮔ
) 05 / 0 P<
. (
ﺚﺤﺑ ﻪﺠﯿﺘﻧو ﻪﺘﻓﺎﯾ :يﺮﯿﮔ يﺎﻫ
ﺶﻫوﮋﭘ ﺮﺿﺎﺣ
نﺎﺸﻧ داد ﯿﻟﺎﻌﻓ ﻢﻈﻨﻣ ﯽﻧﺪﺑ ﺖ ﺐﺟﻮﻣ
ﺶﻫﺎﮐ ﯽﯾﺎﻤﺳﻼﭘ ﺮﯾدﺎﻘﻣ
ﺺﺧﺎﺷ يﺎﻫ ﯽﻗوﺮﻋ ـ ﯽﺒﻠﻗ يازﺮﻄﺧ رد
نﺎﻧز قﺎﭼ ﯽﻣ
،دﻮﺷ ﻦﯾا ﺶﻫﺎﮐ ﯽﻣ ﺪﻧاﻮﺗ رد يﺮﯿﮕﺸﯿﭘ زا
زوﺮﺑ
يرﺎﻤﯿﺑ يﺎﻫ ﯽﺒﻠﻗ ﯽﻗوﺮﻋ ﺮﺛﻮﻣ ﻊﻗاو دﻮﺷ .
تﺎﻨﯾﺮﻤﺗ :يﺪﯿﻠﮐ نﺎﮔژاو يزاﻮﻫ
ﺺﺧﺎﺷ،
قﺎﭼ نﺎﻧز ،ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يازﺮﻄﺧ يﺎﻫ
Effect oflong-termadhesion moleculesin inactive obese women Solmaz babaei1, asghar tofighi2, samaneh dastah1
2phd student of Exercise Physiology, Department of exercise physiology, Urmia University, Urmia, Iran
1Department of exercise physiology, Faculty of Physical Education and sport science, Urmia University, Urmia, Iran
Backgroundand purpose:With the increasing outbreak of obesity and its complications is become important to identify effective methods for reducing cardiovascular risk factors. Therole ofphysical activityina
negativeenergy balance mostresearchershavefocused onthereduction oftheglobalepidemicof womenin society.
The purpose of the present studyof cardiovascular riskindexesin obeseinactivefollowingthephysical activity.
Materials andmethods: Inaquasi-experimentalstudy, 40 obese,inactivewomenwith an age range35-30years,body mass index(BMI)greaterthan 30, thevolunteerswere selected andrandomlydivided intwo the experimental and controlgroups of 20. Experimental groupof 12 weeks(3sessions per week) aerobicexercisewith75- 65percentofmaximum heart ratedid. Cardiovascularprofileofindexvaluesfastingbefore and aftertrainingfor both groups, respectively. Analyze the dataon thelevel ofalphaerror of % 5was performedusing SPSSversion 18.
Results: Results showed thatafter 12 weeks of training,significant differecesinlevels ofsICAM-1andsVCAM-1, betweenexperiment and control groupswere observed.
Discussion and conclusionsThe results ofthis studyshowed thatregular physical activityreducesplasmalevelsof cardiovascular riskfactorsinobese women, this reducedcanbe effectivein preventingcardiovascular disease.
Keywords: Aerobicexercise, indicators ofcardiovascular risk, obese women
ﻪﻣﺪﻘﻣ
رد لﺎﺳ يﺎﻫ ﺮﯿﺧا ﺎﺑ ﺶﯾاﺰﻓا ﺢﻄﺳ هﺎﻓر ﯽﻋﺎﻤﺘﺟا رد
يﺎﻫرﻮﺸﮐ رد
لﺎﺣ
،ﻪﻌﺳﻮﺗ ﮥﻨﻣاد ﯽﻨﺳ زوﺮﺑ يرﺎﻤﯿﺑ يﺎﻫ
ﯽﺒﻠﻗ ﯽﻗوﺮﻋ – ﻪﺑ رﻮﻃ يﺮﯿﮕﻤﺸﭼ ﺶﻫﺎﮐ
ﻪﺘﻓﺎﯾ )ﺖﺳا هزوﺮﻣا .(1 ﯽﯾﺎﺳرﺎﻧ
يﺎﻫ ﺮﻧوﺮﮐ قوﺮﻋ ﻪﺑ
ناﻮﻨﻋ ﯽﮑﯾ
زا يرﺎﻤﯿﺑ يﺎﻫ ﻢﻬﻣ ﻊﻣاﻮﺟ ﯽﺘﻌﻨﺻ و ﺮﺼﻋ ﺮﺿﺎﺣ ﯽﻓﺮﻌﻣ هﺪﺷ ﺖﺳا ﺺﺨﺸﻣ. هﺪﺷ
ﻪﮐ رﻮﺸﮐ رد ﺎﻣ
ﮥﻨﻣاد
زوﺮﺑ ﻦﯾا ﻪﻧﻮﮔ يرﺎﻤﯿﺑ يﺎﻫ ﯽﺷﺎﻧ زا ﯽﺑ ﯽﮐﺮﺤﺗ رد ﻦﯿﺑ نﺎﻧز ﺮﺘﺸﯿﺑ زا نادﺮﻣ ﺖﺳا ًﻻﻮﺻا .
،بﺎﻬﺘﻟا ﺄﺸﻨﻣ
ﺐﻠﻏا يرﺎﻤﯿﺑ يﺎﻫ طﻮﺑﺮﻣ ﻪﺑ هﺎﮕﺘﺳد ﯽﺒﻠﻗ ﯽﻗوﺮﻋ – يرﺎﻤﯿﺑ نآ لﺎﺒﻧد ﻪﺑ و ﯽﻗﺎﭼ عﻮﯿﺷ ﻦﯿﻨﭽﻤﻫ و ﺖﺳا يﺎﻫ
هﺪﻨﯾاﺰﻓ ﺪﺷر ﻪﺘﺷﺬﮔ ﻪﻫد ود رد ﯽﻗﺎﭼ ﻪﺑ طﻮﺑﺮﻣ )ﺖﺳا ﻪﺘﺷاد يا
ﺮﻫ رد نزو ﻪﻓﺎﺿا و ﯽﻗﺎﭼ ﻪﮑﻨﯾا دﻮﺟو ﺎﺑ.(2
ﺖﺳا نآ ﺪﯾﻮﻣ تﺎﻘﯿﻘﺤﺗ ﺖﺳا ﯽﯾﻻﺎﺑ عﻮﯿﺷ ياراد ﯽﺴﻨﺟ ﺮﻫ و ﻦﺳ نﺪﺷ قﺎﭼ ياﺮﺑ يﺮﺘﺸﯿﺑ داﺪﻌﺘﺳا نﺎﻧز
) ﺪﻧراد ﯽﺳرﺮﺑ .(3
هداد نﺎﺸﻧ ﺎﻫ ﻪﯾﺬﻐﺗ يﺎﻫرﺎﺘﻓر رد لﻼﺘﺧا ﺪﻨﻧﺎﻣ ﯽﻠﻣاﻮﻋ ﺪﻧا
ﺖﯿﻟﺎﻌﻓ مﺪﻋ و سﺮﺘﺳا ،يا
ﯽﻤﻬﻣ ﺶﻘﻧ ﯽﻗﺎﭼ دﺎﺠﯾا رد ﯽﮑﯾﺰﯿﻓ ﻣ
ﯽﻣ ﺎﻔﯾا اﺮ ) ﺪﻨﻨﮐ
عاﻮﻧا ﻪﻠﻤﺟ زا يدﺎﯾز ﯽﻧﺎﻤﺴﺟ ضراﻮﻋ ﺎﺑ ﯽﻗﺎﭼ .(1
،ﯽﻧﻮﺧرﺎﺸﻓﺮﭘ ،ﺖﺑﺎﯾد ،نﺎﻃﺮﺳ زا ﯽﺼﺨﺸﻣ يﺮﺗ و لوﺮﺘﺴﻠﮐ ﺶﯾاﺰﻓا ،ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يرﺎﻤﯿﺑ
نﻮﺧ ﺪﯾﺮﯿﺴﯿﻠﮔ
) ﺖﺳا هاﺮﻤﻫ ﯽﺑﺮﭼ رد لﻼﺘﺧا ﻪﮐ ﺖﺴﯿﻧ ﯽﮑﺷ ﻊﻗاو رد .(3
يرﺎﻤﯿﺑ رد ﯽﻤﻬﻣ ﺶﻘﻧ ﯽﻗﺎﭼ زا ﯽﺷﺎﻧ نﻮﺧ يﺎﻫ -
ﯽﻣ ﺎﻔﯾا قﺎﭼ داﺮﻓا رد ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ ) ﺪﻨﮐ
يرﺎﻤﯿﺑ ﻪﺑ ﻼﺘﺑا ﺮﻄﺧ .(4 ﺖﻓﺮﺸﯿﭘ ﺎﺑ مﺎﮕﻤﻫ ،ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ
-
ﺎﻋ ﻪﮐ يروﺎﻨﻓ يﺎﻫ ﯽﻣ ﺮﺘﺸﯿﺑ زور ﻪﺑ زور ؛ﺪﻨﺘﺴﻫ ﯽﻗﺎﭼ ﺶﯾاﺰﻓا و ﺖﮐﺮﺣ هﺪﻨﻨﮐ دوﺪﺤﻣ ﻞﻣ
) دﻮﺷ ﻪﺑ .(5
) ﺖﺳا نﺎﻧزردﺮﯿﻣو گﺮﻣ ﻞﻣاﻮﻋ ﻦﯾﺮﺘﻤﻬﻣزا ﯽﮑﯾ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يرﺎﻤﯿﺑ ﻪﮑﯾرﻮﻃ ﻦﯿﺌﺗوﺮﭘﻮﭙﯿﻟ ﺶﯾاﺰﻓا ﻪﭼﺮﮔا .(1
) ﻦﯿﯾﺎﭘ ﯽﻟﺎﮕﭼ ﺎﺑ
LDL-c
) ﻻﺎﺑ ﯽﻟﺎﮕﭼ ﺎﺑ ﻦﯿﺌﺗوﺮﭘﻮﭙﯿﻟ ﺶﻫﺎﮐ و (
HDL-C
ﺺﺧﺎﺷ ( ﺮﻄﺧ ﻞﻣﺎﻋ و ﯽﻠﺻا يﺎﻫ
يرﺎﻤﯿﺑ ﯽﻣ بﻮﺴﺤﻣ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ شراﺰﮔ ﯽﻟو ،ﺪﻧﻮﺷ
ﯽﻣ نﺎﺸﻧ ﺎﻫ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يرﺎﻤﯿﺑ ﻪﺑ ﻪﮐ يداﺮﻓا ﺪﻨﻫد
هدﻮﺑ ﻼﺘﺒﻣ ياراد ،ﺪﻧا
HDL-C
و
LDL-C
ﺪﺷ ﻪﺘﻓﺮﯾﺬﭘ و ﺖﻓﺮﮔ مﺎﺠﻧا يدﺎﯾز تﺎﻘﯿﻘﺤﺗ ﻦﯾاﺮﺑﺎﻨﺑ .ﺪﻨﺘﺴﻫ ﯽﻌﯿﺒﻃ
يرﺎﻤﯿﺑ شﺮﺘﺴﮔ ﻪﮐ ﻪﻨﯿﻣز ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ
ﻣﻮﻤﻋ بﺎﻬﺘﻟا و دراد ﯽﺑﺎﻬﺘﻟا يا و ﻪﻌﺳﻮﺗ رد يرﻮﺤﻣ ﺶﻘﻧ ،ﯽ
يرﺎﻤﯿﺑ ﺖﻓﺮﺸﯿﭘ ﯽﻣ ﺎﻔﯾا ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ
) ﺪﻨﮐ ﻪﺑ ﺮﺘﺸﯿﺑ ناﺮﮕﺸﻫوﮋﭘ ﻪﺟﻮﺗ ﻪﺘﺷﺬﮔ ﻪﻫد رد ور ﻦﯾا زا .(3
ﺺﺧﺎﺷ يرﺎﻤﯿﺑ يﻮﮕﺸﯿﭘ ﻞﻣﺎﻋ ناﻮﻨﻋ ﻪﺑ ﯽﺑﺎﻬﺘﻟا يﺎﻫ هرﺎﺑ ﻦﯾا رد.ﺖﺳا هﺪﺷ فﻮﻄﻌﻣ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ
ﯽﻟﻮﻠﺳ ﻦﯿﺑ نﺎﺒﺴﭼ يﺎﻬﻟﻮﮑﻟﻮﻣ ناﺮﮕﺸﻫوﮋﭘ ) ﯽﻗوﺮﻋ و
sICAM-1
و
sVCAM-1 ﯽﺸﻨﮐاو ﻦﯿﺌﺗوﺮﭘ و(
)C hs-
ﺺﺧﺎﺷ ناﻮﻨﻌﺑ ار(CRP
هدﺮﮐ ﯽﻓﺮﻌﻣ ﺪﯾﺪﺟ ﯽﺑﺎﻬﺘﻟا يﺎﻫ ) ﺪﻧا
)ﯽﻟﻮﻠﺳ ﻦﯿﺑ نﺎﺒﺴﭼ لﻮﮑﻟﻮﻣ.(5
sICAM-1
و (
)ﯽﻗوﺮﻋ نﺎﺒﺴﭼ لﻮﮑﻟﻮﻣ
sVCAM-1
ﺖﯿﺳﻮﻧﻮﻣ ﻪﺑ لﺎﺼﺗا ﺎﺑ ( ﻞﯿﮑﺸﺗ ﺪﻧور ،لﺎﯿﻠﺗوﺪﻧآ ﻖﻤﻋ ﻪﺑ ﺎﻬﻧآ لﺎﺼﺗا و ﺎﻫ
ﻊﯾﺮﺳ ار ﻞﮑﺷ ﯽﻔﮐ يﺎﻬﻟﻮﻠﺳ ﯽﻣ ﺮﺗ
)ﺪﻨﻨﮐ ﺟﻮﺗﺎﺑ.(6 حﻮﻄﺳ ﺶﯾاﺰﻓا ﻪﺑ ﻪ
sICAM-1
،
sVCAM-1
و ردCRP
ﺺﺧﺎﺷ ﻦﯾا ﺶﻫﺎﮐ ﺚﻋﺎﺑ ﻪﮐ ﯽﻠﻤﻋ ﻪﻧﻮﮔﺮﻫ ،بﺎﻬﺘﻟا لﺎﺒﻧد ﻪﺑ مﺮﺳ ثداﻮﺣ ﺶﻫﺎﮐ ﺖﯿﻓﺮﻇ ،ددﺮﮔ ﯽﺑﺎﻬﺘﻟا يﺎﻫ
) دراد لﺎﺒﻧد ﻪﺑ ار ﯽﻗوﺮﻋ ﯽﺒﻠﻗ ﻪﮐ ﺎﺠﻧآزا .(4
يرﺎﻤﯿﺑ ﺰﻧژﻮﺗﺎﭘ رد بﺎﻬﺘﻟا ﺶﻘﻧ ﺖﺳا ﻦﮑﻤﻣ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ
يرﺎﻤﯿﺑ ﺶﻫﺎﮐ يﺎﻫرﺎﮐوزﺎﺳ زا ﯽﮑﯾ ﯽﺷزرو ﺖﯿﻟﺎﻌﻓ ﺪﻨﻣدﻮﺳ تاﺮﺛا ﻪﺑ ﻪﺟﻮﺗ ﻦﯾاﺮﺑﺎﻨﺑ ،ﺪﺷﺎﺑ ﯽﻗوﺮﻋ ﯽﺒﻠﻗ ﺎﻫ
ﺺﺧﺎﺷ ﺶﻫﺎﮐ و يﺮﯿﮕﺸﯿﭘ رد ﺶﻫﺎﮐ رد ﯽﻠﻤﻋ يﺎﻫرﺎﮑﻫار ﻪﻧﻮﮔ ﻦﯾا ﺖﻤﺳ ﻪﺑ ار ناﺮﮕﺸﻫوﮋﭘ ﯽﺑﺎﻬﺘﻟا يﺎﻫ
يرﺎﻤﯿﺑ نآ زا يﺮﯿﮕﺸﯿﭘ و ﯽﻗوﺮﻋ ﯽﺒﻠﻗ يﺎﻫ ﺖﺳا هداد قﻮﺳ ﺎﻫ
. ﺺﺧﺎﺷ خﺮﻤﯿﻧ ﯽﺳرﺮﺑ فﺪﻫ ﺎﺑ ﺶﻫوﮋﭘ ﻦﯾا -
ﯽﺒﻠﻗ يازﺮﻄﺧ يﺎﻫ .ﺪﺷ مﺎﺠﻧا ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ لﺎﺒﻧد ﻪﺑ لﺎﻌﻓﺮﯿﻏ قﺎﭼ نﺎﻧز ﯽﻗوﺮﻋ
شور ﻖﯿﻘﺤﺗ ﯽﺳﺎﻨﺷ
ﻖﯿﻘﺤﺗ نز40
ﻢﻟﺎﺳ ﻪﻧﺎﺒﻠﻃواد ترﻮﺻ ﻪﺑ ، رد
ﻖﯿﻘﺤﺗ ﺖﮐﺮﺷ ﺪﻧدﺮﮐ و رﻮﻄﺑ ﯽﻓدﺎﺼﺗ رد
ود هوﺮﮔ ﯽﻨﯾﺮﻤﺗ )
ﯽﻨﺳ ﻦﯿﮕﻧﺎﯿﻣ ﺎﺑ ﺮﻔﻧ20 41
/ 2
± ﯽﻧﺪﺑ هدﻮﺗ ﺺﺧﺎﺷ و ، لﺎﺳ32 29
/ 3
± و ، ((ﻊﺑﺮﻣ ﺮﺘﻣ ﺮﺑ مﺮﮔﻮﻠﯿﮐ)34
) ﺪﻫﺎﺷ هوﺮﮔ ﯽﻨﺳ ﻦﯿﮕﻧﺎﯿﻣ ﺎﺑ ﺮﻔﻧ 20
26 / 3
± ﯽﻧﺪﺑ هدﻮﺗ ﺺﺧﺎﺷ و ، لﺎﺳ32 29
/ 2
± 02 / مﺮﮔﻮﻠﯿﮐ)34
تﺪﻣ ﻪﺑ ﯽﻨﯾﺮﻤﺗ هوﺮﮔ .ﺪﻧﺪﺷ ﻢﯿﺴﻘﺗ ،((ﻊﺑﺮﻣ ﺮﺘﻣ ﺮﺑ ) ﻪﺘﻔﻫ 12
ﺎﺑ ار يزاﻮﻫ تﺎﻨﯾﺮﻤﺗ (ﻪﺘﻔﻫ رد ﻪﺴﻠﺟ 3
تﺪﺷ -75
ناﺰﯿﻣ .ﺪﻧداد مﺎﺠﻧا ﻪﻨﯿﺸﯿﺑ ﺐﻠﻗ نﺎﺑﺮﺿ ﺮﺜﮐاﺪﺣ ﺪﺻرد 65
ICAM_1 و
VCAM_1
شور ﻪﺑ
ﺖﻨﺑروزﻮﻧﻮﻤﯾا ﯽﻤﯾﺰﻧآ 1
ﻂﺳﻮﺗ
هﺎﮕﺘﺳد ElisaStatFax2100
ﺖﯿﮐ زا هدﺎﻔﺘﺳاﺎﺑ ﺖﮐﺮﺷ ياﺰﯿﻟا يﺎﻫ
BMS232 و
BMS232TEN
هداد ﻞﯿﻠﺤﺗ . ﺪﺷ يﺮﯿﮔ هزاﺪﻧا ﺪﻨﻠﻫ ﺖﺧﺎﺳ
يﺎﻔﻟآ يﺎﻄﺧ ﺢﻄﺳ رد ﺎﻫ ﻂﺳﻮﺗ و ﺪﺻرد 5
مﺮﻧ -
راﺰﻓا ﻪﺨﺴﻧSPSS
مﺎﺠﻧا18 ﺪﺷ .
ﻪﺘﻓﺎﯾ ﺎﻫ
ﺖﻈﻠﻏ ﻪﮐ داد نﺎﺸﻧ نﻮﻣزآ ﺞﯾﺎﺘﻧ ﯽﻣﺮﺳ
, sVCAM-1sICAM-1
ﯽﻨﯾﺮﻤﺗ ﻞﮑﺗوﺮﭘ زا ﺲﭘ ﯽﻨﯾﺮﻤﺗ هوﺮﮔ رد
ﻦﯿﮕﻧﺎﯿﻣ ﻪﺴﯾﺎﻘﻣ.ﺪﺸﻧ هﺪﻫﺎﺸﻣ يراد ﯽﻨﻌﻣ توﺎﻔﺗ ﺪﻫﺎﺷ هوﺮﮔ رد ﻪﮐ ﯽﻟﺎﺣ رد .ﺖﺳا ﻪﺘﺷاد يراد ﯽﻨﻌﻣ ﺶﻫﺎﮐ ﺮﯿﯿﻐﺘﻣ ﺪﻌﺑ و ﻞﺒﻗ ﯽﺳرﺮﺑ درﻮﻣ يﺎﻫ لوﺪﺟ رد يزاﻮﻫ ﻦﯾﺮﻤﺗ ﻪﺘﻔﻫ 12
.ﺖﺳا هﺪﺷ شراﺰﮔ 1 لوﺪﺟ
- 1
يﺎﻫ ﺺﺧﺎﺷ ﻦﯿﮕﻧﺎﯿﻣ ﻪﺴﯾﺎﻘﻣ ﯽﺒﻠﻗ يﺎﻬﯾرﺎﻤﯿﺑ هﺪﻨﻨﮐ ﯽﯾﻮﮕﺸﯿﭘ
ﯽﻗوﺮﻋ-
هورﮔ
رﯾﻐﺗﻣ دھﺎﺷ
ﻲﺑرﺟﺗ
لﺑﻗ
دﻌﺑ
لﺑﻗ
دﻌﺑ
(لﺎﺳ) نﺳ
23 / 1
± 32 23 / 1
±
32 41 / 2
± 32 41 / 2
± 32
BMI (kg/m2)
24 / 3 ±
06 / 34 52 / 2 ± 34 48 / 1 ± 34
# 39 / 3 ± 31
sICAM-1(ng/ml)
78 / 32 ±
8 / 280 07 / 48 ±
8 / 283 44 / 42 ±
2 / 280 32#
/ 38 ±
3 / 240
vICAM-1(ng/ml)
36 / 48 ±
7 / 725 27 / 46 ±
24 / 733 10 / 58 ±
07 / 717 93#
/ 44 ±
7 / 706
1- Immunosorbent
يﺮﯿﮔ ﻪﺠﯿﺘﻧ و ﺚﺤﺑ
يرﺎﻤﯿﺑ و ضراﻮﻋ ﺶﯾاﺰﻓا و نﺎﻬﺟ ﺮﺳاﺮﺳ رد و ناﺮﯾا رد ﯽﻗﺎﭼ هدﺮﺘﺴﮔ عﻮﯿﺷ ﻪﺑ ﻪﺟﻮﺗﺎﺑ نآ زا ﯽﺷﺎﻧ يﺎﻫ
شور ﺖﺧﺎﻨﺷ و ازﺮﻄﺧ ﻞﻣاﻮﻋ ﺪﻧاﻮﺘﺑ ﻪﮐ ﯽﯾﺎﻫ
ﯽﻣ ،ﺪﻫد ﺶﻫﺎﮐ قﺎﭼ داﺮﻓا رد ار نآ زا ﯽﺷﺎﻧ ضراﻮﻋ زا ﺪﻧاﻮﺗ
.ﺪﺷﺎﺑ ﻪﺘﺷاد ﯽﻤﻬﻣ رﺎﯿﺴﺑ يﺎﻫدﺮﺑرﺎﮐ ﯽﻨﯿﻟﺎﺑ ﺮﻈﻧ ﻪﺘﻓﺎﯾ
يﺎﻫ ﺶﻫوﮋﭘ ﺮﺿﺎﺣ
نﺎﺸﻧ داد ﻢﻈﻨﻣ ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ
ﺐﺟﻮﻣ ﯽﯾﺎﻤﺳﻼﭙﺸﻫﺎﮐ ﺮﯾدﺎﻘﻣ
ﺺﺧﺎﺷ يﺎﻫ ﯽﻗوﺮﻋ ـ ﯽﺒﻠﻗ يازﺮﻄﺧ رد
نﺎﻧز قﺎﭼ ﯽﻣ
،دﻮﺷ ﻦﯾا ﺶﻫﺎﮐ ﯽﻣ -
ﺪﻧاﻮﺗ رد يﺮﯿﮕﺸﯿﭘ زا
وﺮﺑ ز يرﺎﻤﯿﺑ يﺎﻫ ﯽﺒﻠﻗ ﯽﻗوﺮﻋ ﺮﺛﻮﻣ ﻊﻗاو دﻮﺷ .
ﻊﺑﺎﻨﻣ 1- Geffken DF, Cushman M, Burke G, Polak J, Sakkinen P, and Tracy RP. Association between physical activity and markers of inflammation in a healthy elderly population.
American J. Ofepidemiology.2001; 153(3), 242-50.
2- Rankovic G, B. Milicic, T. Savic, B. Dindi, Z. Mancev, G. Pesic., “Effects of physical exercise on inflammatory parameters and risk for repeated acute coronary syndrome in patients with ischemic heart disease”. 2009; Vojnosanitetski Pregled, vol. 66, no. 1, pp. 44- 48
3-Taheri L. The Effects of 8week aerobic exercise on blood lipoprotein of non-athletic middle-aged women of ahvaz. Harakat. 2007; 9(1):87-99. (Article in Persian)
4- Kishali NF, Imamoglu O, Kaldirimci M, Akyol P, Yildirim K. Comparison of lipid and lipoprotein values in men and women differing in training status. Int J Neurosci. 2005 Sep;
115(9): 1247-57.
5- Faghih Sh, Eghtesadi SH. Assessment of the prevalence of central and general obesity among female students of Velenjak dormitory of Shahid Beheshti University. Iranian Journal of Diabetes And Lipid Disorders 2005; 4(3):67-73
6-Ghanbari-Niaki A, Khabazian, BM, Hosseini-Kakhak SA, Rahbarizadeh F , Hedayati M.Treadmill exercise enhances ABCA1 expression in rat liver. Biochemical and BiophysicalResearch Communications.2007; 361: 841-846
