Y HOC VIET NAM THANG 6 - SO 1/2014 TCL do di tat chiem t y le cao cho thay nguyen
nhan BTTS d Phu Cat lien quan den DTBS, vi thai bi dj tat cung la nguyen nhan cua ST, TCL va sinh con bi di tat; chinh vi vay con bj DTBS du'dc sinh ra chi 1^ nhiJng thai nhi cdn song sdt. Nhu' vay, cac nguyen nhan gay DTBS d Phu Cat gdp phan chu yeu vao TCL d day.
Nghien culi cung ghi nhan du'dc la khoang thdi gian tir khi bieu hien ca benh BTTS den khi thong tin nay du'dc ghi nhan bien thien kha cao, tu' trong vdng 1 tuan cho den.hang n a m ; trong dd trong vdng 1 tuan la 3 7 , 7 8 % ; co 2,2^/o tru'dng hdp sau mpt nam mdi bao cao (bieu do 3). Thdi gian bao cao qua lau se khdng mang ti'nh thdi sy", cap nhat thdng tin se cham tre. Tuy nhien phan tich sau hdn cho thay cac tu'dng hdp bao cao lau chu yeu la DTBS ma cd the phat hien mupn hdn trong qua trinh phat trien ca t h e ; tnang tru'dng hdp DTBS chu'c nang hoac bat thu'dng hinh the nhu' tim bam sinh cd khi cung phat hien mupn tren lam sang.
Bu'dc dau chung tdi cung theo ddi mpt so tru'dng hdp sinh con bj DTBS. Phat hien 67 ca DTBS (bang 2) chu yeu la cac dj tat ve hinh the.
Trong dd, tat tim bam sinh ddn thuan chiem 17,91% tong so dj tat; tim bam sinh phat sinh chu yeu do cd che di truyen da nhan t o , chung tdi cho rang can cd nhu'ng nghien cu'u sau hdn vi ty le cao cua loai dj t a t nay. Chung tdi cung phat hien mpt sd dj tat ve chu'c nang nhu' thieu nang tuyen giap chiem 7,45%. Ben canh phat hien, mpt so tu' van can thiep cung du'dc su" dung.
Tru'dc day cac dj tat thu'dng du'dc phat hien mudn, khi du'dc phat hien cung chi/a du'dc xu' ly gi nhu'ng nay mdt so tru'dng hdp du'i^c phat hien rat sdm nen du'dc tu' van can thiep cung rat sdm.
Nhu* vay, qua theo doi dpc 2 nam cac ket qua cho thay mii'c dp 3 dang BTTS cua Phu Cat van d miTc cao. SLT ghi nhan cDng xac djnh du'dc ty le
mot so BTTS, nguyen nhan cua TCL, thdi gian bao cao BTTS. Cac so lieu nay la can thiet cho lap ke hoach y te va la c d sd cho cac nghien oili djch te hpc phan ti'ch sau h d n .
V . KET LU^N
Thong tin ve BTTS cd t h e du'dc ghi nhan tir cpng dong diXa vao he thong y t e cd sd. Dyla vao h i thong nay, nam 2012 chung toi thu du'dc ket qua d Phu Cat - Binh Dinh nhu* sau:
- Ty le ST, TCL, DTBS lan lutft la: 5,85%; 0,91% vJ 1,32% tren tong so thai da ket thuc. 63,04% thsi chet lull khdng ro nguyen nhan; 21,74% thai dift lulj la do di tat bam sinh. BTTS 1 lan: 83,66%;J lan: 12,93%; 3 lan: 2,44%; 4 -5 lan: 0,97%. ? - 56,72% tre bj dj t a t du'dc ghi nhan da duWcW van can thiep, trong d d 2 6 , 8 7 % tre bj di tat (S du'dc can thiep.
T A I LIEU THAIVI K H A O
1 . I n s t i t u t e o f Medicine (1995). Adverse Reproductive Outcomes in Families of Atonic Veterans: The Feasibility of Epidemiologic Studies, National Academy Press. Washington D.C., 42 - 43.
z. Bo Y t e ( 2 0 1 3 ) . Bao cao chung tong quan nganh Y te nam 2013. Ha Noi. , • 3. Bg Y t e ( 2 0 0 9 ) . Quyet djnh so 3440/2009/CJ'
BYT ngay 17 thang 09 nam 2009 ve v i i c j a n hm he thong so sach, bieu mau thong kS y tS. .M 4. Bo Y t e ( 2 0 0 9 ) . Hu'dng d i n Quoc gia ve cac im
vu cham soc su'c khde sinh san. Ha Npi. '^
3. World Health Organization ( 2 0 1 ^ International Statistical Classification of Disea^
and Related Heaith problem. Geneva (ICD-tffI
Tenth Revision. * 6. Tr|nh Van Bao va cs ( 2 0 0 6 ) . Tu* van di truyen:
bien phap han che sinh con di tat bam sinh. 7?p chi doc hoc, '2(2006), 14 - 2 1 .
/ . Trung t d m Y t e Phu Cat ( 2 0 1 0 , 2011). Bao cao hoat dong cham sdc tre em toan huyen nam 2010 (bieu so 4/BMTE-H).
TY LE NHIEM VIRUS VIEM GAN B 0" CAN BO VIEN CHU'C TAI HA NOI
T O M T A T
Viem gan virus B la mot trong nhiJng benh lay truyen hay gap tren the gidi, hdn mgt trieu ngu'di chet moi nam vi cac benh ly gan nang iien quan tdi virus viem gan B. Viet Nam ta nu'dc cd ty le nhiem virus
* Tnfdng Dai hgc Y Ha Noi
Phan bien khoa hoc: PGS.TS Pham Thi Thu Ho
Ph^in Thi Ng9c Bich*, Dao Van Long*
viem gan B cao. Muc t i e u : xac dinh ty le nhiem ^ viem gan B d can bg vien churc tai Ha Npi nam 20tt Phu'dng phap nghien cuTu: Nghien culJ md t& 9 ngang du'dc tien hanh tren 4325 can bo vien chOC m kham su'c khde di.nh^ky tai Benh vien Dai hgc Y Hi N | Ket qua: Ty le nhiem virus viem gan B la 8%. TV) nhiem virus viem gan B d nam (59,3%) cao hdn ctW (40,7%) (p<0,05). Nhdm tuoi tiT 18 den 39 tu6l c6tj le nhiem virus viem gan B cao nhat. Enzym gan AST
Y HQC VIET HAM THANG 6 - SO 1/2014 va ALT tang d nhdm cd HBsAg duWng tfnh cao hdn
nhom cd HBsAg am tinh (16,3% so vdi 7%, p<0,001) (15,7% so vdi ^14,3, p<0,001). Nhom HBsAg du'dng tinh ra thay doi ve cau true cua gan tren sieu am nhieu hdn nhom HBsAg am tfnh (2% so vdi 0 , 1 % , p<0,001). Ket luan: Ty le nhiem vfrus viem gan B d can bg vien chu'c d Ha ngi con tu'dng ddi cao (8%).
CSn ting cu'dng cac chinh sach phong ngCra nhiim virus viem gan B d ngu'di ldn.
Ttt khoa: HBsAg du'dng tfnh, nhiem virus viem gan B, can bg vien chu'c.
SU MARRY
THE PREVALENCE OF H E P A T I T I S B V I R U S AMONG OFFICE STAFF I N H A N O I Hepatibs B is one of the common communicable diseases in over the world, over one million people die each year because of severe liver diseases related to Hepatitis B virus. The prevalence of hepatitis B virus is high in Vietnam. Objective: To determine the prevalence of hepatitis B virus at office staffs in Hanoi in 2011. Methodology: A cross-sectional study design was done in 4325 office staffs who came to Hanoi Medical University Hospital for health check - up.
Result: Prevalence of Hepatitis B virus was 8%.
Prevalence of Hepatitis B virus in male at 59.3% was significantly higher than that in female at 40.7% (p <
0.05). The prevalence of Hepatitis B virus at age from 18 to 39 was the highest proportion. The proportion of elevated AST was higher in HBsAg-positive (16.3%) compared with HBsAg-negative (7%) (p <0.001). The proportion of elevated ALT was higher in HBsAg- positive (15.7%) compared with HBsAg-negative (14.3%) (p <0.001). The change in structure of Uie liver on ultrasound was higher in HBsAg-positive (2%) compared with HBsAg-negative (0,1%) (p <0.001).
Conclusion: The prevalence of Hepatitis B virus among office staff in Hanoi was relatively high (8%). It is necessary to strengthen policies for prevention of hepatitis B virus infection in adult.
Keywords: HBsAg- positive, Hepatitis B virus infection, office staff
I. DAT V A N D 1
Viem gan virus B la mpt trong nhiJng benh lay truyen hay g3p tren the gidi, hdn mot t r i | u ngu'di chet moi n5m vi cac benh ly gan nang lien quan tdi Virus viem gan B (HBV). Toan cau cd khoang 2 ty ngu'di tirng bj nhiem HBV, trong sd dd khoang 350 trieu ngu'di mang HBV man ti'nh v^ hang n3m cd tdi 50 trieu ca nhiem mdi va khoang 2 trieu ngu'di chet moi nSm do HBV [ 4 ] . III. K I T Q U A NGHIEN CU'U
3 . 1 . T h o n g t i n c h u n g c u a d o i t u ' a n g n g h i e n cu'u
Trong sS 4325 can bo vien chu'c den kiem tra su'c khoe djnh ky cd 5 3 % la can bo nam va 4 7 % \h dn bo niJ.
Hinii 1: Phan bo ve gidi
Viet Nam la nuiic ro ty le nhiem HBV cao. Mot tong hdp hdn 20 nghien culj dich te hpc ve viem gan B cho thay rang ty le nhiem HBV trong doi tu'dng khde manh dao dpng tu" 5,7% den 24,7%
tuy vao thiet ke nghien cu'u va doi tu'dng nghien cull [ 5 ] [ 7 ] . Ty le benh nhan bj nhiem HbsAg ( + ) trong nhdm benh nhan viem gan la 64,8% [ 5 ] . Nhu* vay virus viem gan B la can nguyen chi'nh gay cac benh ly viem gan virus.
HBV la hang dau nguyen nhan gay ra benh gan man tfnh , bao gom ca x d gan va ung thu' bleu mo te bao gan (HCC). Tren toan cau, 3 0 % xd gan va 53 % cac tru'dng hdp HCC la do HBV^
Ung thu* gan la mpt trong nam loai ung thu* pho bien tren the gidi, hang nam cd tren 500.000 tru'dng hdp ung thu* gan mac mdi du'dc phat hien. Tai Viet Nam, ung thu' gan d nam gidi duTig hang tu' 3 sau ung thu'phoi va ung thu' da day. O niJ gidi ung thu' gan du'ng hang thi? 5. Hien nay cd rat nhieu tien bd trong chan doan, dieu trj x d gan va ung thu' gan tuy nhien Hnh vu'c phdng ngiTa nhiem virus viem gan B van cdn nhieu thach thuTc.
Kiem tra sii'c khoe dinh ky la mot trong nhuTig thdi quen tot trong cham sdc y hoc. Vdi su* phat trien cua nen kinh te thj tru'dng va nhu cau ch3m sdc SLTC khoe cua ngu'di dan ngay cang tSng, viec thu'c hien kham va kiem tra sire khoe djnh ky la mpt trong nhutig hoat dpng khong the thieu du'dc cua ngu'di dan, diic biet la khdi can bp vien chiVc tai cac doanh nghiep va cd quan. Kiem tra su'c khoe djnh ky giup phat hien va chan doan sdm benh t i t tir dd cd nhiJng bien phap phdng benh kjp thdi. Xuat phat tir thu'c tien tren chiinp tdi tien hanh nghien cirtj "Xac dinh ty ie nhiem virus viem gan B dl can bo vien diiyc tai Ha Ngi".
II. OOI T U p N G VA PHU'ONG PHAP NGHIEN COU 2 . 1 . O o i t u ' d n g n g h i e n cu'u
4325 can bd vien chu'c tai 70 cdng ty/cd quan tai Ha Noi du'dc kham kiem tra su'c khoe dinh ky tai benh vien Dai hoc Y Ha ndi trong thdi gian tCr 1/2011 den 12/2011.
2.2. Phu'dng p h a p n g h i e n cu'u Nghien cCru mo ta cat ngang. Phan tich so lieu: sir dung phan mem STATA 12.0.
59
Y Hpc VliT NAM THANG 6 - S01/2 Hinh 1: Phan bo ve gi6i
Hinh 2: Phan bo theo nhom tuoi
T y l e C°/o)
II..
T i r 1 8 l i e n 2 9 T u - 3 0 U i ? i i 3 9 :) t l c i i 1>J T r t - i i 5 0 I
Hinh 2 cho thay, nhdm tuoi chiem ty 1$ cao nhatii nhdm tir 18 den 29 tuoi chiem ty I? 41,1 %, nhfm chiem ty li thap nhat li nhdm trin 50 tuoi chiem 9,6%
3.2.1V1$ nhlSm Virus ViSm gan.B Hinh 3; Ty I? nhilm Virus viem gan B
Trong so 4325 cin bo cong chut dude kiem tra co 8% can bd viin chu'c cd HBsAg dudng tinh, tras do cd 59,3% d nam gidi va 40,7% d nO'gidi. Ty li nhiem vi rut viim gan B d hai nhdm nam va m khic nhau co y nghla thong ke vdip <0. OS.
Bingl;J<i le nhiem virus Viem gan B theo nhom tuoi
Nhbm tuoilii 18 aen 29 TO 30 aen 39 TO 40 den 49 Tren 50 tuoi
Tong
T v l ? { % ) HBsAg ( 0
41,4 36,2 12,3 10,1
100T y l f { % ) HBsAg ( + )
38,8 41,3 14,6
5,3 100p=o,aoB
Bang 1 chi ra tang ty le HBsAg dutfng tinh d nhom tuoi tif 30 den 39 la cao nhat (41,3%), tiep den la nhom tu* 18 den 29 tuoi chiem 38,8%, nhom tuoi tren 50 tuoi co ty le HBsAg du'dng tinh thap nhat (5,3%). Su* khac nhau ve ty le HBsAg du'dng tinh is
cac nhom tuoi co y nghTa thong ke vdi p = Oj
Tuy nhien khong cd moi lien quan ty IS thu$n
ty le HBsAg du'dng tinh va nhom tuSi, khong
khi tuoi cang cao thi ty le HbsAg dudng tinh
tang (OR=0,95,95% Q; 6,84 -1,06).
Y HOC VI§T NAM THAHG 6 - SO 10014
3.3. Cdc bi^n do! v^ Enzym gan va hinh anil thay doi cau true gan tren sieu am Bang 2: Bien doi enzvm aan va hinh anh sieu am aan
Benli nhan Tyle HBsAq Am ti'nh ( %)
Tyle HBsAq Du'dng tinh (%)
P
AST (Aspartat transaminase)
S37 UI/I 93 83,7
> 37 UI/I 7 16,3 p = 0,000
ALT (Alanin transaminase)
< 40 UI/I 85,7 68,3
>40 UI/
14,3 15,7 p = 0,000
Sieu am gan Binh thu'dnq
99,9 98
Bat thudnq 0,1
2 p = 0,000 Sieu am gan bat thu'dng d trong nghien cihj
nay la bieu hi$n tren siSu am cd cac nhu mo gan tho, theo dol xd gan, hoac xd gan un^ Uiu* hoa.
Trong nghien CLTU nay chii yeu la bien doi nhu mo gan tho^ khdng cd tru'dng hdp nao xd gan ung thu* hoa. Cac ket qua sieu am gan cd nang gan, u m^u d gan va cac van de khac d gan khonq xep vao sieu am gan bat thu'dng.
Banci 2 chi ra rSng cd 16,3% ngu'di HBsAg dutjig tmh cd AST tSng, tuy nhien d ng\ipi khdng nhiem vl rut viem gan B ty le AST tang van chiem 7%. Cd 15,7% ngu'di co HBsAg du'dng tinh cd ALT tang,^cdn 14,3 % ALT tSng d nhom ngu'di khong nhiem virus viem gan B. Enzym gan (AST vh ALT) tSng d nhdm cd HBsAg du'dng tinh cao hdn nhdm HBsAg am ti'nh. SLT khac biet cd y nghla thong ke (p=0,000). Ve thay doi ve cau true cua gan tren sieu am chung toi thay rang tren nhdm cd HBsAg du'dng tfnh, cd 2% benh nhan da cd thay doi cau true cua gan tren sieu Sm gan, cd 0,1% cd thay ddi cau trCic cua gan trSn nhom HBsAg Sm tfnh,
IV. BAN LUiBiN
Qua nghi§n cihj 4325 ngu'di khoe manh di khim klSm tra siJc khoe <Jlnh ky tai benh vi?n Dal hpc Y Hh Npt chCing toi thay ran^ ty I? HBsAg du'dng ttnh chiem 8% tong sd cac tru'dng hdp nghiSn ciili. Trong dd ty I? HBsAg duUng ti'nh d nam cao hdn so vdl nlj', SM' khac nhau nay cd y nghTa thdng ke vdi p<0,05. Ket qua cua chung tdl cung giong vdi ket qua cua mot sd nghien cub trong nu'dc va qudc te. Ty te nhiem vi rut viem gan B d Vi?t nam dao ddng tij* 5,7 % den 24,7%
tuif tiTng doi tu'dng nghien culi [7].
Tlieo bSo cao cua to chu'c y te the gidi nSm 1999, ty 1^ HBsAg du'dng tinh d Dong Nam A tCr 8% trd ISn. Mot so nu'dc nhu" Thai Lan ty le HBsAg duWng tinh cung dao ddng tii 8%-16%, H^n Quoc d ty I? nSy thap hdn {tif 4,1% den 8,4%) [2][3][6]. Mpt so nyidc khac cd ty le HBsAg duWng tinh thap la Uc va New Zealand (<1%). 6 Vl|t nam ta hien nay chung ta da ap dgng chuWng trinh tiem chung md rong de phdng ChSng b$nh viSm gan virus B, tuy nhien dol tuii?ng duVc tl&n phdng tap chung chu yeu la cac
chau nhd du'di 6 tudi, doi tu'dng ngu'di Idn chiia du'dc quan tam, viec phdng chdng cac benh nay chu yeu la tiT phat. Vi vay mpt ty le khdng nhd cac ddi tu'dng khoe manh la ngu'di lanh mang virus viem gan B ma khdng biet minh nhiem benh, vi vay hp chu^a cd y thu'c trong viec phdng ngiia lay lihiem benh cho ngu'di khac cung nhu' theo doi benh cho ban than.
Ket ciua trong nghien ciiu cua chung toi cung chi ra rang ty te nhiem virus viem gan B d nam cao hdn cd y nghTa so vdi d ni?. Ket qua nay cung tu'dng tii nhii mpt vai nghien ciiu d trang nu'dc va qudc te [1], tuy nhien mpt so nghien cCTu khac chi ra rang tuoi cang cao thi ty le nhiem virus viem gan B cang tang [1], ket qua nay khdng giong vdi cac ket qua trong nghien culi cua chiing tdi. Tuy nhien, tuoi la mpt trong nhOtig yeu to cd lien quan vdi ty 1$ nhiem virus viem gan B [1], mpt vai nghien ciiii chl ra ring, ty le HBsAg du'dng tinh hay gap nhat d nhdm tuoi vj thanh nien, mpt so nghien CLTU khac thj thay rSng ty le nay hay gap d nhdm tif 25-35 tuoi va nhdm tu' 20-40 tuoi. Ket qua trong nghien ^aiti cua Chung toi cung thay rang ty I? nhom tuoi cd ty le HBsAg du'dng ti'nh cung gap d nhdm tuf IB iin 39 tuoi.
Chi sd enzym ^an AST va ALT ta mpt trong cac chi so danh gia chu'c nang gan, trong nghien cull nay chunq toi thay rang emzym gan t3ng nhdm ngu'di co HBsAg du'dng ti'nh nhieu hdn cd y nghTa so vdi nhdm ngu'di HBsAg am tinh, cd tdi
>15% benh nhan cd AST va ALT tang d nhdm cd HBsAg du'dng tfnh. Tren sieu am gan cung cho thay rang co 2% benh nhan cd HBsAg du'dng tfnh cung cd cac thay ddi ve cau true nhu mo gan. Enzym gan tang^ cd the gSp trong cac tru'dng hdp: uong nhieu bia n/du, diing thuoc hoac cac benh Iy khac tu^ nhjeri cac chi so vie tang enzym gan va sir bien doi ve nhu mo gan trong sieu am tren cac benh nhan cd HBsAg du'dng tfnh se la mpt trang cac chf so tiidng bao sdm giup gdl^y chan doan viem gan B man tinh.
Tuy nhien de chan doan xac djnh benh nhan cd viem gan B man tinh hay khong can phai lam them cac xet nghiem chuyen sau khac nhU:
HbeAg, antiHbe, HBVDNA hoac sinh thiet gan...
Y HOC VIET NAM THAHG 6 - SO 1/2014 V.KETLUAN
Ty le nhiem virus viem gan B cua can bo vien chu'c den kham SLTC khde tai Benh vien Oai hpc Y Ha Npi la 8 % . Ty ie nhiem virus viem gan B d nam cao hdn cd y nghia so vdi^d nU (59,3%^so vdi 40,7%, p<0,05). Nhdm tuoi cd t / ie nhiern virus viem gan B hay gap tii 18 den 39 tudi, (tir 18-29 tudi ia 38,8% va tir 30-39 tuoi la 41,3%).
Enzym gan tang (ca AST va ALT) d nhdm cd HBsAg du'dng tinh cao hdn nhdm cd HBsAg am tfnh (AST tang d hai nhdm HBsAg du'dng tinh va am tmh la 16,3% so vdi 7%, p<0,001) (ALT tang d hai nhdm HBsAg du'dng tinh va am tfnh la 15,7% so vdi 14,3, p<0,001). Nhdm HBsAg du'dng tinh cd thay ddi ve cau true cua gan tren sieu am nhieu hdn nhdm HBsAg a m tinh ( 2 % so vdi 0 , 1 % , p<0,001).
T A I L I | U T H A M KHAO
1. Hipgrave, D. B., Van, N. T., Huong, V. M., Long, H. T., Dat, D, T., Trung, T. N., Jolley, D., Maynard, 3. E. & Biggs, B.-A. (2003).
Hepatitis B Infection in rural Vietnam and the implications for a national program of infant
immunisation. Am J Trop Med Hyg, 69, 288-94.
2. Jee, S. H., Ohrr, H., Sull, 3. W. & Saitiet, 3. M (2004). Cigarette smoking alcohol dhnkini hepatitis B, and risk for hepatocellular carcinon^
In Korea. J Natl Cancer Inst, 96, 1851-56.
J . Lee, D. H., Kim, 3. H., Nam, 3. 3., Kim, H. R. &
Shin,'H. R. (2002). Epidemiological findings of, hepatitis B infection based on 1998 National' Heaith and Nutrition Survey in Korea. J Korean Med SCI, 17, 457-62.
4. Milich D, L.T.,(2003). Exploring the biological basis of hepatitis B e antigen in hepatitis B virus Infection. Hepatology. 38: p. 1075-1086.^
5. Trinh Thi Ngoc ( 2 0 0 1 ) . Tinh trang nhiem cacvi rut viem gan: A, B,C, D, E d cac benh nhan viem gan vi rut tai mpt sd tinh phfa Bac Viet Nam, LuSn an tien sy y hgc.
6. Pichainarong, N., Chaveepojnkan^orn, W,, Luksamijarulkul, P., Sujirarat, D, ft Keereecamsuk, T. ( 2 0 0 3 ) . Hepatitis 8 carrier among married Hilltribe women in Northern Thailand. Southeast Asian J Trop Med PulDlic Health, 34,114-19.
7. Van T.T.Nguyen (2012). Hepatitis B in%:tion in Vietnam: Cun-ent Issues and Future Challenges.
Asia-Pacific Joumal of Public Health, 24(2) 361- 37
MOT SO DAC DIEM LAM SANG VA DICH TE HOC COA B 6 N H MAY DAY MAN TINH DIEU TRI TAI BENH VJEN 103
J6M TAT
Nghien cCiU 135 benh nhan Ban may day man ti'nh den khdm va dieu h i tai Benh vien 103 tir thang 8/2012 den thang 7/2013, ket qua cho thay; Ti le % b^nh nh3n m&y day man tfnh trong dp tudi tir 20-49 la 66,6%. Ti le benh d nam va nij* bSng nhau. Sd benh nhan cd tiBn sOf dj litig chiem 94,1%. Benh may day man ti'nh cd the xuat hien quanh nam. Benh gSp nhieu nhat vao mua he (37%). Oa so tru'dng iidp mic benh trong vdng 1 n3m chiem 69,6%. So tru'dng hdp mSc tren 5 nSm la 11,1%. Mu'c dp benh nling chiem ti le 65,9%, mu'c dp viia chiem 31,9% va mu'c dp nhe la 2,2%. Cd 14 yeu to thuan ldi cho viec xuat hien benh, trong do yeu td thdi tiet chiem ti le cao nhat 60,7%.
Cd 34,8% tru'dng hdp khong tim thay yeu to lien quan.
TO'khoa: Benh da tieu, Benh may day man tinh.
* B$nh vi$n Da lieu Thanh Hoa
** HQC w$n Quan y
Phan bipn khoa hgc: PGS.TS Tran Dang Quyet
Hoang Van M^nh'^, Pham Hoang Kham**
SUIVIMARY
SOME C L I N I C A L A N D EPIDEMIOLOGICAL CHARACTERISTICS W I T H CHRONIC
U R T I C A R I A WERE TREATED I N 1 0 3 HOSPITAL
Study of 135 patients with chronic urticaria wtio were examined and treated in 103 Hospital, from August, 2012 to July, 2013, the results showed tiiat;
The percentage of the patients with chronic urticaria from 20-49 years old was 66.6%. The rate of males and females was equal. Personal allergic history was;
94.1%, Chronic urticaria occur all year round. Titt percentage of the patients with chronic urticaria in tiie summer was the highest (37%). Most of the patients suffer from Chronic urticaria within a year (69,6%).
The rate of patients who were ill over 5 years was 11,1%. The level of severity disease was 65,9%, moderate: 31,9% and lighter was 2.2%. There were 14 favorable factors to occurrence of the disease.
